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    Shaped coils for transcranial magnetic stimulation
    2.
    发明授权
    Shaped coils for transcranial magnetic stimulation 有权

    公开(公告)号：US09381374B2

    公开(公告)日：2016-07-05

    申请号：US14853829

    申请日：2015-09-14

    申请人： Rio Grande Neurosciences, Inc.

    发明人： David J. Mishelevich ,  M. Bret Schneider

    IPC分类号： A61N2/00 ,  A61N2/02

    CPC分类号： A61N2/02 ,  A61N2/006

    摘要： Described herein are shaped coil TMS electromagnets formed by two bent magnetic coil loops joined at a vertex having an angle between the outer coil regions of the coils that is typically less than 120 degrees (e.g., between about 45 and about 70 degrees, 60 degrees, etc.). The vertex region shaped to optimize the magnetic field projected from the TMS electromagnet. For example, the vertex region may be horizontal or vertical. In some variations the vertex region is formed by re-arranging the conductive windings forming the two coils so that they are no longer arranged in the same columnar structure that they are in the other portions of the bent magnetic coil loops. These TMS electromagnets may be well suited for use in deep-brain Transcranial Magnetic Stimulation.

    VARIABLY CONFIGURABLE, ADAPTABLE ELECTRODE ARRAYS AND EFFECTUATING SOFTWARE, METHODS, AND SYSTEMS
    4.
    发明申请
    VARIABLY CONFIGURABLE, ADAPTABLE ELECTRODE ARRAYS AND EFFECTUATING SOFTWARE, METHODS, AND SYSTEMS 审中-公开
    可变配置，适配电极阵列和效能软件，方法和系统

    公开(公告)号：US20160206871A1

    公开(公告)日：2016-07-21

    申请号：US14083379

    申请日：2013-11-18

    申请人： Rio Grande Neurosciences, Inc.

    发明人： Michael Weisend

    IPC分类号： A61N1/04 ,  A61N1/36

    CPC分类号： A61N1/0476 ,  A61B5/0075 ,  A61B5/0476 ,  A61B5/0478 ,  A61B5/055 ,  A61B5/4064 ,  A61B5/4094 ,  A61B5/4812 ,  A61B5/4836 ,  A61N1/0456 ,  A61N1/0526 ,  A61N1/36025

    摘要： Electrical non-invasive brain stimulation (NIBS) delivers weak electrical currents to the brain via electrodes that are affixed to the scalp. NIBS can excite or inhibit the brain in areas that are impacted by that electrical current during and for a short time following stimulation. Electrical NIBS can be used to change brain structure in terms of increasing white matter integrity as measured by diffusion tensor imaging. Together the electrical NIBS can induce changes in brain structure and function. The present methods and devices are adaptable to and configurable for facilitating the enhancement of brain performance, and the treatment of neurological diseases and tissues. The present methods and devices are advantageously designed to utilize modern electrodes deployed with, inter alia, various spatial arrangements, polarities, and current strengths to target brain areas or networks to thereby enhance performance or deliver therapeutic interventions.

    摘要翻译： 电子非侵入性脑刺激（NIBS）通过固定在头皮上的电极向脑传递弱电流。 刺激后，短时间内，NIBS可以激发或抑制受到电流影响的区域的大脑。 根据扩散张量成像测量，电气NIBS可用于改变大脑结构，增加白质完整性。 电气NIBS一起可以引起大脑结构和功能的变化。 本发明的方法和装置适用于和配置以便于增强脑部的表现，以及神经系统疾病和组织的治疗。 本发明的方法和装置有利地被设计为利用部署了特别是各种空间布置，极性和电流强度的现代电极来靶向脑区域或网络，从而增强性能或递送治疗干预。

    Two-part pulsed electromagnetic field applicator for application of therapeutic energy
    9.
    发明授权
    Two-part pulsed electromagnetic field applicator for application of therapeutic energy 有权
    用于治疗能量的两部分脉冲电磁场​​施加器

    公开(公告)号：US09320913B2

    公开(公告)日：2016-04-26

    申请号：US14688602

    申请日：2015-04-16

    申请人： Rio Grande Neurosciences, Inc.

    发明人： Andre' A. Dimino ,  Matthew E. Drummer

    IPC分类号： A61N2/00 ,  A61N2/02 ,  A61N1/40

    CPC分类号： A61N2/02 ,  A41D13/1245 ,  A41D2400/32 ,  A42B1/242 ,  A47G9/00 ,  A47G9/10 ,  A61N1/0484 ,  A61N1/40

    摘要： Pulsed electromagnetic field (PEMF) apparatuses and methods of making and using them. In particular, described herein are two-part PEMF apparatuses that include a self-contained, lightweight, small, compact (e.g., in some variations, wearable) generator unit that is adapted to releasably and replaceably mate with an applicator unit. The generator unit typically includes a power source and a controller that generated PEMF waveforms to be applied, including the shape and timing of the PEMF waveforms. The applicator unit typically includes a radio frequency (RF) power amplifier, a loop antenna, and impedance matching circuitry for matching the impedances for the connection between the antenna loop and the RF power amplifier. Thus, the generator module may control the application of PEMF signals without requiring impedance matching between the separable generator unit and the applicator unit. The applicator unit can include a plurality of variable capacitors that can be used to tune the PEMF signals.

    摘要翻译： 脉冲电磁场​​（PEMF）设备及其制造和使用的方法。 特别地，这里描述的是两部分PEMF装置，其包括适于可释放地和可更换地与施加器单元配合的独立，轻便，小型，致密的（例如，在一些变型中，可佩戴的）发生器单元。 发电机单元通常包括产生要施加的PEMF波形的电源和控制器，包括PEMF波形的形状和定时。 施加器单元通常包括射频（RF）功率放大器，环形天线和阻抗匹配电路，用于匹配天线环路和RF功率放大器之间的连接的阻抗。 因此，发电机模块可以控制PEMF信号的应用，而不需要可分离发电机单元和施加器单元之间的阻抗匹配。 施加器单元可以包括可用于调谐PEMF信号的多个可变电容器。