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    PROCESS FOR THE PREPARATION OF METHIONINE
    1.
    发明申请
    PROCESS FOR THE PREPARATION OF METHIONINE 有权
    制备甲硫氨酸的方法

    公开(公告)号：US20150051421A1

    公开(公告)日：2015-02-19

    申请号：US14386165

    申请日：2013-02-26

    Applicant: Martin Koerfer ,  Hans Joachim Hasselbach ,  Stefan Reichert ,  Harald Jakob ,  Christoph Weckbecker ,  Klaus Huthmacher ,  Horst Krull ,  Bernd Drapal ,  Rainer Peter

    Inventor： Martin Koerfer ,  Hans Joachim Hasselbach ,  Stefan Reichert ,  Harald Jakob ,  Christoph Weckbecker ,  Klaus Huthmacher ,  Horst Krull ,  Bernd Drapal ,  Rainer Peter

    IPC: C07C319/12 ,  C07C323/52

    CPC classification number: C07C319/28 ,  C07C319/12 ,  C07C319/20 ,  C07C319/26 ,  C07C323/52 ,  Y02P20/142 ,  C07C323/58

    Abstract: The invention relates to a process for the preparation of D,L-methionine, in which carbon dioxide is fed to an aqueous potassium methioninate solution obtained by hydrolysis of 5-(2-methylmercaptoethyl)hydantoin, in order to precipitate out crude methionine, which is separated off and purified, where, for the purposes of purification, an aqueous solution of the separated-off crude methionine is prepared and subjected to a recrystallization, characterized in that the solution from which the recrystallization takes place contains potassium ions and also a crystallization additive, where the crystallization additive is a nonionic or anionic surfactant, or a mixture of different nonionic or anionic surfactants, and that the recrystallization takes place by introducing a 60 to 110° C.-hot methionine solution into a 35 to 80° C.-warm methionine suspension, the temperature of which is lower than that of the introduced solution, the temperature of the methionine suspension being maintained between 35 and 80° C. during the addition.

    Abstract translation: 本发明涉及一种制备D，L-甲硫氨酸的方法，其中将二氧化碳加入到通过5-（2-甲基巯基乙基）乙内酰脲的水解获得的甲硫氨酸钾水溶液中，以沉淀出粗蛋氨酸， 分离纯化，其中，为了纯化的目的，制备分离的粗制甲硫氨酸的水溶液并进行重结晶，其特征在于进行重结晶的溶液含有钾离子并且还具有结晶 添加剂，其中结晶添加剂是非离子或阴离子表面活性剂，或不同的非离子或阴离子表面活性剂的混合物，并且通过将60至110℃的热甲硫氨酸溶液引入35至80℃进行重结晶。 - 温血蛋氨酸悬浮液，其温度低于引入溶液的温度，甲硫氨酸悬浮液的温度维持在 在加入过程中在35和80℃之间。

    Filling system for an anesthetic evaporator
    6.
    发明申请
    Filling system for an anesthetic evaporator 有权
    麻醉蒸发器灌装系统

    公开(公告)号：US20060130931A1

    公开(公告)日：2006-06-22

    申请号：US11253538

    申请日：2005-10-19

    Applicant: Ahmet Turker ,  Dirk-Stefan Reichert ,  Claus Bunke

    Inventor： Ahmet Turker ,  Dirk-Stefan Reichert ,  Claus Bunke

    IPC: B65B1/04

    CPC classification number: A61M16/183 ,  A61M2205/6045

    Abstract: A filling system for an anesthetic evaporator is improved such that an anesthetic-specifically coded adapter neck (5) of a bottle adapter (1) can be introduced into the filler neck of a filling device. An outer polygon (7) is provided on the bottle adapter and an inner polygon designed correspondingly thereto is provided on the filler neck as anesthetic-specific codings.

    Abstract translation: 麻醉蒸发器的填充系统得到改进，使得适配器（1）的麻醉专用编码的适配器颈部（5）可以被引入填充装置的填充颈部。 一个外部多边形（7）设置在瓶子适配器上，并且相应地设计的内部多边形设置在填充物颈部上作为麻醉剂特异性编码。

    Filling system for an anesthetic evaporator
    7.
    发明申请
    Filling system for an anesthetic evaporator 有权
    麻醉蒸发器灌装系统

    公开(公告)号：US20060130930A1

    公开(公告)日：2006-06-22

    申请号：US11253540

    申请日：2005-10-19

    Applicant: Ahmet Turker ,  Dirk-Stefan Reichert ,  Claus Bunke

    Inventor： Ahmet Turker ,  Dirk-Stefan Reichert ,  Claus Bunke

    IPC: B65B1/04

    CPC classification number: A61M16/183

    Abstract: The interaction between a filling valve (28) on the filling device and an adapter valve on a bottle adapter has improved anesthetics filling features including radially inwardly directed bars (26), which engage (pass into) corresponding slots on the outlet pipe of the bottle adapter. The bars engaged in the slots actuate the adapter valve. The bars are provided on the inner wall of a filler neck (22).

    Abstract translation: 填充装置上的填充阀（28）和瓶适配器上的适配器阀之间的相互作用改善了麻醉剂填充特征，包括径向向内指向的杆（26），其接合（进入）瓶的出口管上的相应狭槽 适配器。 接合在槽中的杆致动适配器阀。 杆设置在加注口（22）的内壁上。

    Safety filling device for anesthetic evaporators
    9.
    发明授权
    Safety filling device for anesthetic evaporators 失效
    麻醉蒸发器安全灌装装置

    公开(公告)号：US5839487A

    公开(公告)日：1998-11-24

    申请号：US734829

    申请日：1996-10-22

    Applicant: Stefan Moll ,  Uwe Bausch ,  Stefan Linke ,  Dirk-Stefan Reichert ,  Karl-Ludwig Gippert ,  Wolfgang Falb

    Inventor： Stefan Moll ,  Uwe Bausch ,  Stefan Linke ,  Dirk-Stefan Reichert ,  Karl-Ludwig Gippert ,  Wolfgang Falb

    IPC: A61M16/18

    CPC classification number: A61M16/183

    Abstract: A safety filling device for filling a liquid anesthetic into a reservoir of an anesthetic-metering device with a receiving device, which has an inlet opening for a coupling piece or a closing piece. An essentially rigid guide lever is provided in the connection area between the receiving device and the closing piece. A hinge connection is provided which makes possible an axial displaceability of the guide lever within the inlet opening and a rotary movement of the guide lever outside the inlet opening.

    Abstract translation: 一种用于将液体麻醉剂填充到具有接收装置的麻醉计量装置的容器中的安全填充装置，所述接收装置具有用于联接件或封闭件的入口。 在接收装置和封闭件之间的连接区域中设置有基本刚性的导向杆。 提供了一种铰链连接件，其使引导杆在入口开口内的轴向移动能力和引导杆在入口开口外部的旋转运动成为可能。

    Anesthetic evaporator with intermediate container
    10.
    发明授权
    Anesthetic evaporator with intermediate container 失效
    麻醉蒸发器与中间容器

    公开(公告)号：US5490500A

    公开(公告)日：1996-02-13

    申请号：US255653

    申请日：1994-06-08

    Applicant: Dirk-Stefan Reichert ,  Gunther Hahmann ,  Wolfgang Falb

    Inventor： Dirk-Stefan Reichert ,  Gunther Hahmann ,  Wolfgang Falb

    IPC: A61M16/18 ,  A61M16/00

    CPC classification number: A61M16/18

    Abstract: An anesthetic evaporator according to the bypass principle, in which a carrier gas system is partially led through an evaporation chamber, is enriched with an anesthetic vapor to saturation there, and is again fed into the bypass flow. The function of the elements that influence the metering are not impaired by the penetration of anesthetic in an unintentional position other than the position intended for operation, and that the anesthetic located in the mixed gas outlet is not influenced by anesthetic located outside the evaporation chamber. Either the evaporation chamber line leading to the evaporation chamber or the return line leading from the evaporation chamber to the flow regulating valve opens into an intermediate container, from which a channel communicates with the interior of the evaporation chamber. Anesthetic once penetrated into the intermediate container cannot accumulate even when the anesthetic evaporator is repeatedly placed into an unintended position, but an amount which does not impair the function of the anesthetic evaporator will remain in it [the intermediate container], or it evaporates during the operation, or it can again be emptied into the evaporation chamber in a simple manner.

    Abstract translation: 根据旁路原理的麻醉蒸发器，其中载气系统部分地通过蒸发室，其富含麻醉蒸气以在那里饱和，并再次进入旁路流。 影响计量的元件的功能不会因麻醉剂渗透到除了用于操作的位置之外的非故意位置而受到影响，并且位于混合气体出口中的麻醉剂不受位于蒸发室外部的麻醉剂的影响。 通向蒸发室或从蒸发室通向流量调节阀的蒸发室管线通向中间容器，通道与蒸发室的内部连通。 即使当麻醉蒸发器重复放置在非预期位置时，一旦渗透到中间容器中的麻醉剂也不能积聚，但是不损害麻醉蒸发器功能的量将保留在其中[中间容器]，或者在 或者可以以简单的方式再次排入蒸发室。

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