公开(公告)号：US20090111146A1

公开(公告)日：2009-04-30

申请号：US10570143

申请日：2004-09-02

申请人： Eiko Ohtsuka ,  Yutaka Tamura

发明人： Eiko Ohtsuka ,  Yutaka Tamura

IPC分类号： C12P21/04 ,  C12N15/00 ,  C07K16/18 ,  C12N15/11 ,  C12N5/06

CPC分类号： C07K14/7155 ,  C07K2319/30

摘要： Means for effectively performing therapies at a low cost is provided in which an antibody drug including a fusion protein fusing an extracellular region of IL-10 receptor 1 with a human antibody is used. A gene encoding a fusion protein fusing an extracellular region of IL-10 receptor 1 with a constant region of human IgG1 is incorporated into an expression vector to provide an expression vector for gene therapies and vaccines.

摘要翻译： 提供了以低成本有效进行治疗的方法，其中使用包含融合IL-10受体1的细胞外区域的融合蛋白的抗体药物与人抗体。 将编码融合蛋白质的融合蛋白质融合到表达载体中以提供IL-10受体1的细胞外区域与人IgG1的恒定区域以提供用于基因治疗和疫苗的表达载体。

公开(公告)号：US07208592B2

公开(公告)日：2007-04-24

申请号：US10368391

申请日：2003-02-20

申请人： Naoyuki Kawanishi ,  Kazuhiko Fujiwara ,  Hitoshi Namikawa ,  Takahiro Moto ,  Yutaka Tamura

发明人： Naoyuki Kawanishi ,  Kazuhiko Fujiwara ,  Hitoshi Namikawa ,  Takahiro Moto ,  Yutaka Tamura

IPC分类号： C08B3/00 ,  C08B5/00 ,  C07H1/00

CPC分类号： C08B3/24

摘要： A process for alkali saponification of polymer film is disclosed. The process comprises the steps of applying solution of an alkali onto a polymer film having a temperature of not lower than room temperature, and washing away the alkaline solution from the film.

摘要翻译： 公开了一种聚合物薄膜的碱皂化方法。 该方法包括以下步骤：将碱溶液施加到温度不低于室温的聚合物膜上，并从该膜上洗涤碱性溶液。

公开(公告)号：US5302501A

公开(公告)日：1994-04-12

申请号：US966383

申请日：1992-10-26

申请人： Yutaka Tamura ,  Yasuyuki Takagi ,  Junichi Yamanouchi

发明人： Yutaka Tamura ,  Yasuyuki Takagi ,  Junichi Yamanouchi

IPC分类号： G03C1/005 ,  G03C1/053 ,  G03C1/76

CPC分类号： G03C1/7614 ,  G03C1/0051 ,  G03C1/053 ,  Y10S430/164

摘要： A silver halide photographic material comprising a support having thereon at least one silver halide emulsion layer, wherein the swelling ratio of the entire hydrophilic colloid layers on the acid polymer-containing layer side of the support of the silver halide photographic material having a hydrophilic colloid layer containing at least one acid polymer (having a carboxyl group-containing monomer unit content of at least 15 mol % or an acid value of at least 1.5 meq/g) on at least one silver halide emulsion layer-coated side thereof is at least 200% in distilled water, said acid polymer being dissolved in water and added to said hydrophilic colloid layer, and the swollen thickness of the above entire hydrophilic colloid layers at the time of the completion of the rinsing stage is not more than 8 .mu.m when said silver halide photographic material is processed (the swelling ratio in distilled water is a value obtained by incubating the photographic material at 40.degree. C. and 60% RH (percent relative humidity) for 16 hours, immersing it in distilled water at 21.degree. C. for 3 minutes and measuring the change of the thickness thereof).

摘要翻译： 一种卤化银照相材料，包括其上具有至少一个卤化银乳剂层的载体，其中具有亲水胶体层的卤化银照相材料的载体的含酸性聚合物层层上的整个亲水胶体层的溶胀比 含有至少一种酸性聚合物（具有含羧基的单体单元含量为至少15mol％或酸值至少为1.5meq / g）在至少一个卤化银乳剂层涂覆侧上为至少200 在蒸馏水中，所述酸性聚合物溶于水中并加入到所述亲水胶体层中，并且在漂洗阶段完成时上述整个亲水胶体层的溶胀厚度不大于8（m） 当所述卤化银照相材料被处理时（蒸馏水中的溶胀比是通过将照相材料在40℃和60％RH下温育获得的值 （相对湿度百分比）16小时，将其浸入21℃的蒸馏水中3分钟并测量其厚度变化）。

公开(公告)号：US5225508A

公开(公告)日：1993-07-06

申请号：US710447

申请日：1991-06-05

申请人： Yutaka Tamura ,  Fumie Watari

发明人： Yutaka Tamura ,  Fumie Watari

IPC分类号： C07C321/20 ,  C07C321/28 ,  C08F12/34 ,  G02B1/04

CPC分类号： C08F12/34 ,  C07C321/20 ,  C07C321/28 ,  G02B1/04

摘要： Disclosed are a diethylenicallyunsaturated monomer represented by the following formula [Ia]: ##STR1## wherein n is an integer of from 1 to 10, and a and b each represent 0 or an integer of from 1 to 4,and an optical resin which is substantially insoluble and infusible and has a refractive index .eta..sub.D of at least 1.62, and which is obtained by polymerizing a monomer comprising 50 to 100% by weight of this diethylenically unsaturated monomer.

摘要翻译： 公开了由下式[Ia]表示的二烯类不饱和单体：其中n为1〜10的整数，a和b各自表示0或1〜4的整数， 树脂，其基本上不溶和不熔，折射率ηD至少为1.62，其通过聚合包含50-100重量％的该烯键式不饱和单体的单体而获得。

公开(公告)号：US4536605A

公开(公告)日：1985-08-20

申请号：US371424

申请日：1982-04-23

申请人： Koichi Kida ,  Yoshio Kawai ,  Yutaka Tamura ,  Yoshiharu Suzuki

发明人： Koichi Kida ,  Yoshio Kawai ,  Yutaka Tamura ,  Yoshiharu Suzuki

IPC分类号： B01J21/12 ,  C07C1/20 ,  C07C1/00

CPC分类号： B01J21/12 ,  C07C1/20 ,  C07C2521/12

摘要： A tertiary olefin is produced by contacting a gaseous tertiary ether usually represented by the following general formula: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are alkyl groups each having 1-4 carbon atoms which may be same or different and R.sup.4 is an alkyl group having 1-3 carbon atoms, with a catalyst obtained by calcining a silica-alumina compound at 700.degree.-1100.degree. C. in order to effect cracking of the tertiary ether. This reaction may be carried out in the presence of steam to result in further improvements.

摘要翻译： 通过与通常由以下通式表示的气态叔醚接触来制备叔烯烃：其中R 1，R 2和R 3是可以相同或不同的1-4个碳原子的烷基，R 4是烷基 具有1-3个碳原子，与通过在700℃-1100℃煅烧二氧化硅 - 氧化铝化合物而获得的催化剂以实现叔乙醚的裂化。 该反应可以在蒸汽存在下进行，以进一步改进。

公开(公告)号：US20130129631A1

公开(公告)日：2013-05-23

申请号：US13700780

申请日：2011-05-31

申请人： Hideki Hayashi ,  Masanori Fujinami ,  Taro Toyota ,  Yutaka Tamura ,  Akira Aoki ,  Yutaka Muraki ,  Kazuki Onoue

发明人： Hideki Hayashi ,  Masanori Fujinami ,  Taro Toyota ,  Yutaka Tamura ,  Akira Aoki ,  Yutaka Muraki ,  Kazuki Onoue

IPC分类号： A61K49/00 ,  C09B23/08

CPC分类号： C09B23/083 ,  A61K9/127 ,  A61K49/0032 ,  A61K49/0034 ,  A61K49/0084 ,  C07D209/60 ,  C09B23/086

摘要： Disclosed is a near-infrared fluorescent imaging agent comprising an indocyanine-based fluorescent dye and a liposome. The near-infrared fluorescent imaging agent of the present invention demonstrates high fluorescence intensity and a long anchoring time in sentinel lymph nodes, thereby making it useful for detecting sentinel lymph nodes in sentinel lymph node navigation surgery. Also disclosed is an indocyanine green derivative that is particularly suitable for use in the near-infrared fluorescent imaging agent of the present invention.

摘要翻译： 公开了包含吲哚菁系荧光染料和脂质体的近红外荧光显影剂。 本发明的近红外荧光显像剂在前哨淋巴结中表现出高荧光强度和长锚定时间，从而可用于检测前哨淋巴结导航手术中的前哨淋巴结。 还公开了特别适用于本发明的近红外荧光显影剂的吲哚菁绿衍生物。

公开(公告)号：US20130063115A1

公开(公告)日：2013-03-14

申请号：US13423567

申请日：2012-03-19

申请人： Yusuke HIKICHI ,  Yutaka Tamura

发明人： Yusuke HIKICHI ,  Yutaka Tamura

IPC分类号： G05F1/10

CPC分类号： G05F1/575

摘要： A constant-voltage power supply circuit includes a first transistor connected between a power supply terminal and an output terminal. The constant-voltage power supply circuit includes a voltage divider circuit including a first resistor having a first end connected to the output terminal and a second resistor having a first end connected to a second end of the first resistor and a second end connected to ground. The constant-voltage power supply circuit includes an output voltage control amplifier that compares the divided voltage and a reference voltage and controls a voltage of a control terminal of the first transistor. The constant-voltage power supply circuit includes a current-limiting characteristic control circuit that controls the voltage of the control terminal of the first transistor according to the divided voltage and an output current.

摘要翻译： 恒压电源电路包括连接在电源端子和输出端子之间的第一晶体管。 恒压电源电路包括分压器电路，该分压器电路包括具有连接到输出端子的第一端的第一电阻器和具有连接到第一电阻器的第二端的第一端和连接到地的第二端的第二电阻器。 恒压电源电路包括输出电压控制放大器，其将分压和参考电压进行比较，并控制第一晶体管的控制端子的电压。 恒压电源电路包括限流特性控制电路，其根据分压和输出电流来控制第一晶体管的控制端的电压。

公开(公告)号：US06790609B1

公开(公告)日：2004-09-14

申请号：US09786883

申请日：2001-06-07

申请人： Ryoichi Nemori ,  Junji Nishigaki ,  Yutaka Tamura

发明人： Ryoichi Nemori ,  Junji Nishigaki ,  Yutaka Tamura

IPC分类号： C12Q100

CPC分类号： G01N33/68 ,  G01N31/22 ,  G01N33/6815

摘要： A method for measuring a thiol group-containing compound, which comprises the steps of (1) contacting a sample containing a thiol group-containing compound with a thin membrane comprising a microparticle of a substance selected from the group consisting of a metal and a metal compound and comprising a hydrophilic binder; and (2) detecting a color change on the thin membrane resulting from interaction of the thiol group-containing compound and the microparticle, and a thin membrane used for said method. A thiol group containing compound such as an alkylmercaptan or a protein containing thiol groups can be conveniently and accurately measured.

摘要翻译： 一种含硫醇基化合物的测定方法，其特征在于，包括以下步骤：（1）使含有硫醇基的化合物的试样与包含选自金属和金属的物质的微粒的薄膜接触 化合物并包含亲水性粘合剂; 和（2）检测由含硫醇基的化合物和微粒的相互作用产生的薄膜上的颜色变化，以及用于所述方法的薄膜。 含硫醇基的化合物如烷基硫醇或含巯基的蛋白质可以方便，准确地测量。

公开(公告)号：US06759104B2

公开(公告)日：2004-07-06

申请号：US10259778

申请日：2002-09-30

申请人： Seiichiro Hayakawa ,  Akihiko Sakai ,  Akira Esaki ,  Yutaka Tamura

发明人： Seiichiro Hayakawa ,  Akihiko Sakai ,  Akira Esaki ,  Yutaka Tamura

IPC分类号： C09K1900

CPC分类号： G03F7/0275 ,  C08F22/105 ,  C08F222/1006 ,  G03F7/0007 ,  G03F7/027 ,  Y10T428/10 ,  Y10T428/1086

摘要： A photocurable composition, wherein a small amount of an alicyclic skeleton-containing mono(meth) acrylate is incorporated in a combination of an alicyclic skeleton-containing bis(meth)acrylate and a mercapto compound, a cured product obtained by the copolymerization thereof, and a process for producing the cured product.

摘要翻译： 含有脂环式骨架的双（甲基）丙烯酸酯和巯基化合物的组合中含有少量含脂环骨架的单（甲基）丙烯酸酯的光固化性组合物，其通过其共聚得到的固化物和 一种生产固化产物的方法。

公开(公告)号：US5800970A

公开(公告)日：1998-09-01

申请号：US843337

申请日：1997-04-15

申请人： Yutaka Tamura

发明人： Yutaka Tamura

IPC分类号： G03C11/04 ,  G03C1/795 ,  G03C11/06

CPC分类号： G03C11/06 ,  G03C1/7954

摘要： There is disclosed a flaw-mending agent for photographs which comprises a liquid having a refractive index in the range of 1.5 to 1.8, and a viscosity in the range of 0.1 cP to 100 cP. There is also disclosed a method for mending flaws using the flaw-mending agent. The flaw-mending agent is useful for mending flaws on silver halide photographic light-sensitive materials, easy to handle, and high in flaw-mending effect.

摘要翻译： 公开了一种用于照片的修补剂，其包含折射率在1.5至1.8范围内的粘度和0.1cP至100cP范围内的粘度。 还公开了使用瑕疵修补剂修补缺陷的方法。 修补剂可用于修补卤化银照相感光材料上的缺陷，易于处理和高瑕疵修补效果。