公开(公告)号：US4385017A

公开(公告)日：1983-05-24

申请号：US273306

申请日：1981-06-15

申请人： Yasushi Joh ,  Masahiro Yamazaki ,  Noriaki Kaneko ,  Shigehiko Oikawa ,  Yoshihiro Makuta ,  Chizuko Hayashi

发明人： Yasushi Joh ,  Masahiro Yamazaki ,  Noriaki Kaneko ,  Shigehiko Oikawa ,  Yoshihiro Makuta ,  Chizuko Hayashi

IPC分类号： D01D5/24 ,  D01F1/08 ,  D01F8/08 ,  B29D27/00

CPC分类号： B01D71/42 ,  B01D63/021 ,  B01D71/12 ,  B01D71/30 ,  D01D5/24 ,  Y10T428/2975

摘要： A method of manufacturing a microporous hollow fiber having a high permeability to water characterized in that a spinning solution of (A) polyacrylonitrile, (B) an acrylonitrile copolymer, or (C) an admixture of (A) and (B) in an organic solvent is extruded from an annular slit, while simultaneously extruding an organic core liquid which is a solvent for (A), (B) and (C) or a swelling agent capable of swelling them from an orifice encircled by the annular slit and introducing the extruded spinning solution with the core liquid into an aqueous coagulating bath to coagulate the spinning solution to form the hollow fiber.

摘要翻译： 一种具有高渗透性的微孔中空纤维的制造方法，其特征在于：（A）聚丙烯腈，（B）丙烯腈共聚物或（C）（A）和（B）的混合物的有机溶剂 溶剂从环形狭缝挤出，同时挤出作为（A），（B）和（C）的溶剂的有机芯液或能够从由环形狭缝包围的孔中膨胀的溶胀剂，并引入 将具有核心液体的挤出纺丝溶液加入到水性凝固浴中以使纺丝溶液凝结以形成中空纤维。

公开(公告)号：US4342711A

公开(公告)日：1982-08-03

申请号：US91491

申请日：1979-11-05

申请人： Yasushi Joh ,  Masahiro Yamazaki ,  Noriaki Kaneko ,  Shigehiko Oikawa ,  Yoshihiro Makuta ,  Chizuko Hayashi

发明人： Yasushi Joh ,  Masahiro Yamazaki ,  Noriaki Kaneko ,  Shigehiko Oikawa ,  Yoshihiro Makuta ,  Chizuko Hayashi

IPC分类号： D01D5/24 ,  D01F1/08 ,  B29D27/00

CPC分类号： B01D71/42 ,  B01D63/021 ,  B01D71/12 ,  B01D71/30 ,  D01D5/24 ,  Y10T428/2975

摘要： A method of manufacturing a hollow fiber includes the steps of:extruding a spinning solution of high molecular weight compound dissolved into a solvent, from an annular slit; and simultaneously extruding a liquid consisting of at least one of the solvent and swelling liquid capable of swelling the high molecular weight compound from an orifice encircled by the annular slit.

摘要翻译： 制造中空纤维的方法包括以下步骤：从环形狭缝挤出溶解在溶剂中的高分子量化合物的纺丝溶液; 并且同时挤出由至少一种溶剂和膨胀液体组成的液体，所述液体能够从由环形狭缝包围的孔中膨胀高分子量化合物。

公开(公告)号：US4508535A

公开(公告)日：1985-04-02

申请号：US483138

申请日：1983-04-08

申请人： Yasushi Joh ,  Noriaki Kaneko ,  Toshio Nagase

发明人： Yasushi Joh ,  Noriaki Kaneko ,  Toshio Nagase

IPC分类号： A61M1/10 ,  A61M1/12 ,  A61M1/36 ,  A61M25/00 ,  A61M39/10

CPC分类号： A61M1/10 ,  A61M1/1008 ,  A61M1/122 ,  A61M1/3659 ,  A61M1/106 ,  A61M25/0041

摘要： The invention relates to a tubular cannula for use with an artificial heart in open heart surgery.The cannula has a tubular portion with an axis having a three-dimensional configuration by being bent at least twice in different directions between an insertion distal end tip for insertion into a heart and a connection proximal end tip for connection with the artificial heart.

摘要翻译： 本发明涉及一种用于心脏开放心脏手术中人造心脏的管状插管。 插管具有管状部分，其轴线具有三维构型，通过在用于插入心脏的插入远端末端和用于与人造心脏连接的连接近端尖端之间沿不同方向弯曲至少两次。

公开(公告)号：US4284594A

公开(公告)日：1981-08-18

申请号：US102537

申请日：1979-12-11

申请人： Yasushi Joh ,  Akihiko Niina ,  Noriaki Kaneko ,  Toshio Sano ,  Noriyuki Ichige ,  Koji Ichikawa ,  Akira Fukutome ,  Hisako Sonobe

发明人： Yasushi Joh ,  Akihiko Niina ,  Noriaki Kaneko ,  Toshio Sano ,  Noriyuki Ichige ,  Koji Ichikawa ,  Akira Fukutome ,  Hisako Sonobe

IPC分类号： A61M1/18 ,  B01D71/06 ,  D01D5/24 ,  D01F1/08 ,  D01F2/28 ,  B29D27/00

CPC分类号： B01D69/087 ,  B01D67/0016 ,  B01D71/14 ,  D01D5/24 ,  D01F2/28 ,  Y10T428/2975

摘要： A method of manufacturing a hollow fiber in which a spinning solution of cellulose ester dissolved into an organic solvent is extruded from an annular slit, and simultaneously a core liquid is introduced into the inside hollow portion of the extruded spinning solution, the core liquid being selected from the group of hydroxycarboxylic acid, derivative of hydroxycarboxylic acid, monoterpene or these mixture, or consisting of a solution of the above-described compound or mixture.

摘要翻译： 一种中空纤维的制造方法，其中将纤维素酯的纺丝溶液从环状狭缝中挤出，同时将芯液引入挤压纺丝溶液的内部中空部分，选择芯液 由羟基羧酸，羟基羧酸衍生物，单萜或这些混合物组成，或由上述化合物或混合物的溶液组成。

公开(公告)号：US4237013A

公开(公告)日：1980-12-02

申请号：US21885

申请日：1979-03-19

申请人： Masahiro Yamazaki ,  Yoshihiro Makuta ,  Yasushi Joh ,  Noriaki Kaneko

发明人： Masahiro Yamazaki ,  Yoshihiro Makuta ,  Yasushi Joh ,  Noriaki Kaneko

IPC分类号： A61M1/18 ,  B01D63/02 ,  B01D31/00

CPC分类号： B01D63/02

摘要： A hollow-fiber permeability apparatus includes a housing having a permeating region, a bundle of permeable-wall hollow fibers in the permeating region, means for supplying a first fluid flowing between the exteriors of the fibers, another means for passing a second fluid through the interiors of fibers such that materials selectively permeate through the walls of the fibers, and an enlarged cross-section portion to define at least one compartment between the bundle and a wall of the housing and having an inlet opening for introducing the first fluid into the housing, the permeating region having a flattened cross-section in the direction substantially perpendicular to the lengthwise direction of the fibers, and the enlarged cross-section portion being formed at least along substantially the whole lengths of the longer side of the cross section of the permeating region.

摘要翻译： 中空纤维透气装置包括具有渗透区域的壳体，渗透区域中的一层可渗透壁中空纤维，用于供应在纤维外部之间流动的第一流体的装置，用于使第二流体通过 纤维的内部，使得材料选择性地渗透通过纤维的壁，以及扩大的横截面部分，以在束和壳体的壁之间限定至少一个隔室，并具有用于将第一流体引入壳体 所述渗透区域在与所述纤维的长度方向大致垂直的方向上具有扁平的横截面，并且所述扩大的横截面部分至少沿着渗透层的横截面的长边的大致整个长度形成 地区。

公开(公告)号：US4822352A

公开(公告)日：1989-04-18

申请号：US66849

申请日：1987-06-25

申请人： Yasushi Joh ,  Noriaki Kaneko

发明人： Yasushi Joh ,  Noriaki Kaneko

IPC分类号： A61F2/06 ,  A61L27/18 ,  A61L27/56 ,  B29C47/00 ,  B29C67/24 ,  C08G18/10 ,  C08G18/48

CPC分类号： C08G18/4854 ,  A61F2/06 ,  A61L27/18 ,  A61L27/56 ,  B29C67/24 ,  C08G18/10 ,  B29C47/00 ,  B29C47/0023 ,  B29K2075/00 ,  B29K2995/0088 ,  B29L2031/7534

摘要： Disclosed is a medical tube comprising a mono-layer medical tube comprising a high molecular weight compound, wherein the inner texture of a tube wall constituting the tube is porous and no skin layer is present on the inner face of the tube wall.The porous inner texture of the tube is microscopically spongy and contains cells or voids interconnected by pores. The inner wall of the tube contains concavities which open into the cells or voids and communicates them with any fluid flowing through the tube.Disclosed is also a process for producing a medical tube, comprising thrusting forward a core rod having a round cross-section and made of a rigid body from a circular orifice to extrude a solution of a high molecular weight compound from a gap slit defined between the orifice and the core rod in such a manner that the solution is spread over the whole surface of the core rod, and leading the core rod in a solidifying medium to solidify the high molecular weight compound around the core rod, followed by taking out the core rod.The medical tubes of this invention or the medical tubes produced by the present process has excellent compatibility with blood, particularly is suitable for an artificial blood vessel which is required to have excellent long term patency.

公开(公告)号：US4604412A

公开(公告)日：1986-08-05

申请号：US475499

申请日：1983-03-15

申请人： Yasushi Joh ,  Toshio Nagase ,  Noriaki Kaneko

发明人： Yasushi Joh ,  Toshio Nagase ,  Noriaki Kaneko

IPC分类号： C08G18/00 ,  A61L33/00 ,  A61L33/06 ,  C08L75/00 ,  C08L75/04 ,  C08L83/04 ,  C08L83/06 ,  C09D5/00 ,  C09K3/00

CPC分类号： A61L33/062 ,  C08L75/04 ,  Y10S525/903

摘要： A stable polymer emulsion composition capable of giving a thromboresistant surface, said composition comprising polyurethane, a polydiorganosiloxane, and a cyclic ether, said polydiorganosiloxane being dispersed as particles having an average particle diameter of 0.1 to 50 microns in a solution of the polyurethane in the cyclic ether, and at least a part of the surfaces of said particles being crosslinked. The said composition can be prepared by dispersing a polydiorganosiloxane having a hydroxyl or acetate end group as fine particles in a solution of polyurethane in a cyclic ether to form an emulsion, and reacting the polydiorganosiloxane with a crosslinking agent to crosslink at least a part of the surfaces of the particles in the presence of 10 to 500 ppm of water.

摘要翻译： 所述组合物包含聚氨酯，聚二有机硅氧烷和环醚，所述聚二有机硅氧烷在平均粒径为0.1-50微米的颗粒中分散在聚氨酯在环状 醚，并且所述颗粒的至少一部分表面是交联的。 所述组合物可以通过将具有羟基或乙酸酯端基的聚二有机硅氧烷作为细颗粒分散在聚氨酯在环醚中的溶液中以形成乳液，并使聚二有机硅氧烷与交联剂反应以使至少一部分 在10至500ppm水存在下颗粒的表面。

公开(公告)号：US4108764A

公开(公告)日：1978-08-22

申请号：US797765

申请日：1977-05-17

申请人： Noriaki Kaneko ,  Yasushi Joh

发明人： Noriaki Kaneko ,  Yasushi Joh

IPC分类号： A61M1/14 ,  A61M1/36 ,  B01D63/02 ,  B01D65/00 ,  B01D13/00

CPC分类号： B01D63/021 ,  A61M1/3643 ,  B01D65/00

摘要： In a method and apparatus for removing gas from the interior of a hollow-fiber permeability apparatus in which a permeating region of a housing contains a bundle of hollow fibers, and materials can selectively permeate through the membranes formed by the permeable walls of the hollow fibers, between first and second fluids flowing through the housing inside and outside the fibers respectively, at least one of first and second materials to produce carbonic acid gas by mutual chemical reaction is contained in a flow path for the first fluid and/or another flow path for the second fluid, and the first and second materials react with each other in at least one part of the apparatus to produce carbonic acid gas, whereby the gas previously existing in the interior of the housing is substituted with the produced carbonic acid gas.

摘要翻译： 在用于从中空纤维透气装置的内部除去气体的方法和装置中，其中壳体的渗透区域包含一束中空纤维，并且材料可以选择地渗透通过中空纤维的可渗透壁形成的膜 在分别在纤维内部和外部流过第一和第二流体之间，通过相互化学反应产生碳酸气体的第一和第二材料中的至少一种被包含在用于第一流体和/或另一个流动路径的流动路径中 对于第二流体，并且第一和第二材料在装置的至少一部分中彼此反应以产生碳酸气体，由此先前存在于壳体内部的气体被产生的碳酸气体代替。

公开(公告)号：US4995799A

公开(公告)日：1991-02-26

申请号：US258351

申请日：1988-10-17

申请人： Ryutaro Hayashi ,  Noriaki Kaneko

发明人： Ryutaro Hayashi ,  Noriaki Kaneko

IPC分类号： B29C43/20 ,  B29C35/08 ,  B29C43/02 ,  B29C43/18 ,  B29C43/32 ,  B29C70/78 ,  B29D17/00 ,  B29L17/00 ,  G11B3/70 ,  G11B7/26

CPC分类号： B29D17/005 ,  B29C43/021 ,  B29C43/18 ,  B29C70/78 ,  G11B7/26 ,  B29C2035/0827 ,  B29L2017/005 ,  Y10S425/81

摘要： Disclosed herein is an apparatus for manufacturing an optical substrate which has a transfer layer corresponding to an optical pattern by supplying a liquid radiation-setting resin between a stamper carrying the optical pattern and the substrate and by setting the radiation-setting resin. The apparatus includes a turnable, a center boss, gas pressure control mean, and a defoaming means including an outer circumferential means to defoam the radiation-setting resin. The turnable, the center boss and the gas pressure control means are united into a carriage base which is movable on the casing of the apparatus.

摘要翻译： 本发明公开了一种光学基板的制造装置，其具有与光学图案对应的转印层，通过在承载光学图案的基板与基板之间供给液体辐射固化树脂，并设置放射线固化树脂。 该装置包括可转动的中心凸起，气体压力控制装置和包括用于消除辐射固化树脂的外周装置的消泡装置。 可转动的中心凸台和气体压力控制装置结合到可在设备的壳体上移动的滑架基座。

公开(公告)号：US5693320A

公开(公告)日：1997-12-02

申请号：US614016

申请日：1996-03-12

申请人： Masamune Sakai ,  Hiroyuki Ikeda ,  Noriaki Kaneko ,  Yutaka Tamura

发明人： Masamune Sakai ,  Hiroyuki Ikeda ,  Noriaki Kaneko ,  Yutaka Tamura

IPC分类号： C07C233/55 ,  C08F20/30 ,  C08F20/58 ,  C07C229/00 ,  C08F20/18 ,  C08K5/01

CPC分类号： C08F20/30 ,  C07C233/55 ,  C08F20/58

摘要： Novel acetylsalicylic acid derivatives having general formula (I) are provided, in which R.sup.1 is hydrogen or methyl; R.sup.2 is --O-- or --NH--; and W is hydroxy, halogen, lower alkoxy, lower alkenyloxy, lower alkynyloxy, cycloalkyloxy, aryloxy, aralkyloxy, acyloxy, or --N(R.sup.3)(R.sup.4) wherein the lower alkoxy, the lower alkenyloxy, the lower alkynyloxy, the cycloalkyloxy, the aryloxy, the aralkyloxy, and the acyloxy are optionally substituted with hydroxy, carboxyl, lower alkoxy, lower alkyl, halogen, nitro, and amino. The invention also pertains to a polymer made from such derivatives and a medical equipment containing the polymer. The polymer is useful in the prevention of platelet aggregation thereon. ##STR1##

摘要翻译： 提供了具有通式（I）的新型乙酰水杨酸衍生物，其中R 1是氢或甲基; R2是-O-或-NH-; 并且W是羟基，卤素，低级烷氧基，低级链烯氧基，低级炔氧基，环烷氧基，芳氧基，芳烷氧基，酰氧基或-N（R3）（R4），其中低级烷氧基，低级烯氧基，低级炔氧基，环烷氧基， 芳氧基，芳烷氧基和酰氧基任选被羟基，羧基，低级烷氧基，低级烷基，卤素，硝基和氨基取代。 本发明还涉及由这样的衍生物制成的聚合物和含有聚合物的医疗设备。 聚合物可用于预防血小板聚集。