-
1.发明申请SUBSTITUTED PIPERIDINO PHENYLOXAZOLIDINONES HAVING ANTIMICROBIAL ACTIVITY WITH IMPROVED IN VIVO EFFICACY 有权具有改善活体功效的抗微生物活性的替代哌啶苯并噻唑啉酮公开(公告)号：US20100144735A1
公开(公告)日：2010-06-10
申请号：US12705258
申请日：2010-02-12
Applicant: Prasad Keshav Deshpande , Milind Dattatraya Sindkhedkar , Mahesh Shriram Phansalkar , Ravindra Dattatraya Yeole , Shrikant Vinayak Gupte , Yati Chugil , Nitin Shetty , Sachin Subhash Bhagwat , Milind Chintaman Shukla , Noel John De Souza , Mahesh Vithalbhai Patel
Inventor： Prasad Keshav Deshpande , Milind Dattatraya Sindkhedkar , Mahesh Shriram Phansalkar , Ravindra Dattatraya Yeole , Shrikant Vinayak Gupte , Yati Chugil , Nitin Shetty , Sachin Subhash Bhagwat , Milind Chintaman Shukla , Noel John De Souza , Mahesh Vithalbhai Patel
IPC: A61K31/5377 , A61K31/496 , A61K31/438 , A61K31/4545 , A61K31/454 , C07D498/10 , C07D495/10 , C07D491/113 , C07D413/10 , A61P31/04 , C07D491/107 , C07D413/14 , C07D513/10
CPC classification number: C07D491/10 , C07D413/10 , C07D413/14 , C07D495/10 , C07D497/10 , C07D513/10
Abstract: The present invention provides agents having antimicrobial activity for preventing and treating infectious diseases. Thus, the present invention provides novel substituted piperidino phenyloxazolidinone derivatives, processes for making compounds as well as antimicrobial compositions containing said derivatives as active ingredients and methods of treating bacterial infections with the said derivatives.
Abstract translation: 本发明提供具有预防和治疗感染性疾病的抗微生物活性的试剂。 因此，本发明提供新的取代的哌啶子基苯基恶唑烷酮衍生物，制备化合物的方法以及含有所述衍生物作为活性成分的抗微生物组合物以及用所述衍生物治疗细菌感染的方法。
-
2.发明授权Pharmaceutical compositions comprising beta-lactam antibiotic, sulbactam and beta-lactamase inhibitor 有权包含β-内酰胺抗生素，舒巴坦和β-内酰胺酶抑制剂的药物组合物公开(公告)号：US09095594B2
公开(公告)日：2015-08-04
申请号：US14114207
申请日：2011-10-04
Applicant: Sachin Subhash Bhagwat , Mahesh Vithalbhai Patel
Inventor： Sachin Subhash Bhagwat , Mahesh Vithalbhai Patel
IPC: A61K31/00 , A61K31/546 , A61K45/06 , A61K31/4188 , A61K31/424 , A61K31/43 , A61K31/431 , A61K31/439
CPC classification number: A61K31/546 , A61K31/4188 , A61K31/424 , A61K31/43 , A61K31/431 , A61K31/439 , A61K45/06 , A61K2300/00
Abstract: Pharmaceutical compositions and methods for treating or preventing bacterial infections are disclosed. The pharmaceutical compositions typically comprise pharmaceutically effective amount of: (a) at least one beta-lactam antibiotic or a pharmaceutically acceptable salt thereof, (b) sulbactam or a pharmaceutically acceptable salt thereof, and (c) at least one beta-lactamase inhibitor or a pharmaceutically acceptable salt thereof, with the provision that the beta-lactamase inhibitor is not sulbactam.
Abstract translation: 公开了用于治疗或预防细菌感染的药物组合物和方法。 药物组合物通常包含药学有效量的：（a）至少一种β-内酰胺抗生素或其药学上可接受的盐，（b）舒巴坦或其药学上可接受的盐，和（c）至少一种β-内酰胺酶抑制剂或 其药学上可接受的盐，其条款是β-内酰胺酶抑制剂不是舒巴坦。
-
3.发明申请Pharmaceutical Compositions Comprising Beta-Lactam Antibiotic, Sulbactam and Beta-Lactamase Inhibitor 有权包含β-内酰胺抗生素，舒巴坦和β-内酰胺酶抑制剂的药物组合物公开(公告)号：US20140213566A1
公开(公告)日：2014-07-31
申请号：US14114207
申请日：2011-10-04
Applicant: Sachin Subhash Bhagwat , Mahesh Vithalbhai Patel
Inventor： Sachin Subhash Bhagwat , Mahesh Vithalbhai Patel
IPC: A61K31/546 , A61K31/439 , A61K31/43
CPC classification number: A61K31/546 , A61K31/4188 , A61K31/424 , A61K31/43 , A61K31/431 , A61K31/439 , A61K45/06 , A61K2300/00
Abstract: Pharmaceutical compositions and methods for treating or preventing bacterial infections are disclosed. The pharmaceutical compositions typically comprise pharmaceutically effective amount of: (a) at least one beta-lactam antibiotic or a pharmaceutically acceptable salt thereof, (b) sulbactam or a pharmaceutically acceptable salt thereof, and (c) at least one beta-lactamase inhibitor or a pharmaceutically acceptable salt thereof, with the provision that the beta-lactamase inhibitor is not sulbactam.
Abstract translation: 公开了用于治疗或预防细菌感染的药物组合物和方法。 药物组合物通常包含药学有效量的：（a）至少一种β-内酰胺抗生素或其药学上可接受的盐，（b）舒巴坦或其药学上可接受的盐，和（c）至少一种β-内酰胺酶抑制剂或 其药学上可接受的盐，其条款是β-内酰胺酶抑制剂不是舒巴坦。
-
公开(公告)号：US20140162995A1
公开(公告)日：2014-06-12
申请号：US14111627
申请日：2011-08-01
Applicant: Sachin Subhash Bhagwat , Mohammad Alam Jafri , Mahesh Vithalbhai Patel
Inventor： Sachin Subhash Bhagwat , Mohammad Alam Jafri , Mahesh Vithalbhai Patel
IPC: A61K31/431 , A61K31/546
Abstract: A pharmaceutical composition comprising antibacterial agent and tazobactam, wherein the ratio of tazobactam to the antibacterial agent in the composition is in the range of from about 0.5 to about 2 gram of tazobactam per gram of the antibacterial agent, are disclosed.
Abstract translation: 公开了包含抗菌剂和他唑巴坦的药物组合物，其中组合物中他唑巴坦与抗菌剂的比例为约0.5至约2克的他唑巴坦/克抗菌剂。
-
公开(公告)号：US20130296228A1
公开(公告)日：2013-11-07
申请号：US13867452
申请日：2013-04-22
Applicant: Mahesh Vithalbhai PATEL , Sachin Subhash Bhagwat , Mohammad Alam Jafri
Inventor： Mahesh Vithalbhai PATEL , Sachin Subhash Bhagwat , Mohammad Alam Jafri
IPC: A61K38/12 , A61K31/7052 , A61K31/65 , A61K31/438 , A61K31/431 , A61K31/4375 , A61K31/496
CPC classification number: A61K38/12 , A61K31/397 , A61K31/43 , A61K31/431 , A61K31/4375 , A61K31/438 , A61K31/496 , A61K31/546 , A61K31/65 , A61K31/7052 , Y02A50/401 , Y02A50/406 , Y02A50/47 , Y02A50/471 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/483 , A61K2300/00
Abstract: Novel compositions and methods of reducing microbial resistance to antimicrobial agents and treating infections are disclosed. In particular, compositions and methods of inhibiting efflux pump activity, treating infection and methods of enhancing antimicrobial activity of antimicrobial agents are provided.
-
Patent Agency Ranking
公开(公告)号：US20090275552A1
公开(公告)日：2009-11-05
申请号：US12226525
申请日：2007-04-27
Applicant: Mahesh Vithalbhai Patel , Shrikant Vinayak Gupte , Sachin Subhash Bhagwat , Mohammad Alam Jafri , Girish Kumar Jain , Mandar Madhukar Kodgule
Inventor： Mahesh Vithalbhai Patel , Shrikant Vinayak Gupte , Sachin Subhash Bhagwat , Mohammad Alam Jafri , Girish Kumar Jain , Mandar Madhukar Kodgule
IPC: A61K31/397
CPC classification number: A61K31/43 , A61K9/0019 , A61K9/0095 , A61K9/1652 , A61K9/2054 , A61K31/546 , A61K2300/00
Abstract: The invention relates to an improved therapy for treating resistant bacterial infections caused by extended-spectrum β-lactamase (ESBLs)-producing strains in a warm-blooded animal, adjuvant step down therapy, and pharmaceutical compositions for such therapies. The invention also relates to a method for inhibiting bacterial resistance in ESBLs-producing strains so as to have better control over the therapy; achieve reduced hospital stay and adjuvant step down therapy so as to avoid recrudescence. In particular, the therapy includes antibacterial combination of cefepime with sulbactam via parenteral route, followed by oral third generation cephalosporin with a suitable β lactamase inhibitor.
Abstract translation: 本发明涉及用于治疗由温血动物中的扩展型β-内酰胺酶（ESBL））产生菌株引起的抗性细菌感染的改进疗法，佐剂降解疗法和用于此类疗法的药物组合物。 本发明还涉及一种抑制ESBLs产生菌株细菌耐药性的方法，以便更好地控制治疗; 实现减少住院时间和辅助降压治疗，避免复发。 特别地，该疗法包括通过肠胃外途径将头孢吡肟与舒巴坦的抗菌结合，随后用合适的β-内酰胺酶抑制剂口服第三代头孢菌素。
-
公开(公告)号：US10525043B2
公开(公告)日：2020-01-07
申请号：US14111627
申请日：2011-08-01
Applicant: Sachin Subhash Bhagwat , Mohammad Alam Jafri , Mahesh Vithalbhai Patel
Inventor： Sachin Subhash Bhagwat , Mohammad Alam Jafri , Mahesh Vithalbhai Patel
IPC: A61K31/431 , A61K31/546 , A61K31/43 , A61K31/407
Abstract: A pharmaceutical composition comprising antibacterial agent and tazobactam, wherein the ratio of tazobactam to the antibacterial agent in the composition is in the range of from about 0.5 to about 2 gram of tazobactam per gram of the antibacterial agent, are disclosed.
-
8.发明授权Substituted piperidino phenyloxazolidinones having antimicrobial activity with improved in vivo efficacy 有权具有抗菌活性并具有改善的体内功效的取代的哌啶子基苯基恶唑烷酮公开(公告)号：US08729269B2
公开(公告)日：2014-05-20
申请号：US12705258
申请日：2010-02-12
Applicant: Prasad Keshav Deshpande , Milind Dattatraya Sindkhedkar , Mahesh Shriram Phansalkar , Ravindra Dattatraya Yeole , Shrikant Vinayak Gupte , Yati Chugh , Nitin Shetty , Sachin Subhash Bhagwat , Milind Chintaman Shukla , Noel John De Souza , Mahesh Vithalbhai Patel
Inventor： Prasad Keshav Deshpande , Milind Dattatraya Sindkhedkar , Mahesh Shriram Phansalkar , Ravindra Dattatraya Yeole , Shrikant Vinayak Gupte , Yati Chugh , Nitin Shetty , Sachin Subhash Bhagwat , Milind Chintaman Shukla , Noel John De Souza , Mahesh Vithalbhai Patel
IPC: C07D411/06 , A61K31/454
CPC classification number: C07D491/10 , C07D413/10 , C07D413/14 , C07D495/10 , C07D497/10 , C07D513/10
Abstract: The present invention provides agents having antimicrobial activity for preventing and treating infectious diseases. Thus, the present invention provides novel substituted piperidino phenyloxazolidinone derivatives, processes for making compounds as well as antimicrobial compositions containing said derivatives as active ingredients and methods of treating bacterial infections with the said derivatives.
Abstract translation: 本发明提供具有预防和治疗感染性疾病的抗微生物活性的试剂。 因此，本发明提供新的取代的哌啶子基苯基恶唑烷酮衍生物，制备化合物的方法以及含有所述衍生物作为活性成分的抗微生物组合物以及用所述衍生物治疗细菌感染的方法。
-
9.发明申请Pharmaceutical compositions comprising sulbactam and beta-lactamase inhibitor 有权包含舒巴坦和β-内酰胺酶抑制剂的药物组合物公开(公告)号：US20140094447A1
公开(公告)日：2014-04-03
申请号：US14112156
申请日：2011-10-04
Applicant: Sachin Subhash Bhagwat , Mahesh Vithalbhai Patel
Inventor： Sachin Subhash Bhagwat , Mahesh Vithalbhai Patel
IPC: A61K31/43 , A61K31/439
CPC classification number: A61K31/439 , A61K31/4188 , A61K31/424 , A61K31/43 , A61K31/431 , A61K2300/00
Abstract: Pharmaceutical compositions and methods for treating or preventing bacterial infections are disclosed. The pharmaceutical compositions typically comprise pharmaceutically effective amount of: (a) sulbactam or a pharmaceutically acceptable salt thereof, and (b) at least one beta-lactamase inhibitor or a pharmaceutically acceptable salt thereof, with the provision that the beta-lactamase inhibitor is not sulbactam.
Abstract translation: 公开了用于治疗或预防细菌感染的药物组合物和方法。 药物组合物通常包含药学有效量的：（a）舒巴坦或其药学上可接受的盐，和（b）至少一种β-内酰胺酶抑制剂或其药学上可接受的盐，其规定：β-内酰胺酶抑制剂不是 舒巴坦
-
10.发明授权Substituted piperidino phenyloxazolidinones having antimicrobial activity with improved in vivo efficacy 失效具有抗菌活性并具有改善的体内功效的取代的哌啶子基苯基恶唑烷酮公开(公告)号：US07687627B2
公开(公告)日：2010-03-30
申请号：US10935708
申请日：2004-09-07
Applicant: Prasad Keshav Deshpande , Milind Dattatraya Sindkhedkar , Mahesh Shriram Phansalkar , Ravindra Dattatraya Yeole , Shrikant Vinayak Gupte , Yati Chugh , Nitin Shetty , Sachin Subhash Bhagwat , Milind Chintaman Shukla , Noel John De Souza , Mahesh Vithalbhai Patel
Inventor： Prasad Keshav Deshpande , Milind Dattatraya Sindkhedkar , Mahesh Shriram Phansalkar , Ravindra Dattatraya Yeole , Shrikant Vinayak Gupte , Yati Chugh , Nitin Shetty , Sachin Subhash Bhagwat , Milind Chintaman Shukla , Noel John De Souza , Mahesh Vithalbhai Patel
IPC: C07D491/113 , A61K31/438
CPC classification number: C07D491/10 , C07D413/10 , C07D413/14 , C07D495/10 , C07D497/10 , C07D513/10
Abstract: The present invention provides agents having antimicrobial activity for preventing and treating infectious diseases. Thus, the present invention provides novel substituted piperidino phenyloxazolidinone derivatives, processes for making compounds as well as antimicrobial compositions containing said derivatives as active ingredients and methods of treating bacterial infections with the said derivatives.
Abstract translation: 本发明提供具有预防和治疗感染性疾病的抗微生物活性的试剂。 因此，本发明提供新的取代的哌啶子基苯基恶唑烷酮衍生物，制备化合物的方法以及含有所述衍生物作为活性成分的抗微生物组合物以及用所述衍生物治疗细菌感染的方法。
-
-
-
-
-
-
-
-
-
Search Results
12
records
(took 0.018 seconds)
