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1.发明授权公开(公告)号：US09180257B2
公开(公告)日：2015-11-10
申请号：US12923649
申请日：2010-09-30
CPC分类号： A61M5/3202 , A61J1/1406 , A61J1/201 , A61J1/2048 , A61J1/2055 , A61J1/2065 , A61J1/2096 , A61M5/001 , A61M5/158 , A61M5/3134 , A61M5/3287 , A61M39/0208 , A61M39/0247 , A61M2005/1587 , A61M2039/027 , A61M2039/0276 , A61M2039/0285 , A61M2039/0288 , A61M2039/0294
摘要： Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and assures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed.
摘要翻译： 提供了用于使用具有皮下注射口的注射器或笔式注射器通过注射口输送治疗物质的适配器和使用适配器的方法。 注射器适配器具有具有第一端和第二端的主体。 本体的第一端构造成接收和接合注射器的端部，使得注射器的套管相对于适配器保持在固定位置。 适配器的第二端被配置为与注入端口的配合部分配合。 当适配器的第二端接合注射口的配合部分时，适配器确保注射器的插管与皮下注射口适当地对齐并且确保插管将注射口穿透到合适的深度。 还公开了用于笔式传送系统的适配器。 此外，公开了一种用于便于从小瓶装载具有治疗物质的注射器的适配器。
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公开(公告)号：US6152868A
公开(公告)日：2000-11-28
申请号：US32931
申请日：1998-03-02
申请人： Michael R. Walters
发明人： Michael R. Walters
CPC分类号： B04B5/02 , B04B5/0414
摘要： An apparatus adaptable for use in a centrifuge apparatus to rotate a fluid tube about its longitudinal axis while the centrifuge apparatus is rotating the fluid tube in a rotational direction transverse to the longitudinal axis of the tube. The apparatus comprises an engaging member configured to engage a gear which is mechanically coupled to the fluid tube, and a driver configured to apply a driving force to the engaging member to cause the engaging member to engage and rotate the gear, which rotates the fluid tube about its longitudinal axis. The centrifuge apparatus can therefore obtain readings of the centrifuged sample from different locations about the circumference of the fluid tube at different orientations of the fluid tube.
摘要翻译： 适于在离心机设备中使用的装置，用于使流体管围绕其纵向轴线旋转，同时离心机设备在横向于管的纵向轴线的旋转方向上旋转流体管。 该装置包括接合构件，其构造成接合机械地联接到流体管的齿轮;以及驱动器，构造成将驱动力施加到接合构件，以使接合构件接合和旋转齿轮，所述齿轮使流体管 关于其纵轴。 因此，离心机设备可以在流体管的不同取向周围围绕流体管的周边的不同位置获得离心样品的读数。
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3.发明授权
公开(公告)号：US6135940A
公开(公告)日：2000-10-24
申请号：US210332
申请日：1998-12-11
申请人： Michael R. Walters
发明人： Michael R. Walters
CPC分类号： B04B5/02 , B04B5/0414
摘要： An apparatus is disclosed for use in a centrifuge apparatus to rotate a fluid tube about its longitudinal axis while the rotor of the centrifuge apparatus is rotating the fluid tube in a rotational direction transverse to the longitudinal axis of the tube. The apparatus comprises a cam which is mechanically coupled to the fluid tube, and a cam follower configured to apply a driving force to the cam to cause the cam to rotate, which in turn rotates the fluid tube about its longitudinal axis. The cam follower applies the driving force to the cam in response to changes in the magnitude of centrifugal force applied to the cam follower caused by increases and decreases in the speed of rotation of the rotor. The centrifuge apparatus can therefore obtain optical readings of the centrifuged sample from different locations about the circumference of the fluid tube.
摘要翻译： 公开了一种用于离心机设备中的装置，用于围绕其纵向轴线旋转流体管，同时离心机设备的转子在与管的纵向轴线相反的旋转方向上旋转流体管。 该装置包括机械地联接到流体管的凸轮和被配置为向凸轮施加驱动力以使凸轮旋转的凸轮从动件，凸轮从动件使流体管围绕其纵向轴线旋转。 凸轮从动件响应于由于转子的旋转速度的增加和减小而施加到凸轮从动件的离心力的大小的变化，凸轮从动件将驱动力施加到凸轮。 因此，离心机设备可以从流体管周围的不同位置获得离心样品的光学读数。
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公开(公告)号：US06285450B1
公开(公告)日：2001-09-04
申请号：US09033368
申请日：1998-03-02
申请人： Bradley S. Thomas , Michael A. Kelly , Michael R. Walters , Edward M. Skevington , Paul F. Gaidis
发明人： Bradley S. Thomas , Michael A. Kelly , Michael R. Walters , Edward M. Skevington , Paul F. Gaidis
IPC分类号： G01N2101
CPC分类号： B04B5/0407 , G01N15/042 , G01N2015/047
摘要： A centrifuge device that is used to centrifuge a fluid sample, such as a blood sample, to separate the fluid sample into its various component layers, and which is capable of measuring the length of the component layers to calculate cell counts for each layer. The centrifuge device includes a rotor assembly for rotating and thus centrifuging the fluid sample, and a movable optical reader device for reading the cell layers in the centrifuged sample. The centrifuge device is capable of accurately controlling the reading of the centrifuged sample based on the orientation of the rotor, so that the rotor can continue to rotate the centrifuged sample while the readings are being taken.
摘要翻译： 离心机装置，其用于离心流体样品，例如血液样品，以将流体样品分离成其各种组分层，并且其能够测量组分层的长度以计算每层的细胞计数。 离心机装置包括用于旋转和离心流体样品的转子组件和用于读取离心样品中的细胞层的可移动光学读取装置。 离心机装置能够基于转子的取向精确地控制离心样品的读数，使得当读数被读取时，转子可以继续旋转离心样品。
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公开(公告)号：US6120429A
公开(公告)日：2000-09-19
申请号：US33367
申请日：1998-03-02
申请人： Michael R. Walters
发明人： Michael R. Walters
CPC分类号： B04B5/0414 , B04B5/02
摘要： A method for rotating a fluid tube about its longitudinal axis while a centrifuge apparatus is rotating the fluid tube in a rotational direction transverse to the longitudinal axis of the tube by utilizing an apparatus comprising an engaging member configured to engage a gear which is mechanically coupled to the fluid tube, and a driver configured to apply a driving force to the engaging member to cause the engaging member to engage and rotate the gear, which rotates the fluid tube about its longitudinal axis. This method can therefore obtain readings of the centrifuged sample from different locations about the circumference of the fluid tube at different orientations of the fluid tube.
摘要翻译： 一种用于在离心机设备通过横向于管的纵向轴线的旋转方向旋转流体管的情况下使流体管绕其纵向轴线旋转的方法，该设备包括接合构件，该接合构件构造成与机械地联接到 所述流体管和驱动器构造成向所述接合构件施加驱动力，以使所述接合构件接合和旋转所述齿轮，所述齿轮围绕其纵向轴线旋转所述流体管。 因此，该方法可以在流体管的不同取向处从流体管的周围的不同位置获得离心样品的读数。
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公开(公告)号：US6074883A
公开(公告)日：2000-06-13
申请号：US33119
申请日：1998-03-02
CPC分类号： B01L3/50215 , B04B5/0407 , Y10T436/2575
摘要： A carrier tube system and method for using the same includes a carrier tube that is configured to receive a capillary blood tube, and a cap which seals the carrier tube to isolate the blood in the capillary tube from the surrounding atmosphere. The carrier tube system can be placed in a centrifuge which separates the blood with its component parts and optically reads the resulting layer thicknesses. The cap of the carrier tube can include a gear portion which is adapted for engagement with an indexing mechanism of the centrifuge, so that the indexing mechanism can rotate the carrier tube system about its longitudinal axis during centrifugation, thus allowing the optical reader of the centrifuge to take layer thickness readings at various positions about the circumference of the capillary tube. The cap can also include a float holder which holds a float that is inserted automatically into the capillary tube when the cap is placed
摘要翻译： 载体管系统及其使用方法包括配置为容纳毛细管血管的载体管和密封载体管以将毛细管中的血液与周围大气隔离的帽。 载体管系统可以放置在离心机中，离心机将血液与其组分部分分离，并光学读取所得的层厚度。 载体管的盖可以包括适于与离心机的分度机构接合的齿轮部分，使得分度机构可以在离心期间使载体管系统围绕其纵向轴线旋转，从而允许离心机的光学读取器 以在毛细管周围的各个位置上取层厚读数。 盖子还可以包括浮子保持器，该浮子保持器保持当盖子被放置时自动插入毛细管中的浮子
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7.发明授权
公开(公告)号：US6002474A
公开(公告)日：1999-12-14
申请号：US32934
申请日：1998-03-02
申请人： Bradley S. Thomas , Michael A. Kelly , Michael R. Walters , Edward M. Skevington , Paul F. Gaidis
发明人： Bradley S. Thomas , Michael A. Kelly , Michael R. Walters , Edward M. Skevington , Paul F. Gaidis
CPC分类号： B04B5/0407 , G01N15/042 , G01N2015/047 , G01N21/07
摘要： A centrifuge device that is used to centrifuge a fluid sample, such as a blood sample, to separate the fluid sample into its various component layers, and which is capable of measuring the length of the component layers to calculate cell counts for each layer. The centrifuge device includes a rotor assembly for rotating and thus centrifuging the fluid sample, and a movable optical reader device for reading the cell layers in the centrifuged sample. The centrifuge device is capable of accurately controlling the reading of the centrifuged sample based on the orientation of the rotor, so that the rotor can continue to rotate the centrifuged sample while the readings are being taken.
摘要翻译： 离心机装置，其用于离心流体样品，例如血液样品，以将流体样品分离成其各种组分层，并且其能够测量组分层的长度以计算每层的细胞计数。 离心机装置包括用于旋转和离心流体样品的转子组件和用于读取离心样品中的细胞层的可移动光学读取装置。 离心机装置能够基于转子的取向精确地控制离心样品的读数，使得当读数被读取时，转子可以继续旋转离心样品。
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公开(公告)号：US20110022006A1
公开(公告)日：2011-01-27
申请号：US12923649
申请日：2010-09-30
CPC分类号： A61M5/3202 , A61J1/1406 , A61J1/201 , A61J1/2048 , A61J1/2055 , A61J1/2065 , A61J1/2096 , A61M5/001 , A61M5/158 , A61M5/3134 , A61M5/3287 , A61M39/0208 , A61M39/0247 , A61M2005/1587 , A61M2039/027 , A61M2039/0276 , A61M2039/0285 , A61M2039/0288 , A61M2039/0294
摘要： Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and assures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed.
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公开(公告)号：US6080366A
公开(公告)日：2000-06-27
申请号：US33373
申请日：1998-03-02
CPC分类号： G01N21/07 , B01L9/06 , B04B5/02 , B04B5/0414 , G01N2035/00287 , G01N2035/00485 , G01N35/025
摘要： A carrier tube system and method for using the same includes a carrier tube that is configured to receive a capillary blood tube, and a cap which seals the carrier tube to isolate the blood in the capillary tube from the surrounding atmosphere. The carrier tube system can be placed in a centrifuge which separates the blood with its component parts and optically reads the resulting layer thicknesses. The cap of the carrier tube can include a gear portion which is adapted for engagement with an indexing mechanism of the centrifuge, so that the indexing mechanism can rotate the carrier tube system about its longitudinal axis during centrifugation, thus allowing the optical reader of the centrifuge to take layer thickness readings at various positions about the circumference of the capillary tube. The cap can also include a float holder which holds a float that is inserted automatically into the capillary tube when the cap is placed.
摘要翻译： 载体管系统及其使用方法包括配置为容纳毛细管血管的载体管和密封载体管以将毛细管中的血液与周围大气隔离的帽。 载体管系统可以放置在离心机中，离心机将血液与其组分部分分离，并光学读取所得的层厚度。 载体管的盖可以包括适于与离心机的分度机构接合的齿轮部分，使得分度机构可以在离心期间使载体管系统围绕其纵向轴线旋转，从而允许离心机的光学读取器 以在毛细管周围的各个位置上取层厚读数。 盖子还可以包括浮子保持器，该浮子保持器保持当盖子被放置时自动插入毛细管中的浮子。
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10.发明授权公开(公告)号：US08002756B2
公开(公告)日：2011-08-23
申请号：US11948804
申请日：2007-11-30
CPC分类号： A61M5/3202 , A61J1/1406 , A61J1/201 , A61J1/2048 , A61J1/2055 , A61J1/2065 , A61J1/2096 , A61M5/001 , A61M5/158 , A61M5/3134 , A61M5/3287 , A61M39/0208 , A61M39/0247 , A61M2005/1587 , A61M2039/027 , A61M2039/0276 , A61M2039/0285 , A61M2039/0288 , A61M2039/0294
摘要： Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and assures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed.
摘要翻译： 提供了用于使用具有皮下注射口的注射器或笔式注射器通过注射口输送治疗物质的适配器和使用适配器的方法。 注射器适配器具有具有第一端和第二端的主体。 本体的第一端构造成接收和接合注射器的端部，使得注射器的套管相对于适配器保持在固定位置。 适配器的第二端被配置为与注入端口的配合部分配合。 当适配器的第二端接合注射口的配合部分时，适配器确保注射器的插管与皮下注射口适当地对齐并且确保插管将注射口穿透到合适的深度。 还公开了用于笔式传送系统的适配器。 此外，公开了一种用于便于从小瓶装载具有治疗物质的注射器的适配器。
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