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    METHOD OF ANTIOXIDATIVE FUNCTIONAL ESTIMATION USING ANIMAL MODEL
    1.
    发明申请
    METHOD OF ANTIOXIDATIVE FUNCTIONAL ESTIMATION USING ANIMAL MODEL 审中-公开
    使用动物模型的抗氧化功能评估方法

    公开(公告)号：US20090263906A1

    公开(公告)日：2009-10-22

    申请号：US12252917

    申请日：2008-10-16

    申请人： Il-Yun JEONG ,  Yong Dae PARK ,  Chang-Hyun JIN ,  Dae-Seong CHOI ,  Myung-Woo BYUN ,  Hyo-Jung LEE

    发明人： Il-Yun JEONG ,  Yong Dae PARK ,  Chang-Hyun JIN ,  Dae-Seong CHOI ,  Myung-Woo BYUN ,  Hyo-Jung LEE

    IPC分类号： G01N33/92

    CPC分类号： G01N33/5088 ,  G01N33/84 ,  G01N33/92 ,  G01N2500/00

    摘要： The present invention relates to a method of antioxidative functional estimation using an animal model, more precisely a method of antioxidative functional estimation using mice having oxidative damage caused by reactive oxygen species induced by irradiation and having lipid hydroperoxide secreted in the urine which might be index for quantitative and qualitative analysis for antioxidative functional estimation. The method of antioxidative functional estimation of the present invention can be effectively used for the screening of a novel anti-oxidant agent or antioxidative functional health food to regulate the production of lipid hydroperoxide.

    摘要翻译： 本发明涉及使用动物模型的抗氧化功能评估方法，更确切地说，使用由辐射诱导的活性氧所引起的具有氧化损伤的小鼠的抗氧化功能评估方法，并且具有分泌在尿液中的脂质氢过氧化物 抗氧化功能评估的定量和定性分析。 本发明的抗氧化功能评价方法可以有效地用于筛选新的抗氧化剂或抗氧化功能保健食品，以调节脂质氢过氧化物的产生。

    Preparation method of radioisotope labeling compound using carbon nanotube
    4.
    发明申请
    Preparation method of radioisotope labeling compound using carbon nanotube 有权
    使用碳纳米管的放射性同位素标记化合物的制备方法

    公开(公告)号：US20080214797A1

    公开(公告)日：2008-09-04

    申请号：US11788801

    申请日：2007-04-20

    申请人： Sang Hyun Park ,  Hui Jeong Gwon ,  Myung Woo Byun

    发明人： Sang Hyun Park ,  Hui Jeong Gwon ,  Myung Woo Byun

    IPC分类号： C07F13/00 ,  C07C279/02

    CPC分类号： C07F13/005 ,  C07C277/00 ,  C07C279/06

    摘要： Disclosed herein is a method for the preparation of radioisotope-labeled compounds using CNT. It comprises filling the carbon nanotube with a radioisotope; and labeling a physiologically active material with the radioisotope charged in the carbon nanotube. Taking advantage of CNT, the method can prepare a radioisotope-labeled compound invention at a high yield and in a simple manner. Also, the radioisotope, when remaining unreacted, can be recovered by the filtration of the CNT, thereby achieving the prevention of radioactive contamination and the reduction of radioactive waste. Further, the radioisotope-labeled compound is useful as a contrast medium for imaging the hepatobiliary system.

    摘要翻译： 本文公开了使用CNT制备放射性同位素标记化合物的方法。 它包括用放射性同位素填充碳纳米管; 并用放入碳纳米管的放射性同位素标记生理活性物质。 利用CNT，该方法可以以高产率和简单的方式制备放射性同位素标记的化合物。 此外，当保留未反应时，放射性同位素可以通过过滤CNT来回收，从而实现放射性污染的防止和放射性废物的减少。 此外，放射性同位素标记的化合物可用作成像肝胆系统的造影剂。

    Preparation method of radioisotope labeling compound using carbon nanotube
    5.
    发明授权
    Preparation method of radioisotope labeling compound using carbon nanotube 有权
    使用碳纳米管的放射性同位素标记化合物的制备方法

    公开(公告)号：US08247538B2

    公开(公告)日：2012-08-21

    申请号：US11788801

    申请日：2007-04-20

    申请人： Sang Hyun Park ,  Hui Jeong Gwon ,  Myung Woo Byun

    发明人： Sang Hyun Park ,  Hui Jeong Gwon ,  Myung Woo Byun

    IPC分类号： C07F13/00 ,  C07C279/02

    CPC分类号： C07F13/005 ,  C07C277/00 ,  C07C279/06

    摘要： Disclosed herein is a method for the preparation of radioisotope-labeled compounds using CNT. It comprises filling the carbon nanotube with a radioisotope; and labeling a physiologically active material with the radioisotope charged in the carbon nanotube. Taking advantage of CNT, the method can prepare a radioisotope-labeled compound invention at a high yield and in a simple manner. Also, the radioisotope, when remaining unreacted, can be recovered by the filtration of the CNT, thereby achieving the prevention of radioactive contamination and the reduction of radioactive waste. Further, the radioisotope-labeled compound is useful as a contrast medium for imaging the hepatobiliary system.

    摘要翻译： 本文公开了使用CNT制备放射性同位素标记化合物的方法。 它包括用放射性同位素填充碳纳米管; 并用放入碳纳米管的放射性同位素标记生理活性物质。 利用CNT，该方法可以以高产率和简单的方式制备放射性同位素标记的化合物。 此外，当保留未反应时，放射性同位素可以通过过滤CNT来回收，从而实现放射性污染的防止和放射性废物的减少。 此外，放射性同位素标记的化合物可用作成像肝胆系统的造影剂。

    THE BIOCHIP FOR THE DETECTION OF PHOSPHORYLATION AND THE DETECTION METHOD USING THE SAME
    6.
    发明申请
    THE BIOCHIP FOR THE DETECTION OF PHOSPHORYLATION AND THE DETECTION METHOD USING THE SAME 审中-公开
    用于检测磷酸化的生物技术和使用其的检测方法

    公开(公告)号：US20100029507A1

    公开(公告)日：2010-02-04

    申请号：US11776969

    申请日：2007-07-12

    申请人： Sang Hyun Park ,  Hui Jeong Gwon ,  Kyong Cheol Ko ,  Myung Woo Byun

    发明人： Sang Hyun Park ,  Hui Jeong Gwon ,  Kyong Cheol Ko ,  Myung Woo Byun

    IPC分类号： C40B30/08 ,  C40B40/10

    CPC分类号： C12Q1/485 ,  B01J2219/00605 ,  B01J2219/00612 ,  B01J2219/00637 ,  G01N33/54353 ,  G01N2500/00

    摘要： The present invention relates to a biochip for the detection of phosphorylation and a method for measuring phosphorylation using the same, more precisely a biochip integrated with the substrate of kinase and a kit for measuring phosphorylation comprising the biochip and a radio-labeled co-factor, and a method for measuring phosphorylation using the same. The kit for the detection of phosphorylation of the present invention facilitates simple and fast measurement of phosphorylation with a minimum amount of a sample, compared with the conventional method using an antibody, because it uses a radioisotope. This chip and kit can be effectively used for the analysis of kinase activity since this method favors fast mass analysis.

    摘要翻译： 本发明涉及用于检测磷酸化的生物芯片和使用其的磷酸化测定方法，更确切地说，与激酶底物整合的生物芯片和用于测量磷酸化的试剂盒包括生物芯片和放射性标记的辅因子， 以及使用其测定磷酸化的方法。 与使用抗体的常规方法相比，本发明的用于检测本发明的磷酸化的试剂盒由于使用放射性同位素，与使用抗体的常规方法相比，促进了用最少量的样品简单且快速地测量磷酸化。 该芯片和试剂盒可以有效地用于激酶活性的分析，因为该方法有利于快速质量分析。

    Herbal composition for improving anticancer activity, immune response and hematopoiesis of the body, and protecting the body from oxidative damage, and the method of preparing the same
    8.
    发明授权
    Herbal composition for improving anticancer activity, immune response and hematopoiesis of the body, and protecting the body from oxidative damage, and the method of preparing the same 有权
    用于改善抗癌活性，身体免疫应答和造血作用以及保护身体免受氧化损伤的草药组合物及其制备方法

    公开(公告)号：US06964785B2

    公开(公告)日：2005-11-15

    申请号：US10648416

    申请日：2003-08-25

    申请人： Sung Kee Jo ,  Sung Ho Kim ,  Sung Tae Yee ,  Hae Ran Park ,  Heon Oh ,  Myung Woo Byun

    发明人： Sung Kee Jo ,  Sung Ho Kim ,  Sung Tae Yee ,  Hae Ran Park ,  Heon Oh ,  Myung Woo Byun

    IPC分类号： A23L1/30 ,  A61K31/715 ,  A61K36/00 ,  A61K36/10 ,  A61K36/232 ,  A61K36/234 ,  A61K36/65 ,  A61P7/00 ,  A61P35/00 ,  A61P37/04 ,  A61P43/00 ,  A61K35/78

    CPC分类号： A61K36/234 ,  A61K36/232 ,  A61K36/65 ,  A61K2300/00

    摘要： Disclosed is a herbal composition comprising a first hot-water extract from a mixture of the plants Angelicae gigantis Radix, Cnidium officinale Makino and Paeonia japonica Miyabe et Takeda at an equal weight ratio, and a polysaccharide fraction as a precipitate formed by adding ethanol to a second hot-water extract from a mixture of the plants Angelicae gigantis Radix, Cnidium officinale Makino and Paeonia japonica Miyabe et Takeda at an equal weight ratio. The herbal composition of the present invention is effective in improving the anticancer activity, immune response and hematopoiesis of the body, and protecting the body from oxidative damage. Therefore, by stimulating the recovery from the damage to the immune function and hematopoietic function, often occurring during chemotherapy and radiotherapy, and inhibiting oxidative damage, the herbal composition can be applied for the prevention of the side effects of cancer therapy, as well as for the prevention of various degenerative chronic diseases and the improvement of the health of the weak and the elderly.

    摘要翻译： 公开了一种草药组合物，其包含以等重量比来自植物当归，，藜和芍药的混合物的第一热水提取物和通过向乙醇中加入乙醇形成的沉淀物的多糖部分 第二热水提取物，以相当重量比从当归植物当归，，藜和芍药Mi e和武田的混合物中提取。 本发明的草药组合物在改善身体的抗癌活性，免疫应答和造血作用以及保护身体免受氧化损伤方面是有效的。 因此，通过刺激从免疫功能和造血功能的损伤中恢复，通常在化疗和放疗期间发生，并抑制氧化损伤，草药组合物可用于预防癌症治疗的副作用，以及 预防各种退行性慢性病，改善弱者和老年人的健康。

    Manufacturing method of space Kimchi with shelf stability under the severe environment
    9.
    发明授权
    Manufacturing method of space Kimchi with shelf stability under the severe environment 有权
    泡菜的制作方法，在恶劣环境下具有稳定的货架

    公开(公告)号：US07871654B2

    公开(公告)日：2011-01-18

    申请号：US11701840

    申请日：2007-02-02

    申请人： Myung-Woo Byun ,  Ju-Woon Lee ,  Jae-Hun Kim

    发明人： Myung-Woo Byun ,  Ju-Woon Lee ,  Jae-Hun Kim

    IPC分类号： A23L3/26 ,  A23B7/10

    CPC分类号： A23B7/148 ,  A23B7/005 ,  A23B7/015 ,  A23B7/04 ,  A23B7/10 ,  A23B7/105 ,  A23L19/00 ,  A23L19/20

    摘要： The present invention relates to a manufacturing method of kimchi with shelf stability and high quality under the severe environment, more precisely, a manufacturing method of kimchi with shelf stability and high quality under the severe environment such as desert, alpine regions, poles and space which includes the step of irradiation after heating, gas exchange packaging and quick freezing. The manufacturing method of kimchi of the present invention reduces the chances of deterioration of the sensory quality and physicochemical characteristics caused by the conventional sterilization methods including high temperature and high pressure treatment and high dose of irradiation, so that kimchi produced by this method has excellent shelf stability under the severe environment.

    摘要翻译： 本发明涉及在恶劣环境下具有稳定性和高质量的泡菜的制造方法，更具体而言，是在沙漠，高山，极地和空间等恶劣环境下具有稳定性和高质量的泡菜的制造方法。 包括加热后的照射步骤，气体交换包装和快速冷冻。 本发明的泡菜的制造方法降低了由高温高压处理和高剂量照射引起的常规杀菌方法引起的感官质量下降和物理化学特性的可能性，使得通过该方法制造的泡菜具有优异的搁架 在恶劣环境下的稳定。

    Technetium-99m-labeled organic germanium nanocolloids, method of preparing the same and use thereof
    10.
    发明授权
    Technetium-99m-labeled organic germanium nanocolloids, method of preparing the same and use thereof 有权
    锝-99m标记的有机锗纳米胶体及其制备方法及其应用

    公开(公告)号：US07459141B2

    公开(公告)日：2008-12-02

    申请号：US11474717

    申请日：2006-06-26

    申请人： Sang Hyun Park ,  Hui Jeong Gwon ,  Myung Woo Byun

    发明人： Sang Hyun Park ,  Hui Jeong Gwon ,  Myung Woo Byun

    IPC分类号： A61K51/00 ,  C07J13/00

    CPC分类号： C07F13/005 ,  A61K51/0478 ,  A61K51/1217

    摘要： Disclosed relates to organic germanium nanocolloids, to which technetium-99m (99mTc), a radionuclide, is labeled, method of the same, and a spleen-imaging agent including the same. According to the invention, 99mTc-labeled organic germanium nanocolloids having high labeling efficiency and stability can be provided. Moreover, since the 99mTc-labeled organic germanium nanocolloids of the invention are accumulated in the spleen considerably higher than the conventional spleen-imaging agent, it is possible to use the 99mTc-labeled organic germanium nanocolloids of the present invention as a therapeutic radiopharmaceutical for the spleen imaging.

    摘要翻译： 涉及有机锗纳米胶体，锝-99m（99mTc），放射性核素被标记，其方法和包括其的脾显像剂。 根据本发明，可以提供具有高标记效率和稳定性的99mTc标记的有机锗纳米胶体。 此外，由于本发明的99mTc标记的有机锗纳米胶体在脾脏中积累显着高于常规脾显像剂，因此可以使用本发明的99mTc标记的有机锗纳米胶体作为治疗性放射性药物 脾脏成像。