Abstract:
The present invention relates to novel compounds of formulae (I) and (II) and pharmaceutically acceptable salts thereof that are useful in the treatment and/or prevention of human and animal bacterial infections and associated diseases and conditions; compositions containing such compounds; derivation of such compounds by fermentation and isolation, partial synthesis and total synthesis; methods of inhibiting bacterial growth; methods of treating, preventing or controlling bacterial infection; biologically pure cultures of bacterial strains from which such compounds may be produced; and processes for preparing compositions containing such compounds.
Abstract:
The present invention relates to novel compounds of formulae (I) and (II) and pharmaceutically acceptable salts thereof that are useful in the treatment and/or prevention of human and animal bacterial infections and associated diseases and conditions; compositions containing such compounds; derivation of such compounds by fermentation and isolation, partial synthesis and total synthesis; methods of inhibiting bacterial growth; methods of treating, preventing or controlling bacterial infection; biologically pure cultures of bacterial strains from which such compounds may be produced; and processes for preparing compositions containing such compounds.
Abstract:
A method and system generate a workflow for the production of a three-dimensional document. A knowledge base contains production rules for several dimensional documents. The production rules relate to a plurality of jobs, i.e., units of work involved in the production of a dimensional document. The rules also identify human and/or mechanical resources required to complete each job. The system receives, from multiple service providers, capability information corresponding to each service provider's available resources. The capability information is associated with the production rules and stored in the knowledge base. When a user selects a dimensional document to be produced, the system selects appropriate production rules for the document, accesses the associated capability information, and automatically generates a workflow for the document. The system distributes various jobs in the workflow among at least two different service providers.
Abstract:
A system for creating variable dimension digital documents. The system includes a computer processor and a computer readable medium operably connected to the computer processor and having at least one software module installed on the computer readable medium and containing instructions for operating the computer processor to perform a process. The process includes the steps of receiving a user defined goal for creating a variable dimension digital document, wherein the user defined goal includes at least one recipient, determining at least one document template based upon the user defined goal, determining a plurality of digital assets to include in the variable dimension digital document based upon the document template and the user defined goal, creating a plurality of data files representing the potential variable dimension digital documents, and producing a results set including the potential variable dimension digital documents.
Abstract:
This invention relates to the use of potent potassium channel blockers or a formulation thereof in the treatment of glaucoma and other conditions related to elevated intraocular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of a mammalian species, particularly humans.
Abstract:
A method and system generate a workflow for the production of a three-dimensional document. A knowledge base contains production rules for several dimensional documents. The production rules relate to a plurality of jobs, i.e., units of work involved in the production of a dimensional document. The rules also identify human and/or mechanical resources required to complete each job. The system receives, from multiple service providers, capability information corresponding to each service provider's available resources. The capability information is associated with the production rules and stored in the knowledge base. When a user selects a dimensional document to be produced, the system selects appropriate production rules for the document, accesses the associated capability information, and automatically generates a workflow for the document. The system distributes various jobs in the workflow among at least two different service providers.
Abstract:
This invention relates to the use of potent potassium channel blockers or a formulation thereof in the treatment of glaucoma and other conditions related to elevated intraocular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of a mammalian species, particularly humans.