公开(公告)号：US08190034B2

公开(公告)日：2012-05-29

申请号：US12362836

申请日：2009-01-30

申请人： Moriyasu Ichino ,  Junichi Kataoka ,  Seiichi Ishikura

发明人： Moriyasu Ichino ,  Junichi Kataoka ,  Seiichi Ishikura

IPC分类号： H04B10/06 ,  G01J1/44

CPC分类号： H04J14/0226 ,  H04B10/6911 ,  H04J14/0232 ,  H04J14/0247 ,  H04J14/0252

摘要： An optical receiver is disclosed, in which no additional photodiode to monitor the optical input level and no temperature control unit are necessary. The receiver of the invention provides an avalanche photodiode (APD) to receiver the first optical signal with the first wavelength and a PIN-PD to receive the second optical signal with the second wavelength. The optical input level for the APD is indirectly determined through the photocurrent generated by the PIN-PD and the bias voltage for the APD is so adjusted that the APD shows an optimum multiplication factor for the optical input level.

摘要翻译： 公开了一种光接收器，其中不需要额外的光电二极管来监视光输入电平并且不需要温度控制单元。 本发明的接收机提供雪崩光电二极管（APD）以接收具有第一波长的第一光信号和PIN-PD以接收具有第二波长的第二光信号。 通过由PIN-PD产生的光电流间接地确定APD的光输入电平，并且对APD的偏置电压进行如此调整，使得APD显示用于光输入电平的最佳乘法因子。

公开(公告)号：US20070152138A1

公开(公告)日：2007-07-05

申请号：US11712497

申请日：2007-03-01

申请人： Moriyasu Ichino

发明人： Moriyasu Ichino

IPC分类号： H01L31/00

CPC分类号： H01L31/107 ,  H01L31/02027

摘要： The present invention provides a method to maintain a multiplication factor of an avalanche photodiode independent on temperatures without additional devices. The light-receiving apparatus of the invention includes an avalanche photodiode (APD), a dividing circuit, and a bias supplying circuit. The APD has a first region, where a significant multiplication factor appears, and a second region without any multiplication factor. The dividing circuit extracts a second signal

摘要翻译： 本发明提供一种在没有附加装置的情况下保持雪崩光电二极管的倍增因子独立于温度的方法。 本发明的光接收装置包括雪崩光电二极管（APD），分压电路和偏压供给电路。 APD具有出现显着倍增因子的第一区域，而没有任何乘法因子的第二区域。 分频电路提取第二信号

公开(公告)号：US07227119B2

公开(公告)日：2007-06-05

申请号：US11118347

申请日：2005-05-02

申请人： Yukio Sato ,  Moriyasu Ichino

发明人： Yukio Sato ,  Moriyasu Ichino

IPC分类号： H03F3/08

CPC分类号： H03F3/08 ,  G11B7/126 ,  H03F3/343 ,  H03G1/0088 ,  H03G3/3084

摘要： A current voltage converter circuit includes a light receiving element which receives a light output from a laser and generates a light current according to the light output, a current distributor circuit which distributes the light current from the light receiving element, the current distributor circuit being configured of a current mirror circuit which includes a transistor pair and a first operating amplifier. The current voltage converter circuit further includes a voltage converter circuit which converts a current distributed by the current distributor circuit into a voltage, the voltage converter circuit including a second operating amplifier.

摘要翻译： 电流电压转换器电路包括接收来自激光器的光输出并根据光输出产生光电流的光接收元件，分配来自光接收元件的光电流的分流器电路，配置电流分配器电路 包括晶体管对和第一运算放大器的电流镜电路。 当前的电压转换器电路还包括电压转换器电路，其将由分配器电路分配的电流转换成电压，该电压转换器电路包括第二运算放大器。

公开(公告)号：US20100322271A1

公开(公告)日：2010-12-23

申请号：US12817251

申请日：2010-06-17

申请人： Moriyasu ICHINO ,  Hiroto Ishibashi ,  Toru Ukai ,  Yuanzhe Li

发明人： Moriyasu ICHINO ,  Hiroto Ishibashi ,  Toru Ukai ,  Yuanzhe Li

IPC分类号： H01S3/10

CPC分类号： H01S5/06832 ,  H01S5/06804

摘要： A method to control an LD (laser diode) is disclosed. The method compares the operating temperature of the LD with a transition temperature. When the former temperature exceeds the latter, the modulation current is set based on the bias current, which is independently determined by the APC loop. On the other hand, the operating temperature is less than the transition temperature; the modulation current is determined by the operating temperature.

摘要翻译： 公开了一种控制LD（激光二极管）的方法。 该方法将LD的工作温度与转变温度进行比较。 当前一种温度超过后者时，调制电流基于由APC回路独立确定的偏置电流来设定。 另一方面，工作温度小于转变温度; 调制电流由工作温度决定。

公开(公告)号：US20090257917A1

公开(公告)日：2009-10-15

申请号：US12083694

申请日：2006-10-16

申请人： Hideaki Nakamura ,  Masao Gotoh ,  Tomoko Ishikawa ,  Isao Karube ,  Toshifumi Hosoya ,  Shingo Kaimori ,  Moriyasu Ichino

发明人： Hideaki Nakamura ,  Masao Gotoh ,  Tomoko Ishikawa ,  Isao Karube ,  Toshifumi Hosoya ,  Shingo Kaimori ,  Moriyasu Ichino

IPC分类号： B01J19/00 ,  B32B37/00

CPC分类号： G01N27/3271 ,  Y10T156/1051

摘要： It is intended to provide a sensor chip which has a small size and is easily produced and capable of determining quantities of at least two components of multiple samples rapidly, conveniently, and correctly as well as to provide a production method capable of producing the sensor chip easily and with high productivity.A sensor chip includes a substrate, a cover layer, a spacer layer sandwiched between the substrate and the cover layer, multiple reaction portions disposed between the substrate and the cover layer, multiple detection units exposed in the hollow reaction portions, and a sample inlet communicated with the hollow reaction portions and a method for producing the sensor chip.A sensor chip includes two substrates opposed to each other, a spacer layer sandwiched between the substrates, and multiple measurement units disposed between the substrates and including two or more hollow reaction portions that share one sample inlet opened on outer surfaces of the substrates and detection electrode units respectively exposed in the hollow reaction portions and a method for producing the sensor chip.

摘要翻译： 本发明旨在提供一种具有体积小且容易制造且能够快速，方便和正确地确定多个样品的至少两个组分的量的传感器芯片，以及提供能够生产传感器芯片的制造方法 容易和高生产力。 传感器芯片包括衬底，覆盖层，夹在衬底和覆盖层之间的间隔层，设置在衬底和覆盖层之间的多个反应部分，暴露在中空反应部分中的多个检测单元和连通的样品入口 中空反应部分和传感器芯片的制造方法。 传感器芯片包括彼此相对的两个基板，夹在基板之间的间隔层和设置在基板之间的多个测量单元，并且包括两个或更多个中空反应部分，其共享在基板的外表面上开放的一个样品入口和检测电极 分别暴露在中空反应部分中的单元和传感器芯片的制造方法。

公开(公告)号：US20090152127A1

公开(公告)日：2009-06-18

申请号：US11992102

申请日：2006-09-08

申请人： Shingo Kaimori ,  Toshifumi Hosoya ,  Moriyasu Ichino ,  Takahiko Kitamura ,  Isao Karube ,  Masao Gotoh ,  Hideaki Nakamura ,  Tomoko Ishikawa

发明人： Shingo Kaimori ,  Toshifumi Hosoya ,  Moriyasu Ichino ,  Takahiko Kitamura ,  Isao Karube ,  Masao Gotoh ,  Hideaki Nakamura ,  Tomoko Ishikawa

IPC分类号： G01N27/327 ,  G01N27/26 ,  G01N27/04 ,  G01N27/416

CPC分类号： G01N27/3273

摘要： Provided are a biosensor chip measurement machine that can obtain accurate measurement results within a short period of time by employing only a tiny amount as a sample, and a measurement method therefor.A biosensor measurement machine 20 includes a power source 21, which is connected to a voltage regulator 22, a measurement instrument 23, and a controller 24 for supplying power. When a biosensor chip 1 is connected to the biosensor measurement machine 20 and a voltage is applied, the measurement instrument begins the measurement of a current value for a biosensor. When a measured current value or a measured charge value is greater than a reference value, the measurement is ended in accordance with an instruction issued by the controller 24, and when the value is smaller than the reference value, the measurement is continued in accordance with a controller instruction.

摘要翻译： 提供一种生物传感器芯片测量机，其可以通过仅使用微量作为样品而在短时间内获得准确的测量结果及其测量方法。 生物传感器测量机20包括连接到电压调节器22的电源21，测量仪器23和用于供电的控制器24。 当生物传感器芯片1连接到生物传感器测量机20并施加电压时，测量仪器开始测量生物传感器的当前值。 当测量的电流值或测量的电荷值大于参考值时，根据控制器24发出的指令结束测量，并且当该值小于参考值时，根据 控制器指令。

公开(公告)号：US20090053105A1

公开(公告)日：2009-02-26

申请号：US11795893

申请日：2006-01-23

申请人： Toshifumi Hosoya ,  Shingo Kaimori ,  Moriyasu Ichino ,  Hideaki Nakamura ,  Masao Gotoh ,  Fumiyo Kurusu ,  Tomoko Ishikawa ,  Isao Karube

发明人： Toshifumi Hosoya ,  Shingo Kaimori ,  Moriyasu Ichino ,  Hideaki Nakamura ,  Masao Gotoh ,  Fumiyo Kurusu ,  Tomoko Ishikawa ,  Isao Karube

IPC分类号： B01J19/00

CPC分类号： G01N33/54373 ,  B01L3/502707 ,  B01L2300/0645 ,  B01L2300/0822 ,  B01L2300/168

摘要： There is provided a sensor chip including: a base plate; a cover layer; a hollow reaction portion provided between the base plate and the cover layer, in which a reaction is performed between a sample and a reagent applied thereinto; a sensing member constructed of an electrode which is exposed to the hollow reaction portion; and a sample inlet for conducting the sample to the hollow reaction portion, wherein entire portions of the base plate and the cover layer, which are located opposite to the sensing member provided with the hollow reaction portion, are made transparent. Otherwise, in the above-described sensor chip, a plate A having a groove A to which a reagent has been applied and a plate B having a groove B are stacked on each other in such a manner that the groove A is coupled with the groove B, so that the hollow reaction portion is formed; and an opening width of the groove B is larger than an opening width of the groove A at a portion of the groove B which is located opposite to a portion with the groove A, to which the reagent has been applied.

摘要翻译： 提供了一种传感器芯片，包括：基板; 覆盖层; 设置在基板和覆盖层之间的中空反应部分，其中在样品和施加于其之间的试剂之间进行反应; 由暴露于中空反应部分的电极构成的传感部件; 以及用于将样品导引到中空反应部分的样品入口，其中与设置有中空反应部分的感测构件相对的基板和覆盖层的整个部分被制成透明的。 另外，在上述传感器芯片中，将具有涂敷有试剂的槽A的板A和具有槽B的板B彼此堆叠，使得槽A与槽 B，形成中空反应部分; 并且槽B的开口宽度大于槽B的与已经施加有试剂的部分的与槽A相对的部分处的槽A的开口宽度。

公开(公告)号：US20090020420A1

公开(公告)日：2009-01-22

申请号：US11921166

申请日：2006-10-16

申请人： Takahiko Kitamura ,  Toshifumi Hosoya ,  Shingo Kaimori ,  Moriyasu Ichino ,  Hideaki Nakamura ,  Isao Karube ,  Masao Gotoh ,  Tomoko Ishikawa

发明人： Takahiko Kitamura ,  Toshifumi Hosoya ,  Shingo Kaimori ,  Moriyasu Ichino ,  Hideaki Nakamura ,  Isao Karube ,  Masao Gotoh ,  Tomoko Ishikawa

IPC分类号： G01N27/327 ,  B05D5/00

CPC分类号： C12Q1/002

摘要： It is intended to provide a biosensor chip capable of rapid and correct measurement, including a reaction chamber that enables a measurement of a very small amount of a measurement sample and has a small capacity and potassium ferricyanide having a very small crystal particle size disposed in the reaction chamber.In a biosensor chip 1, electrodes 3 and 4 are disposed on the lower substrate 2, and lower spacer 5 (7 and 8) is adhered on the electrodes 3 and 4. An upper spacer 11 (12 and 13) is adhered to an upper substrate 15, and a lower spacer 5 is attached to the upper spacer 11 by and adhesive agent 10. A lower groove 9 is formed between long and short lower spacers 7 and 8, and an upper groove 14 is formed between long and short spacers 12 and 13, so that a reaction chamber 17 is formed by the upper and lower grooves 9 and 14. A capacity of the reaction chamber is 0.3 μL, and an enzyme 18 and potassium ferricyanide are disposed in the reaction chamber 17 in such a fashion as to oppose to each other with a gap being defined therebetween. A crystal particle diameter of the potassium ferricyanide is 100 μm or less, and amount of the potassium ferricyanide is V×0.1 mg or more when the capacity of the reaction chamber 17 is V.

摘要翻译： 旨在提供能够快速且正确测量的生物传感器芯片，其包括能够测量非常少量的测量样品并且具有小容量的反应室和具有非常小的晶粒度的铁氰化钾 反应室。 在生物传感器芯片1中，电极3和4设置在下基板2上，下隔片5（7和8）粘附在电极3和4上。上间隔件11（12和13） 基板15和下隔板5通过粘合剂10附接到上间隔件11.下槽9形成在长和短下隔板7和8之间，并且上槽14形成在长间隔件12和短间隔件12之间 和13，使得反应室17由上下槽9和14形成。反应室的容量为0.3微米，酶18和铁氰化钾以如下方式设置在反应室17中： 彼此相对，在其间限定间隙。 当反应室17的容量为V时，铁氰化钾的晶粒直径为100μm以下，铁氰化钾的量为Vx0.1mg以上。

公开(公告)号：US07309853B2

公开(公告)日：2007-12-18

申请号：US11305347

申请日：2005-12-19

申请人： Kenichiro Uchida ,  Moriyasu Ichino

发明人： Kenichiro Uchida ,  Moriyasu Ichino

IPC分类号： G01J1/44 ,  H01J40/14 ,  H03F3/08

CPC分类号： H04B10/66

摘要： The invention discloses an optical receiver that prevents the instability of the bias voltage to the avalanche photodiode (APD) and facilitates the recovery of the bias voltage from the safety value. The optical receiver comprises the APD, the DC-DC converter to supply the bias voltage to the APD, the current detector to detect the photo current generated by the APD, and the controller to set the bias voltage. The controller, evaluating the optical input power based on the output voltage of the DC-DC converter and the monitored current, sets the output voltage based on the change of the optical input power.

摘要翻译： 本发明公开了一种光接收器，其防止偏置电压对雪崩光电二极管（APD）的不稳定性，并且有助于从安全值恢复偏置电压。 光接收器包括APD，DC-DC转换器，用于向APD提供偏置电压，电流检测器检测由APD产生的光电流，并且控制器设置偏置电压。 控制器基于DC-DC转换器的输出电压和监视电流来评估光输入功率，基于光输入功率的变化来设置输出电压。

公开(公告)号：US07214924B2

公开(公告)日：2007-05-08

申请号：US11488077

申请日：2006-07-18

申请人： Moriyasu Ichino

发明人： Moriyasu Ichino

IPC分类号： H01J40/14

CPC分类号： H01L31/107 ,  H01L31/02027

摘要： The present invention provides a method to maintain a multiplication factor of an avalanche photodiode independent on temperatures without additional devices. The light-receiving apparatus of the invention includes an avalanche photodiode (APD), a dividing circuit, and a bias supplying circuit. The APD has a first region, where a significant multiplication factor appears, and a second region without any multiplication factor. The dividing circuit extracts a second signal.

摘要翻译： 本发明提供一种在没有附加装置的情况下保持雪崩光电二极管的倍增因子独立于温度的方法。 本发明的光接收装置包括雪崩光电二极管（APD），分压电路和偏压供给电路。 APD具有出现显着倍增因子的第一区域和没有任何乘法因子的第二区域。 分频电路提取第二信号。