公开(公告)号：US6050954A

公开(公告)日：2000-04-18

申请号：US138245

申请日：1998-08-21

申请人： Manfred Mittermeier

发明人： Manfred Mittermeier

IPC分类号： A61B17/34 ,  A61B19/00 ,  A61B10/00

CPC分类号： A61B17/3403 ,  A61B90/17

摘要： The present invention is directed to a biopsy needle orientation fixture for use in association with diagnostic mammography equipment, and in particular, a horizontal stereotactic mammography x-ray machine having a radiation source. The biopsy needle orientation fixture comprises a substantially L-shaped frame having both horizontal and vertical members. The horizontal and vertical members are joined at one end, while the second end of the horizontal member houses a vertical needle guide, and the second end of the vertical member houses a horizontal needle guide. The horizontal and vertical needle guides allow a biopsy procedure to be performed accurately along both vertical and horizontal needle pathways. The fixture further comprises a means for mounting the substantially L-shaped frame to the stereotactic mammography x-ray machine, and a displacement from alignment with the horizontal needle path in the horizontal member. This displacement from alignment allows radiation to image and identify the horizontal needle position both before and after a breast lesion is biopsied.

摘要翻译： 本发明涉及一种用于与诊断性乳房X线照相设备结合使用的活检针定位夹具，特别涉及一种具有辐射源的水平立体定向乳房X射线摄影机。 活检针取向夹具包括具有水平和垂直构件的大致L形框架。 水平和垂直构件在一端接合，而水平构件的第二端容纳垂直的针引导件，垂直构件的第二端容纳水平的针导向件。 水平和垂直针导杆允许沿垂直和水平针通路精确地执行活检程序。 固定装置还包括用于将基本上L形的框架安装到立体定向乳房X射线摄影X射线机的装置，以及与水平构件中的水平针路径对准的位移。 乳房病变活检之前和之后，来自对准的位移允许辐射成像并识别水平针位置。

公开(公告)号：US5989241A

公开(公告)日：1999-11-23

申请号：US46451

申请日：1998-03-23

申请人： Michael Plishka ,  Manfred Mittermeier

发明人： Michael Plishka ,  Manfred Mittermeier

IPC分类号： A61M25/01 ,  A61M27/00 ,  A61M37/00

CPC分类号： A61M27/002 ,  A61M25/0147 ,  A61M2025/0163 ,  A61M27/00

摘要： A drainage catheter apparatus for draining fluid from a body cavity of a patient, of the catheter type having an elongated hollow drainage member, a flexible tip, an interfacing hub member, a sealing member, a restraining member, a flexible drawing member and a retention facilitating member. The flexible drawing member capable of altering the flexible tip. This sealing member of elastomeric material seals the draw-string opening to automatically seal the opening from the passage of fluid therethrough, while enabling extension of the flexible drawing member. Similarly, the restraining member facilitates releasable restraint of the draw-string in a desired position. The retention facilitating member facilitates the proper positioning of the flexible drawing member with the restraining member and/or sealing member.

摘要翻译： 一种用于从患者的体腔排出流体的排液导管装置，具有细长的中空排泄构件的导管类型，柔性尖端，界面轮毂构件，密封构件，限制构件，柔性牵引构件和保持件 促进会员 能够改变柔性尖端的柔性绘图构件。 该弹性体材料的密封件密封了拉弦开口，以便使开口与流体的通道自动密封，同时能够延伸柔性拉丝件。 类似地，约束构件便于将拉弦的可释放的约束放置在期望的位置。 保持促进构件有助于柔性牵引构件与限制构件和/或密封构件的适当定位。

公开(公告)号：US6095967A

公开(公告)日：2000-08-01

申请号：US047715

申请日：1998-03-25

申请人： Wayne J. Black ,  Manfred Mittermeier

发明人： Wayne J. Black ,  Manfred Mittermeier

IPC分类号： A61M36/12 ,  A61N5/10 ,  A61M36/00

CPC分类号： A61M37/0069 ,  A61N5/1007 ,  A61N2005/1011 ,  A61N5/1027

摘要： An isotope seeding system that controls the release of radioactive seeds for treatment of cancerous cells during cancer treatment procedures. The isotope seeding system comprises at least one seed that is chargeable with radioactive isotopes. At least one dissolvable web netting may alternatively be positioned about the at least one seed, and a seed deployment assembly is utilized for delivering the at least one seed, with or without the dissolvable web netting, into an organism's tissue, to surround cancerous cells. The seed deployment assembly includes an elongated cannula, a hub assembly and an obturator. The hub assembly includes an initial inner diameter at its proximal end and an operable length between the proximal end of the hub assembly and the proximal end of the cannula, the ratio of the initial inner diameter relative to the operable length being in the range of 0.075 to 0.175, to preclude against jamming of the at least one seed, with or without the at least one dissolvable web netting wrapped thereabout, within the hub assembly and/or to further preclude against inadvertent migration of such seeds from the web netting when such netting is utilized.

摘要翻译： 在癌症治疗过程中控制放射性种子释放以治疗癌细胞的同位素播种系统。 同位素播种系统包括至少一种能够与放射性同位素一起进料的种子。 至少一个可溶性网状网可以围绕至少一个种子定位，并且种子展开组件用于将具有或不具有可溶性网状网的至少一种种子输送到生物体的组织中以包围癌细胞。 种子展开组件包括细长插管，轮毂组件和闭孔器。 毂组件包括其近端处的初始内径和在毂组件的近端和套管的近端之间的可操作长度，初始内径相对于可操作长度的比率在0.075的范围内 至0.175，以防止至少一种种子的干扰，有或没有包裹在其中的至少一个可溶性网状网在轮毂组件内和/或进一步防止这种种子从网状网中无意中迁移，当这种网 被利用。

公开(公告)号：US5750581A

公开(公告)日：1998-05-12

申请号：US724387

申请日：1996-10-01

申请人： Werner Brennenstuhl ,  Manfred Mittermeier ,  Wilhelm Huber

发明人： Werner Brennenstuhl ,  Manfred Mittermeier ,  Wilhelm Huber

IPC分类号： B29C39/26 ,  B29L22/00 ,  C08J9/32 ,  C08K5/54 ,  C08K7/22 ,  C08L83/04 ,  C08L83/05 ,  C08L83/07 ,  C08L101/00 ,  C09K3/10

CPC分类号： C08J9/32 ,  C08K7/22 ,  C08L83/04 ,  C08G77/12 ,  C08G77/16 ,  C08G77/18 ,  C08G77/20 ,  C08G77/24 ,  C08G77/26 ,  C08G77/28 ,  C08G77/42 ,  C08G77/46 ,  C08G77/70 ,  C08J2203/22 ,  C08J2383/04

摘要： The invention relates to compositions which crosslink to give elastomers, have a viscosity of 1,000 to 100,000 mPa.multidot.s and are based on (A) hollow bodies of plastic and (B) crosslinkable organosilicon compounds.

摘要翻译： 本发明涉及交联以产生弹性体的组合物，其粘度为1,000至100,000mPax，并且基于（A）塑料中空体和（B）可交联的有机硅化合物。

公开(公告)号：US06063037A

公开(公告)日：2000-05-16

申请号：US137854

申请日：1998-08-21

申请人： Manfred Mittermeier ,  Alan M. Hable

发明人： Manfred Mittermeier ,  Alan M. Hable

IPC分类号： A61B10/00 ,  A61B10/02

CPC分类号： A61B10/025

摘要： The present invention is directed to a biopsy needle for extracting bone marrow from a living bone. The biopsy needle comprises an outer cannula, an inner cannula slidable therein, an obturator and an ejector rod. The outer cannula has a proximal end, affixed to a handle, and a distal end which has a tapered inner diameter. The inner cannula likewise has a proximal end, affixed to an interlocking handle, and a distal end. The inner cannula distal ends consists of a tissue receiving region and a tissue grasping mechanism. The tissue grasping mechanism comprises a resilient deformable wall with an asymmetric configuration, preferably, two opposing slits, and a structure-maintaining spanning member. The tissue grasping member is which are deformed and at least partially closed upon insertion into the tapered region of the outer cannula. In operation, this deformation severs a tissue sample into the receiving region of the inner cannula, which may then be withdrawn from a patient. A spring biased ejector rod displaces the sample from the inner cannula, while also reforming the tissue grasping portion of the inner cannula to its original pre-biopsy shape. The obturator may be used in combination with the outer cannula for initial insertion of the needle into the patient.

摘要翻译： 本发明涉及一种用于从活骨提取骨髓的活检针。 活检针包括外套管，可在其中滑动的内套管，闭塞器和顶出杆。 外套管具有固定到手柄的近端和具有锥形内径的远端。 内套管同样具有近端，固定到互锁手柄和远端。 内套管远端由组织接收区域和组织夹持机构组成。 组织抓取机构包括具有不对称构型的弹性可变形壁，优选地为两个相对的狭缝，以及结构维持跨越构件。 组织夹持构件在插入到外插管的锥形区域中时变形并且至少部分地闭合。 在操作中，该变形将组织样本切割到内套管的接收区域中，然后可以将其从患者身上取出。 弹簧偏压的排出杆将样品从内套管移位，同时还将内套管的组织抓握部分重新转换成其原始的活检前形状。 闭孔器可以与外套管组合使用以将针头初始插入患者体内。

公开(公告)号：US5998548A

公开(公告)日：1999-12-07

申请号：US135365

申请日：1998-08-17

申请人： Werner Brennenstuhl ,  Manfred Mittermeier ,  Heinz-Max Rohrmuller ,  Erhard Bosch ,  Ingomar Kovar ,  Klaus-M. Matejcek

发明人： Werner Brennenstuhl ,  Manfred Mittermeier ,  Heinz-Max Rohrmuller ,  Erhard Bosch ,  Ingomar Kovar ,  Klaus-M. Matejcek

IPC分类号： C08K3/00 ,  C08K5/36 ,  C08K5/54 ,  C08K5/5425 ,  C08K5/548 ,  C08K7/22 ,  C08K9/04 ,  C08L21/00 ,  C08L83/04 ,  C08L83/05 ,  C08L83/07 ,  C09K3/10 ,  C08F36/00

CPC分类号： C09K3/1018 ,  C08K5/5425 ,  C08K7/22 ,  C08L83/04 ,  C08G77/06 ,  C08G77/28 ,  C09K2200/0488 ,  C09K2200/0494

摘要： Compositions which crosslink to form elastomers and are based on(A) hollow polymer bodies,(B) addition-crosslinkable organosilicon compounds, and(C) organic sulfur compounds.

摘要翻译： 交联形成弹性体并基于（A）中空聚合物体，（B）加成交联的有机硅化合物和（C）有机硫化合物的组合物。

公开(公告)号：US5730724A

公开(公告)日：1998-03-24

申请号：US564383

申请日：1995-11-24

申请人： Michael Plishka ,  Manfred Mittermeier

发明人： Michael Plishka ,  Manfred Mittermeier

IPC分类号： A61M25/01 ,  A61M27/00 ,  A61M37/00

CPC分类号： A61M25/0147 ,  A61M27/002 ,  A61M2025/0163 ,  A61M27/00

摘要： A drainage catheter apparatus for draining fluid from a body cavity of a patient, of the catheter type having an elongated hollow drainage member, a flexible tip, an interfacing hub member, and further comprising a flexible drawing member capable of altering the flexible tip. A sealing member of elastomeric material seals the draw-string opening to automatically seal the opening from the passage of fluid therethrough, while enabling extension of the flexible drawing member, together with releasable restraint of the draw-string in a desired position.

摘要翻译： 一种用于从患者的体腔排出流体的排液导管装置，所述导管类型具有细长的中空排液构件，柔性末端，接口毂构件，并且还包括能够改变柔性尖端的柔性绘图构件。 弹性体材料的密封构件密封拉弦开口以将开口自动地密封流体通过其中的通道，同时能够延伸柔性拉丝构件，同时可将牵引绳的可释放限制放置在所需位置。

公开(公告)号：US5507298A

公开(公告)日：1996-04-16

申请号：US311507

申请日：1994-09-23

申请人： John B. Schramm ,  Manfred Mittermeier ,  Alan Hable

发明人： John B. Schramm ,  Manfred Mittermeier ,  Alan Hable

IPC分类号： A61B10/00 ,  A61B10/02

CPC分类号： A61B10/0275 ,  A61B2010/0208

摘要： An apparatus for the automated and facilitated handling and operation of a biopsy needle system, having a first needle component and a second needle component. The first and second needles are provided with first and second handles, respectively, which are fitted into first and second yokes of the apparatus. The apparatus is configured to maintain the first and second needles in a first position, during insertion of the biopsy needle point into the tissue being sampled. The apparatus is further configured to forwardly move the first and second needles into subsequent positions, respectively, in rapid, automated succession so as to segment and enclose a tissue sample, which may be tested after removal of the biopsy needle system from the tissue. A tissue sample inspection feature permits facilitated repositioning and maintenance of the first needle relative to the second needle after retrieval of the tissue sample to, in turn, enable inspection of the retrieved tissue sample without removal of either needle from the apparatus. The apparatus is further configured so as to be actuatable from positions adjacent the front or the rear of the apparatus housing.

摘要翻译： 一种用于自动且便利地处理和操作活检针系统的装置，具有第一针部件和第二针部件。 第一和第二针分别设置有装配到装置的第一和第二轭中的第一和第二手柄。 该装置构造成在将活检针尖插入被取样的组织期间将第一针和第二针保持在第一位置。 该装置还被配置为分别以快速，自动化的顺序将第一针和第二针向前移动到随后的位置，以便分割和包围组织样本，其可以在从组织移除活检针系统之后进行测试。 组织样本检查特征允许在取出组织样本之后有助于相对于第二针的第一针的重新定位和维持，从而能够检查所检索的组织样本，而不从装置中移除任一针。 该装置进一步配置成可以从与装置壳体的前部或后部相邻的位置致动。