公开(公告)号：US09322784B2

公开(公告)日：2016-04-26

申请号：US13227761

申请日：2011-09-08

申请人： Josef Grassl ,  Gerald Probst ,  Markus Schürf

发明人： Josef Grassl ,  Gerald Probst ,  Markus Schürf

IPC分类号： C12Q1/02 ,  C12M1/34 ,  G01N21/00 ,  G01N21/17 ,  G01N21/64 ,  C12M1/04 ,  G01N21/25 ,  G01N33/50 ,  G01N35/02 ,  B01L9/00 ,  G01J3/12 ,  G01N35/00

CPC分类号： G01N35/028 ,  B01L9/52 ,  C12M1/04 ,  C12M41/14 ,  C12M41/16 ,  C12Q1/02 ,  G01J3/12 ,  G01N21/253 ,  G01N21/6452 ,  G01N33/5005 ,  G01N2035/00356 ,  G01N2201/023 ,  G01N2201/0231 ,  G01N2201/0238 ,  G01N2201/0446 ,  G01N2201/06113

摘要： A microplate reader and method has at least one measuring device and a holding device for accommodating at least one microplate and for positioning samples-containing wells of microplates in relation to the measuring device. The at least one measuring device is used for detecting light emitted by samples in wells of a microplate and/or which is influenced by samples transilluminated by light in the wells. The microplate reader has a control unit for controlling the composition of a gas atmosphere surrounding the wells containing the samples. A respective use is characterized particularly in that living cells are measured in a controlled gas atmosphere, wherein the living cells are chosen from microaerophilic, optionally anaerobic and obligatorily anaerobic microorganisms as well as fungi and eukaryotic cells.

摘要翻译： 微板读数器和方法具有至少一个测量装置和保持装置，用于容纳至少一个微孔板并且用于相对于测量装置定位含有微孔板的样品孔。 所述至少一个测量装置用于检测由微孔板的孔中的样品发射的光和/或受孔中由光透射的样品的影响。 微板读数器具有控制单元，用于控制包含样品的孔周围的气体气氛的组成。 各自的用途的特征在于，在受控气体气氛中测量活细胞，其中活细胞选自微需氧，任选的厌氧和强制性厌氧微生物以及真菌和真核细胞。

公开(公告)号：US08605279B2

公开(公告)日：2013-12-10

申请号：US12240099

申请日：2008-09-29

申请人： Walter Gotschy ,  Josef Grassl ,  Fritz Payr ,  Markus Schürf

发明人： Walter Gotschy ,  Josef Grassl ,  Fritz Payr ,  Markus Schürf

IPC分类号： G01N21/01

CPC分类号： G01N21/0303 ,  B01L3/5085 ,  B01L3/5088 ,  B01L2300/0654 ,  B01L2300/0829

摘要： Relates to a micro cuvette assembly (1), comprising a first partial plate (2) with one or more first cuvette surfaces (3) and a second partial plate (4) which is arrangeable relative to the first partial plate and has at least one or more second cuvette surfaces (5) which, in an active position of the micro cuvette assembly (1), are arranged in register plane-parallel to the first cuvette surfaces (3) and spaced apart by a distance (6), thus forming, in the active position of the micro cuvette assembly (1), one or more micro cuvettes (7) in which a liquid volume (8) applied previously to one of the cuvette surfaces (3,5) is held between these two cuvette surfaces (3,5). The micro cuvette assembly (1) according to the present invention is characterized in that each of the first cuvette surfaces (3) of the first partial plate (2) is formed individually and completely in each case by a surface of a transparent body (10) which is accomplished as a free beam optical element and arranged in each case in an opening (9) penetrating the first partial plate (2). Also disclosed is the use of this micro cuvette assembly (1) in the carrying-out of a method for examining biological samples.

摘要翻译： 与微量反应杯组件（1）相关，包括具有一个或多个第一反应杯表面（3）的第一部分板（2）和可相对于第一部分板布置的第二部分板（4），并且具有至少一个 或更多的第二试管表面（5），其在微量反应杯组件（1）的活动位置中被布置在与第一反应杯表面（3）平行并且间隔开距离（6）的对准平面中，从而形成 在微量比色杯组件（1）的活动位置中，将一个或多个微量比色杯（7）预先安装在其中一个比色皿表面（3,5）上的液体体积（8）保持在这两个比色皿表面之间 （3,5）。 根据本发明的微型反应杯组件（1）的特征在于，第一部分板（2）的每个第一反应杯表面（3）在每种情况下由透明体（10）的表面分别完全地形成 ），其实现为自由光束光学元件，并且在每种情况下布置在穿透第一部分板（2）的开口（9）中。 还公开了这种微量比色皿组件（1）在用于检查生物样品的方法的使用中的用途。

公开(公告)号：US08692988B2

公开(公告)日：2014-04-08

申请号：US13193149

申请日：2011-07-28

申请人： Walter Gotschy ,  Josef Grassel ,  Fritz Payr ,  Markus Schürf

发明人： Walter Gotschy ,  Josef Grassel ,  Fritz Payr ,  Markus Schürf

IPC分类号： G01N21/01

CPC分类号： G01N21/0303 ,  B01L3/5085 ,  B01L3/5088 ,  B01L2300/0654 ,  B01L2300/0829

摘要： Micro cuvette assembly for examining biological samples has a first partial plate with one or more first cuvette surfaces and a second partial plate opposite the first and which also has one or more second cuvette surfaces. In an active position of the assembly, the second cuvette surfaces are arranged parallel and in register with the first cuvette surfaces and are spaced apart from the first cuvette surfaces whereby one or more micro cuvettes are formed. The first and second partial plates also have openings arranged in register with the cuvette surfaces and transparent bodies are provided as the cuvette surfaces. The first and second plates are completely penetrated by these openings and the transparent bodies are manufactured from a different material than the partial plates and span the openings close to a first surface of the partial plates. The first and second cuvette surfaces of a micro cuvette in the active position are wetted by a liquid volume which has previously been applied to one of the cuvette surfaces so that the liquid volume is held between these two cuvette surfaces.

摘要翻译： 用于检查生物样品的微量比色皿组件具有第一部分板，其具有一个或多个第一反应杯表面和与第一部分相对的第二部分板，并且还具有一个或多个第二反应杯表面。 在组件的活动位置中，第二反应杯表面平行布置并与第一比色皿表面对准，并且与第一比色杯表面间隔开，由此形成一个或多个微量比色皿。 第一和第二部分板还具有与反应杯表面对准布置的开口，并且提供透明体作为比色皿表面。 第一和第二板被这些开口完全穿透，并且透明体由与局部板不同的材料制成，并且跨过部分板的第一表面附近的开口。 在活动位置的微量比色皿的第一和第二比色皿表面被预先施加到其中一个比色皿表面的液体体积润湿，使得液体体积保持在这两个比色皿表面之间。

公开(公告)号：US20120064564A1

公开(公告)日：2012-03-15

申请号：US13227761

申请日：2011-09-08

申请人： JOSEF GRASSL ,  Gerald Probst ,  Markus Schürf

发明人： JOSEF GRASSL ,  Gerald Probst ,  Markus Schürf

IPC分类号： C12Q1/02 ,  C12M1/34 ,  G01N21/17 ,  G01N21/00 ,  G01N21/64

CPC分类号： G01N35/028 ,  B01L9/52 ,  C12M1/04 ,  C12M41/14 ,  C12M41/16 ,  C12Q1/02 ,  G01J3/12 ,  G01N21/253 ,  G01N21/6452 ,  G01N33/5005 ,  G01N2035/00356 ,  G01N2201/023 ,  G01N2201/0231 ,  G01N2201/0238 ,  G01N2201/0446 ,  G01N2201/06113

摘要： A microplate reader and method has at least one measuring device and a holding device for accommodating at least one microplate and for positioning samples-containing wells of microplates in relation to the measuring device. The at least one measuring device is used for detecting light emitted by samples in wells of a microplate and/or which is influenced by samples transilluminated by light in the wells. The microplate reader has a control unit for controlling the composition of a gas atmosphere surrounding the wells containing the samples. A respective use is characterized particularly in that living cells are measured in a controlled gas atmosphere, wherein the living cells are chosen from microaerophilic, optionally anaerobic and obligatorily anaerobic microorganisms as well as fungi and eukaryotic cells.

摘要翻译： 微板读数器和方法具有至少一个测量装置和保持装置，用于容纳至少一个微孔板并且用于相对于测量装置定位含有微孔板的样品孔。 所述至少一个测量装置用于检测由微孔板的孔中的样品发射的光和/或受孔中由光透射的样品的影响。 微板读数器具有控制单元，用于控制包含样品的孔周围的气体气氛的组成。 各自的用途的特征在于，在受控气体气氛中测量活细胞，其中活细胞选自微需氧，任选的厌氧和强制性厌氧微生物以及真菌和真核细胞。

公开(公告)号：US20110292383A1

公开(公告)日：2011-12-01

申请号：US13193149

申请日：2011-07-28

申请人： Walter Gotschy ,  Josef Grassl ,  Fritz Payr ,  Markus Schürf

发明人： Walter Gotschy ,  Josef Grassl ,  Fritz Payr ,  Markus Schürf

IPC分类号： G01N21/03

CPC分类号： G01N21/0303 ,  B01L3/5085 ,  B01L3/5088 ,  B01L2300/0654 ,  B01L2300/0829

摘要： Micro cuvette assembly for examining biological samples has a first partial plate with one or more first cuvette surfaces and a second partial plate opposite the first and which also has one or more second cuvette surfaces. In an active position of the assembly, the second cuvette surfaces are arranged parallel and in register with the first cuvette surfaces and are spaced apart from the first cuvette surfaces whereby one or more micro cuvettes are formed. The first and second partial plates also have openings arranged in register with the cuvette surfaces and transparent bodies are provided as the cuvette surfaces. The first and second plates are completely penetrated by these openings and the transparent bodies are manufactured from a different material than the partial plates and span the openings close to a first surface of the partial plates. The first and second cuvette surfaces of a micro cuvette in the active position are wetted by a liquid volume which has previously been applied to one of the cuvette surfaces so that the liquid volume is held between these two cuvette surfaces.

摘要翻译： 用于检查生物样品的微量比色皿组件具有第一部分板，其具有一个或多个第一反应杯表面和与第一部分相对的第二部分板，并且还具有一个或多个第二反应杯表面。 在组件的活动位置中，第二反应杯表面平行布置并与第一比色皿表面对准，并且与第一比色杯表面间隔开，由此形成一个或多个微量比色皿。 第一和第二部分板还具有与反应杯表面对准布置的开口，并且提供透明体作为比色皿表面。 第一和第二板被这些开口完全穿透，并且透明体由与局部板不同的材料制成，并且跨过部分板的第一表面附近的开口。 在活动位置的微量比色皿的第一和第二比色皿表面被预先施加到其中一个比色皿表面的液体体积润湿，使得液体体积保持在这两个比色皿表面之间。