公开(公告)号：US08365608B2

公开(公告)日：2013-02-05

申请号：US12726790

申请日：2010-03-18

申请人： Masatoshi Iida

发明人： Masatoshi Iida

IPC分类号： G01B5/30 ,  G01N3/08

CPC分类号： B25J9/1045 ,  B25J18/06 ,  Y10T74/20323 ,  Y10T74/20329

摘要： A tension detection mechanism includes a linear member which extends in a longitudinal direction, and which is configured to transmits power, a restraining member including a restraining portion through which the linear member extends and which is configured to restrain movement of the linear member in the longitudinal direction partially, and a detection member which is provided to the restraining member and which is configured to detect tension of the linear member. A length of a portion of the linear member restrained by the restraining portion is larger than a distance between two ends of the restraining member in the longitudinal direction of the linear member.

摘要翻译： 张力检测机构包括沿长度方向延伸并且被构造成传递动力的线性构件，包括限制部分的限制构件，所述限制构件包括限制部分，所述线性构件延伸通过所述限制部分，并且构造成限制所述线性构件在纵向方向上的运动 以及检测部件，其设置在所述限制部件上并被构造成检测所述直线部件的张力。 由限制部限制的直线部件的一部分的长度大于限制部件在线状部件的长度方向的两端之间的距离。

公开(公告)号：US20090117798A1

公开(公告)日：2009-05-07

申请号：US11666658

申请日：2005-10-20

申请人： Seisuke Takashima ,  Masatoshi Iida

发明人： Seisuke Takashima ,  Masatoshi Iida

IPC分类号： D06M11/46

CPC分类号： A61L9/18 ,  A61L9/16 ,  B01D39/1615 ,  B01D39/1623 ,  B01D39/18 ,  B01D2239/0216 ,  B01D2239/0442 ,  B01D2239/0471 ,  D03D15/00 ,  D06M11/46 ,  D06M15/333 ,  D06M16/00 ,  D10B2201/02 ,  D10B2331/02 ,  D10B2331/04 ,  D10B2401/13 ,  D10B2503/04 ,  D10B2505/04 ,  D10B2505/10 ,  D21H13/14 ,  D21H17/09 ,  D21H17/14 ,  D21H19/38 ,  D21H21/36 ,  Y10T428/31855 ,  Y10T442/2082 ,  Y10T442/2525 ,  Y10T442/2861 ,  Y10T442/2877

摘要： A sheet made of a fabric or paper coated with a substance which has a strong function to adsorb, remove and make harmless microbes such as bacteria and viruses is to be configured so as to be usable as a filter, a mask or the like capable of removing the microbes such as the bacteria and viruses.A sheet made of a fabric which uses a fibrous material, for example, polyester in which a sulfenate group or a carboxylate group has been introduced, and has a surface coated, for example, with anatase type titanium oxide makes microbes such as bacteria and viruses harmless by adsorbing these microbes and has sufficient air permeability, therefore being usable as a filter, a mask or the like. Furthermore, a sheet made of a fabric or paper which is impregnated with an aqueous solution of polyvinyl alcohol copolymerized with a monomer having a sulfonate group or carboxylate group as a fabric size and on which titanium oxide is coated and fixed has a function to make harmful microbes harmless by adsorbing these microbes, therefore being usable not only as a filter or a mask but also as fruit packing material or the like.

摘要翻译： 由具有吸附，去除和使细菌和病毒等微生物无害的强力功能的物质的织物或纸张制成的片材被配置为可用作能够用作过滤器，掩模等的物品 去除细菌和病毒等微生物。 使用纤维材料的织物制成的片材，例如已经引入了次磺酸酯基或羧酸酯基团的聚酯，并且具有例如用锐钛矿型氧化钛的表面涂覆，使细菌和病毒等微生物 通过吸附这些微生物而无害，并具有足够的透气性，因此可用作过滤器，掩模等。 此外，将由与磺酸酯基或羧酸酯基的单体共聚的聚乙烯醇的水溶液浸渍的织物或纸制成的片材作为织物尺寸，并且其上涂覆和固定氧化钛的功能是使有害的 微生物通过吸附这些微生物而无害化，因此不仅可用作过滤器或面罩，而且可用作水果包装材料等。

公开(公告)号：US08551999B2

公开(公告)日：2013-10-08

申请号：US12740684

申请日：2008-10-29

申请人： Takumi Sumida ,  Fujio Tabusa ,  Kazuo Sekiguchi ,  Takeshi Kodama ,  Koichi Yasumura ,  Yutaka Kojima ,  Masaaki Motoyama ,  Keisuke Miyajima ,  Kenji Yoshida ,  Keizo Kan ,  Makoto Sakamoto ,  Hideki Takasu ,  Takashi Nakagawa ,  Naoto Ohi ,  Yasuo Harada ,  Norikazu Hashimoto ,  Hironori Matsuyama ,  Masatoshi Iida ,  Shigekazu Fujita ,  Tae Fukushima

发明人： Takumi Sumida ,  Fujio Tabusa ,  Kazuo Sekiguchi ,  Takeshi Kodama ,  Koichi Yasumura ,  Yutaka Kojima ,  Masaaki Motoyama ,  Keisuke Miyajima ,  Kenji Yoshida ,  Keizo Kan ,  Makoto Sakamoto ,  Hideki Takasu ,  Takashi Nakagawa ,  Naoto Ohi ,  Yasuo Harada ,  Norikazu Hashimoto ,  Hironori Matsuyama ,  Masatoshi Iida ,  Shigekazu Fujita ,  Tae Fukushima

IPC分类号： A61K31/496 ,  A61K31/454 ,  C07D401/12 ,  C07D401/14 ,  C07D405/14 ,  C07D417/14 ,  A61K31/506 ,  C07D403/12

CPC分类号： C07D401/12 ,  C07D403/12

摘要： The present invention provides a heterocyclic compound represented by General Formula (1): wherein R1 is a group R5—Z1—, etc., Z1 is a lower alkylene group, etc., and R5 is a group represented by General Formula; wherein R13 is a hydrogen atom, etc., m is an integer from 1 to 5; R2 is a hydrogen atom: Y is CH or N: A1 is a heterocyclic ring selected from the group consisting of indolediyl groups, wherein the heterocyclic ring may have at least one substituent: T is a group —CO—, etc.: R3 is a hydrogen atom, etc.: R4 is a lower alkyl group optionally substituted by one or more hydroxy groups, etc.: R3 and R4, together with the nitrogen atom to which they bind, may bind to each other and form a 5- to 10-membered saturated heterocyclic ring, wherein the heterocyclic ring may have at least one substituent. The heterocyclic compound of the present invention has excellent effects of suppressing the production of collagen and/or treating tumors.

摘要翻译： 本发明提供由通式（1）表示的杂环化合物：其中R1为R5-Z1-基团等，Z1为低级亚烷基等，R5为通式所示的基团。 其中R 13为氢原子等，m为1至5的整数; R2是氢原子：Y是CH或N：A1是选自吲哚二基的杂环，其中杂环可以具有至少一个取代基：T是-CO-等：R3是 氢原子等：R4是任选被一个或多个羟基取代的低级烷基等：R 3和R 4与它们所键合的氮原子一起可以彼此结合形成5- 10元饱和杂环，其中杂环可以具有至少一个取代基。 本发明的杂环化合物具有抑制胶原蛋白的生成和/或治疗肿瘤的优异效果。

公开(公告)号：US20100236352A1

公开(公告)日：2010-09-23

申请号：US12726790

申请日：2010-03-18

申请人： Masatoshi IIDA

发明人： Masatoshi IIDA

IPC分类号： B25J18/00 ,  B25J17/00 ,  B25J18/06

CPC分类号： B25J9/1045 ,  B25J18/06 ,  Y10T74/20323 ,  Y10T74/20329

摘要： A tension detection mechanism includes a linear member which extends in a longitudinal direction, and which is configured to transmits power, a restraining member including a restraining portion through which the linear member extends and which is configured to restrain movement of the linear member in the longitudinal direction partially, and a detection member which is provided to the restraining member and which is configured to detect tension of the linear member. A length of a portion of the linear member restrained by the restraining portion is larger than a distance between two ends of the restraining member in the longitudinal direction of the linear member.

摘要翻译： 张力检测机构包括沿长度方向延伸并且被构造成传递动力的线性构件，包括限制部分的限制构件，所述限制构件包括限制部分，所述线性构件延伸通过所述限制部分，并且构造成限制所述线性构件在纵向方向上的运动 以及检测部件，其设置在所述限制部件上并被构造成检测所述直线部件的张力。 由限制部限制的直线部件的一部分的长度大于限制部件在线状部件的长度方向的两端之间的距离。

公开(公告)号：US08647330B2

公开(公告)日：2014-02-11

申请号：US12726671

申请日：2010-03-18

申请人： Masatoshi Iida

发明人： Masatoshi Iida

IPC分类号： A61B17/00

CPC分类号： A61B34/30 ,  A61B34/71 ,  A61B2034/305

摘要： A manipulator joint displacement detection mechanism includes a manipulator which has a actuating unit and a joint. A first transmission member is connected to the joint, and provided movably to displace the joint. A second transmission member moves corresponding to movement of the first transmission member. A guide guides movement of the second transmission member. A guide fixing part fixes one end and the other end of the guide. A sensor detects a moving distance of the second transmission member in the proximal end portion of the manipulator.

摘要翻译： 机械手关节位移检测机构包括具有致动单元和接头的操纵器。 第一传动构件连接到接头，并且可移动地设置以使接头移位。 第二传动构件相应于第一传动构件的运动而移动。 引导件引导第二传动件的运动。 引导固定部分固定引导件的一端和另一端。 传感器检测第二传动部件在机械手的近端部的移动距离。

公开(公告)号：US08227360B2

公开(公告)日：2012-07-24

申请号：US11666658

申请日：2005-10-20

申请人： Seisuke Takashima ,  Masatoshi Iida

发明人： Seisuke Takashima ,  Masatoshi Iida

IPC分类号： B32B27/14

CPC分类号： A61L9/18 ,  A61L9/16 ,  B01D39/1615 ,  B01D39/1623 ,  B01D39/18 ,  B01D2239/0216 ,  B01D2239/0442 ,  B01D2239/0471 ,  D03D15/00 ,  D06M11/46 ,  D06M15/333 ,  D06M16/00 ,  D10B2201/02 ,  D10B2331/02 ,  D10B2331/04 ,  D10B2401/13 ,  D10B2503/04 ,  D10B2505/04 ,  D10B2505/10 ,  D21H13/14 ,  D21H17/09 ,  D21H17/14 ,  D21H19/38 ,  D21H21/36 ,  Y10T428/31855 ,  Y10T442/2082 ,  Y10T442/2525 ,  Y10T442/2861 ,  Y10T442/2877

摘要： [Problem to be Solved]A sheet made of a fabric or paper coated with a substance which has a strong function to adsorb, remove and make harmless microbes such as bacteria and viruses is to be configured so as to be usable as a filter, a mask or the like capable of removing the microbes such as the bacteria and viruses.[Solving Means]A sheet made of a fabric which uses a fibrous material, for example, polyester in which a sulfenate group or a carboxylate group has been introduced, and has a surface coated, for example, with anatase type titanium oxide makes microbes such as bacteria and viruses harmless by adsorbing these microbes and has sufficient air permeability, therefore being usable as a filter, a mask or the like. Furthermore, a sheet made of a fabric or paper which is impregnated with an aqueous solution of polyvinyl alcohol copolymerized with a monomer having a sulfonate group or carboxylate group as a fabric size and on which titanium oxide is coated and fixed has a function to make harmful microbes harmless by adsorbing these microbes, therefore being usable not only as a filter or a mask but also as fruit packing material or the like.

摘要翻译： [待解决的问题]将具有吸附，去除和使细菌，病毒等微生物无害化的功能的物质涂布在织物或纸上的片材构成为能够用作过滤器， 能够除去微生物如细菌和病毒的面具等。 [解决方案]使用纤维材料的织物制成的片材，例如已经导入次硫酸盐基或羧酸盐基团的聚酯，并且具有例如用锐钛矿型氧化钛的表面涂覆使得微生物 因为细菌和病毒通过吸附这些微生物而无害，并且具有足够的透气性，因此可用作过滤器，面罩等。 此外，将由与磺酸酯基或羧酸酯基的单体共聚的聚乙烯醇的水溶液浸渍的织物或纸制成的片材作为织物尺寸，并且其上涂覆和固定氧化钛的功能是使有害的 微生物通过吸附这些微生物而无害化，因此不仅可用作过滤器或面罩，而且可用作水果包装材料等。

公开(公告)号：US20100241135A1

公开(公告)日：2010-09-23

申请号：US12726671

申请日：2010-03-18

申请人： Masatoshi IIDA

发明人： Masatoshi IIDA

IPC分类号： A61B19/00

CPC分类号： A61B34/30 ,  A61B34/71 ,  A61B2034/305

摘要： A manipulator joint displacement detection mechanism includes a manipulator which has a actuating unit and a joint. A first transmission member is connected to the joint, and provided movably to displace the joint. A second transmission member moves corresponding to movement of the first transmission member. A guide guides movement of the second transmission member. A guide fixing part fixes one end and the other end of the guide. A sensor detects a moving distance of the second transmission member in the proximal end portion of the manipulator.

摘要翻译： 机械手关节位移检测机构包括具有致动单元和接头的操纵器。 第一传动构件连接到接头，并且可移动地设置以使接头移位。 第二传动构件相应于第一传动构件的运动而移动。 引导件引导第二传动件的运动。 引导固定部分固定引导件的一端和另一端。 传感器检测第二传动部件在机械手的近端部的移动距离。

公开(公告)号：US20100261720A1

公开(公告)日：2010-10-14

申请号：US12740684

申请日：2008-10-29

申请人： Takumi Sumida ,  Fujio Tabusa ,  Kazuo Sekiguchi ,  Takeshi Kodama ,  Koichi Yasumura ,  Yutaka Kojima ,  Masaaki Motoyama ,  Keisuke Miyajima ,  Kenji Yoshida ,  Keizo Kan ,  Makoto Sakamoto ,  Hideki Takasu ,  Takashi Nakagawa ,  Naoto Ohi ,  Yasuo Harada ,  Norikazu Hashimoto ,  Hironori Matsuyama ,  Masatoshi Iida ,  Shigekazu Fujita ,  Tae Fukushima

发明人： Takumi Sumida ,  Fujio Tabusa ,  Kazuo Sekiguchi ,  Takeshi Kodama ,  Koichi Yasumura ,  Yutaka Kojima ,  Masaaki Motoyama ,  Keisuke Miyajima ,  Kenji Yoshida ,  Keizo Kan ,  Makoto Sakamoto ,  Hideki Takasu ,  Takashi Nakagawa ,  Naoto Ohi ,  Yasuo Harada ,  Norikazu Hashimoto ,  Hironori Matsuyama ,  Masatoshi Iida ,  Shigekazu Fujita ,  Tae Fukushima

IPC分类号： A61K31/5377 ,  C07D401/14 ,  C07D413/14 ,  A61K31/497 ,  C07D403/14 ,  A61P35/00 ,  A61P43/00

CPC分类号： C07D401/12 ,  C07D403/12

摘要： The present invention provides a heterocyclic compound represented by General Formula (1): wherein R1 is a group R5—Z1—, etc., Z1 is a lower alkylene group, etc., and R5 is a group represented by General Formula; wherein R13 is a hydrogen atom, etc., m is an integer from 1 to 5; R2 is a hydrogen atom: Y is CH or N: A1 is a heterocyclic ring selected from the group consisting of indolediyl groups, wherein the heterocyclic ring may have at least one substituent: T is a group —CO—, etc.: R3 is a hydrogen atom, etc.: R4 is a lower alkyl group optionally substituted by one or more hydroxy groups, etc.: R3 and R4, together with the nitrogen atom to which they bind, may bind to each other and form a 5- to 10-membered saturated heterocyclic ring, wherein the heterocyclic ring may have at least one substituent. The heterocyclic compound of the present invention has excellent effects of suppressing the production of collagen and/or treating tumors.

摘要翻译： 本发明提供由通式（1）表示的杂环化合物：其中R1为R5-Z1-基团等，Z1为低级亚烷基等，R5为通式所示的基团。 其中R 13为氢原子等，m为1至5的整数; R2是氢原子：Y是CH或N：A1是选自吲哚二基的杂环，其中杂环可以具有至少一个取代基：T是-CO-等：R3是 氢原子等：R4是任选被一个或多个羟基取代的低级烷基等：R 3和R 4与它们所键合的氮原子一起可以彼此结合形成5- 10元饱和杂环，其中杂环可以具有至少一个取代基。 本发明的杂环化合物具有抑制胶原蛋白的生成和/或治疗肿瘤的优异效果。

公开(公告)号：US07291266B2

公开(公告)日：2007-11-06

申请号：US10499037

申请日：2002-12-18

申请人： Seisuke Takashima ,  Ryousuke Murayama ,  Masatoshi Iida ,  Masayoshi Furuhashi

发明人： Seisuke Takashima ,  Ryousuke Murayama ,  Masatoshi Iida ,  Masayoshi Furuhashi

IPC分类号： C02F1/42 ,  C02F9/00 ,  C02F9/02 ,  C02F9/08 ,  C02F9/12

CPC分类号： C02F1/28 ,  B01D39/1623 ,  B01D39/2017 ,  B01D39/2058 ,  B01D2239/0407 ,  B01D2239/0442 ,  B01D2239/045 ,  B01D2239/0618 ,  B01D2239/065 ,  B01J20/20 ,  B01J20/28052 ,  B01J47/026 ,  C02F1/001 ,  C02F1/02 ,  C02F1/281 ,  C02F1/283 ,  C02F1/32 ,  C02F1/42 ,  C02F1/52 ,  C02F9/00 ,  C02F2001/425 ,  C02F2103/04 ,  C02F2201/006 ,  C02F2201/326

摘要： To compose a composite filter for obtaining water having a high purity usable as water for life and water for medicine from water in which impurities are mixed. Furthermore, to compose an apparatus for obtaining water having a high purity using the filter. Moreover, to configure the apparatus so as to facilitate exchange of the filter. That is, water having a high purity can be obtained by allowing raw water to permeate through a composite filter which consists of a first layer 11 made of fibers, a second layer 12 made of ion exchange resin, a third layer 14 made of activated carbon and a fourth layer 16 made of an unwoven textile. These first layer, second layer, third layer and fourth layer are configured as separate independent filters respectively so that each filter can be exchanged independently. Furthermore, different kinds of filters can be combined dependently on purposes of use.

摘要翻译： 组合复合过滤器，用于获得可用作生命之水的高纯度水和用于混合杂质的水中的医药用水。 此外，构成使用过滤器获得高纯度的水的装置。 此外，为了配置该装置以便于滤波器的更换。 也就是说，可以通过使原水透过由纤维制成的第一层11，由离子交换树脂制成的第二层12，由活性炭制成的第三层14组成的复合过滤器来获得高纯度的水 以及由无纺织物制成的第四层16。 这些第一层，第二层，第三层和第四层分别被配置为独立的独立滤波器，使得可以独立地交换每个滤波器。 此外，不同种类的过滤器可以根据使用目的进行组合。

公开(公告)号：US20050023223A1

公开(公告)日：2005-02-03

申请号：US10499037

申请日：2002-12-18

申请人： Seisuke Takashima ,  Ryousuke Murayama ,  Masatoshi Iida ,  Masayoshi Furuhashi

发明人： Seisuke Takashima ,  Ryousuke Murayama ,  Masatoshi Iida ,  Masayoshi Furuhashi

IPC分类号： B01D15/00 ,  B01D39/16 ,  B01D39/20 ,  B01J47/02 ,  C02F1/02 ,  C02F1/28 ,  C02F1/32 ,  C02F1/42 ,  C02F1/52 ,  C02F9/00

CPC分类号： C02F1/28 ,  B01D39/1623 ,  B01D39/2017 ,  B01D39/2058 ,  B01D2239/0407 ,  B01D2239/0442 ,  B01D2239/045 ,  B01D2239/0618 ,  B01D2239/065 ,  B01J20/20 ,  B01J20/28052 ,  B01J47/026 ,  C02F1/001 ,  C02F1/02 ,  C02F1/281 ,  C02F1/283 ,  C02F1/32 ,  C02F1/42 ,  C02F1/52 ,  C02F9/00 ,  C02F2001/425 ,  C02F2103/04 ,  C02F2201/006 ,  C02F2201/326

摘要： To compose a composite filter for obtaining water having a high purity usable as water for life and water for medicine from water in which impurities are mixed. Furthermore, to compose an apparatus for obtaining water having a high purity using the filter. Moreover, to configure the apparatus so as to facilitate exchange of the filter. That is, water having a high purity can be obtained by allowing raw water to permeate through a composite filter which consists of a first layer 11 made of fibers, a second layer 12 made of ion exchange resin, a third layer 14 made of activated carbon and a fourth layer 16 made of an unwoven textile. These first layer, second layer, third layer and fourth layer are configured as separate independent filters respectively so that each filter can be exchanged independently. Furthermore, different kinds of filters can be combined dependently on purposes of use.

摘要翻译： 组合复合过滤器，用于获得可用作生命之水的高纯度水和用于混合杂质的水中的医药用水。 此外，构成使用过滤器获得高纯度的水的装置。 此外，为了配置该装置以便于滤波器的更换。 也就是说，可以通过使原水透过由纤维制成的第一层11，由离子交换树脂制成的第二层12，由活性炭制成的第三层14组成的复合过滤器来获得高纯度的水 以及由无纺织物制成的第四层16。 这些第一层，第二层，第三层和第四层分别被配置为独立的独立滤波器，使得可以独立地交换每个滤波器。 此外，不同种类的过滤器可以根据使用目的进行组合。