公开(公告)号：US20070104764A1

公开(公告)日：2007-05-10

申请号：US10572016

申请日：2004-09-13

申请人： Ejner Jensen ,  Hans-Henrik Hogenhaug ,  Peter Hansen ,  Poul Pedersen ,  Per Mygind

发明人： Ejner Jensen ,  Hans-Henrik Hogenhaug ,  Peter Hansen ,  Poul Pedersen ,  Per Mygind

IPC分类号： A23K1/165 ,  C07K14/195 ,  C12P21/06 ,  C12N1/21

CPC分类号： C12N15/62 ,  A01K2217/05 ,  A23K20/147 ,  A23K20/189 ,  C07K14/4723 ,  C07K2319/00 ,  C07K2319/02 ,  C12N15/79 ,  C12Q1/025

摘要： The invention relates to the use of co-expression of an antimicrobial agent and an enzyme, with a view to improving yield and/or overall production economy. Examples of antimicrobial agents are antimicrobial peptides such as lactoferricins and antimicrobial enzymes such as lysozyme and glucose oxidase, and examples of enzymes are endoglucanase, xylanase, phytase, protease, galactanase, mannanase, dextranase, alpha-galactosidase, pectate lyase, alpha-amylase and glucoamylase. A fusion product comprising the antimicrobial agent and the enzyme and a cleavable linker is novel, and can be used in animal feed and animal feed additives. The invention also describes the use of a protection domain wherein at least 50% of the amino acid residues comprised in the peptide protection domain are D (Asp) and/or E (Glu). The protection or quenching domain serves to temporarily and reversibly inactivate the antimicrobial peptide during the expression.

摘要翻译： 本发明涉及抗微生物剂和酶的共表达的用途，以提高产量和/或总体生产经济性。 抗微生物剂的实例是抗微生物肽如乳铁蛋白和抗微生物酶如溶菌酶和葡萄糖氧化酶，酶的实例是内切葡聚糖酶，木聚糖酶，植酸酶，蛋白酶，半乳聚糖酶，甘露聚糖酶，葡聚糖酶，α-半乳糖苷酶，果胶酸裂解酶，α-淀粉酶和 葡糖淀粉酶。 包含抗微生物剂和酶以及可切割接头的融合产物是新颖的，并且可以用于动物饲料和动物饲料添加剂。 本发明还描述了保护结构域的用途，其中肽保护结构域中包含的至少50％的氨基酸残基是D（Asp）和/或E（Glu）。 保护或猝灭结构域用于在表达过程中临时和可逆地灭活抗微生物肽。

公开(公告)号：US20080044853A1

公开(公告)日：2008-02-21

申请号：US11571091

申请日：2005-06-20

申请人： Steen Jorgensen ,  Poul Pedersen

发明人： Steen Jorgensen ,  Poul Pedersen

IPC分类号： C12P21/00 ,  C07H21/00 ,  C12N1/00

CPC分类号： C12N9/52 ,  C12N15/67 ,  C12N15/902 ,  C12N2800/40 ,  C12N2830/20

摘要： The present invention relates to a method for constructing a host cell expressing a polypeptide of interest from at least two ORF's stably integrated onto the chromosome of the host cell comprising the steps of: a) providing the at least two ORF's encoding the same polypeptide, wherein the at least two DNA sequences of the ORF's differ in at least one position; b) integrating the at least two ORF's in the same orientation on the host cell chromosome.

摘要翻译： 本发明涉及构建表达目标多肽的宿主细胞的方法，其至少两个稳定整合到宿主细胞的染色体上的ORF包括以下步骤：a）提供编码相同多肽的至少两个ORF，其中 ORF的至少两个DNA序列在至少一个位置上不同; b）在宿主细胞染色体上以相同方向整合至少两个ORF。

公开(公告)号：US20050022522A1

公开(公告)日：2005-02-03

申请号：US10871962

申请日：2004-06-18

申请人： Poul Pedersen ,  Tom Rudolph ,  Lee Mahlum ,  Radoslaw Kornicki ,  Bjarne Schmidt

发明人： Poul Pedersen ,  Tom Rudolph ,  Lee Mahlum ,  Radoslaw Kornicki ,  Bjarne Schmidt

IPC分类号： B62D5/093 ,  B63H25/22 ,  F16D31/00

CPC分类号： B62D5/093 ,  B63H25/22

摘要： The invention concerns a hydraulic steering arrangement with a steering motor, a supply path between a pressure source and the steering motor, in which supply path a throttling device and a measuring motor are located, a return path between the steering motor and a pressure sink, in which return path a return throttle is located, and a bypass path, which connects the supply path and the return path on the pressure source end or the pressure sink end, respectively, and which has a bypass throttle. It is endeavoured to make such steering arrangements suitable for fast motorboats. For this purpose it is ensured that with a load on the steering motor the pressure drop over the bypass throttle is larger than the sum of the pressure drops between a point before the first throttle and a point after the last throttle of the throttling device.

摘要翻译： 本发明涉及一种具有转向电动机的液压转向装置，压力源和转向电动机之间的供应路径，其中节流装置和测量电动机所在的供给路径，转向电动机和压力传感器之间的返回路径， 其中返回路径设置有回流节气门，旁路路径分别连接在压力源端或压力沉降端上的供应路径和返回路径，并且具有旁路节气门。 制造适合快速摩托艇的转向装置是非常努力的。 为此目的，确保在转向电动机上的负载上，旁路节流阀上的压降大于第一节气门之前的点和节流装置的最后节流之后的点之间的压降之和。

公开(公告)号：US20070266647A1

公开(公告)日：2007-11-22

申请号：US11578746

申请日：2005-04-20

申请人： Poul Pedersen ,  Tommy Jensen

发明人： Poul Pedersen ,  Tommy Jensen

IPC分类号： A47B5/06

CPC分类号： A47B13/06 ,  A47B9/00

摘要： The invention refers to a telescoping frame assembly (1) for height adjustment adjacent a wall (23) comprising: bracket structure for structure load mounting; self-blocking telescoping columns for height adjustment; movement of telescoping columns synchronized by mechanical means and/or common control of individual actuators; one telescoping column part being wall-mounted with possible supporting foot; with: a separate main beam (42) of constant circumscribed profile for horizontal arrangement and having means (52, 53) along its length for positioning and fixation of both vertical telescoping columns and horizontal brackets, with freely selectable positions along the main beam (42); telescoping columns (43) as separate units with specific positioning and fixation means (49, 54) for mounting to the main beam (42) at the selected positions; and brackets (44) as separate units provided with specific positioning and fixation means (47, 48, 49, 50) for mounting to the main beam (42) at the selected positions. The invention also refers to the use of such an assembly for, e.g., the mounting of basins and tubs.

摘要翻译： 本发明涉及一种用于邻近墙壁（23）进行高度调节的伸缩框架组件（1），包括：用于结构承载安装的托架结构; 用于高度调节的自阻挡伸缩柱; 通过机械装置同步的伸缩柱的运动和/或各个致动器的共同控制; 一个可伸缩的柱部分是壁挂式的，具有可能的支撑脚; 具有：用于水平布置的恒定外接轮廓的单独的主梁（42），并且具有沿其长度的装置（52,53），用于定位和固定两个垂直伸缩柱和水平支架，沿主梁（42）可自由选择的位置 ）; 伸缩柱（43）作为具有特定定位和固定装置（49,54）的单独单元，用于在选定位置安装到主梁（42）; 和支架（44）作为单独的单元，设置有用于在选定位置安装到主梁（42）的特定定位和固定装置（47,48,49,50）。 本发明还涉及这种组件用于例如盆和盆的安装。