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    Optically variable device with diffraction-based micro-optics, method of creating the same, and article employing the same
    1.
    发明授权
    Optically variable device with diffraction-based micro-optics, method of creating the same, and article employing the same 有权
    具有衍射的微光学的光学可变器件，其制造方法和使用其的制品

    公开(公告)号：US08488242B2

    公开(公告)日：2013-07-16

    申请号：US11425224

    申请日：2006-06-20

    申请人： Dean R. Hill ,  Robert E. Renton ,  Andrew K. Rowe ,  Paul Dunn

    发明人： Dean R. Hill ,  Robert E. Renton ,  Andrew K. Rowe ,  Paul Dunn

    IPC分类号： G02B27/44

    CPC分类号： B42D25/328 ,  B42D25/29 ,  B42D25/342 ,  B42D25/45 ,  B42D2035/24 ,  B42D2035/44 ,  G02B5/1842 ,  G02B5/1885

    摘要： A security device includes an optically variable device (OVD) having diffraction-based micro-optics including at least one moiré magnified visual representation of a micro-object. A diffractive structure provides micro-objects with unique optical effects when the OVD is viewed through the micro-object structure from a predetermined relative observation point. In addition to magnifying the micro-objects, the diffractive structure can impart optical effects such as change in observed color, enhanced contrast, animation of the observed visual representation, and change in size or shape of the observed visual representation. The micro-objects and the diffractive structure can be disposed on the same or different portions of a substrate. A method of making OVDs, and an article employing such OVDs are also disclosed.

    摘要翻译： 安全装置包括具有基于衍射的微观光学的光学可变装置（OVD），其包括微物体的至少一个莫尔放大的视觉表示。 当从预定的相对观察点通过微物体结构观察OVD时，衍射结构为微物体提供独特的光学效果。 除了放大微物体之外，衍射结构可以赋予光学效果，例如观察到的颜色的变化，增强的对比度，观察到的视觉表现的动画，以及观察到的视觉表现的大小或形状的变化。 微物体和衍射结构可以设置在基底的相同或不同部分上。 还公开了制造OVD的方法和使用这种OVD的物品。

    Mutant Viruses
    2.
    发明申请
    Mutant Viruses 有权
    突变病毒

    公开(公告)号：US20090274728A1

    公开(公告)日：2009-11-05

    申请号：US12436382

    申请日：2009-05-06

    申请人： Susanne Moira Brown ,  Bhuvanesh Singh ,  Ian Ganly ,  Paul Dunn

    发明人： Susanne Moira Brown ,  Bhuvanesh Singh ,  Ian Ganly ,  Paul Dunn

    IPC分类号： A61K39/245 ,  C12N7/01 ,  A61K35/76 ,  C12N15/66

    CPC分类号： A61K38/00 ,  C12N15/1135 ,  C12N15/86 ,  C12N2710/16643 ,  C12N2840/203

    摘要： An herpes simplex virus wherein the herpes simplex virus genome comprises nucleic acid encoding an antisense to the squamous cell carcinoma related oncogene (asSCCRO); and an herpes simplex virus wherein the herpes simplex virus genome comprises nucleic acid encoding a short interfering ribonucleic acid (siRNA) molecule that is capable of repressing or silencing expression of squamous cell carcinoma related oncogene (SCCRO) nucleic acid or polypeptide are disclosed together with methods for generation and applications of such viruses.

    摘要翻译： 单纯疱疹病毒，其中单纯疱疹病毒基因组包含编码与鳞状细胞癌相关致癌基因（asSCCRO）反义的核酸; 和单纯疱疹病毒，其中所述单纯疱疹病毒基因组包含编码能够抑制或沉默鳞状细胞癌相关致癌基因（SCCRO）核酸或多肽的表达的短干扰核糖核酸（siRNA）分子的核酸以及方法 用于生成和应用此类病毒。

    Vectors, mutant viruses and methods for generating mutant viruses
    4.
    发明申请
    Vectors, mutant viruses and methods for generating mutant viruses 审中-公开
    载体，突变病毒和产生突变病毒的方法

    公开(公告)号：US20070110720A1

    公开(公告)日：2007-05-17

    申请号：US10579607

    申请日：2004-11-17

    申请人： Susanne Brown ,  Joe Conner ,  Paul Dunn

    发明人： Susanne Brown ,  Joe Conner ,  Paul Dunn

    IPC分类号： A61K48/00 ,  C12N15/86 ,  C12N7/00

    CPC分类号： C12N15/1135 ,  A01K2267/0331 ,  A61K35/13 ,  A61K48/00 ,  A61K2039/5256 ,  C12N7/00 ,  C12N15/86 ,  C12N2710/16643 ,  C12N2840/203

    摘要： A nucleic acid vector comprising first and second nucleotide sequences corresponding to nucleotide sequences flanking an insertion site in the genome of a selected herpes simplex virus strain; and a cassette located between said first and second nucleotide sequences comprising nucleic acid encoding: (a) one or a plurality of insertion sites and/or a nucleotide sequence of interest; and (b) a ribosome binding site or a regulatory nucleotide sequence; and (c) a marker is disclosed. Herpes simplex viruses generated using said vector, methods for their generation and herpes simplex viruses having a genome comprising heterologous nucleic acid are also disclosed.

    摘要翻译： 核酸载体，其包含对应于选定的单纯疱疹病毒株的基因组中插入位点侧翼的核苷酸序列的第一和第二核苷酸序列; 和位于所述第一和第二核苷酸序列之间的盒，其包含编码以下核酸的核酸：（a）一个或多个插入位点和/或感兴趣的核苷酸序列; 和（b）核糖体结合位点或调节核苷酸序列; 和（c）公开了一种标记。 还公开了使用所述载体产生的单纯疱疹病毒，其产生的方法和具有包含异源核酸的基因组的单纯疱疹病毒。

    Electrostatic discharge failure avoidance through interaction between floorplanning and power routing
    5.
    发明申请
    Electrostatic discharge failure avoidance through interaction between floorplanning and power routing 失效
    通过布局规划和电源布线之间的相互作用来避免静电放电故障

    公开(公告)号：US20070035900A1

    公开(公告)日：2007-02-15

    申请号：US11202275

    申请日：2005-08-11

    申请人： Andrew Huber ,  Ciaran Brennan ,  Paul Dunn ,  Scott Gould ,  Lin Lin ,  Erich Schanzenbach

    发明人： Andrew Huber ,  Ciaran Brennan ,  Paul Dunn ,  Scott Gould ,  Lin Lin ,  Erich Schanzenbach

    IPC分类号： H02H9/00

    CPC分类号： G06F17/5068

    摘要： An integrated system and method to achieve ESD robustness on an integrated circuit (IC) in a fully automated ASIC design environment is described. Electrical characteristics and electrical limits on the power network are translated to power route region constraints for each chip input/output (I/O) cell. Electrical limits on the signal network are translated into signal route region constraints for each chip I/O cell. These constraints are passed on to an I/O floorplanner (automatic placer of I/O cells) that analyzes trade-offs between these constraints. For I/O cells that can not be placed to satisfy both power and signal region constraints, the I/O floorplanner utilizes the knowledge of alternative power distribution structures to group I/Os and create local power grid structures that have the effect of relaxing the power region constraints. Instructions for creating these local power grid structures are passed on to the automatic power routing tool.

    摘要翻译： 描述了在完全自动化ASIC设计环境中实现集成电路（IC）上ESD稳定性的集成系统和方法。 电力网络上的电气特性和电气限制被转换为每个芯片输入/输出（I / O）单元的功率路由区域约束。 信号网络上的电气限制被转换为每个芯片I / O单元的信号路由区域约束。 这些约束被传递到分析这些限制之间的权衡的I / O平面布局（I / O单元的自动放置器）。 对于不能放置以满足功率和信号区域约束的I / O单元，I / O平面布置器利用替代功率分配结构的知识来分组I / O，并创建具有放松效果的局部电网结构 功率区域约束。 创建这些局部电网结构的说明将传递给自动电力布线工具。

    Multi-channel wavelength monitor
    6.
    发明授权
    Multi-channel wavelength monitor 有权
    多声道波长监视器

    公开(公告)号：US06486950B1

    公开(公告)日：2002-11-26

    申请号：US09729876

    申请日：2000-12-05

    申请人： Timothy C. Munks ,  Paul Dunn

    发明人： Timothy C. Munks ,  Paul Dunn

    IPC分类号： G01N2125

    CPC分类号： G02B6/4215 ,  G01J3/2803 ,  G02B6/29361 ,  G02B6/29385 ,  H04J14/02

    摘要： A multi-channel wavelength monitor is described that includes a dispersive element that is positioned in an optical path of an incident optical beam having a plurality of wavelengths. The dispersive element disperses the optical beam into a plurality of optical beams that simultaneously propagate in a plurality of optical paths, where each of the plurality of optical beams has one of the plurality of wavelengths. An optical filter is positioned to intercept each of the plurality of optical paths at a plurality of locations. The optical filter substantially passes a respective one of the plurality of optical beams at a respective one of the plurality of locations and substantially blocks the other optical beams. A plurality of optical detectors is positioned adjacent to the optical filter in a direction of propagation of the plurality of optical beams. A respective one of the plurality of optical detectors is positioned in a respective one of the plurality of optical paths. Each of the plurality of detectors generates an electrical signal that is proportional to an intensity of a respective one of the plurality of optical beams.

    摘要翻译： 描述了一种多通道波长监视器，其包括位于具有多个波长的入射光束的光路中的色散元件。 分散元件将光束分散成多个光束，其同时在多个光路中传播，其中多个光束中的每一个具有多个波长中的一个。 光学滤波器被定位成在多个位置处截取多个光路中的每一个。 滤光器基本上在多个位置中的相应一个处通过多个光束中的相应一个，并且基本上阻挡其它光束。 多个光学检测器位于与滤光器相邻的多个光束的传播方向上。 多个光学检测器中的相应一个位于多个光路中的相应一个光路中。 多个检测器中的每个检测器产生与多个光束中的相应光束的强度成比例的电信号。

    Integrated wavelength-select transmitter
    7.
    发明授权
    Integrated wavelength-select transmitter 失效
    集成波长选择发射机

    公开(公告)号：US06370290B1

    公开(公告)日：2002-04-09

    申请号：US08934189

    申请日：1997-09-19

    申请人： Gary A. Ball ,  Robert W. Ade ,  Karl Kissa ,  Paul Dunn ,  Timothy C. Munks ,  Ronald T. Logan, Jr. ,  Eitan Gertel

    发明人： Gary A. Ball ,  Robert W. Ade ,  Karl Kissa ,  Paul Dunn ,  Timothy C. Munks ,  Ronald T. Logan, Jr. ,  Eitan Gertel

    IPC分类号： G02B612

    CPC分类号： G02B6/4201 ,  G02B6/4215 ,  G02B6/4239 ,  G02B6/4244 ,  G02B6/4266 ,  G02B6/4271 ,  G02B6/4285

    摘要： An integrated optical transmitter for use in an optical system has an optical head assembly with an optical beam generator for providing an optical beam and a lens assembly collecting the optical beam and generating therefrom a formed optical beam. Interface optics receives the formed optical beam and provides optical coupling so as to minimize insertion loss to the optical beam. Also included is an optical modulator for receiving the optical beam from the interface optics and for providing a modulated optical beam in response to received modulation signals. The optical modulator is coupled to the interface optics to be in a fixed relationship therewith.

    摘要翻译： 用于光学系统的集成光发射器具有光学头组件，其具有用于提供光束的光束发生器和收集光束并由其产生形成的光束的透镜组件。 接口光学器件接收所形成的光束并提供光耦合，以使对光束的插入损耗最小化。 还包括用于从接口光学器件接收光束并响应于接收到的调制信号提供调制光束的光调制器。 光调制器耦合到界面光学器件以与其成为固定的关系。