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公开(公告)号：US20110100293A1
公开(公告)日：2011-05-05
申请号：US12892783
申请日：2010-09-28
Applicant: Hamed Abbasian , Pamela Chan , Valerio DiTizio , Vyacheslav Dudnyk , Zhaopeng Li , Said Loloie , Natali Yakeemovich , Frank DiCosmo
Inventor： Hamed Abbasian , Pamela Chan , Valerio DiTizio , Vyacheslav Dudnyk , Zhaopeng Li , Said Loloie , Natali Yakeemovich , Frank DiCosmo
CPC classification number: C08F2/48 , A61L27/34 , A61L29/085 , A61L31/10 , A61L2400/10 , A61L2420/02 , C08J7/18 , C08L33/08 , C09D4/00 , C09D133/08
Abstract: A system and method for photo-grafting a coating polymer onto the surface of a medical device are provided. The system comprises a plurality of stations including a novel grafting station. The system and method of the invention are both time- and resource-efficient. The system includes several stations, each station including a dipping tank. The system allows for the automated, semi-automated, or manual dipping of medical devices into the dipping tanks in a specified order, as desired, wherein at least one of the stations is a grafting station for photo-grafting the coating polymer onto the surface of the medical device. The system is modular, which allows for modification of the process as required, depending on the needs of the user. The system may comprise stations for incorporating an antimicrobial agent into the coating, and/or for rendering the coating lubricious.
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公开(公告)号：US08967077B2
公开(公告)日：2015-03-03
申请号：US12892799
申请日：2010-09-28
Applicant: Hamed Abbasian , Pamela Chan , Valerio DiTizio , Vyacheslav Dudnyk , Zhaopeng Li , Said Loloie , Natali Yakeemovich , Frank DiCosmo
Inventor： Hamed Abbasian , Pamela Chan , Valerio DiTizio , Vyacheslav Dudnyk , Zhaopeng Li , Said Loloie , Natali Yakeemovich , Frank DiCosmo
IPC: B05C3/02 , C09D4/00 , A61L27/34 , A61L29/08 , A61L31/10 , C08F2/48 , C08J7/18 , C09D133/08 , C08L33/08
CPC classification number: C08F2/48 , A61L27/34 , A61L29/085 , A61L31/10 , A61L2400/10 , A61L2420/02 , C08J7/18 , C08L33/08 , C09D4/00 , C09D133/08
Abstract: A system and method for photo-grafting a coating polymer onto the surface of a medical device are provided. The system comprises a plurality of stations including a novel grafting station. The system and method of the invention are both time- and resource-efficient. The system includes several stations, each station including a dipping tank. The system allows for the automated, semi-automated, or manual dipping of medical devices into the dipping tanks in a specified order, as desired, wherein at least one of the stations is a grafting station for photo-grafting the coating polymer onto the surface of the medical device. The system is modular, which allows for modification of the process as required, depending on the needs of the user. The system may comprise stations for incorporating an antimicrobial agent into the coating, and/or for rendering the coating lubricious.
Abstract translation: 提供了一种用于将涂层聚合物光刻接到医疗器械表面上的系统和方法。 该系统包括多个站，包括一个新颖的移植站。 本发明的系统和方法既时间又资源有效。 该系统包括几个站，每个站包括一个浸渍槽。 该系统允许根据需要以特定的顺序将医疗装置自动化，半自动化或手动地浸入浸渍罐中，其中至少一个站是用于将涂层聚合物光刻接合到表面上的接枝站 的医疗器械。 该系统是模块化的，这允许根据需要修改过程，具体取决于用户的需求。 该系统可以包括用于将抗微生物剂并入涂层中的站和/或用于使涂层润滑的站。
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公开(公告)号：US20110104390A1
公开(公告)日：2011-05-05
申请号：US12892770
申请日：2010-09-28
Applicant: Hamed Abbasian , Pamela Chan , Valerio Ditizio , Vyacheslav Dudnyk , Zhaopeng Li , Said Loloie , Natali Yakeemovich , Frank Dicosmo
Inventor： Hamed Abbasian , Pamela Chan , Valerio Ditizio , Vyacheslav Dudnyk , Zhaopeng Li , Said Loloie , Natali Yakeemovich , Frank Dicosmo
IPC: C08J7/18
CPC classification number: C08F2/48 , A61L27/34 , A61L29/085 , A61L31/10 , A61L2400/10 , A61L2420/02 , C08J7/18 , C08L33/08 , C09D4/00 , C09D133/08
Abstract: A system and method for photo-grafting a coating polymer onto the surface of a medical device are provided. The system comprises a plurality of stations including a novel grafting station. The system and method of the invention are both time- and resource-efficient. The system includes several stations, each station including a dipping tank. The system allows for the automated, semi-automated, or manual dipping of medical devices into the dipping tanks in a specified order, as desired, wherein at least one of the stations is a grafting station for photo-grafting the coating polymer onto the surface of the medical device. The system is modular, which allows for modification of the process as required, depending on the needs of the user. The system may comprise stations for incorporating an antimicrobial agent into the coating, and/or for rendering the coating lubricious.
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Patent Agency Ranking
公开(公告)号：US08746168B2
公开(公告)日：2014-06-10
申请号：US12892783
申请日：2010-09-28
Applicant: Hamed Abbasian , Pamela Chan , Valerio Ditizio , Vyacheslav Dudnyk , Zhaopeng Li , Said Loloie , Natali Yakeemovich , Frank DiCosmo
Inventor： Hamed Abbasian , Pamela Chan , Valerio Ditizio , Vyacheslav Dudnyk , Zhaopeng Li , Said Loloie , Natali Yakeemovich , Frank DiCosmo
IPC: B05C3/02 , C09D4/00 , A61L27/34 , A61L29/08 , C09D133/08 , C08F2/48 , A61L31/10 , C08J7/18 , C08L33/08
CPC classification number: C08F2/48 , A61L27/34 , A61L29/085 , A61L31/10 , A61L2400/10 , A61L2420/02 , C08J7/18 , C08L33/08 , C09D4/00 , C09D133/08
Abstract: A system and method for photo-grafting a coating polymer onto the surface of a medical device are provided. The system comprises a plurality of stations including a novel grafting station. The system and method of the invention are both time- and resource-efficient. The system includes several stations, each station including a dipping tank. The system allows for the automated, semi-automated, or manual dipping of medical devices into the dipping tanks in a specified order, as desired, wherein at least one of the stations is a grafting station for photo-grafting the coating polymer onto the surface of the medical device. The system is modular, which allows for modification of the process as required, depending on the needs of the user. The system may comprise stations for incorporating an antimicrobial agent into the coating, and/or for rendering the coating lubricious.
Abstract translation: 提供了一种用于将涂层聚合物光刻接到医疗器械表面上的系统和方法。 该系统包括多个站，包括一个新颖的移植站。 本发明的系统和方法既时间又资源有效。 该系统包括几个站，每个站包括一个浸渍槽。 该系统允许根据需要以特定的顺序将医疗装置自动化，半自动化或手动地浸入浸渍罐中，其中至少一个站是用于将涂层聚合物光刻接合到表面上的接枝站 的医疗器械。 该系统是模块化的，这允许根据需要修改过程，具体取决于用户的需求。 该系统可以包括用于将抗微生物剂并入涂层中的站和/或用于使涂层润滑的站。
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5.发明授权Method for treating a surface with a coating comprising a microencapsulated therapeutic agent and device with treated surface 有权用包含治疗剂的涂层和具有处理过的表面的装置处理表面的方法公开(公告)号：US08697112B2
公开(公告)日：2014-04-15
申请号：US13543337
申请日：2012-07-06
Applicant: Vyacheslav Dudnyk , Valerio DiTizio
Inventor： Vyacheslav Dudnyk , Valerio DiTizio
CPC classification number: A61L27/34 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/104 , A61L2300/206 , A61L2300/404 , A61L2300/418 , A61L2300/606 , A61L2300/622 , A61L2420/02 , A61L2420/04 , A61L2420/08 , C08L33/00
Abstract: A method for treating a surface with a therapeutic agent is disclosed. The method comprises precipitating a therapeutic agent from a hydrophilic polymeric base layer with which the therapeutic agent has been complexed, to form a layer comprising microparticles of the therapeutic agent on the hydrophilic polymeric base layer, the hydrophilic polymeric base layer being grafted to the surface. Devices comprising a surface having a hydrophilic polymeric base layer comprising a hydrophilic polymer grafted to the surface and a layer comprising microparticles of a therapeutic agent disposed on and complexed with the hydrophilic polymeric base layer are also disclosed.
Abstract translation: 公开了一种用治疗剂处理表面的方法。 所述方法包括从治疗剂已经被复合的亲水聚合物基底层沉淀治疗剂，以在亲水性聚合物基底层上形成包含治疗剂微粒的层，亲水性聚合物基层被接枝到表面。 还公开了包含具有亲水聚合物基层的表面的装置，其包含接枝到表面的亲水性聚合物和包含设置在亲水性聚合物基底层上并与亲水性聚合物基底层复合的治疗剂的微粒的层。
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公开(公告)号：US08920886B2
公开(公告)日：2014-12-30
申请号：US12892770
申请日：2010-09-28
Applicant: Hamed Abbasian , Pamela Chan , Valerio Ditizio , Vyacheslav Dudnyk , Zhaopeng Li , Said Loloie , Natali Yakeemovich , Frank DiCosmo
Inventor： Hamed Abbasian , Pamela Chan , Valerio Ditizio , Vyacheslav Dudnyk , Zhaopeng Li , Said Loloie , Natali Yakeemovich , Frank DiCosmo
CPC classification number: C08F2/48 , A61L27/34 , A61L29/085 , A61L31/10 , A61L2400/10 , A61L2420/02 , C08J7/18 , C08L33/08 , C09D4/00 , C09D133/08
Abstract: One aspect of the present disclosure can include a method for grafting a coating polymer onto a surface of a device. The method can include the following steps: a) submerging the device into a photoinitiator solution; b) without first drying the device, submerging the device into a polymerizable solution; c) bubbling an oxygen-scavenging gas through the polymerizable solution; d) applying a UV light to the device to activate the photoinitiator, thereby grafting the coating polymer onto the device; and e) drying the device.
Abstract translation: 本公开的一个方面可以包括将涂覆聚合物接枝到设备的表面上的方法。 该方法可以包括以下步骤：a）将装置浸入光引发剂溶液中; b）没有首先干燥装置，将装置浸入可聚合溶液中; c）将氧气清除气体鼓泡通过可聚合溶液; d）向该装置施加UV光以激活光引发剂，从而将涂覆聚合物接枝到该装置上; 和e）干燥该装置。
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7.发明申请METHOD FOR TREATING A SURFACE WITH A COATING COMPRISING A THERAPEUTIC AGENT AND DEVICE WITH TREATED SURFACE 有权用包含治疗剂和包含处理表面的装置的涂层处理表面的方法公开(公告)号：US20130039953A1
公开(公告)日：2013-02-14
申请号：US13543337
申请日：2012-07-06
Applicant: Vyacheslav Dudnyk , Valerio DiTizio
Inventor： Vyacheslav Dudnyk , Valerio DiTizio
IPC: A61K9/14 , A61P31/00 , A61K38/02 , A61K31/7088 , A61K33/38 , A61K38/14 , A61K31/65 , A61K33/18 , A61K33/12 , A61K33/42 , A61K33/28 , A61K33/34 , A61K33/26 , A61K33/24 , A61K33/30 , A61K33/06 , A61K31/28 , A61K31/155 , A61P35/00 , A61P11/00 , A61L33/00 , A61K9/00
CPC classification number: A61L27/34 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/104 , A61L2300/206 , A61L2300/404 , A61L2300/418 , A61L2300/606 , A61L2300/622 , A61L2420/02 , A61L2420/04 , A61L2420/08 , C08L33/00
Abstract: A method for treating a surface with a therapeutic agent is disclosed. The method comprises precipitating a therapeutic agent from a hydrophilic polymeric base layer with which the therapeutic agent has been complexed, to form a layer comprising microparticles of the therapeutic agent on the hydrophilic polymeric base layer, the hydrophilic polymeric base layer being grafted to the surface. Devices comprising a surface having a hydrophilic polymeric base layer comprising a hydrophilic polymer grafted to the surface and a layer comprising microparticles of a therapeutic agent disposed on and complexed with the hydrophilic polymeric base layer are also disclosed.
Abstract translation: 公开了一种用治疗剂处理表面的方法。 所述方法包括从治疗剂已经被复合的亲水聚合物基底层沉淀治疗剂，以在亲水性聚合物基底层上形成包含治疗剂微粒的层，亲水性聚合物基层被接枝到表面。 还公开了包含具有亲水聚合物基层的表面的装置，其包含接枝到表面的亲水性聚合物和包含设置在亲水性聚合物基底层上并与亲水性聚合物基底层复合的治疗剂的微粒的层。
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公开(公告)号：US20110100294A1
公开(公告)日：2011-05-05
申请号：US12892799
申请日：2010-09-28
Applicant: Hamed Abbasian , Pamela Chan , Valerio DiTizio , Vyacheslav Dudnyk , Zhaopeng Li , Said Loloie , Natali Yakeemovich , Frank DiCosmo
Inventor： Hamed Abbasian , Pamela Chan , Valerio DiTizio , Vyacheslav Dudnyk , Zhaopeng Li , Said Loloie , Natali Yakeemovich , Frank DiCosmo
CPC classification number: C08F2/48 , A61L27/34 , A61L29/085 , A61L31/10 , A61L2400/10 , A61L2420/02 , C08J7/18 , C08L33/08 , C09D4/00 , C09D133/08
Abstract: A system and method for photo-grafting a coating polymer onto the surface of a medical device are provided. The system comprises a plurality of stations including a novel grafting station. The system and method of the invention are both time- and resource-efficient. The system includes several stations, each station including a dipping tank. The system allows for the automated, semi-automated, or manual dipping of medical devices into the dipping tanks in a specified order, as desired, wherein at least one of the stations is a grafting station for photo-grafting the coating polymer onto the surface of the medical device. The system is modular, which allows for modification of the process as required, depending on the needs of the user. The system may comprise stations for incorporating an antimicrobial agent into the coating, and/or for rendering the coating lubricious.
Abstract translation: 提供了一种用于将涂层聚合物光刻接到医疗器械表面上的系统和方法。 该系统包括多个站，包括一个新颖的移植站。 本发明的系统和方法既时间又资源有效。 该系统包括几个站，每个站包括一个浸渍槽。 该系统允许根据需要以特定的顺序将医疗装置自动化，半自动化或手动地浸入浸渍罐中，其中至少一个站是用于将涂层聚合物光刻接合到表面上的接枝站 的医疗器械。 该系统是模块化的，这允许根据需要修改过程，具体取决于用户的需求。 该系统可以包括用于将抗微生物剂并入涂层中的站和/或用于使涂层润滑的站。
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