-
公开(公告)号：US20110082180A1
公开(公告)日：2011-04-07
申请号：US12898806
申请日：2010-10-06
IPC分类号： A61K31/423 , C07D413/08 , C12Q1/26 , A61P33/02 , A61P31/12 , A61P31/10 , A61P31/04 , A61P31/06 , A61P31/00
CPC分类号： A61K31/423 , C07D413/04 , C12Q1/26 , C12Q1/70 , Y02A50/402 , Y02A50/471 , Y02A50/478
摘要： The compounds disclosed herein are isoxazole derivatives that are useful as antimicrobial compounds, particularly as anti-bacterial compounds. The disclosed methods comprise incubating at least two different substrates in the presence of at least one oxygenase to provide the disclosed compounds, or to prepare and identify compounds that have antimicrobial activity.
摘要翻译： 本文公开的化合物是异恶唑衍生物，其可用作抗微生物化合物，特别是作为抗菌化合物。 所公开的方法包括在存在至少一种加氧酶的情况下孵育至少两种不同的底物以提供所公开的化合物，或制备和鉴定具有抗微生物活性的化合物。
-
公开(公告)号：US08975015B2
公开(公告)日：2015-03-10
申请号：US13102737
申请日：2011-05-06
IPC分类号： C12Q1/26 , C12Q1/70 , A61K31/423 , C07D413/04
CPC分类号： A61K31/423 , C07D413/04 , C12Q1/26 , C12Q1/70 , Y02A50/402 , Y02A50/471 , Y02A50/478
摘要： The compounds disclosed herein are isoxazole derivatives that are useful as antimicrobial compounds, particularly as anti-bacterial compounds. The disclosed methods comprise incubating at least two different substrates in the presence of at least one oxygenase to provide the disclosed compounds, or to prepare and identify compounds that have antimicrobial activity.
摘要翻译： 本文公开的化合物是异恶唑衍生物，其可用作抗微生物化合物，特别是作为抗菌化合物。 所公开的方法包括在存在至少一种加氧酶的情况下孵育至少两种不同的底物以提供所公开的化合物，或制备和鉴定具有抗微生物活性的化合物。
-
公开(公告)号：US06303366B1
公开(公告)日：2001-10-16
申请号：US09214751
申请日：1999-08-10
申请人： Robert Jon Steffan , Charles Whitman Condee , Kevin Rock McClay , Jennifer Diane Michelson , Mary F. DeFlaun
发明人： Robert Jon Steffan , Charles Whitman Condee , Kevin Rock McClay , Jennifer Diane Michelson , Mary F. DeFlaun
IPC分类号： C07C0000
CPC分类号： B09C1/10 , C02F2101/34 , Y10S435/863
摘要： Disclosed is a method for monitoring the degradation of methyl tert-butyl ether in a contaminated media which contains methyl tert-butyl ether and/or which is treated under conditions which cause the degradation of methyl tert-butyl ether into 2-hydroxy isobutyric acid comprising: (A) evaluating the treated contaminated media to determine the absence or presence therein of 2-hydroxy isobutyric acid; (B) based on such evaluation, determining whether the conditions should be modified; and (C) modifying such conditions as may be necessary. Disclosed also is a method for degrading an ether comprising contacting the ether with a microorganism that is effective in oxidizing propane or isopropanol and 2-hydroxy-isobutyric acid.
摘要翻译： 公开了一种监测甲基叔丁基醚在含有甲基叔丁基醚的污染介质中的降解和/或在使甲基叔丁基醚降解成2-羟基异丁酸的条件下进行处理的方法，所述方法包括 （A）评估经处理的污染介质以确定其中不含或存在2-羟基异丁酸; （B）根据此类评估，确定条件是否应予修改; 和（C）修改可能需要的条件。 还公开了降解醚的方法，包括使醚与有效氧化丙烷或异丙醇和2-羟基 - 异丁酸的微生物接触。
-
公开(公告)号：US5958757A
公开(公告)日：1999-09-28
申请号：US713992
申请日：1996-09-13
CPC分类号： C02F3/1231 , B09C1/10 , C02F3/34 , C12P5/02 , C12P5/023 , B09C2101/00 , C02F2209/06 , C02F2209/22 , Y02E50/343 , Y02W10/15 , Y10S435/874
摘要： Saturated aliphatic halocarbons, including environmental contaminants, are degraded to innocuous, environmentally acceptable compounds by contact, either in situ or in a bioreactor, with microorganisms that produce aromatic oxygenases, preferably with use of a co-substrate, for example, phenol, toluene, benzene, ethylbenzene and xylene, including the provision of novel bacteria that produce aromatic oxygenases, and new recombinant microorganisms that contain cloned aromatic oxygenase genes, examples of saturated aliphatic halocarbon that may be degraded to innocuous compounds being chloroform; bromoform; 1,2-dichloroethane; 1,2-dibromoethane; monochloroethane and monobromoethane.
摘要翻译： 包括环境污染物在内的饱和脂肪族卤代烃通过原位或生物反应器与产生芳族加氧酶的微生物接触，优选使用共同底物，例如苯酚，甲苯， 苯，乙苯和二甲苯，包括提供产生芳族加氧酶的新细菌，以及含有克隆的芳族加氧酶基因的新的重组微生物，可被降解成无害化合物的饱和脂族卤代烃的例子是氯仿; 溴仿; 1,2-二氯乙烷; 1,2-二溴乙烷; 一氯乙烷和一溴乙烷。
-
公开(公告)号：US20110212435A1
公开(公告)日：2011-09-01
申请号：US13102737
申请日：2011-05-06
CPC分类号： A61K31/423 , C07D413/04 , C12Q1/26 , C12Q1/70 , Y02A50/402 , Y02A50/471 , Y02A50/478
摘要： The compounds disclosed herein are isoxazole derivatives that are useful as antimicrobial compounds, particularly as anti-bacterial compounds. The disclosed methods comprise incubating at least two different substrates in the presence of at least one oxygenase to provide the disclosed compounds, or to prepare and identify compounds that have antimicrobial activity.
摘要翻译： 本文公开的化合物是异恶唑衍生物，其可用作抗微生物化合物，特别是作为抗菌化合物。 所公开的方法包括在存在至少一种加氧酶的情况下孵育至少两种不同的底物以提供所公开的化合物，或制备和鉴定具有抗微生物活性的化合物。
-
公开(公告)号：US07973065B2
公开(公告)日：2011-07-05
申请号：US12898806
申请日：2010-10-06
IPC分类号： A61K31/423 , C07D413/04
CPC分类号： A61K31/423 , C07D413/04 , C12Q1/26 , C12Q1/70 , Y02A50/402 , Y02A50/471 , Y02A50/478
摘要： The compounds disclosed herein are isoxazole derivatives that are useful as antimicrobial compounds, particularly as anti-bacterial compounds. The disclosed methods comprise incubating at least two different substrates in the presence of at least one oxygenase to provide the disclosed compounds, or to prepare and identify compounds that have antimicrobial activity.
摘要翻译： 本文公开的化合物是异恶唑衍生物，其可用作抗微生物化合物，特别是作为抗菌化合物。 所公开的方法包括在存在至少一种加氧酶的情况下孵育至少两种不同的底物以提供所公开的化合物，或制备和鉴定具有抗微生物活性的化合物。
-
公开(公告)号：US5814514A
公开(公告)日：1998-09-29
申请号：US677516
申请日：1996-07-10
申请人： Robert Jon Steffan , Charles Whitman Condee , Kevin Rock McClay , Jennifer Diane Michelson , Mary F. DeFlaun
发明人： Robert Jon Steffan , Charles Whitman Condee , Kevin Rock McClay , Jennifer Diane Michelson , Mary F. DeFlaun
CPC分类号： A62D3/02 , B09C1/10 , C02F3/34 , C12P1/00 , A62D2101/28 , Y10S435/863
摘要： The present invention is directed to a method for degrading an undesirable ether-based environmental contaminant by contacting the ether with a propane-oxidizing microorganism or with an isopropanol-oxidizing microorganism to convert the ether to innocuous compounds which are environmentally acceptable, including treating the ether-based contaminants in situ or removing them from the contaminated site for treatment in a bioreactor. Examples of ether-based compounds which can be degraded are tertiary butyl ethers of the type utilized as gasoline oxygenates, for example, methyl tert-butyl ether, ethyl tert-butyl ether, and methyl tert-amyl ether and also ether solvents, for example, tetrahydrofuran.
摘要翻译： 本发明涉及一种通过使醚与丙烷氧化微生物或异丙醇氧化微生物接触来降解不期望的基于醚的环境污染物的方法，以将醚转化为无害环境可接受的化合物，包括处理醚 的污染物，或将其从污染场地中除去，以便在生物反应器中进行处理。 可以被降解的醚基化合物的实例是用作汽油含氧化合物的类型的叔丁基醚，例如甲基叔丁基醚，乙基叔丁基醚和甲基叔戊基醚，以及醚溶剂，例如 ，四氢呋喃。
-
-
-
-
-
-
搜索结果
7 条记录 (耗时 0.021 秒)
