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    Consumer food testing device providing remote monitoring
    1.
    发明授权
    Consumer food testing device providing remote monitoring 失效
    消费者食品检测设备提供远程监控

    公开(公告)号：US08211715B1

    公开(公告)日：2012-07-03

    申请号：US13296379

    申请日：2011-11-15

    申请人： Robert B. Royds

    发明人： Robert B. Royds

    IPC分类号： G01N33/53

    CPC分类号： G01N33/569 ,  B01L3/508 ,  B01L2300/023 ,  B01L2300/027 ,  B01L2300/06 ,  B01L2300/0663 ,  B01L2300/0825 ,  G01N21/8483 ,  G01N33/02 ,  G01N2223/618 ,  Y02A50/52 ,  Y10S436/807 ,  Y10T436/25125 ,  Y10T436/25375

    摘要： A consumer food testing device for testing for the presence of harmful contaminants in a food sample, includes a system for producing a visual cue upon detection of a harmful chemical, biological, and/or ionizing radiation contaminant; and a processing system responsive to the detection of a harmful contaminant, for transmitting the global position of the consumer testing device, the identity of the harmful contaminant, and the time and date to a remote monitoring facility.

    摘要翻译： 用于测试食品样品中有害污染物的存在的消费者食品测试装置包括用于在检测到有害化学，生物和/或电离辐射污染物时产生视觉提示的系统; 以及响应于有害污染物的检测，用于将消费者测试装置的全球位置，有害污染物的身份以及时间和日期传送到远程监视设施的处理系统。

    Consumer food testing device
    2.
    发明授权
    Consumer food testing device 有权
    消费者食品检测装置

    公开(公告)号：US07776266B2

    公开(公告)日：2010-08-17

    申请号：US12321287

    申请日：2009-01-20

    申请人： Robert B. Royds

    发明人： Robert B. Royds

    IPC分类号： C12Q1/68 ,  B01L3/00 ,  G01N33/53

    CPC分类号： G01N33/558 ,  G01N33/54366 ,  Y02A50/52 ,  Y10S436/807 ,  Y10T436/25125 ,  Y10T436/25375

    摘要： A food testing device for testing for the presence of harmful contaminants in a food sample, includes a vessel adapted for holding a liquefied food sample, a liquefier operatively associated with the vessel for converting an unliquefied food sample into a liquefied food sample, at least one test assay dispensable from the device, wherein the test assay includes at least one assay reagent having an affinity for at least one harmful contaminant, and capable of both detecting the presence of the harmful contaminant in the liquefied food sample, and producing a visual cue upon recognition of the harmful contaminant; and a radiation detector disposed proximately to the vessel for indicating the presence of ionizing radiation in the food sample at amounts exceeding normal background levels to detect the presence of a radioactive agent as the harmful contaminant.

    摘要翻译： 一种用于测试食品样品中有害污染物的存在的食品测试装置，包括适用于容纳液化食品样品的容器，与容器操作相关联的液化器，用于将未液化食品样品转化成液化食品样品，至少一个 测试测定法，其中测试测定包括至少一种对至少一种有害污染物具有亲和力的测定试剂，并且能够检测液化食品样品中有害污染物的存在，并产生视觉提示 识别有害污染物; 以及放置在容器附近的放射线检测器，用于以超过正常背景水平的量指示食物样品中存在电离辐射，以检测作为有害污染物的放射性试剂的存在。

    Abuse resistant transdermal drug delivery patch including a release-enhanced antagonist
    3.
    发明申请
    Abuse resistant transdermal drug delivery patch including a release-enhanced antagonist 审中-公开
    耐药性透皮药物递送贴片，包括释放增强拮抗剂

    公开(公告)号：US20120171277A1

    公开(公告)日：2012-07-05

    申请号：US12930310

    申请日：2011-01-03

    申请人： Robert B. Royds

    发明人： Robert B. Royds

    IPC分类号： A61K9/70 ,  A61P25/30

    CPC分类号： A61K9/7084 ,  A61K9/7092

    摘要： A transdermal drug delivery patch has an excipient matrix containing an agonist for administration across the skin of a user, with the matrix further containing a plurality of spaced apart hollow cilia filled with an antagonist, whereby if an abuser attempts to physically remove the agonist the cilia will break releasing the antagonist, or if the abuser attempts to use a solvent to remove the agonist the cilia will dissolve releasing the antagonist, thereby blocking the effect the abuser is attempting to attain by concentrating the agonist for oral ingestion or by hypodermic needle injection. The plurality of spaced apart hollow cilia further includes a release-enhancing agent in association with the antagonist for increasing the release rate of the antagonist.

    摘要翻译： 透皮药物递送贴剂具有赋形剂基质，其含有用于施用使用者皮肤的激动剂，所述基质还包含填充有拮抗剂的多个间隔开的中空纤毛，由此如果滥用者试图将激动剂物理除去纤毛 将会释放拮抗剂，或者如果滥用者试图使用溶剂去除激动剂，则纤毛会溶解释放拮抗剂，从而阻止滥用者通过浓缩激动剂进行口服摄取或通过皮下注射针注射而尝试达到的效果。 多个间隔开的中空纤毛还包括与拮抗剂相关联的释放增强剂以增加拮抗剂的释放速率。

    Transdermal patch
    4.
    发明申请
    Transdermal patch 审中-公开
    透皮贴片

    公开(公告)号：US20080008747A1

    公开(公告)日：2008-01-10

    申请号：US11482206

    申请日：2006-07-07

    申请人： Robert B. Royds

    发明人： Robert B. Royds

    IPC分类号： A61K9/70

    CPC分类号： A61K9/7084 ,  A61K9/703 ,  A61K9/7092

    摘要： A transdermal patch for administrating an agonist to a patient, where the transdermal patch includes an occlusive wall defining a reservoir with an open bottom end and an opposing top end, a matrix permeable to perspiration from the patient occupying the reservoir, wherein the matrix includes a first region having the agonist suspended therein for release through the bottom end of the reservoir to the patient, and a second region located at the top end of the reservoir, wherein the second region includes an antagonist associated with the agonist suspended therein and being configured to release the antagonist at the onset of imminent overdose of the agonist by the patient, a permeable adhesive layer covering at least a portion of the bottom end of the reservoir, the adhesive layer being adapted for maintaining the matrix in communication with the skin of the patient; and at least one visual indicator located at the top end of the reservoir, wherein the at least one visual indicator is adapted to undergo a visual change in the presence of the perspiration from the patient.

    摘要翻译： 一种用于向患者施用激动剂的透皮贴剂，其中所述透皮贴剂包括限定具有开放底端和相对顶端的储存器的闭塞壁，来自占据所述储存器的患者可渗出汗液的基质，其中所述基质包括 第一区域，其中悬浮在其中的激动剂通过储存器的底端释放到患者，以及位于储存器顶端的第二区域，其中第二区域包括与悬浮在其中的激动剂相关联的拮抗剂， 在患者即将过量的激动剂开始时释放拮抗剂，覆盖储存器底端的至少一部分的可渗透粘合剂层，粘合剂层适于保持基质与患者的皮肤连通 ; 以及位于储存器顶端的至少一个视觉指示器，其中所述至少一个视觉指示器适于在存在来自患者的汗液时经历视觉变化。

    Consumer food testing device
    6.
    发明授权
    Consumer food testing device 失效

    公开(公告)号：US07527765B2

    公开(公告)日：2009-05-05

    申请号：US11401726

    申请日：2006-04-11

    申请人： Robert B. Royds

    发明人： Robert B. Royds

    IPC分类号： C12Q1/68 ,  G01N21/00 ,  G01N15/06 ,  B01L3/00 ,  G01N30/02 ,  G01N23/06 ,  B01L11/00 ,  C12Q1/00 ,  C12M1/36 ,  C12M1/34 ,  C12M3/00 ,  G01N33/543

    CPC分类号： G01N33/558 ,  G01N33/54366 ,  Y02A50/52 ,  Y10S436/807 ,  Y10T436/25125 ,  Y10T436/25375

    摘要： A food testing device for testing for the presence of harmful contaminants in a food sample, includes a vessel adapted for holding a liquefied food sample, a liquefier operatively associated with the vessel for converting an unliquefied food sample into a liquefied food sample, at least one test assay dispensable from the device, wherein the test assay includes at least one assay reagent having an affinity for at least one harmful contaminant, and capable of both detecting the presence of the harmful contaminant in the liquefied food sample, and producing a visual cue upon recognition of the harmful contaminant; and a radiation detector disposed proximately to the vessel for indicating the presence of ionizing radiation in the food sample at amounts exceeding normal background levels to detect the presence of a radioactive agent as the harmful contaminant.

    ABUSE RESISTANT TRANSDERMAL DRUG DELIVERY PATCH INCLUDING A RELEASE-ENHANCED ANTAGONIST
    7.
    发明申请
    ABUSE RESISTANT TRANSDERMAL DRUG DELIVERY PATCH INCLUDING A RELEASE-ENHANCED ANTAGONIST 审中-公开
    耐药性透皮药物输送包括一个释放增强的拮抗剂

    公开(公告)号：US20120238970A1

    公开(公告)日：2012-09-20

    申请号：US13483646

    申请日：2012-05-30

    申请人： Robert B. Royds

    发明人： Robert B. Royds

    IPC分类号： A61M35/00

    CPC分类号： A61K9/7084 ,  A61K9/7092

    摘要： A transdermal drug delivery patch has an excipient matrix containing an agonist for administration across the skin of a user, with the matrix further containing a plurality of spaced apart hollow cilia filled with an antagonist, whereby if an abuser attempts to physically remove the agonist the cilia will break releasing the antagonist, or if the abuser attempts In use a solvent to remove the agonist the cilia will dissolve releasing the antagonist, thereby blocking the effect the abuser is attempting to attain by concentrating the agonist for oral ingestion or by hypodermic needle injection. The plurality of spaced apart hollow cilia further includes a release enhancing agent in association with the antagonist for increasing the release rate of the antagonist.

    摘要翻译： 透皮药物递送贴剂具有赋形剂基质，其含有用于施用使用者皮肤的激动剂，所述基质还包含填充有拮抗剂的多个间隔开的中空纤毛，由此如果滥用者试图将激动剂物理除去纤毛 会释放拮抗剂，或者如果滥用者试图使用溶剂去除激动剂，则纤毛会溶解释放拮抗剂，从而阻止滥用者通过浓缩激动剂进行口服摄取或通过皮下注射针注射而尝试达到的效果。 多个间隔开的中空纤毛还包括与拮抗剂相关联的释放增强剂以增加拮抗剂的释放速率。

    Consumer food testing device
    8.
    发明申请
    Consumer food testing device 有权
    消费者食品检测装置

    公开(公告)号：US20090136633A1

    公开(公告)日：2009-05-28

    申请号：US12321287

    申请日：2009-01-20

    申请人： Robert B. Royds

    发明人： Robert B. Royds

    IPC分类号： G01N33/02

    CPC分类号： G01N33/558 ,  G01N33/54366 ,  Y02A50/52 ,  Y10S436/807 ,  Y10T436/25125 ,  Y10T436/25375

    摘要： A food testing device for testing for the presence of harmful contaminants in a food sample, includes a vessel adapted for holding a liquefied food sample, a liquefier operatively associated with the vessel for converting an unliquefied food sample into a liquefied food sample, at least one test assay dispensable from the device, wherein the test assay includes at least one assay reagent having an affinity for at least one harmful contaminant, and capable of both detecting the presence of the harmful contaminant in the liquefied food sample, and producing a visual cue upon recognition of the harmful contaminant; and a radiation detector disposed proximately to the vessel for indicating the presence of ionizing radiation in the food sample at amounts exceeding normal background levels to detect the presence of a radioactive agent as the harmful contaminant.

    摘要翻译： 一种用于测试食品样品中有害污染物的存在的食品测试装置，包括适用于容纳液化食品样品的容器，与容器操作相关联的液化器，用于将未液化食品样品转化成液化食品样品，至少一个 测试测定法，其中测试测定包括至少一种对至少一种有害污染物具有亲和力的测定试剂，并且能够检测液化食品样品中有害污染物的存在，并产生视觉提示 识别有害污染物; 以及放置在容器附近的放射线检测器，用于以超过正常背景水平的量指示食物样品中存在电离辐射，以检测作为有害污染物的放射性试剂的存在。

    Transdermal drug delivery system
    9.
    发明授权
    Transdermal drug delivery system 失效
    透皮给药系统

    公开(公告)号：US5466465A

    公开(公告)日：1995-11-14

    申请号：US176396

    申请日：1993-12-30

    申请人： Robert B. Royds ,  John Lim ,  Joel D. Rosen

    发明人： Robert B. Royds ,  John Lim ,  Joel D. Rosen

    IPC分类号： A61K9/70 ,  A61F13/00

    CPC分类号： A61K9/7084 ,  A61K9/703 ,  A61K9/7092 ,  A61M35/006

    摘要： In a transdermal drug delivery system, encapsulation material used to coat drug granules controls the release of an active ingredient. The active ingredient is released into a water retaining matrix, which acts as a reservoir, and transdermal drug penetration is driven by the resulting concentration gradient. The delivery system is enclosed in a patch comprising a composite shell, which acts as an occlusive covering when attached to skin, thus enhancing the hydration of the skin area and fostering absorption of the drug. Visible change indicators incorporated into the system provide indicators at significant "landmarks" in the lifetime of the patch. Microcapsules used for the indicator may be formulated so that the penetration of moisture effects a color change at a time when the active ingredient is almost exhausted. This feature alerts to the user to the need for application of a replacement patch.

    摘要翻译： 在透皮药物递送系统中，用于包衣药物颗粒的包封材料控制活性成分的释放。 将活性成分释放到作为储存器的保水基质中，透皮药物穿透由所得浓度梯度驱动。 递送系统被包封在包括复合壳的贴片中，该复合壳在附着于皮肤时用作闭塞性覆盖物，从而增强皮肤区域的水合并促进药物的吸收。 纳入系统的可见变化指标提供了补丁生命周期中重要“地标”的指标。 用于指示剂的微胶囊可以配制成使得当活性成分几乎耗尽时，水分的渗透会影响颜色变化。 此功能可以提醒用户需要应用更换补丁。

    Method and system for maintaining HIPAA patient privacy requirements during auditing of electronic patient medical records
    10.
    发明授权
    Method and system for maintaining HIPAA patient privacy requirements during auditing of electronic patient medical records 失效
    在电子病人医疗记录审核过程中维护HIPAA患者隐私要求的方法和系统

    公开(公告)号：US07742933B1

    公开(公告)日：2010-06-22

    申请号：US12383445

    申请日：2009-03-24

    申请人： Robert B. Royds

    发明人： Robert B. Royds

    IPC分类号： G06F19/00

    CPC分类号： G06Q50/24 ,  G06F19/00 ,  G16H10/20 ,  G16H10/60

    摘要： A method and system for permitting a government agency or a medical research Institution to retain an independent Audit Agency to periodically audit a clinical trial testing the effect of experimental drugs on patients, being conducted by the Institution, to insure the audit conducted is in compliance with the privacy requirements of HIPAA. Prior to the audit, the Institution assembles individual electronic patient records relative to the clinical trial into an XML file in a discrete database, wherein each patient record has all personal information deleted, and such record is identified by a unique number or code assigned by the Institution. In turn, remote from the Institution, the Audit Agency transforms an appropriate search and indexing engine by adding to it libraries of text names, and synonyms, and constructs application programs containing the associated Protocol requirements and rules. The Audit Agency sends the transformed Search Engine to the Institution via the Internet or on CD's. The Institution runs the Search Engine against their database to produce a Compliance Report detailing all discrepancies found relative the Protocol course of medical treatment for each patient in the clinical trial, and sends the report to the Audit Agency. The Audit Agency processes the report to provide an Audit Report to Institution requesting comments, and if necessary, a corrective action plan.

    摘要翻译： 一种允许政府机构或医学研究机构保留独立审计机构的方法和系统，以定期审核试验药物对由该机构进行的患者的影响的临床试验，以确保进行的审核符合 HIPAA的隐私要求。 在审核之前，机构将相对于临床试验的各个电子病历记录组装成离散数据库中的XML文件，其中每个病人记录都删除了所有个人信息，并且这样的记录由唯一的号码或由 机构。 反过来，审计署又通过向其添加文本名称和同义词库，并构建包含相关协议要求和规则的应用程序，来转换适当的搜索和索引引擎。 审计署将转换的搜索引擎通过互联网或CD发送到机构。 机构根据其数据库运行搜索引擎，以生成符合性报告，详细列出临床试验中每个患者的医疗治疗方案相关的所有差异，并将该报告发送给审计机构。 审计署处理报告，向机构提交审计报告，要求提供意见，如有必要，提供纠正行动计划。