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    Needle assemblies for wet/dry automatic injectors
    1.
    发明授权
    Needle assemblies for wet/dry automatic injectors 有权
    湿/干自动注射器针组件

    公开(公告)号：US08568367B2

    公开(公告)日：2013-10-29

    申请号：US11698937

    申请日：2007-01-26

    申请人： Steven M. Griffiths ,  Robert L. Hill

    发明人： Steven M. Griffiths ,  Robert L. Hill

    IPC分类号： A61M37/00 ,  A61M5/00 ,  A61M5/315

    CPC分类号： A61M5/31596 ,  A61M5/19 ,  A61M5/2033 ,  A61M5/2066 ,  A61M5/284 ,  A61M5/286 ,  A61M5/3145 ,  A61M5/31513 ,  A61M5/3202 ,  A61M5/3293 ,  A61M5/34 ,  A61M5/343 ,  A61M5/348 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2005/287 ,  A61M2005/3106 ,  A61M2005/3131 ,  A61M2005/3132 ,  A61M2202/064 ,  A61M2205/7536 ,  A61M2205/7545

    摘要： An automatic medicament injector having a compartment for a dry medicament component and a compartment for a wet medicament component. The two compartments are separated by a seal structure that converts from a sealing condition to a mixing condition when the device is activated. The seal structure includes a wiper that scrapes the interior walls in the dry component compartment to prevent the dry component from accumulating at the seal/glass interface. A tapered insert funnels the mixed medicament components to an attached needle assembly, but can be removed when the device is filled. A filter is provided between the medicament compartments and the needle assembly. A chamber between the filter and the needle allows for better flow through the filter. An actuation assembly drives the seal structure into the mixing condition and forces the mixed medicament through the needle and into the user.

    摘要翻译： 一种自动药物注射器，其具有用于干药物组分的隔室和用于湿药物组分的隔室。 两个隔室由密封结构分开，当设备被激活时，该密封结构从密封条件转变为混合状态。 密封结构包括擦拭干燥部件隔室中的内壁以防止干燥部件在密封/玻璃界面处积聚的刮水器。 锥形插入件将混合的药物组分漏出到附接的针组件，但是当装置被填充时可以将其移除。 在药剂隔室和针组件之间设置过滤器。 过滤器和针之间的腔室可以更好地流过过滤器。 致动组件驱动密封结构进入混合状态，并迫使混合药物穿过针头进入使用者。

    Flow-path inserts for wet/dry automatic injectors
    3.
    发明授权
    Flow-path inserts for wet/dry automatic injectors 有权
    湿/干自动注射器的流路插入件

    公开(公告)号：US07608055B2

    公开(公告)日：2009-10-27

    申请号：US11698964

    申请日：2007-01-26

    申请人： Steven M. Griffiths ,  Robert L. Hill

    发明人： Steven M. Griffiths ,  Robert L. Hill

    IPC分类号： A61M37/00 ,  A61M5/00

    CPC分类号： A61M5/31596 ,  A61M5/19 ,  A61M5/2033 ,  A61M5/2066 ,  A61M5/284 ,  A61M5/286 ,  A61M5/3145 ,  A61M5/31513 ,  A61M5/3202 ,  A61M5/3293 ,  A61M5/34 ,  A61M5/343 ,  A61M5/348 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2005/287 ,  A61M2005/3106 ,  A61M2005/3131 ,  A61M2005/3132 ,  A61M2202/064 ,  A61M2205/7536 ,  A61M2205/7545

    摘要： An automatic medicament injector having a compartment for a dry medicament component and a compartment for a wet medicament component. The two compartments are separated by a seal structure that converts from a sealing condition into a mixing condition when the device is activated. The seal structure includes a wiper that scrapes the interior walls in the dry component compartment to prevent the dry component from accumulating at the seal/glass interface. A tapered insert funnels the mixed medicament components to an attached needle assembly, but can be removed when the device is filled. A filter is provided between the medicament compartments and the needle assembly. A chamber between the filter and the needle allows for better flow through the filter. An actuation assembly drives the seal structure into the mixing condition and forces the mixed medicament through the needle and into the user.

    摘要翻译： 一种自动药物注射器，其具有用于干药物组分的隔室和用于湿药物组分的隔室。 两个隔间由密封结构隔开，密封结构在装置被激活时从密封条件转换成混合状态。 密封结构包括擦拭干燥部件隔室中的内壁以防止干燥部件在密封/玻璃界面处积聚的刮水器。 锥形插入件将混合的药物组分漏出到附接的针组件，但是当装置被填充时可以将其移除。 在药剂隔室和针组件之间设置过滤器。 过滤器和针之间的腔室可以更好地流过过滤器。 致动组件驱动密封结构进入混合状态，并迫使混合药物穿过针头进入使用者。

    Wet/dry automatic injector assembly
    4.
    发明授权
    Wet/dry automatic injector assembly 失效
    湿/干自动注射器组件

    公开(公告)号：US06953445B2

    公开(公告)日：2005-10-11

    申请号：US09971768

    申请日：2001-10-09

    申请人： John G. Wilmot ,  Robert L. Hill ,  John Whittier

    发明人： John G. Wilmot ,  Robert L. Hill ,  John Whittier

    IPC分类号： A61J1/05 ,  A61M5/20 ,  A61M5/28 ,  A61M5/31 ,  A61M5/32 ,  A61M5/34 ,  A61M37/00 ,  A61M5/00

    CPC分类号： A61M5/343 ,  A61M5/2033 ,  A61M5/2066 ,  A61M5/286 ,  A61M5/3145 ,  A61M5/34 ,  A61M2005/206 ,  A61M2005/2073

    摘要： The present invention is directed to an automatic injection device containing a pre-loaded charge of medicament for automatically self-administering the medicament upon actuation thereof. The automatic injection device includes a housing assembly having an interior chamber, an activation assembly and a needle assembly for dispensing a dissolved medicament to a user. A dry compartment for storing a predetermined dry charge of dry medicament is located within the interior chamber. A wet compartment for storing a predetermined amount of liquid injection solution is also located within the interior chamber. A separation assembly separates the dry compartment from the wet compartment. The separation assembly prevents transfer of the liquid injection solution from the wet compartment to the dry compartment prior to activation of the automatic injection device. One or more medicament support assemblies located within the dry compartment prevent the passage of undissolved medicament from the dry compartment.

    摘要翻译： 本发明涉及一种自动注射装置，其包含用于在致动药剂时自动给药的药物的预加载药物。 自动注射装置包括壳体组件，其具有内部腔室，激活组件和用于将溶解的药物分配给使用者的针组件。 用于存储预定的干药物的干燥室的干燥室位于内部室内。 用于存储预定量的液体注射溶液的湿室也位于内部室内。 分离组件将干燥室与湿室隔开。 分离组件防止在启动自动注射装置之前将液体注射溶液从湿室转移到干燥室。 位于干燥室内的一个或多个药物支持组件防止未溶解的药物从干燥室中通过。

    Method and apparatus for the production of glass filaments
    6.
    发明授权
    Method and apparatus for the production of glass filaments 失效
    用于生产玻璃丝的方法和设备

    公开(公告)号：US4662922A

    公开(公告)日：1987-05-05

    申请号：US706061

    申请日：1985-03-01

    申请人： Robert L. Hill ,  Douglas J. Eberle

    发明人： Robert L. Hill ,  Douglas J. Eberle

    IPC分类号： C03B37/02 ,  C03B37/085

    CPC分类号： C03B37/0206 ,  C03B37/0213 ,  C03B37/0216 ,  Y02P40/57

    摘要： A continuous glass fiber forming system incorporates a high energy stream of fluid to establish and control induced air flow from around the feeder to (1) substantially simulate the induction of air into the filament forming region in the absence of filament attenuation like that induced during attenuation and/or (2) increase the amount of heat removal effected during attenuation of the filaments.

    摘要翻译： 连续的玻璃纤维形成系统结合了高能量的流体流，以建立和控制来自进料器周围的诱导空气流，（1）在不存在如衰减期间诱发的灯丝衰减的情况下，基本上模拟空气进入灯丝形成区域的空气 和/或（2）增加在细丝衰减期间所进行的热去除量。

    Seal structures for wet/dry automatic injectors
    7.
    发明授权
    Seal structures for wet/dry automatic injectors 有权
    湿/干自动注射器的密封结构

    公开(公告)号：US08506526B2

    公开(公告)日：2013-08-13

    申请号：US13468421

    申请日：2012-05-10

    申请人： Steven M. Griffiths ,  Robert L. Hill

    发明人： Steven M. Griffiths ,  Robert L. Hill

    IPC分类号： A61M37/00

    CPC分类号： A61M5/31596 ,  A61M5/19 ,  A61M5/2033 ,  A61M5/2066 ,  A61M5/284 ,  A61M5/286 ,  A61M5/3145 ,  A61M5/31513 ,  A61M5/3202 ,  A61M5/3293 ,  A61M5/34 ,  A61M5/343 ,  A61M5/348 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2005/287 ,  A61M2005/3106 ,  A61M2005/3131 ,  A61M2005/3132 ,  A61M2202/064 ,  A61M2205/7536 ,  A61M2205/7545

    摘要： An automatic injection device including a housing, a chamber with a first compartment and a second compartment, and a seal structure between the compartments. The seal structure is initially in a sealing condition that seals the first compartment from the second compartment, where the seal includes a plug and an outer sealing member. The plug is slidably movable within the outer sealing member to convert the seal structure from the sealing condition to a mixing condition by opening a path between the first compartment and the second compartment. The automatic injection device also includes a needle assembly and an activation assembly. Activation of the activation assembly causes (1) pressurization of the first compartment, (2) the seal structure to convert from the sealing condition to the mixing condition, and (3) the first and second medicament components to be mixed and forced through the needle assembly.

    摘要翻译： 一种自动注射装置，包括壳体，具有第一隔室的腔室和第二隔室，以及隔室之间的密封结构。 密封结构最初处于将第一隔室与第二隔室密封的密封状态，其中密封件包括塞子和外密封件。 塞子可在外部密封件内滑动移动，以通过打开第一隔室和第二隔室之间的路径将密封结构从密封状态转换成混合状态。 自动注射装置还包括针组件和激活组件。 激活组件的激活导致（1）第一隔室的加压，（2）密封结构从密封条件转化为混合状态，以及（3）要混合并强制通过针的第一和第二药物成分 部件。

    Seal Structures For Wet/Dry Automatic Injectors
    8.
    发明申请
    Seal Structures For Wet/Dry Automatic Injectors 有权
    湿/干自动注射器的密封结构

    公开(公告)号：US20120220930A1

    公开(公告)日：2012-08-30

    申请号：US13468421

    申请日：2012-05-10

    申请人： Steven M. GRIFFITHS ,  Robert L. Hill

    发明人： Steven M. GRIFFITHS ,  Robert L. Hill

    IPC分类号： A61M5/31

    CPC分类号： A61M5/31596 ,  A61M5/19 ,  A61M5/2033 ,  A61M5/2066 ,  A61M5/284 ,  A61M5/286 ,  A61M5/3145 ,  A61M5/31513 ,  A61M5/3202 ,  A61M5/3293 ,  A61M5/34 ,  A61M5/343 ,  A61M5/348 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2005/287 ,  A61M2005/3106 ,  A61M2005/3131 ,  A61M2005/3132 ,  A61M2202/064 ,  A61M2205/7536 ,  A61M2205/7545

    摘要： An automatic injection device including a housing, a chamber with a first compartment and a second compartment, and a seal structure between the compartments. The seal structure is initially in a sealing condition that seals the first compartment from the second compartment, where the seal includes a plug and an outer sealing member. The plug is slidably movable within the outer sealing member to convert the seal structure from the sealing condition to a mixing condition by opening a path between the first compartment and the second compartment. The automatic injection device also includes a needle assembly and an activation assembly. Activation of the activation assembly causes (1) pressurization of the first compartment, (2) the seal structure to convert from the sealing condition to the mixing condition, and (3) the first and second medicament components to be mixed and forced through the needle assembly.

    摘要翻译： 一种自动注射装置，包括壳体，具有第一隔室的腔室和第二隔室，以及隔室之间的密封结构。 密封结构最初处于将第一隔室与第二隔室密封的密封状态，其中密封件包括塞子和外密封件。 塞子可在外部密封件内滑动移动，以通过打开第一隔室和第二隔室之间的路径将密封结构从密封状态转换成混合状态。 自动注射装置还包括针组件和激活组件。 激活组件的激活导致（1）第一隔室的加压，（2）密封结构从密封条件转化为混合状态，以及（3）要混合并强制通过针的第一和第二药物成分 部件。

    Autoinjector With Needle Depth Adapter
    10.
    发明申请
    Autoinjector With Needle Depth Adapter 审中-公开
    自动注射器与针深度适配器

    公开(公告)号：US20100292643A1

    公开(公告)日：2010-11-18

    申请号：US12844279

    申请日：2010-07-27

    申请人： John G. Wilmot ,  Robert L. Hill

    发明人： John G. Wilmot ,  Robert L. Hill

    IPC分类号： A61M5/46

    CPC分类号： A61M5/24 ,  A61M5/2033 ,  A61M5/3202 ,  A61M5/46 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2005/3143 ,  A61M2005/3267

    摘要： An autoinjector useful for, inter alia, providing an injection of liquid medicament is uniquely capable of providing injections, utilizes a needle depth adapter to provide injection depths with a combination of accuracy and precision not heretofore seen. In addition, the autoinjector with needle depth adapter can include a variety of size needle depth adapters to provide an autoinjector of varying, precise injection depths and which can be readily and easily manufactured. The autoinjector includes a housing, cartridge assembly, needle, needle depth adapter, and power providing assembly.

    摘要翻译： 用于特别是提供液体药物注射的自动注射器独特地能够提供注射，利用针深度适配器来提供没有以前看到的准确度和精度的组合的注射深度。 此外，具有针深度适配器的自动注射器可以包括各种尺寸的针深度适配器，以提供具有变化的精确注射深度的自动注射器，并且其可容易且容易地制造。 自动注射器包括壳体，筒组件，针，针深度适配器和动力提供组件。