METHODS FOR DEGRADING NUCLEIC ACID
    5.
    发明申请
    METHODS FOR DEGRADING NUCLEIC ACID 有权
    降解核酸的方法

    公开(公告)号:US20140170021A1

    公开(公告)日:2014-06-19

    申请号:US14107253

    申请日:2013-12-16

    申请人: NanoMR, Inc.

    发明人: Sergey A. Dryga

    IPC分类号: G01N1/34

    摘要: Methods for degrading contaminant nucleic acid. The methods use combinations of metal ions and peroxide ions to produce a variety of oxidative species that degrade nucleic acid. Methods of the invention are useful for decontaminating laboratory equipment or solutions. After the equipment or solutions have been decontaminated, the metal ion and peroxide ion solution can be deactivated by raising the temperature to dissociate the peroxide or by binding the metal ions, e.g., with a chelating agent.

    摘要翻译: 降解污染物核酸的方法。 该方法使用金属离子和过氧化物离子的组合来产生降解核酸的各种氧化物质。 本发明的方法可用于净化实验室设备或溶液。 在设备或溶液已被去污染之后,金属离子和过氧化物离子溶液可以通过升高温度来解离过氧化物或通过例如与螯合剂结合金属离子而失活。

    TARGET CAPTURE SYSTEM
    7.
    发明申请
    TARGET CAPTURE SYSTEM 有权
    目标捕获系统

    公开(公告)号:US20140170652A1

    公开(公告)日:2014-06-19

    申请号:US14107315

    申请日:2013-12-16

    申请人: NanoMR, Inc.

    IPC分类号: C12Q1/24

    摘要: The invention generally relates to a system for isolating or separating a target from a sample. In certain aspects, processes performed by the target capture system include introducing a plurality of magnetic particles, in which a plurality of the particles include at least one binding moiety specific to a target, into a sample to form at least one target/particle complex and applying a magnetic field to isolate the magnetic particle/target complexes from the sample. The process starts at inputting a sample into the system and ends at delivering a capture target or nucleic acids of the target into a container for further analysis.

    摘要翻译: 本发明一般涉及用于从样品中分离或分离靶的系统。 在某些方面,由靶捕获系统执行的过程包括将多个粒子包括至少一个与靶特异性的结合部分的多个磁性颗粒引入到样品中以形成至少一个靶/颗粒复合体,以及 施加磁场以从样品中分离磁性颗粒/目标络合物。 该过程开始于将样品输入到系统中,并将目标物的捕获靶或核酸输送到容器中以进行进一步分析。

    METHODS FOR RAISING ANTIBODIES
    9.
    发明申请
    METHODS FOR RAISING ANTIBODIES 有权
    提高抗体的方法

    公开(公告)号:US20140171340A1

    公开(公告)日:2014-06-19

    申请号:US14132099

    申请日:2013-12-18

    申请人: NanoMR, Inc.

    IPC分类号: C12Q1/68

    CPC分类号: C07K16/12 G06F19/14

    摘要: The present invention generally relates to methods of generating antibodies against a species of pathogen that involve identifying the pathogen that is most genetically representative of member of pathogen species and using the identified pathogen to generate an antibody.

    摘要翻译: 本发明一般涉及产生针对病原体种类的抗体的方法,其涉及鉴定最具遗传代表病原体物种成员的病原体并使用鉴定的病原体产生抗体。

    AFFINITY MEDIUM USING FIXED WHOLE CELLS
    10.
    发明申请
    AFFINITY MEDIUM USING FIXED WHOLE CELLS 审中-公开
    使用固定的全细胞的亲和介质

    公开(公告)号:US20140170727A1

    公开(公告)日:2014-06-19

    申请号:US14132399

    申请日:2013-12-18

    申请人: NANOMR, INC.

    IPC分类号: C07K16/12

    CPC分类号: C07K16/1271 C07K1/22

    摘要: Separation media comprising a support and crosslinked whole cells fixed to the support. The separation media are useful in affinity columns for the separation of the antibodies from a solution, particularly for the separation of polyclonal antibodies that have been raised against the same type of whole cells. In an embodiment, the whole cells are whole bacterial cells.

    摘要翻译: 分离介质包括固定在载体上的载体和交联的全细胞。 分离介质可用于从溶液中分离抗体的亲和柱,特别是用于分离针对相同类型的全细胞产生的多克隆抗体。 在一个实施方案中,整个细胞是整个细菌细胞。