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公开(公告)号：US08067237B2
公开(公告)日：2011-11-29
申请号：US11638796
申请日：2006-12-13
申请人： David J. Mooney , Omar Abdel-Rahman Ali , Eduardo Alexandre Barros e Silva , Hyun Joon Kong , Elliott Earl Hill, Jr. , Tanyarut Boontheekul
发明人： David J. Mooney , Omar Abdel-Rahman Ali , Eduardo Alexandre Barros e Silva , Hyun Joon Kong , Elliott Earl Hill, Jr. , Tanyarut Boontheekul
CPC分类号： A61K39/0011 , A61K9/0024 , A61K9/1647 , A61K38/1866 , A61K38/193 , A61K38/39 , A61K39/21 , A61K39/39 , A61K2039/54 , A61K2039/55516 , A61K2039/55522 , A61K2039/55561 , A61K2039/55583 , A61K2039/6093 , A61L27/18 , A61L27/20 , A61L27/3633 , A61L27/38 , A61L27/3826 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2300/232 , A61L2300/252 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/438 , A61L2300/604 , A61L2300/606 , A61L2400/18 , A61L2430/30 , A61L2430/34 , B33Y80/00 , C12N7/00 , C12N15/117 , C12N2310/17 , C12N2320/32 , C12N2740/16034 , Y02A50/411
摘要： A device that includes a scaffold composition and a bioactive composition with the bioactive composition being incorporated into or coated onto the scaffold composition such that the scaffold composition and/or a bioactive composition controls egress of a resident cell or progeny thereof. The devices mediate active recruitment, modification, and release of host cells from the material.
摘要翻译： 一种包括支架组合物和具有生物活性组合物的生物活性组合物的装置，所述生物活性组合物掺入或涂覆在支架组合物上，使得支架组合物和/或生物活性组合物控制驻留细胞或其后代的出口。 该装置介导宿主细胞从材料中的主动募集，修饰和释放。
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公开(公告)号：US20120134967A1
公开(公告)日：2012-05-31
申请号：US13305088
申请日：2011-11-28
申请人： DAVID J. MOONEY , OMAR ABDEL-RAHMAN ALI , EDUARDO ALEXANDRE BARROS E SILVA , HYUN JOON KONG , ELLIOT EARL HILL, JR. , TANYARUT BOONTHEEKUL
发明人： DAVID J. MOONEY , OMAR ABDEL-RAHMAN ALI , EDUARDO ALEXANDRE BARROS E SILVA , HYUN JOON KONG , ELLIOT EARL HILL, JR. , TANYARUT BOONTHEEKUL
CPC分类号： A61K39/0011 , A61K9/0024 , A61K9/1647 , A61K38/1866 , A61K38/193 , A61K38/39 , A61K39/21 , A61K39/39 , A61K2039/54 , A61K2039/55516 , A61K2039/55522 , A61K2039/55561 , A61K2039/55583 , A61K2039/6093 , A61L27/18 , A61L27/20 , A61L27/3633 , A61L27/38 , A61L27/3826 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2300/232 , A61L2300/252 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/438 , A61L2300/604 , A61L2300/606 , A61L2400/18 , A61L2430/30 , A61L2430/34 , B33Y80/00 , C12N7/00 , C12N15/117 , C12N2310/17 , C12N2320/32 , C12N2740/16034 , Y02A50/411
摘要： A device that includes a scaffold composition and a bioactive composition with the bioactive composition being incorporated into or coated onto the scaffold composition such that the scaffold composition and/or a bioactive composition controls egress of a resident cell or progeny thereof. The devices mediate active recruitment, modification, and release of host cells from the material.
摘要翻译： 一种包括支架组合物和具有生物活性组合物的生物活性组合物的装置，所述生物活性组合物掺入或涂覆在支架组合物上，使得支架组合物和/或生物活性组合物控制驻留细胞或其后代的出口。 该装置介导宿主细胞从材料中的主动募集，修饰和释放。
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公开(公告)号：US20110020216A1
公开(公告)日：2011-01-27
申请号：US12665761
申请日：2008-06-11
IPC分类号： A61K51/12 , C12N1/00 , A61K9/00 , B05D1/36 , C12Q1/02 , C12Q1/70 , A61K31/785 , A61K38/00 , A61K38/19 , A61K38/17 , A61K38/16 , A61K38/36 , A61K38/39 , A61K35/12 , A61K35/76 , A61K31/715 , A61K39/395 , A61K38/12 , A61P31/12 , A61P31/04 , A61P31/10 , A61P33/02 , A61P33/10 , A61F2/82
CPC分类号： A61L27/56 , A61L27/50 , A61L27/54 , A61L2300/252 , A61L2300/404 , A61L2300/44 , A61L2300/45 , A61L2300/64
摘要： A device that includes a scaffold composition and a bioactive composition with the bioactive composition being incorporated therein or thereon, or diffusing from the scaffold composition such that the scaffold composition and/or a bioactive composition captures and eliminates undesirable cells from the body a mammalian subject. The devices mediate active recruitment, sequestration, and removal or elimination of undesirable cells from their host.
摘要翻译： 一种包括支架组合物和生物活性组合物的装置，其中所述生物活性组合物掺入其中或其上，或从所述支架组合物扩散，使得所述支架组合物和/或生物活性组合物从哺乳动物受试者身体捕获并消除不期望的细胞。 该装置介入主动招募，隔离和去除或消除不期望的细胞。
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公开(公告)号：US09770535B2
公开(公告)日：2017-09-26
申请号：US12665761
申请日：2008-06-11
CPC分类号： A61L27/56 , A61L27/50 , A61L27/54 , A61L2300/252 , A61L2300/404 , A61L2300/44 , A61L2300/45 , A61L2300/64
摘要： A device that includes a scaffold composition and a bioactive composition with the bioactive composition being incorporated therein or thereon, or diffusing from the scaffold composition such that the scaffold composition and/or a bioactive composition captures and eliminates undesirable cells from the body a mammalian subject. The devices mediate active recruitment, sequestration, and removal or elimination of undesirable cells from their host.
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