公开(公告)号：US20140005499A1

公开(公告)日：2014-01-02

申请号：US14002341

申请日：2012-03-19

申请人： Michael Catt ,  Michael Trenell

发明人： Michael Catt ,  Michael Trenell

IPC分类号： A61B5/145 ,  A61B5/1459 ,  A61B5/01 ,  A61B5/053 ,  A61B5/11 ,  A61B5/00

CPC分类号： A61B5/14532 ,  A61B5/0022 ,  A61B5/01 ,  A61B5/0531 ,  A61B5/1112 ,  A61B5/1118 ,  A61B5/14503 ,  A61B5/1459 ,  A61B5/7246 ,  A61B5/7405 ,  A61B5/742 ,  A61B5/7455 ,  A61B5/746 ,  A61B2562/0219 ,  A61B2562/028 ,  G06F19/00 ,  G06F19/3456 ,  G06F19/3481 ,  G16H50/20

摘要： The present invention relates to a self monitoring device for attachment to the body, which incorporates real-time and correlated measurement of body movement and physiological analytes of metabolism (e.g. glucose) that can be modulated by physical activity. The system enables real time and personalised modulation of the selected physiological analyte(s) through appropriately selected cued activities and other evidence based clinical guidance dependent on previous and current analyte levels correlated with previous and current patterns of movement. The system also allows for personalisation of the outputs with regular calibration to the user.

摘要翻译： 本发明涉及一种用于附着到身体的自我监测装置，其包括身体运动的实时和相关测量以及可以通过身体活动调节的代谢的生理分析物（例如葡萄糖）。 该系统通过适当选择的提示活动和依赖于与先前和当前运动模式相关的先前和当前分析物水平的其他基于证据的临床指导，实现对所选生理分析物的实时和个性化调制。 该系统还允许通过定期校准向用户个性化输出。

公开(公告)号：US07141212B2

公开(公告)日：2006-11-28

申请号：US08338141

申请日：1994-11-09

申请人： Michael Catt ,  Paul Henry Mundill ,  Michael Evans Prior

发明人： Michael Catt ,  Paul Henry Mundill ,  Michael Evans Prior

IPC分类号： G01N21/00

CPC分类号： G01N21/8483 ,  B01L3/5023 ,  B01L2200/12 ,  B01L2300/0825 ,  B01L2400/0406 ,  G01N2021/8618 ,  G01N2021/8654 ,  G01N2201/06153 ,  G01N2201/0696

摘要： A method of “reading” the result of an assay effected by concentrating a detectable material in a comparatively small zone of a carrier in the form of a strip, sheet or layer through the thickness of which electromagnetic radiation such as visible light is transmissible, wherein at least a portion of one face or the carrier is exposed to incident electromagnetic radiation which is substantially uniform across the entire portion, the portion including the small zone, and electromagnetic radiation emerging from the opposite face of the carrier is measured to determine the assay result. Preferably the radiation is diffuse light.

摘要翻译： 通过将可检测材料集中在带状，片状或层状形式的载体的相对小的区域中，通过将电磁辐射如可见光透射的厚度集中在其中，“读取”测定结果的方法，其中 一个面或载体的至少一部分暴露于跨越整个部分基本均匀的入射电磁辐射，测量包括小区域的部分和从载体的相对面出射的电磁辐射以确定测定结果 。 优选地，辐射是漫射光。

公开(公告)号：US06235241B1

公开(公告)日：2001-05-22

申请号：US09078501

申请日：1998-05-14

申请人： Michael Catt ,  Paul Henry Mundill ,  Michael Evans Prior

发明人： Michael Catt ,  Paul Henry Mundill ,  Michael Evans Prior

IPC分类号： G01N2100

CPC分类号： B01L3/5023 ,  B01L2200/12 ,  B01L2300/0825 ,  B01L2400/0406 ,  G01N21/8483 ,  G01N2021/8618 ,  G01N2021/8654 ,  G01N2201/06153 ,  G01N2201/0696

摘要： An assay result reader, for use in conjunction with an assay device comprising a porous liquid-permeable carrier in the form of a strip or sheet through the thickness of which electromagnetic radiation is transmissible, the carrier including a detection zone in which an assay result is revealed by specific binding of a detectable material directly or indirectly to a binding agent immobilized in the detection zone, detection of the detectable material being effected by determining the extent to which electromagnetic radiation transmitted through the thickness of said carrier is attenuated by the presence of the detectable material bound in the detection zone.

摘要翻译： 测定结果读取器，用于与测定装置结合使用，所述测定装置包括通过电磁辐射可传播的厚度的带状或片状形式的多孔液体可渗透载体，所述载体包括检测区域，其中测定结果为 通过将可检测材料直接或间接地特异性结合到固定在检测区中的结合剂来显示，可检测材料的检测是通过确定通过所述载体的厚度传输的电磁辐射的程度通过存在 在检测区域中结合的可检测材料。

公开(公告)号：US06403380B1

公开(公告)日：2002-06-11

申请号：US08801212

申请日：1997-02-18

申请人： Michael Catt ,  Keith May

发明人： Michael Catt ,  Keith May

IPC分类号： A61B1000

CPC分类号： G01N33/743

摘要： A method of providing warning of the onset of the fertile phase of the human ovulation cycle, involving measurement in absolute or relative terms of the body fluid concentration of an analyte such as estradiol or a metabolite thereof wherein if in the current cycle a concentration measurement conducted at about the termination of menses reveals a body fluid concentration that is typical of that found in the body fluid of an average human female subject about 3 days prior to the time of ovulation during a 28-day cycle, the current cycle is immediately declared to be in its fertile phase. Where the a analyte is E3G, the E3G concentration measurement is conducted on at least one or numerical days 4 to 7 of the current cycle, counting from the onset of menses, and the fertile phase is declared immediately if the E3G measurement reveals a concentration equal to or greater than a threshold concentration chosen in the range of about 25 to about 35 ng/ml.

摘要翻译： 提供对人类排卵周期的可育阶段发作的警告的方法，包括绝对或相对地测量分析物（例如雌二醇或其代谢物）的体液浓度的测量，其中如果在当前循环中进行浓度测量 大约在月经终止时，在28天的周期内，在排卵期前3天，平均人类女性受试者的体液中发现的体液浓度是典型的，目前的周期立即被宣告为 处于肥沃的阶段。 当分析物为E3G时，E3G浓度测量在当前周期的至少一个或数天4至7天进行，从月经开始计数，并且如果E3G测量显示浓度相等则立即声明可育阶段 达到或大于在约25至约35ng / ml范围内选择的阈值浓度。

公开(公告)号：US20060083658A1

公开(公告)日：2006-04-20

申请号：US11241250

申请日：2005-09-30

申请人： Michael Catt ,  Peter Lenko ,  Michael Pearson

发明人： Michael Catt ,  Peter Lenko ,  Michael Pearson

IPC分类号： G01N31/22

CPC分类号： G01N21/8483

摘要： A test kit for determining qualitatively or quantitatively the presence of one or more analytes in a fluid sample, comprising an assay device together with a reading device which engages with the assay device and wherein precisely located engagement of the assay device with the reading device is essential for accurate reading of the assay result, wherein precisely located engagement of the assay device with the reading device causes a ‘lock-and-key’ interaction, ie. a unique 3-dimensional interaction, between the assay device and reading initiation means of the reading device. Preferably the reading initiation means includes switch actuating means comprising at least one fixed projecting portion and at least one displaceable projecting portion, and a contact portion of the assay device casing comprises a recess shaped to accommodate the fixed projecting portion of the switch actuating means but not the displaceable projecting portion thereof, the contact portion also comprising an interface portion that contacts and displaces the displaceable portion of the switch actuating means when the fixed projecting portion is accommodated within the recess.

摘要翻译： 用于定性或定量地测定流体样品中一种或多种分析物的存在的测试试剂盒，其包含测定装置以及与测定装置接合的读取装置，并且其中精确定位的测定装置与读取装置的接合是必需的 为了准确地读取测定结果，其中测定装置与读取装置的精确定位的接合导致“锁定和键”的相互作用，即， 在测定装置和读取装置的读取启动装置之间的独特的三维相互作用。 优选地，读取启动装置包括开关致动装置，其包括至少一个固定突出部分和至少一个可移位的突出部分，并且测定装置壳体的接触部分包括成形为容纳开关致动装置的固定突出部分而不是 所述接触部分还包括接触部分，当所述固定突出部分容纳在所述凹部内时，所述接触部分接触并移动所述开关致动装置的可移位部分。

公开(公告)号：US06927064B1

公开(公告)日：2005-08-09

申请号：US09655355

申请日：2000-09-05

申请人： Michael Catt ,  Carole R. Cunningham ,  Paul H. C. Mundill ,  Michael E Prior ,  Stewart Wilson ,  Zhi G. Zhang

发明人： Michael Catt ,  Carole R. Cunningham ,  Paul H. C. Mundill ,  Michael E Prior ,  Stewart Wilson ,  Zhi G. Zhang

IPC分类号： A61B10/00 ,  A61D17/00

CPC分类号： A61D17/002 ,  A61B10/0012 ,  B01L2200/12

摘要： A fertility determining system employing hormone level measuring apparatus on selected days in a menstrual cycle to determine the levels of analytes, i.e., estrone-3-glucuronide (“E3G”) and luteinizing hormone (“LH”), in early morning urine. The fertility/infertility signalling algorithm relies upon data characterizing the user earlier in that menstrual cycle, and also upon her analyte pattern in past recent cycles. At a point in a menstrual cycle which is user-dependent, the early morning E3G urine level is compared against the lower E3G level earlier in the cycle. The beginning of the fertile period is signalled when a sufficient E3G increase occurs. The end of the fertile period (and, correspondingly, the reestablishment of a period requiring no contraception) is signalled a period after the LH surge. In the absence of an LH surge in any subject, the end of the fertile phase is signalled a period of time following the peak of the E3G urinary metabolite of estradiol.

摘要翻译： 在月经周期中选择天使用激素水平测量装置的生育力测定系统，以在早晨尿液中测定分析物的水平，即雌酮-3-葡糖苷酸（“E3G”）和促黄体激素（“LH”）。 生育/不育信号传递算法依赖于在该月经周期中更早地表达用户的数据，以及在最近的周期中她的分析物模式。 在用户依赖的月经周期中，早晨E3G尿液水平与周期早期的较低的E3G水平进行比较。 当发生足够的E3G增加时，信号显示了肥沃期的开始。 肥沃期结束（相应地，重新建立一个不需要避孕的时期）在LH激增后的一段时间内被告知。 在任何受试者没有LH波动的情况下，可育阶段的结束表明是E3G尿代谢产物峰值后的一段时间。

公开(公告)号：US20050171454A1

公开(公告)日：2005-08-04

申请号：US11079682

申请日：2005-03-14

申请人： Michael Catt ,  Carole Cunningham ,  Paul Mundill ,  Michael Prior ,  Stewart Wilson ,  Zhi Zhang

发明人： Michael Catt ,  Carole Cunningham ,  Paul Mundill ,  Michael Prior ,  Stewart Wilson ,  Zhi Zhang

IPC分类号： A61B10/00 ,  A61D17/00 ,  G01N33/48

CPC分类号： A61D17/002 ,  A61B10/0012 ,  B01L2200/12

摘要： A fertility determining system employing hormone level measuring apparatus on selected days in a menstrual cycle to determine the levels of analytes, i.e., estrone-3-glucuronide (“E3G”) and luteinizing hormone (“LH”), in early morning urine. The fertility/infertility signalling algorithm relies upon data characterizing the user earlier in that menstrual cycle, and also upon her analyte pattern in past recent cycles. At a point in a menstrual cycle which is user-dependent, the early morning E3G urine level is compared against the lower E3G level earlier in the cycle. The beginning of the fertile period is signalled when a sufficient E3G increase occurs. The end of the fertile period (and, correspondingly, the reestablishment of a period requiring no contraception) is signalled a period after the LH surge. In the absence of an LH surge in any subject, the end of the fertile phase is signalled a period of time following the peak of the E3G urinary metabolite of estradiol.

摘要翻译： 在月经周期中选择天使用激素水平测量装置的生育力测定系统，以在早晨尿液中测定分析物的水平，即雌酮-3-葡糖苷酸（“E3G”）和促黄体激素（“LH”）。 生育/不育信号传递算法依赖于在该月经周期中更早地表达用户的数据，以及在最近的周期中她的分析物模式。 在用户依赖的月经周期中，早晨E3G尿液水平与周期早期的较低的E3G水平进行比较。 当发生足够的E3G增加时，信号显示了肥沃期的开始。 肥沃期结束（相应地，重新建立一个不需要避孕的时期）在LH激增后的一段时间内被告知。 在任何受试者没有LH波动的情况下，可育阶段的结束表明是E3G尿代谢产物峰值后的一段时间。

公开(公告)号：US06234974B1

公开(公告)日：2001-05-22

申请号：US08772522

申请日：1996-12-24

申请人： Michael Catt ,  John Coley ,  Paul J Davis

发明人： Michael Catt ,  John Coley ,  Paul J Davis

IPC分类号： A61B1000

CPC分类号： G01N33/689 ,  A61B10/0012 ,  G01N33/743 ,  G01N33/76 ,  G01N2800/36

摘要： A method of monitoring the status of a current ovulation cycle of an individual human female subject, involving testing of the body fluid concentration of an analyte of significance in relation to the status of the ovulation cycle, such as urinary E3G, during at least part of the pre-ovulation phase of the current ovulation cycle of the individual subject, and identification from the results of such testing an analyte concentration change indicative of imminent ovulation, relative to an analyte concentration reference value that has been adapted to the individual human subject on the basis of analyte concentration test data obtained from the individual human subject during one or more previous ovulation cycles. Preferably testing for said analyte concentration during the current ovulation cycle is commenced a plurality of days (preferably at least 5) following the onset of menses but at least 2 numerical days in advance of the earliest numerical day on which actual ovulation has occurred in one or more previous ovulation cycles in the same individual subject.

摘要翻译： 一种监测个体人类女性受试者当前排卵周期状态的方法，包括在至少部分时间内测量相对于排卵周期状态（例如尿E3G）的有意义的分析物的体液浓度 个体受试者当前排卵周期的排卵前阶段以及相对于已经适应于个体受试者的分析物浓度参考值的来自这种测试结果的指示即将排卵的分析物浓度变化的鉴定 在一个或多个以前的排卵周期中从个体人受试者获得的分析物浓度测试数据的基础。 优选地，在当前排卵周期期间对所述分析物浓度的测试在月经开始之后开始多天（优选至少5天），但是在实际排卵发生在一个或多个之前的最早数字日之前的至少2个数天 在同一个体科目中更多的排卵周期。

公开(公告)号：US07534393B2

公开(公告)日：2009-05-19

申请号：US11079682

申请日：2005-03-14

申请人： Michael Catt ,  Carole R. Cunningham ,  Paul H. C. Mundill ,  Michael E. Prior ,  Stewart Wilson ,  Zhi G. Zhang

发明人： Michael Catt ,  Carole R. Cunningham ,  Paul H. C. Mundill ,  Michael E. Prior ,  Stewart Wilson ,  Zhi G. Zhang

IPC分类号： G01N33/48 ,  G01N21/00 ,  G01N31/00 ,  G01N31/22 ,  G01N33/00 ,  G01N15/06 ,  B01L1/00 ,  B01L3/00

CPC分类号： A61D17/002 ,  A61B10/0012 ,  B01L2200/12

摘要： A fertility determining system employing hormone level measuring apparatus on selected days in a menstrual cycle to determine the levels of analytes, i.e., estrone-3-glucuronide (“E3G”) and luteinizing hormone (“LH”), in early morning urine. The fertility/infertility signalling algorithm relies upon data characterizing the user earlier in that menstrual cycle, and also upon her analyte pattern in past recent cycles. At a point in a menstrual cycle which is user-dependent, the early morning E3G urine level is compared against the lower E3G level earlier in the cycle. The beginning of the fertile period is signalled when a sufficient E3G increase occurs. The end of the fertile period (and, correspondingly, the reestablishment of a period requiring no contraception) is signalled a period after the LH surge. In the absence of an LH surge in any subject, the end of the fertile phase is signalled a period of time following the peak of the E3G urinary metabolite of estradiol.

摘要翻译： 在月经周期中选择天使用激素水平测量装置的生育力测定系统，以在早晨尿液中测定分析物的水平，即雌酮-3-葡糖苷酸（“E3G”）和促黄体激素（“LH”）。 生育/不育信号传递算法依赖于在该月经周期中更早地表达用户的数据，以及在最近的周期中她的分析物模式。 在用户依赖的月经周期中，早晨E3G尿液水平与周期早期的较低的E3G水平进行比较。 当发生足够的E3G增加时，信号显示了肥沃期的开始。 肥沃期结束（相应地，重新建立一个不需要避孕的时期）在LH激增后的一段时间内被告知。 在任何受试者没有LH波动的情况下，可育阶段的结束表明是E3G尿代谢产物峰值后的一段时间。

公开(公告)号：US20080275348A1

公开(公告)日：2008-11-06

申请号：US12150679

申请日：2008-04-30

申请人： Michael Catt ,  Ming Li ,  Arthur Maurice Weightman

发明人： Michael Catt ,  Ming Li ,  Arthur Maurice Weightman

IPC分类号： A61B5/11 ,  A61B5/01 ,  A61B5/0205

CPC分类号： A61B5/222 ,  A61B5/0205 ,  A61B5/02055 ,  A61B5/1112 ,  A61B5/1118 ,  A61B5/1123 ,  A61B5/4866 ,  A61B5/726 ,  A61B5/7264 ,  A61B2503/10 ,  A61B2562/0219 ,  G01C22/006

摘要： In an apparatus and method for obtaining an indication of energy expenditure by a mammal during exercise, one or more movement transducers (1) each output a respective movement signal related to physical movement. A frequency analysis (3) is performed on at least one of the movement signals to obtain a frequency analysis result. Classification means (5) determines from the frequency analysis result, what class of physical movement is involved in the exercise. Selection means (7) selects a form of calculation according to a class determined by the classification means. A form of calculation selected by the selection means is applied (9) to at least one of the movement signals so as to obtain the energy expenditure indication.

摘要翻译： 在用于在运动期间获得哺乳动物的能量消耗的指示的装置和方法中，一个或多个运动换能器（1）各自输出与身体运动相关的相应运动信号。 对至少一个运动信号执行频率分析（3）以获得频率分析结果。 分类方法（5）根据频率分析结果确定运动中涉及到什么样的身体运动。 选择装置（7）根据由分类装置确定的类别选择计算形式。 将选择装置选择的计算形式（9）应用于至少一个运动信号，以获得能量消耗指示。