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    Crosslinked (meth)acrylamide particles, process for their production and their use
    1.
    发明授权
    Crosslinked (meth)acrylamide particles, process for their production and their use 有权
    交联的（甲基）丙烯酰胺颗粒，其生产和使用的过程

    公开(公告)号：US07659348B2

    公开(公告)日：2010-02-09

    申请号：US11247157

    申请日：2005-10-12

    申请人： Kazuaki Muranaka ,  Maho Yamanaka ,  Kosuke Araki

    发明人： Kazuaki Muranaka ,  Maho Yamanaka ,  Kosuke Araki

    IPC分类号： C08F20/56 ,  C08C19/22 ,  G01N30/02 ,  B01D15/34

    CPC分类号： B01J39/26 ,  B01J20/261 ,  B01J20/267 ,  B01J20/28004 ,  B01J20/285 ,  B01J41/20 ,  B01J43/00 ,  B01J2220/54 ,  C08F8/00 ,  C08F220/58

    摘要： Crosslinked (meth)acrylamide particles in the form of substantially spherical fine particles having particle sizes of from 1 to 1000 μm made of a polymer of a N-alkoxymethyl(meth)acrylamide and a polyfunctional unsaturated monomer copolymerizable with the N-alkoxymethyl(meth)acrylamide, wherein the structural units derived from the N-alkoxymethyl(meth)acrylamide are crosslinked by a crosslink having a structure represented by the formula 1 (wherein X is hydrogen or a methyl group, and each of R8 and R9 is another structural unit derived from the N-alkoxymethyl(meth)acrylamide and bonded to the nitrogen atom in another structural unit derived from the N-alkoxymethyl(meth)acrylamide monomer via a methylene group).

    摘要翻译： 交联的（甲基）丙烯酰胺颗粒，其形式为粒径为1-1000μm的基本上为球形的细颗粒，其由N-烷氧基甲基（甲基）丙烯酰胺和可与N-烷氧基甲基（甲基）丙烯酸烷基酯共聚的多官能不饱和单体制成， 丙烯酰胺，其中衍生自N-甲氧基甲基（甲基）丙烯酰胺的结构单元通过具有式1表示的结构的交联（其中X是氢或甲基，并且R 8和R 9各自是衍生自 由N-烷氧基甲基（甲基）丙烯酰胺和通过亚甲基与N-烷氧基甲基（甲基）丙烯酰胺单体衍生的另一结构单元中的氮原子结合）。

    CELL SELECTION APPARATUS, AND CELL SELECTION METHOD USING THE SAME
    4.
    发明申请
    CELL SELECTION APPARATUS, AND CELL SELECTION METHOD USING THE SAME 审中-公开
    细胞选择装置和使用该细胞选择装置的细胞选择方法

    公开(公告)号：US20110033910A1

    公开(公告)日：2011-02-10

    申请号：US12937603

    申请日：2009-04-15

    申请人： Maho Yamanaka ,  Takahiro Maruyama ,  Toru Futami

    发明人： Maho Yamanaka ,  Takahiro Maruyama ,  Toru Futami

    IPC分类号： C12N13/00 ,  C12M1/42

    CPC分类号： G01N33/5438 ,  G01N33/569

    摘要： The cell selection apparatus includes: a cell selection vessel which has a pair of electrodes and a sheet-like insulating material having a plurality of micropores, with a recognition molecule bindable to the specific substance being disposed on a bottom face of the micropore; and a power supply, wherein the power supply includes a cell-immobilization power supply and a cell-taking power supply. The cell selection method uses the cell selection apparatus, including; introducing cells into a cell selection area; immobilizing these cells in the micropores; effecting a binding reaction between the specific substance and the recognition molecule; thereafter, taking out a cell of which the specific substance is not or is weakly bound to the recognition molecule, from the micropore; otherwise alternatively, leaving a cell of which the specific substance on the surface of the cell is strongly bound to the recognition molecule, behind in the micropore.

    摘要翻译： 细胞选择装置包括：具有一对电极的细胞选择容器和具有多个微孔的片状绝缘材料，具有与所述特定物质结合的识别分子设置在所述微孔的底面上; 以及电源，其中所述电源包括电池固定电源和单电池电源。 小区选择方法使用小区选择装置，包括： 将细胞引入细胞选择区域; 将这些细胞固定在微孔中; 实现特定物质与识别分子之间的结合反应; 此后从微孔中取出特定物质不与识别分子结合的细胞; 或者，留下细胞表面上的特定物质的细胞与识别分子强烈结合在微孔后面。

    Crosslinked (meth)acrylamide particles, process for their production and their use
    5.
    发明申请
    Crosslinked (meth)acrylamide particles, process for their production and their use 有权
    交联的（甲基）丙烯酰胺颗粒，其生产和使用的过程

    公开(公告)号：US20060084765A1

    公开(公告)日：2006-04-20

    申请号：US11247157

    申请日：2005-10-12

    申请人： Kazuaki Muranaka ,  Maho Yamanaka ,  Kosuke Araki

    发明人： Kazuaki Muranaka ,  Maho Yamanaka ,  Kosuke Araki

    IPC分类号： C08F20/56

    CPC分类号： B01J39/26 ,  B01J20/261 ,  B01J20/267 ,  B01J20/28004 ,  B01J20/285 ,  B01J41/20 ,  B01J43/00 ,  B01J2220/54 ,  C08F8/00 ,  C08F220/58

    摘要： Crosslinked (meth)acrylamide particles in the form of substantially spherical fine particles having particle sizes of from 1 to 1000 μm made of a polymer of a N-alkoxymethyl(meth)acrylamide and a polyfunctional unsaturated monomer copolymerizable with the N-alkoxymethyl(meth)acrylamide, wherein the structural units derived from the N-alkoxymethyl(meth)acrylamide are crosslinked by a crosslink having a structure represented by the formula 1 (wherein X is hydrogen or a methyl group, and each of R8 and R9 is another structural unit derived from the N-alkoxymethyl(meth)acrylamide and bonded to the nitrogen atom in another structural unit derived from the N-alkoxymethyl(meth)acrylamide monomer via a methylene group).

    摘要翻译： 交联的（甲基）丙烯酰胺颗粒，其形式为粒径为1-1000μm的基本上为球形的细颗粒，其由N-烷氧基甲基（甲基）丙烯酰胺的聚合物和可与N-烷氧基甲基（甲基）丙烯酸烷基酯共聚的多官能不饱和单体制成， 丙烯酰胺，其中衍生自N-甲氧基甲基（甲基）丙烯酰胺的结构单元通过具有由式1表示的结构的交联（其中X是氢或甲基，并且R SUB 8 >和R 9是来自N-烷氧基甲基（甲基）丙烯酰胺的另一结构单元，并且通过亚甲基与N-烷氧基甲基（甲基）丙烯酰胺单体衍生的另一结构单元中的氮原子键合 ）。