公开(公告)号：US08746168B2

公开(公告)日：2014-06-10

申请号：US12892783

申请日：2010-09-28

Applicant: Hamed Abbasian ,  Pamela Chan ,  Valerio Ditizio ,  Vyacheslav Dudnyk ,  Zhaopeng Li ,  Said Loloie ,  Natali Yakeemovich ,  Frank DiCosmo

Inventor： Hamed Abbasian ,  Pamela Chan ,  Valerio Ditizio ,  Vyacheslav Dudnyk ,  Zhaopeng Li ,  Said Loloie ,  Natali Yakeemovich ,  Frank DiCosmo

IPC: B05C3/02 ,  C09D4/00 ,  A61L27/34 ,  A61L29/08 ,  C09D133/08 ,  C08F2/48 ,  A61L31/10 ,  C08J7/18 ,  C08L33/08

CPC classification number: C08F2/48 ,  A61L27/34 ,  A61L29/085 ,  A61L31/10 ,  A61L2400/10 ,  A61L2420/02 ,  C08J7/18 ,  C08L33/08 ,  C09D4/00 ,  C09D133/08

Abstract: A system and method for photo-grafting a coating polymer onto the surface of a medical device are provided. The system comprises a plurality of stations including a novel grafting station. The system and method of the invention are both time- and resource-efficient. The system includes several stations, each station including a dipping tank. The system allows for the automated, semi-automated, or manual dipping of medical devices into the dipping tanks in a specified order, as desired, wherein at least one of the stations is a grafting station for photo-grafting the coating polymer onto the surface of the medical device. The system is modular, which allows for modification of the process as required, depending on the needs of the user. The system may comprise stations for incorporating an antimicrobial agent into the coating, and/or for rendering the coating lubricious.

Abstract translation: 提供了一种用于将涂层聚合物光刻接到医疗器械表面上的系统和方法。 该系统包括多个站，包括一个新颖的移植站。 本发明的系统和方法既时间又资源有效。 该系统包括几个站，每个站包括一个浸渍槽。 该系统允许根据需要以特定的顺序将医疗装置自动化，半自动化或手动地浸入浸渍罐中，其中至少一个站是用于将涂层聚合物光刻接合到表面上的接枝站 的医疗器械。 该系统是模块化的，这允许根据需要修改过程，具体取决于用户的需求。 该系统可以包括用于将抗微生物剂并入涂层中的站和/或用于使涂层润滑的站。

公开(公告)号：US08920886B2

公开(公告)日：2014-12-30

申请号：US12892770

申请日：2010-09-28

Applicant: Hamed Abbasian ,  Pamela Chan ,  Valerio Ditizio ,  Vyacheslav Dudnyk ,  Zhaopeng Li ,  Said Loloie ,  Natali Yakeemovich ,  Frank DiCosmo

Inventor： Hamed Abbasian ,  Pamela Chan ,  Valerio Ditizio ,  Vyacheslav Dudnyk ,  Zhaopeng Li ,  Said Loloie ,  Natali Yakeemovich ,  Frank DiCosmo

IPC: C08J7/18 ,  A61L31/10 ,  C08F2/48 ,  C09D133/08 ,  A61L29/08 ,  C09D4/00 ,  A61L27/34 ,  C08L33/08

CPC classification number: C08F2/48 ,  A61L27/34 ,  A61L29/085 ,  A61L31/10 ,  A61L2400/10 ,  A61L2420/02 ,  C08J7/18 ,  C08L33/08 ,  C09D4/00 ,  C09D133/08

Abstract: One aspect of the present disclosure can include a method for grafting a coating polymer onto a surface of a device. The method can include the following steps: a) submerging the device into a photoinitiator solution; b) without first drying the device, submerging the device into a polymerizable solution; c) bubbling an oxygen-scavenging gas through the polymerizable solution; d) applying a UV light to the device to activate the photoinitiator, thereby grafting the coating polymer onto the device; and e) drying the device.

Abstract translation: 本公开的一个方面可以包括将涂覆聚合物接枝到设备的表面上的方法。 该方法可以包括以下步骤：a）将装置浸入光引发剂溶液中; b）没有首先干燥装置，将装置浸入可聚合溶液中; c）将氧气清除气体鼓泡通过可聚合溶液; d）向该装置施加UV光以激活光引发剂，从而将涂覆聚合物接枝到该装置上; 和e）干燥该装置。

公开(公告)号：US20110100294A1

公开(公告)日：2011-05-05

申请号：US12892799

申请日：2010-09-28

Applicant: Hamed Abbasian ,  Pamela Chan ,  Valerio DiTizio ,  Vyacheslav Dudnyk ,  Zhaopeng Li ,  Said Loloie ,  Natali Yakeemovich ,  Frank DiCosmo

Inventor： Hamed Abbasian ,  Pamela Chan ,  Valerio DiTizio ,  Vyacheslav Dudnyk ,  Zhaopeng Li ,  Said Loloie ,  Natali Yakeemovich ,  Frank DiCosmo

IPC: B05C11/00 ,  B05C11/11

CPC classification number: C08F2/48 ,  A61L27/34 ,  A61L29/085 ,  A61L31/10 ,  A61L2400/10 ,  A61L2420/02 ,  C08J7/18 ,  C08L33/08 ,  C09D4/00 ,  C09D133/08

Abstract: A system and method for photo-grafting a coating polymer onto the surface of a medical device are provided. The system comprises a plurality of stations including a novel grafting station. The system and method of the invention are both time- and resource-efficient. The system includes several stations, each station including a dipping tank. The system allows for the automated, semi-automated, or manual dipping of medical devices into the dipping tanks in a specified order, as desired, wherein at least one of the stations is a grafting station for photo-grafting the coating polymer onto the surface of the medical device. The system is modular, which allows for modification of the process as required, depending on the needs of the user. The system may comprise stations for incorporating an antimicrobial agent into the coating, and/or for rendering the coating lubricious.

Abstract translation: 提供了一种用于将涂层聚合物光刻接到医疗器械表面上的系统和方法。 该系统包括多个站，包括一个新颖的移植站。 本发明的系统和方法既时间又资源有效。 该系统包括几个站，每个站包括一个浸渍槽。 该系统允许根据需要以特定的顺序将医疗装置自动化，半自动化或手动地浸入浸渍罐中，其中至少一个站是用于将涂层聚合物光刻接合到表面上的接枝站 的医疗器械。 该系统是模块化的，这允许根据需要修改过程，具体取决于用户的需求。 该系统可以包括用于将抗微生物剂并入涂层中的站和/或用于使涂层润滑的站。

公开(公告)号：US08967077B2

公开(公告)日：2015-03-03

申请号：US12892799

申请日：2010-09-28

Applicant: Hamed Abbasian ,  Pamela Chan ,  Valerio DiTizio ,  Vyacheslav Dudnyk ,  Zhaopeng Li ,  Said Loloie ,  Natali Yakeemovich ,  Frank DiCosmo

Inventor： Hamed Abbasian ,  Pamela Chan ,  Valerio DiTizio ,  Vyacheslav Dudnyk ,  Zhaopeng Li ,  Said Loloie ,  Natali Yakeemovich ,  Frank DiCosmo

IPC: B05C3/02 ,  C09D4/00 ,  A61L27/34 ,  A61L29/08 ,  A61L31/10 ,  C08F2/48 ,  C08J7/18 ,  C09D133/08 ,  C08L33/08

CPC classification number: C08F2/48 ,  A61L27/34 ,  A61L29/085 ,  A61L31/10 ,  A61L2400/10 ,  A61L2420/02 ,  C08J7/18 ,  C08L33/08 ,  C09D4/00 ,  C09D133/08

Abstract: A system and method for photo-grafting a coating polymer onto the surface of a medical device are provided. The system comprises a plurality of stations including a novel grafting station. The system and method of the invention are both time- and resource-efficient. The system includes several stations, each station including a dipping tank. The system allows for the automated, semi-automated, or manual dipping of medical devices into the dipping tanks in a specified order, as desired, wherein at least one of the stations is a grafting station for photo-grafting the coating polymer onto the surface of the medical device. The system is modular, which allows for modification of the process as required, depending on the needs of the user. The system may comprise stations for incorporating an antimicrobial agent into the coating, and/or for rendering the coating lubricious.

Abstract translation: 提供了一种用于将涂层聚合物光刻接到医疗器械表面上的系统和方法。 该系统包括多个站，包括一个新颖的移植站。 本发明的系统和方法既时间又资源有效。 该系统包括几个站，每个站包括一个浸渍槽。 该系统允许根据需要以特定的顺序将医疗装置自动化，半自动化或手动地浸入浸渍罐中，其中至少一个站是用于将涂层聚合物光刻接合到表面上的接枝站 的医疗器械。 该系统是模块化的，这允许根据需要修改过程，具体取决于用户的需求。 该系统可以包括用于将抗微生物剂并入涂层中的站和/或用于使涂层润滑的站。

公开(公告)号：US20110100293A1

公开(公告)日：2011-05-05

申请号：US12892783

申请日：2010-09-28

Applicant: Hamed Abbasian ,  Pamela Chan ,  Valerio DiTizio ,  Vyacheslav Dudnyk ,  Zhaopeng Li ,  Said Loloie ,  Natali Yakeemovich ,  Frank DiCosmo

Inventor： Hamed Abbasian ,  Pamela Chan ,  Valerio DiTizio ,  Vyacheslav Dudnyk ,  Zhaopeng Li ,  Said Loloie ,  Natali Yakeemovich ,  Frank DiCosmo

IPC: B05C9/08 ,  B05C11/00

CPC classification number: C08F2/48 ,  A61L27/34 ,  A61L29/085 ,  A61L31/10 ,  A61L2400/10 ,  A61L2420/02 ,  C08J7/18 ,  C08L33/08 ,  C09D4/00 ,  C09D133/08

Abstract: A system and method for photo-grafting a coating polymer onto the surface of a medical device are provided. The system comprises a plurality of stations including a novel grafting station. The system and method of the invention are both time- and resource-efficient. The system includes several stations, each station including a dipping tank. The system allows for the automated, semi-automated, or manual dipping of medical devices into the dipping tanks in a specified order, as desired, wherein at least one of the stations is a grafting station for photo-grafting the coating polymer onto the surface of the medical device. The system is modular, which allows for modification of the process as required, depending on the needs of the user. The system may comprise stations for incorporating an antimicrobial agent into the coating, and/or for rendering the coating lubricious.

公开(公告)号：US20110104390A1

公开(公告)日：2011-05-05

申请号：US12892770

申请日：2010-09-28

Applicant: Hamed Abbasian ,  Pamela Chan ,  Valerio Ditizio ,  Vyacheslav Dudnyk ,  Zhaopeng Li ,  Said Loloie ,  Natali Yakeemovich ,  Frank Dicosmo

Inventor： Hamed Abbasian ,  Pamela Chan ,  Valerio Ditizio ,  Vyacheslav Dudnyk ,  Zhaopeng Li ,  Said Loloie ,  Natali Yakeemovich ,  Frank Dicosmo

IPC: C08J7/18

CPC classification number: C08F2/48 ,  A61L27/34 ,  A61L29/085 ,  A61L31/10 ,  A61L2400/10 ,  A61L2420/02 ,  C08J7/18 ,  C08L33/08 ,  C09D4/00 ,  C09D133/08

Abstract: A system and method for photo-grafting a coating polymer onto the surface of a medical device are provided. The system comprises a plurality of stations including a novel grafting station. The system and method of the invention are both time- and resource-efficient. The system includes several stations, each station including a dipping tank. The system allows for the automated, semi-automated, or manual dipping of medical devices into the dipping tanks in a specified order, as desired, wherein at least one of the stations is a grafting station for photo-grafting the coating polymer onto the surface of the medical device. The system is modular, which allows for modification of the process as required, depending on the needs of the user. The system may comprise stations for incorporating an antimicrobial agent into the coating, and/or for rendering the coating lubricious.