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公开(公告)号：US4385017A
公开(公告)日：1983-05-24
申请号：US273306
申请日：1981-06-15
申请人： Yasushi Joh , Masahiro Yamazaki , Noriaki Kaneko , Shigehiko Oikawa , Yoshihiro Makuta , Chizuko Hayashi
发明人： Yasushi Joh , Masahiro Yamazaki , Noriaki Kaneko , Shigehiko Oikawa , Yoshihiro Makuta , Chizuko Hayashi
CPC分类号： B01D71/42 , B01D63/021 , B01D71/12 , B01D71/30 , D01D5/24 , Y10T428/2975
摘要： A method of manufacturing a microporous hollow fiber having a high permeability to water characterized in that a spinning solution of (A) polyacrylonitrile, (B) an acrylonitrile copolymer, or (C) an admixture of (A) and (B) in an organic solvent is extruded from an annular slit, while simultaneously extruding an organic core liquid which is a solvent for (A), (B) and (C) or a swelling agent capable of swelling them from an orifice encircled by the annular slit and introducing the extruded spinning solution with the core liquid into an aqueous coagulating bath to coagulate the spinning solution to form the hollow fiber.
摘要翻译： 一种具有高渗透性的微孔中空纤维的制造方法，其特征在于：（A）聚丙烯腈，（B）丙烯腈共聚物或（C）（A）和（B）的混合物的有机溶剂 溶剂从环形狭缝挤出，同时挤出作为（A），（B）和（C）的溶剂的有机芯液或能够从由环形狭缝包围的孔中膨胀的溶胀剂，并引入 将具有核心液体的挤出纺丝溶液加入到水性凝固浴中以使纺丝溶液凝结以形成中空纤维。
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公开(公告)号：US5549664A
公开(公告)日：1996-08-27
申请号：US236694
申请日：1994-05-02
CPC分类号： A61L27/56 , A61F2/06 , A61L27/28 , A61L27/48 , A61L27/507
摘要： An artificial blood vessel which has excellent long-term patency and can be used stably in a living body for a long time. The artificial blood vessel has improved durability under pulsation and can withstand puncturing. The artificial blood vessel is made of an elastomer containing a multiplicity of cells throughout the structure thereof and comprises a layer (A) containing closed cells having no communicability therebetween; and a layer (B) containing open cells having mutual communicability therebetween. The surface of the layer (B) which is contiguous to the inner surface of the layer (A) and the wall surfaces of the open cells are coated with a thin film of crosslinked protein of biological origin. The layer (A) may be incorporated with a knitted or woven fabric which is not degradable in a living body. The layer (B) may further contain a synthetic resin short fiber distributed throughout the layer.
摘要翻译： 一种人造血管，具有优异的长期通畅性，可长期稳定地用于生物体。 人造血管在脉动下具有改善的耐久性并且可以承受穿刺。 人造血管由其整个结构中含有多个细胞的弹性体制成，并且包括含有闭孔的层（A），其间没有通信性; 以及包含其间具有相互通信性的开放细胞的层（B）。 与层（A）的内表面邻接的层（B）的表面和开孔的壁表面涂覆有生物来源的交联蛋白质的薄膜。 层（A）可以与在生物体中不可降解的针织或机织织物结合。 层（B）还可以包含分布在整个层中的合成树脂短纤维。
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公开(公告)号：US5202805A
公开(公告)日：1993-04-13
申请号：US650375
申请日：1991-01-30
摘要： The rotary magnetic head apparatus of this invention exhibits an optimum transfer characteristic similar to that in the conventional apparatuses even when the number of coil turns for the magnetic head is reduced to 10 or less. This is achieved by setting the number of secondary winding turns for the rotary transformer to 16 or less and by setting the number of primary winding turns for the rotary transformer in such a way that a product of a step-up ratio--defined as the number of secondary winding turns divided by the number of primary winding turns--and the number of coil turns will be around 50. This reduction in the number of turns of coil on the magnetic head, from 20 or 25 with the conventional apparatus to less than 10, results in a substantial reduction in the cost of magnetic head and therefore the rotary magnetic head apparatus.
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公开(公告)号：US4822352A
公开(公告)日：1989-04-18
申请号：US66849
申请日：1987-06-25
申请人： Yasushi Joh , Noriaki Kaneko
发明人： Yasushi Joh , Noriaki Kaneko
CPC分类号： C08G18/4854 , A61F2/06 , A61L27/18 , A61L27/56 , B29C67/24 , C08G18/10 , B29C47/00 , B29C47/0023 , B29K2075/00 , B29K2995/0088 , B29L2031/7534
摘要： Disclosed is a medical tube comprising a mono-layer medical tube comprising a high molecular weight compound, wherein the inner texture of a tube wall constituting the tube is porous and no skin layer is present on the inner face of the tube wall.The porous inner texture of the tube is microscopically spongy and contains cells or voids interconnected by pores. The inner wall of the tube contains concavities which open into the cells or voids and communicates them with any fluid flowing through the tube.Disclosed is also a process for producing a medical tube, comprising thrusting forward a core rod having a round cross-section and made of a rigid body from a circular orifice to extrude a solution of a high molecular weight compound from a gap slit defined between the orifice and the core rod in such a manner that the solution is spread over the whole surface of the core rod, and leading the core rod in a solidifying medium to solidify the high molecular weight compound around the core rod, followed by taking out the core rod.The medical tubes of this invention or the medical tubes produced by the present process has excellent compatibility with blood, particularly is suitable for an artificial blood vessel which is required to have excellent long term patency.
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5.发明授权Stable polymer emulsion composition capable of giving a thromboresistant surface, and process for production thereof 失效能够产生抗血栓表面的稳定的聚合物乳液组合物及其生产方法
公开(公告)号：US4604412A
公开(公告)日：1986-08-05
申请号：US475499
申请日：1983-03-15
申请人： Yasushi Joh , Toshio Nagase , Noriaki Kaneko
发明人： Yasushi Joh , Toshio Nagase , Noriaki Kaneko
IPC分类号： C08G18/00 , A61L33/00 , A61L33/06 , C08L75/00 , C08L75/04 , C08L83/04 , C08L83/06 , C09D5/00 , C09K3/00
CPC分类号： A61L33/062 , C08L75/04 , Y10S525/903
摘要： A stable polymer emulsion composition capable of giving a thromboresistant surface, said composition comprising polyurethane, a polydiorganosiloxane, and a cyclic ether, said polydiorganosiloxane being dispersed as particles having an average particle diameter of 0.1 to 50 microns in a solution of the polyurethane in the cyclic ether, and at least a part of the surfaces of said particles being crosslinked. The said composition can be prepared by dispersing a polydiorganosiloxane having a hydroxyl or acetate end group as fine particles in a solution of polyurethane in a cyclic ether to form an emulsion, and reacting the polydiorganosiloxane with a crosslinking agent to crosslink at least a part of the surfaces of the particles in the presence of 10 to 500 ppm of water.
摘要翻译： 所述组合物包含聚氨酯，聚二有机硅氧烷和环醚，所述聚二有机硅氧烷在平均粒径为0.1-50微米的颗粒中分散在聚氨酯在环状 醚，并且所述颗粒的至少一部分表面是交联的。 所述组合物可以通过将具有羟基或乙酸酯端基的聚二有机硅氧烷作为细颗粒分散在聚氨酯在环醚中的溶液中以形成乳液，并使聚二有机硅氧烷与交联剂反应以使至少一部分 在10至500ppm水存在下颗粒的表面。
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6.发明授权Method and apparatus for removing gas from interior of hollow-fiber permeability apparatus 失效从中空纤维透气装置内部除去气体的方法和装置
公开(公告)号：US4108764A
公开(公告)日：1978-08-22
申请号：US797765
申请日：1977-05-17
申请人： Noriaki Kaneko , Yasushi Joh
发明人： Noriaki Kaneko , Yasushi Joh
CPC分类号： B01D63/021 , A61M1/3643 , B01D65/00
摘要： In a method and apparatus for removing gas from the interior of a hollow-fiber permeability apparatus in which a permeating region of a housing contains a bundle of hollow fibers, and materials can selectively permeate through the membranes formed by the permeable walls of the hollow fibers, between first and second fluids flowing through the housing inside and outside the fibers respectively, at least one of first and second materials to produce carbonic acid gas by mutual chemical reaction is contained in a flow path for the first fluid and/or another flow path for the second fluid, and the first and second materials react with each other in at least one part of the apparatus to produce carbonic acid gas, whereby the gas previously existing in the interior of the housing is substituted with the produced carbonic acid gas.
摘要翻译： 在用于从中空纤维透气装置的内部除去气体的方法和装置中，其中壳体的渗透区域包含一束中空纤维，并且材料可以选择地渗透通过中空纤维的可渗透壁形成的膜 在分别在纤维内部和外部流过第一和第二流体之间，通过相互化学反应产生碳酸气体的第一和第二材料中的至少一种被包含在用于第一流体和/或另一个流动路径的流动路径中 对于第二流体，并且第一和第二材料在装置的至少一部分中彼此反应以产生碳酸气体，由此先前存在于壳体内部的气体被产生的碳酸气体代替。
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公开(公告)号：US4995799A
公开(公告)日：1991-02-26
申请号：US258351
申请日：1988-10-17
申请人： Ryutaro Hayashi , Noriaki Kaneko
发明人： Ryutaro Hayashi , Noriaki Kaneko
IPC分类号： B29C43/20 , B29C35/08 , B29C43/02 , B29C43/18 , B29C43/32 , B29C70/78 , B29D17/00 , B29L17/00 , G11B3/70 , G11B7/26
CPC分类号： B29D17/005 , B29C43/021 , B29C43/18 , B29C70/78 , G11B7/26 , B29C2035/0827 , B29L2017/005 , Y10S425/81
摘要： Disclosed herein is an apparatus for manufacturing an optical substrate which has a transfer layer corresponding to an optical pattern by supplying a liquid radiation-setting resin between a stamper carrying the optical pattern and the substrate and by setting the radiation-setting resin. The apparatus includes a turnable, a center boss, gas pressure control mean, and a defoaming means including an outer circumferential means to defoam the radiation-setting resin. The turnable, the center boss and the gas pressure control means are united into a carriage base which is movable on the casing of the apparatus.
摘要翻译： 本发明公开了一种光学基板的制造装置，其具有与光学图案对应的转印层，通过在承载光学图案的基板与基板之间供给液体辐射固化树脂，并设置放射线固化树脂。 该装置包括可转动的中心凸起，气体压力控制装置和包括用于消除辐射固化树脂的外周装置的消泡装置。 可转动的中心凸台和气体压力控制装置结合到可在设备的壳体上移动的滑架基座。
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8.发明授权
公开(公告)号：US5693320A
公开(公告)日：1997-12-02
申请号：US614016
申请日：1996-03-12
申请人： Masamune Sakai , Hiroyuki Ikeda , Noriaki Kaneko , Yutaka Tamura
发明人： Masamune Sakai , Hiroyuki Ikeda , Noriaki Kaneko , Yutaka Tamura
IPC分类号： C07C233/55 , C08F20/30 , C08F20/58 , C07C229/00 , C08F20/18 , C08K5/01
CPC分类号： C08F20/30 , C07C233/55 , C08F20/58
摘要： Novel acetylsalicylic acid derivatives having general formula (I) are provided, in which R.sup.1 is hydrogen or methyl; R.sup.2 is --O-- or --NH--; and W is hydroxy, halogen, lower alkoxy, lower alkenyloxy, lower alkynyloxy, cycloalkyloxy, aryloxy, aralkyloxy, acyloxy, or --N(R.sup.3)(R.sup.4) wherein the lower alkoxy, the lower alkenyloxy, the lower alkynyloxy, the cycloalkyloxy, the aryloxy, the aralkyloxy, and the acyloxy are optionally substituted with hydroxy, carboxyl, lower alkoxy, lower alkyl, halogen, nitro, and amino. The invention also pertains to a polymer made from such derivatives and a medical equipment containing the polymer. The polymer is useful in the prevention of platelet aggregation thereon. ##STR1##
摘要翻译： 提供了具有通式（I）的新型乙酰水杨酸衍生物，其中R 1是氢或甲基; R2是-O-或-NH-; 并且W是羟基，卤素，低级烷氧基，低级链烯氧基，低级炔氧基，环烷氧基，芳氧基，芳烷氧基，酰氧基或-N（R3）（R4），其中低级烷氧基，低级烯氧基，低级炔氧基，环烷氧基， 芳氧基，芳烷氧基和酰氧基任选被羟基，羧基，低级烷氧基，低级烷基，卤素，硝基和氨基取代。 本发明还涉及由这样的衍生物制成的聚合物和含有聚合物的医疗设备。 聚合物可用于预防血小板聚集。
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公开(公告)号：US4986832A
公开(公告)日：1991-01-22
申请号：US236547
申请日：1988-08-25
摘要： Disclosed is an artificial blood comprising a vessel wall that is comprised of plural layers and is porous as a whole, wherein an innermost layer has open-cell structure in which pores are connected through each other, and has a thickness of not less than 5 .mu.m or more and not more than 2/3 of the thickness of the vessel wall. Also disclosed is a process for preparing an artificial blood vessel, comprising the steps of; solidifying a layer that has been formed on the surface of a rod-like substrate by coating a solution comprising a polymeric compound, followed by desolvation to make a rod; coating a solution having the same composition as the solution comprising a polymeric compound, on the inner surface of the rod, and spraying a powder which is insoluble to the polymeric compound solution thereon; solidifying the polymeric compound solution coated on the inner surface of the rod, followed by desolvation; and removing the powder from the polymeric compound.
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公开(公告)号：US4342711A
公开(公告)日：1982-08-03
申请号：US91491
申请日：1979-11-05
申请人： Yasushi Joh , Masahiro Yamazaki , Noriaki Kaneko , Shigehiko Oikawa , Yoshihiro Makuta , Chizuko Hayashi
发明人： Yasushi Joh , Masahiro Yamazaki , Noriaki Kaneko , Shigehiko Oikawa , Yoshihiro Makuta , Chizuko Hayashi
CPC分类号： B01D71/42 , B01D63/021 , B01D71/12 , B01D71/30 , D01D5/24 , Y10T428/2975
摘要： A method of manufacturing a hollow fiber includes the steps of:extruding a spinning solution of high molecular weight compound dissolved into a solvent, from an annular slit; and simultaneously extruding a liquid consisting of at least one of the solvent and swelling liquid capable of swelling the high molecular weight compound from an orifice encircled by the annular slit.
摘要翻译： 制造中空纤维的方法包括以下步骤：从环形狭缝挤出溶解在溶剂中的高分子量化合物的纺丝溶液; 并且同时挤出由至少一种溶剂和膨胀液体组成的液体，所述液体能够从由环形狭缝包围的孔中膨胀高分子量化合物。
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