-
公开(公告)号：US5770587A
公开(公告)日：1998-06-23
申请号：US734701
申请日：1996-10-21
申请人： Angela Basilio , Fernando Pelaez , Maria Teresa Diez , Francisca Vicente , Sandra A. Morris , James E. Curotto , Gerald F. Bills , Sarah J. Dreikorn , Otto D. Hensens , Jerrold M. Liesch , Rosalind G. Jenkins , John R. Thompson
发明人： Angela Basilio , Fernando Pelaez , Maria Teresa Diez , Francisca Vicente , Sandra A. Morris , James E. Curotto , Gerald F. Bills , Sarah J. Dreikorn , Otto D. Hensens , Jerrold M. Liesch , Rosalind G. Jenkins , John R. Thompson
CPC分类号： C07J63/008
摘要： There are disclosed novel compounds having the formula ##STR1## which exhibit antifungal activity.
-
公开(公告)号：US5543431A
公开(公告)日：1996-08-06
申请号：US449622
申请日：1995-05-24
申请人： Evon A. Bolessa , Robert E. Schwartz , Gerald F. Bills , Robert A. Giacobbe , Fernando Pelaez Perez , Angeles Cabello Arroyo , Teresa Diez Matas , Isabel Martin Fernandez , Francisca Vicente Perez , Suzanne M. Mandala , Deborah L. Zink , Rosemary Thornton , John R. Thompson , James E. Curotto
发明人： Evon A. Bolessa , Robert E. Schwartz , Gerald F. Bills , Robert A. Giacobbe , Fernando Pelaez Perez , Angeles Cabello Arroyo , Teresa Diez Matas , Isabel Martin Fernandez , Francisca Vicente Perez , Suzanne M. Mandala , Deborah L. Zink , Rosemary Thornton , John R. Thompson , James E. Curotto
IPC分类号： C07D207/12 , C07C233/09 , A61K31/16 , A61K31/695 , C07C233/20
CPC分类号： C07D207/12
摘要： A compound having the formula ##STR1## which is an anti-fungal agent is described. The producing organism Colletotricum accutatum is also described, along with a method of production.
-
公开(公告)号：US09126983B2
公开(公告)日：2015-09-08
申请号：US13518613
申请日：2010-12-17
申请人： Sheo Singh , Jon D. Polishook , Deborah L. Zink , Olga Genilloud , Michael Goetz , Francisca Vicente , David Brian Olsen , Scott Knoble Smith
发明人： Sheo Singh , Jon D. Polishook , Deborah L. Zink , Olga Genilloud , Michael Goetz , Francisca Vicente , David Brian Olsen , Scott Knoble Smith
IPC分类号： C07H15/26 , A61P31/04 , A61K31/706 , A61K31/7056 , A01N43/86 , A01N43/36 , C07D407/14 , A61K31/535 , A61K31/4025 , C07D413/14 , C12P17/16 , C12R1/01
CPC分类号： C07D407/14 , A01N43/36 , A01N43/86 , A61K31/4025 , A61K31/535 , C07D413/14 , C12P17/16 , C12R1/01 , Y02A50/473
摘要： The present invention relates to novel compounds of formulae (I) and (II) and pharmaceutically acceptable salts thereof that are useful in the treatment and/or prevention of human and animal bacterial infections and associated diseases and conditions; compositions containing such compounds; derivation of such compounds by fermentation and isolation, partial synthesis and total synthesis; methods of inhibiting bacterial growth; methods of treating, preventing or controlling bacterial infection; biologically pure cultures of bacterial strains from which such compounds may be produced; and processes for preparing compositions containing such compounds.
摘要翻译： 本发明涉及可用于治疗和/或预防人和动物细菌感染和相关疾病和病症的式（I）和（II）的新化合物及其药学上可接受的盐; 含有这些化合物的组合物; 通过发酵和分离，部分合成和总合成衍生这些化合物; 抑制细菌生长的方法 治疗，预防或控制细菌感染的方法; 细菌菌株的生物纯培养物可从其中产生这些化合物; 以及制备含有这些化合物的组合物的方法。
-
公开(公告)号：US20130005673A1
公开(公告)日：2013-01-03
申请号：US13518613
申请日：2010-12-17
申请人： Sheo Singh , Jon D. Polishook , Deborah L. Zink , Olga Genilloud , Michael Goetz , Francisca Vicente , David Brian Olsen , Scott Knoble Smith
发明人： Sheo Singh , Jon D. Polishook , Deborah L. Zink , Olga Genilloud , Michael Goetz , Francisca Vicente , David Brian Olsen , Scott Knoble Smith
IPC分类号： C07H15/26 , C12P19/46 , A61P31/04 , C12N1/20 , A61K31/706 , A61K31/7056
CPC分类号： C07D407/14 , A01N43/36 , A01N43/86 , A61K31/4025 , A61K31/535 , C07D413/14 , C12P17/16 , C12R1/01 , Y02A50/473
摘要： The present invention relates to novel compounds of formulae (I) and (II) and pharmaceutically acceptable salts thereof that are useful in the treatment and/or prevention of human and animal bacterial infections and associated diseases and conditions; compositions containing such compounds; derivation of such compounds by fermentation and isolation, partial synthesis and total synthesis; methods of inhibiting bacterial growth; methods of treating, preventing or controlling bacterial infection; biologically pure cultures of bacterial strains from which such compounds may be produced; and processes for preparing compositions containing such compounds.
摘要翻译： 本发明涉及可用于治疗和/或预防人和动物细菌感染和相关疾病和病症的式（I）和（II）的新化合物及其药学上可接受的盐; 含有这些化合物的组合物; 通过发酵和分离，部分合成和总合成衍生这些化合物; 抑制细菌生长的方法 治疗，预防或控制细菌感染的方法; 细菌菌株的生物纯培养物可从其中产生这些化合物; 以及制备含有这些化合物的组合物的方法。
-
5.发明授权Antifungal agent produced by arthrinium arundinis ATCC 74359 失效由arthrinium arundinis ATCC 74359生产的抗真菌剂
公开(公告)号：US5712109A
公开(公告)日：1998-01-27
申请号：US789348
申请日：1997-01-27
申请人： Jerrold M. Liesch , Maria S. Meinz , Janet C. Onishi , Robert E. Schwartz , Gerald F. Bills , Robert A. Giacobbe , Deborah L. Zink , Angeles Cabello , Maria T. Diez , Isabella Martin , Fernando Pelaez , Francisca Vicente
发明人： Jerrold M. Liesch , Maria S. Meinz , Janet C. Onishi , Robert E. Schwartz , Gerald F. Bills , Robert A. Giacobbe , Deborah L. Zink , Angeles Cabello , Maria T. Diez , Isabella Martin , Fernando Pelaez , Francisca Vicente
CPC分类号： C07J9/00
摘要： There is disclosed a compound having the formula ##STR1## which is produced by the fungus, Arthrinium arundinis ATCC 74359, and exhibits antifungal activity.
摘要翻译： 公开了由真菌Arthrinium arundinis ATCC 74359产生的具有式（I）的化合物，并表现出抗真菌活性。
-
公开(公告)号：US5348970A
公开(公告)日：1994-09-20
申请号：US125432
申请日：1993-09-22
申请人： Robert E. Schwartz , Janet C. Onishi , Gerald F. Bills , Robert A. Giacobbe , Fernando Pelaez , Maria T. Diez , Francisca Vicente , Julian Gorrochategui , Gregory L. Helms , Barnali Pramanik
发明人： Robert E. Schwartz , Janet C. Onishi , Gerald F. Bills , Robert A. Giacobbe , Fernando Pelaez , Maria T. Diez , Francisca Vicente , Julian Gorrochategui , Gregory L. Helms , Barnali Pramanik
IPC分类号： C07D405/06 , A61K31/40
CPC分类号： C07D405/06
摘要： A compound of the formula 1: ##STR1## is produced via fermentation of a fungal isolate ATCC no. 74235. The organism is included herein, as well as a process for production of the compound, a pharmaceutical composition and a method of treatment.
摘要翻译： 通过真菌分离物ATCC号的发酵产生式1化合物：
1。 生物体包括在本文中，以及生产化合物的方法，药物组合物和治疗方法。 -
公开(公告)号：US5756472A
公开(公告)日：1998-05-26
申请号：US789349
申请日：1997-01-27
申请人： Jerrold M. Liesch , Maria S. Meinz , Janet C. Onishi , Sandra A. Morris , Robert E. Schwartz , Gerald F. Bills , Robert A. Giacobbe , Wendy S. Horn , Deborah L. Zink , Angeles Cabello , Maria T. Diez , Isabella Martin , Fernando Pelaez , Francisca Vicente
发明人： Jerrold M. Liesch , Maria S. Meinz , Janet C. Onishi , Sandra A. Morris , Robert E. Schwartz , Gerald F. Bills , Robert A. Giacobbe , Wendy S. Horn , Deborah L. Zink , Angeles Cabello , Maria T. Diez , Isabella Martin , Fernando Pelaez , Francisca Vicente
IPC分类号： C07H15/24 , A61K31/70 , C07D315/00 , C12N1/14
CPC分类号： C07H15/24 , Y10S435/911
摘要： There is disclosed a novel compound having the formula ##STR1## which exhibits antifungal activity.
摘要翻译： 公开了具有抗真菌活性的具有式（I）＆lt; IMAGE＆gt;的式的新化合物。
-
公开(公告)号：US5712151A
公开(公告)日：1998-01-27
申请号：US734702
申请日：1996-10-21
申请人： Sandra A. Morris , Gerald F. Bills , James E. Curotto , Sarah J. Dreikorn , Angela Basilio , Maria Teresa Diez , Fernando Pelaez , Francisca Vicente , Bruce W. Burgess , Stanley L. Streicher , Deborah L. Zink , John R. Thompson
发明人： Sandra A. Morris , Gerald F. Bills , James E. Curotto , Sarah J. Dreikorn , Angela Basilio , Maria Teresa Diez , Fernando Pelaez , Francisca Vicente , Bruce W. Burgess , Stanley L. Streicher , Deborah L. Zink , John R. Thompson
IPC分类号： A01N37/42 , C07D207/44 , C07D207/448 , C12P17/10 , C12N5/00 , C12N5/02
CPC分类号： C07D207/448 , A01N37/42 , C12P17/10 , C12R1/645
摘要： There is disclosed a novel compound having the formula ##STR1## which exhibits antifungal activity.
摘要翻译： 公开了具有抗真菌活性的具有式（I）的化合物。
-
公开(公告)号：US5233062A
公开(公告)日：1993-08-03
申请号：US851594
申请日：1992-03-16
申请人： Wendy S. Horn , Myra B. Kurtz , Jerrold M. Liesch , Jack L. Smith , Isabel Martin , Francisca Vicente
发明人： Wendy S. Horn , Myra B. Kurtz , Jerrold M. Liesch , Jack L. Smith , Isabel Martin , Francisca Vicente
IPC分类号： A01N37/44 , C07C229/30
CPC分类号： C07C229/30 , A01N37/44
摘要： New antibiotic eicosenoic acids and a method of producing it are described. The acids have been found to have antifungal properties.
摘要翻译： 描述了新的抗生素二十碳烯酸及其生产方法。 已经发现酸具有抗真菌性质。
-
公开(公告)号：US5702929A
公开(公告)日：1997-12-30
申请号：US734704
申请日：1996-10-21
申请人： Sandra A. Morris , James E. Curotto , Gerald F. Bills , Sarah J. Dreikorn , Stanley L. Streicher , Deborah L. Zink , John R. Thompson , Angela Basilio , Fernando Pelaez , Maria Teresa Diez , Francisca Vicente
发明人： Sandra A. Morris , James E. Curotto , Gerald F. Bills , Sarah J. Dreikorn , Stanley L. Streicher , Deborah L. Zink , John R. Thompson , Angela Basilio , Fernando Pelaez , Maria Teresa Diez , Francisca Vicente
IPC分类号： C07D405/06 , C12P17/16 , C12N5/00 , C07D207/00
CPC分类号： C07D405/06 , C12P17/16
摘要： There is disclosed a novel compound having the formula ##STR1## which exhibits antifungal activity.
摘要翻译： 公开了具有抗真菌活性的具有式（I）的化合物。
-
-
-
-
-
-
-
-
-
搜索结果
12 条记录 (耗时 0.013 秒)
