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公开(公告)号:US11864740B2
公开(公告)日:2024-01-09
申请号:US17888136
申请日:2022-08-15
申请人: NextGen Jane, Inc.
发明人: Ridhi Tariyal , Stephen K. Gire
IPC分类号: A61B10/00 , B01L3/00 , C12Q1/6806 , A61B10/02 , A01N1/02 , C12Q1/6883 , C12Q1/04 , C12M1/30 , G01N1/02
CPC分类号: A61B10/0045 , A61B10/0096 , B01L3/00 , B01L3/5029 , B01L3/523 , C12Q1/6806 , A01N1/021 , A61B2010/0006 , A61B2010/0074 , A61B2010/0216 , B01L2200/0621 , B01L2200/16 , B01L2300/069 , B01L2300/0832 , B01L2300/0851 , B01L2400/0683 , C12M33/02 , C12Q1/04 , C12Q1/6883 , C12Q2600/158 , G01N2001/028
摘要: The present disclosure provides systems, methods, devices, and kits for analysis of vaginal biological samples. A device for the analysis of vaginal biological samples can include a sample collector, an extractor, and an assay cartridge. A method for the analysis of vaginal biological samples can include detecting the presence or absence of a pathology, a disease, an immune disorder, a reproductive disorder of a subject. The method may further comprise preserving, storing, or transporting the vaginal biological samples. A kit for the analysis of vaginal biological samples can include probe, reagents and instructions for detecting a nucleic acid in the vaginal biological samples.
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公开(公告)号:US20180242957A1
公开(公告)日:2018-08-30
申请号:US15881370
申请日:2018-01-26
申请人: NEXTGEN JANE, INC.
发明人: Ridhi TARIYAL , Stephen K. GIRE
IPC分类号: A61B10/00 , A61B5/00 , A61B10/02 , A61F13/20 , A61M39/24 , A61B5/157 , A61B5/15 , A61M1/00 , A61F13/472
CPC分类号: A61B10/0045 , A61B5/150358 , A61B5/150755 , A61B5/157 , A61B5/4362 , A61B5/7282 , A61B10/0058 , A61B10/0096 , A61B10/0291 , A61B2010/0074 , A61B2010/008 , A61B2010/0208 , A61B2010/0216 , A61F13/2045 , A61F13/472 , A61M1/0056 , A61M39/24
摘要: A system for analysis of biological samples may comprise a sample collector and an extractor. The extractor may comprise a sample receptacle configured to receive the sample collector. The extractor may comprise a reservoir in fluid communication with the sample receptacle, the reservoir receiving the biological sample from the sample collector.
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公开(公告)号:US20230257698A1
公开(公告)日:2023-08-17
申请号:US18014568
申请日:2021-07-06
申请人: NextGen Jane, Inc.
发明人: Stephen GIRE , Ridhi TARIYAL , Alain MIR
CPC分类号: C12N5/0605 , A61B10/02 , C12N2500/60
摘要: Provided herein are compositions comprising populations of cells obtained from a pregnant subject comprising at least one of a Hofbauer cell, a cytotrophoblast, a syncytiotrophoblast, an extravillous trophoblast, a villous core stroma, or a fetal vascular cell; a stabilization buffer, wherein the stabilization buffer comprises a preservative; and a cellulosic collection device, wherein at least a subset of the population of cells are intact and inviable and methods of making and using such compositions.
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公开(公告)号:US20230064804A1
公开(公告)日:2023-03-02
申请号:US17888136
申请日:2022-08-15
申请人: NextGen Jane, Inc.
发明人: Ridhi TARIYAL , Stephen K. GIRE
IPC分类号: A61B10/00 , B01L3/00 , C12Q1/6806 , A61B10/02 , A01N1/02 , C12Q1/6883 , C12Q1/04 , C12M1/30 , G01N1/02
摘要: The present disclosure provides systems, methods, devices, and kits for analysis of vaginal biological samples. A device for the analysis of vaginal biological samples can include a sample collector, an extractor, and an assay cartridge. A method for the analysis of vaginal biological samples can include detecting the presence or absence of a pathology, a disease, an immune disorder, a reproductive disorder of a subject. The method may further comprise preserving, storing, or transporting the vaginal biological samples. A kit for the analysis of vaginal biological samples can include probe, reagents and instructions for detecting a nucleic acid in the vaginal biological samples.
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公开(公告)号:US11446011B2
公开(公告)日:2022-09-20
申请号:US16153389
申请日:2018-10-05
申请人: NEXTGEN JANE, INC.
发明人: Ridhi Tariyal , Stephen K. Gire
IPC分类号: A61B10/00 , C12Q1/6806 , B01L3/00 , A01N1/02 , A61B10/02 , C12M1/30 , C12Q1/04 , C12Q1/6883 , G01N1/02
摘要: The present disclosure provides systems, methods, devices, and kits for analysis of vaginal biological samples. A device for the analysis of vaginal biological samples can include a sample collector, an extractor, and an assay cartridge. A method for the analysis of vaginal biological samples can include detecting the presence or absence of a pathology, a disease, an immune disorder, a reproductive disorder of a subject. The method may further comprise preserving, storing, or transporting the vaginal biological samples. A kit for the analysis of vaginal biological samples can include probe, reagents and instructions for detecting a nucleic acid in the vaginal biological samples.
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公开(公告)号:US09918702B2
公开(公告)日:2018-03-20
申请号:US15203464
申请日:2016-07-06
申请人: NEXTGEN JANE, INC.
发明人: Ridhi Tariyal , Stephen Gire
IPC分类号: A61B5/00 , A61B10/00 , A61B10/02 , A61B5/15 , A61B5/157 , A61F13/20 , A61F13/472 , A61M1/00 , A61M39/24
CPC分类号: A61B10/0045 , A61B5/150358 , A61B5/150755 , A61B5/157 , A61B5/4362 , A61B5/7282 , A61B10/0058 , A61B10/0096 , A61B10/0291 , A61B2010/0074 , A61B2010/008 , A61B2010/0208 , A61B2010/0216 , A61F13/2045 , A61F13/472 , A61M1/0056 , A61M39/24
摘要: A medical kit for analysis of vaginal biological samples includes a sample collector, an extractor, and an assay cartridge. The sample collector is compressible and insertable in a vaginal canal for collecting biological samples, and includes a cup-shaped head configured to cradle a cervical os. The extractor includes a sample receptacle configured to receive the sample collector via an open end. The extractor includes a compression mechanism with a compression element that is movable inwards into the open end of the sample receptacle to apply a compression force in response to activation of a release element. The extractor further includes a reservoir in fluid communication with the sample receptacle, the reservoir receiving the biological samples from the sample collector in response to the compression force being applied within the sample receptacle. The assay cartridge has a docking mechanism configured to fluidly communicate with the reservoir of the extractor.
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公开(公告)号:US20240041439A1
公开(公告)日:2024-02-08
申请号:US18258714
申请日:2021-12-21
申请人: NextGen Jane, Inc.
发明人: Ridhi TARIYAL , Stephen GIRE , Adrienne CLARK , Sarah BUSH , Remi Ana GODINEZ
CPC分类号: A61B10/0045 , B01L3/5029 , B01L2300/042 , B01L2300/0672 , B01L2400/0677 , B01L2200/16 , A61B2010/0074
摘要: Provided are systems and methods for preserving a cervico-vaginal fluid sample.
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公开(公告)号:US20190125316A1
公开(公告)日:2019-05-02
申请号:US16153389
申请日:2018-10-05
申请人: NEXTGEN JANE, INC.
发明人: Ridhi TARIYAL , Stephen K. GIRE
IPC分类号: A61B10/00 , C12Q1/6806
摘要: The present disclosure provides systems, methods, devices, and kits for analysis of vaginal biological samples. A device for the analysis of vaginal biological samples can include a sample collector, an extractor, and an assay cartridge. A method for the analysis of vaginal biological samples can include detecting the presence or absence of a pathology, a disease, an immune disorder, a reproductive disorder of a subject. The method may further comprise preserving, storing, or transporting the vaginal biological samples. A kit for the analysis of vaginal biological samples can include probe, reagents and instructions for detecting a nucleic acid in the vaginal biological samples.
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公开(公告)号:US20240268797A1
公开(公告)日:2024-08-15
申请号:US18507494
申请日:2023-11-13
申请人: NextGen Jane, Inc.
发明人: Ridhi TARIYAL , Stephen K. GIRE
IPC分类号: A61B10/00 , A01N1/02 , A61B10/02 , B01L3/00 , C12M1/30 , C12Q1/04 , C12Q1/6806 , C12Q1/6883 , G01N1/02
CPC分类号: A61B10/0045 , A61B10/0096 , B01L3/00 , B01L3/5029 , B01L3/523 , C12Q1/6806 , A01N1/021 , A61B2010/0006 , A61B2010/0074 , A61B2010/0216 , B01L2200/0621 , B01L2200/16 , B01L2300/069 , B01L2300/0832 , B01L2300/0851 , B01L2400/0683 , C12M33/02 , C12Q1/04 , C12Q1/6883 , C12Q2600/158 , G01N2001/028
摘要: The present disclosure provides systems, methods, devices, and kits for analysis of vaginal biological samples. A device for the analysis of vaginal biological samples can include a sample collector, an extractor, and an assay cartridge. A method for the analysis of vaginal biological samples can include detecting the presence or absence of a pathology, a disease, an immune disorder, a reproductive disorder of a subject. The method may further comprise preserving, storing, or transporting the vaginal biological samples. A kit for the analysis of vaginal biological samples can include probe, reagents and instructions for detecting a nucleic acid in the vaginal biological samples.
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公开(公告)号:US20230017064A1
公开(公告)日:2023-01-19
申请号:US17772832
申请日:2020-10-30
申请人: NextGen Jane, Inc.
发明人: Ridhi TARIYAL , Stephen GIRE , Sarah BUSH , Margaret EISEN , Maya LATHI
摘要: Provided herein are methods for detecting a menstrual cycle disorder. Menstrual cycle disorders is detected through analysis of a property of a collected menstrual fluid sample, such as gene expression, flow rate, protein content, nucleic acid content, biomarkers, or other properties.
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