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    ORAL DRUG COMPLIANCE MONITORING USING MAGNETIC-FIELD SENSORS
    5.
    发明申请
    ORAL DRUG COMPLIANCE MONITORING USING MAGNETIC-FIELD SENSORS 审中-公开
    使用磁场传感器进行口服药物监测

    公开(公告)号：US20100322859A1

    公开(公告)日：2010-12-23

    申请号：US12297321

    申请日：2007-04-24

    申请人： Christopher M. Jones ,  Maysam Ghovanloo ,  Douglas P. White ,  Peter K. Mercure ,  Malcolm W. Warren, II

    发明人： Christopher M. Jones ,  Maysam Ghovanloo ,  Douglas P. White ,  Peter K. Mercure ,  Malcolm W. Warren, II

    IPC分类号： A61K49/00 ,  G01R33/12 ,  G01N33/15

    CPC分类号： A61B5/06 ,  A61B5/0002 ,  A61B5/4205 ,  A61B5/4833 ,  A61B5/4839 ,  A61B5/6822 ,  A61J3/007 ,  A61J2200/30

    摘要： A method to measure compliance with a pharmaceutical regimen, by the steps of: (a) ingesting a dose of a medication (10) into the gastrointestinal tract of a person, the dose of medication (10) comprising a drug formulation (13) and a permanent magnet (14); (b) as a result of the ingestion of step (a), detecting passage of the permanent magnet (14) past at least two magnetic field sensors (20) positioned apart from each other and adjacent to the gastrointestinal tract; and (c) measuring compliance with the pharmaceutical regimen by way of the detection of step (b). And, apparatus useful to measure compliance with a pharmaceutical regimen by detecting ingestion of a dose of medication (10) comprising a drug formulation (13) and a permanent magnet (14), the apparatus including at least two magnetic field sensors (20) positioned apart from each other on a necklace (22), each magnetic field sensor (20) being in electronic communication with a microprocessor for receiving signals from the magnetic field sensors (20) to determine the passage of a permanent magnet (14) between the magnetic field sensors (20).

    摘要翻译： 一种通过以下步骤测量药物制剂的顺应性的方法：（a）将剂量的药物（10）摄入人的胃肠道，包含药物制剂（13）的药物剂量（10）和 永久磁铁（14）; （b）作为步骤（a）摄取的结果，检测永磁体（14）经过位于彼此分开并邻近胃肠道的至少两个磁场传感器（20）的通道; 和（c）通过检测步骤（b）测量药物方案的顺应性。 以及用于通过检测摄取包含药物制剂（13）和永磁体（14）的药物剂量（10）来测量药物方案的依从性的装置，所述装置包括至少两个磁场传感器（20），其定位 在项链（22）上彼此分开，每个磁场传感器（20）与微处理器电子通信，用于接收来自磁场传感器（20）的信号，以确定永磁体（14）在磁性 场传感器（20）。

    ORAL DRUG CAPSULE COMPONENT INCORPORATING A COMMUNICATION DEVICE
    7.
    发明申请
    ORAL DRUG CAPSULE COMPONENT INCORPORATING A COMMUNICATION DEVICE 审中-公开
    包含通信设备的口腔药物胶囊组件

    公开(公告)号：US20080175898A1

    公开(公告)日：2008-07-24

    申请号：US12015201

    申请日：2008-01-16

    申请人： Christopher Michael Jones ,  Douglas Paul White ,  Peter K. Mercure

    发明人： Christopher Michael Jones ,  Douglas Paul White ,  Peter K. Mercure

    IPC分类号： A61K9/52

    CPC分类号： A61J3/007 ,  A61B5/0002 ,  A61B5/06 ,  A61B5/061 ,  A61B5/42 ,  A61B5/4833 ,  A61B5/4839 ,  A61J2200/30 ,  A61K9/0009 ,  A61K9/4808 ,  G06F19/3462

    摘要： An improved upper capsule portion (62) of an oral drug delivery capsule (60) that includes an upper capsule portion (62) and a lower cup shaped capsule portion (64), the lower cup shaped capsule portion (64) containing a medical formulation (66), the lower capsule portion (64) being made of a material that disperses in gastrointestinal fluid, the lower capsule portion (64) having a mouth, the upper capsule portion (62) dimensioned to engage with the mouth of the lower capsule portion (64). The improvement is the positioning of a communication device, such as an RFID tag (90), on or integrally with the upper capsule portion (62) so that the communication device can communicate that the oral drug delivery capsule has been ingested. An alternate embodiment with an improved lower capsule portion is also disclosed.

    摘要翻译： 一种包含上胶囊部分（62）和下杯形胶囊部分（64）的口服药物输送胶囊（60）的改进的上胶囊部分（62），所述下杯形胶囊部分（64）包含医用制剂 （66），所述下胶囊部（64）由分散在胃肠液中的材料制成，所述下胶囊部（64）具有口部，所述上胶囊部（62）的尺寸设定成与所述下胶囊 部分（64）。 改进之处在于，与上部胶囊部分（62）或与上部胶囊部分（62）一体地定位诸如RFID标签（90）的通信装置，使得通信装置能够通信口服药物递送胶囊被摄取。 还公开了具有改进的下胶囊部分的替代实施例。

    Structures Useful in Creating Composite Left-Hand-Rule Media
    8.
    发明申请
    Structures Useful in Creating Composite Left-Hand-Rule Media 审中-公开
    用于创建复合左手规则媒体的结构

    公开(公告)号：US20080105826A1

    公开(公告)日：2008-05-08

    申请号：US11795161

    申请日：2006-01-18

    申请人： Peter K. Mercure ,  Robert P. Haley ,  Chris P. Christenson

    发明人： Peter K. Mercure ,  Robert P. Haley ,  Chris P. Christenson

    IPC分类号： H01Q1/36 ,  G01N22/00

    CPC分类号： H01Q1/36 ,  H01Q11/08 ,  H01Q15/0086

    摘要： This invention relates to structures which display negative magnetic permeability in response to a relatively broad range of wavelengths. This invention further relates to manufacture of negative magnetic permeability or negative electric permittivity structures by rapid prototyping methods. Finally, this invention relates to structures which display negative permittivity and negative permeability and are open cell structures.

    摘要翻译： 本发明涉及响应于相对宽的波长范围显示负磁导率的结构。 本发明还涉及通过快速成型方法制造负磁导率或负电容率结构。 最后，本发明涉及显示负介电常数和负磁导率的结构，并且是开孔结构。

    Oscillatory systems and methods of synthesizing same
    9.
    发明授权
    Oscillatory systems and methods of synthesizing same 失效
    振荡系统及其合成方法

    公开(公告)号：US5280424A

    公开(公告)日：1994-01-18

    申请号：US705020

    申请日：1991-05-22

    申请人： Peter R. Rony ,  Peter K. Mercure

    发明人： Peter R. Rony ,  Peter K. Mercure

    IPC分类号： B01J19/00 ,  G05B23/02 ,  G06F15/46 ,  G05B13/02

    CPC分类号： B01J19/0006

    摘要： Methods of synthesizing stable oscillatory chemical systems from chemical systems having at least one output dynamically related to at least one input are provided. The output and input of the chemical system are selected such that a dynamic relation exists between the input/output pair. The chemical pair is then analyzed to determine whether the response of said output to a change in the input is a cumulative response or resilient response. If the input/output response relationship of the selected input/output pair is determined to be resilient, then the methods require connecting a feedback block between said output and said input, said feedback having non-linear dynamics and inverting preaction hysteresis characteristics, or optionally repeating the selection and analysis steps with the different input/output pair until said output exhibits a cumulative response to a change in the input. If the response is determined to be cumulative, the methods require connecting a feedback block between said chemical system output and said chemical system input, said feedback block having non-linear dynamics and inverting Schmitt trigger hysteresis characteristics.

    摘要翻译： 提供了从具有与至少一个输入动态相关的至少一个输出的化学系统合成稳定振荡化学系统的方法。 选择化学系统的输出和输入，使得输入/输出对之间存在动态关系。 然后分析化学对以确定所述输出对输入变化的响应是累积响应还是弹性响应。 如果所选择的输入/输出对的输入/输出响应关系被确定为具有弹性，那么所述方法需要在所述输出和所述输入之间连接反馈块，所述反馈具有非线性动力学和反转预置滞后特性，或者可选地 重复使用不同输入/输出对的选择和分析步骤，直到所述输出表现出对输入变化的累积响应。 如果响应被确定为累积的，则该方法需要连接所述化学系统输出和所述化学系统输入之间的反馈块，所述反馈块具有非线性动力学和反相施密特触发滞后特性。