公开(公告)号：US20150315108A1

公开(公告)日：2015-11-05

申请号：US14269251

申请日：2014-05-05

Applicant: SUDIP MUKHOPADHYAY ,  Hsueh S. Tung ,  Michael Van der Puy ,  Daniel C. Merkel ,  Jing Ji Ma ,  Cheryl L. Bortz ,  Barbara A. Light ,  Steven D. Phillips ,  Rajesh K. Dubey

Inventor： SUDIP MUKHOPADHYAY ,  Hsueh S. Tung ,  Michael Van der Puy ,  Daniel C. Merkel ,  Jing Ji Ma ,  Cheryl L. Bortz ,  Barbara A. Light ,  Steven D. Phillips ,  Rajesh K. Dubey

IPC: C07C17/20

CPC classification number: C07C17/25 ,  C07C17/00 ,  C07C17/04 ,  C07C17/087 ,  C07C17/10 ,  C07C17/20 ,  C07C17/204 ,  C07C17/206 ,  C07C17/21 ,  C07C17/26 ,  C07C17/269 ,  C07C17/272 ,  C07C17/278 ,  C07C21/18 ,  C07C19/01 ,  C07C19/10 ,  C07C19/08 ,  C07C21/073 ,  C07C21/04

Abstract: Disclosed are processes for the production of fluorinated olefins, preferably adapted to commercialization of CF3CF═CH2 (1234yf). Three steps may be used in preferred embodiments in which a feedstock such as CCl2═CClCH2Cl (which may be purchased or synthesized from 1,2,3-trichloropropane) is fluorinated (preferably with HF in gas-phase in the presence of a catalyst) to synthesize a compound such as CF3CCl═CH2, preferably in a 80-96% selectivity. The CF3CCl═CH2 is preferably converted to CF3CFClCH3 (244-isomer) using a SbCl5 as the catalyst which is then transformed selectively to 1234yf, preferably in a gas-phase catalytic reaction using activated carbon as the catalyst. For the first step, a mixture of Cr2O3 and FeCl3/C is preferably used as the catalyst to achieve high selectivity to CF3CCl═CH2 (96%). In the second step, SbCl5/C is preferably used as the selective catalyst for transforming 1233xf to 244-isomer, CF3CFClCH3. The intermediates are preferably isolated and purified by distillation and used in the next step without further purification, preferably to a purity level of greater than about 95%.

Abstract translation: 公开了用于生产氟化烯烃的方法，优选适于CF 3CF≡CH2（1234yf）的商业化。 在优选实施方案中可以使用三个步骤，其中诸如CCl 2 = CClCH 2 Cl（其可以由1,2,3-三氯丙烷购买或合成）的原料被氟化（优选在气相存在下，在HF的存在下） 合成化合物如CF 3 CCl = CH 2，优选选择性为80-96％。 CF 3 CCl = CH 2优选使用SbCl 5作为催化剂转化为CF 3 CFClCH 3（244-异构体），然后将其选择性地转化为1234yf，优选在使用活性炭作为催化剂的气相催化反应中。 对于第一步，优选使用Cr 2 O 3和FeCl 3 / C的混合物作为催化剂，以实现对CF 3 CCl = CH 2（96％）的高选择性。 在第二步中，SbCl 5 / C优选用作用于将1233xf转化为244-异构体CF 3 CFClCH 3的选择性催化剂。 中间体优选通过蒸馏分离和纯化，并用于下一步骤而不进一步纯化，优选纯度高于约95％。

公开(公告)号：US20120203036A9

公开(公告)日：2012-08-09

申请号：US12265335

申请日：2008-11-05

Applicant: Sudip Mukhopadhyay ,  Barbara A. Light ,  Kim M. Fleming ,  Steven D. Phillips ,  Rajesh K. Dubey

Inventor： Sudip Mukhopadhyay ,  Barbara A. Light ,  Kim M. Fleming ,  Steven D. Phillips ,  Rajesh K. Dubey

IPC: C07C21/18

CPC classification number: C07C21/18 ,  C07C17/087 ,  C07C17/25 ,  C07C19/10 ,  C07C19/08

Abstract: A multi-step process for preparing 2,3,3,3-tetrafluoro-1-propene comprising the steps of (a) contacting a starting material comprising 2-chloro-3,3,3-trifluoro-1-propene with hydrogen fluoride in the presence of activated first catalyst selected from the group consisting of antimony-halides, iron-halides, titanium halides, and tin-halides, to produce an intermediate composition; and (b) contacting said intermediate composition with a second catalyst of activated carbon to produce a final product comprising 2,3,3,3-tetrafluoro-1-propene.

Abstract translation: 一种用于制备2,3,3,3-四氟-1-丙烯的多步骤方法，包括以下步骤：（a）使包含2-氯-3,3,3-三氟-1-丙烯的原料与氟化氢 在选自锑 - 卤化物，卤化铁，卤化钛和锡 - 卤化物的活化的第一催化剂的存在下，制备中间体组合物; 和（b）使所述中间体组合物与活性炭的第二催化剂接触以产生包含2,3,3,3-四氟-1-丙烯的最终产物。

公开(公告)号：US4870157A

公开(公告)日：1989-09-26

申请号：US753093

申请日：1985-07-09

Applicant: Steven D. Phillips ,  Bonnie B. Sandel

Inventor： Steven D. Phillips ,  Bonnie B. Sandel

IPC: C07H13/04 ,  C07H13/08 ,  C07H15/04 ,  C08K5/151

CPC classification number: C07H13/04 ,  C07H13/08 ,  C07H15/04 ,  C08K5/151

Abstract: Disclosed are selected 4-acyl-2,6-dialkylphenyl adducts of mono- and polysaccharides, which are useful an antioxidants in organic materials (e.g. polyolefins) normally subject to oxidative degradation.

Abstract translation: 公开了单糖和多糖的4-酰基-2,6-二烷基苯基加合物，其可用于通常经历氧化降解的有机材料（例如聚烯烃）中的抗氧化剂。

公开(公告)号：US4616927A

公开(公告)日：1986-10-14

申请号：US671181

申请日：1984-11-15

Applicant: Steven D. Phillips ,  Jeffrey M. Reece ,  Philip J. Wyatt

Inventor： Steven D. Phillips ,  Jeffrey M. Reece ,  Philip J. Wyatt

IPC: G01N15/06 ,  G01N15/14 ,  G01N21/01 ,  G01N21/03 ,  G01N21/05 ,  G01N21/51 ,  G01N21/53 ,  G01N30/74 ,  G01N21/00

CPC classification number: G01N21/03 ,  G01N21/51 ,  G01N2021/4711 ,  G01N2021/513

Abstract: A sample cell is described that permits the measurement of the light scattering properties of very small liquid-borne samples with negligible background interference form the illumination source. A technique is described whereby the cell construction permits the measurement of the illumination intensity at the scattering sample itself, permitting, thereby, the normalization of each detected scattered signal. The cell structure and detection method incorporated therein also permit measurement of extremely small angle scattered intensities without interference of the incident light beam itself.

Abstract translation: 描述了一种样品池，其允许测量非常小的液体样品的光散射性质，其具有从照明源可忽略的背景干扰。 描述了一种技术，其中单元结构允许测量散射样本本身的照明强度，从而允许每个检测到的散射信号的归一化。 其中结合的电池结构和检测方法还允许测量非常小的角度散射强度，而不会影响入射光束本身。

公开(公告)号：US09035111B2

公开(公告)日：2015-05-19

申请号：US12196207

申请日：2008-08-21

Applicant: Sudip Mukhopadhyay ,  Cheryl L. Bortz ,  Kim M. Fleming ,  Steven D. Phillips ,  Rajesh K. Dubey

Inventor： Sudip Mukhopadhyay ,  Cheryl L. Bortz ,  Kim M. Fleming ,  Steven D. Phillips ,  Rajesh K. Dubey

IPC: C07C21/18 ,  C07C17/38 ,  C07C17/04 ,  C07C17/20 ,  C07C17/21 ,  C07C17/25

CPC classification number: C07C17/38 ,  C07C17/04 ,  C07C17/206 ,  C07C17/21 ,  C07C17/25 ,  C07C17/389 ,  C07C21/18 ,  C07C19/10 ,  C07C19/08

Abstract: A method for producing fluorinated organic compounds, including hydrofluoropropenes, which preferably comprises converting at least one compound of formula (I): CF3(—CX2X2)nCX1═H2  (I) to at least one compound of formula (II): CF3(CX2X2)nCX1═H2  (II), where X1 is Cl, Br or I, each X2 is independently selected from the group consisting of H, Cl, F, Br or J, and n is 0, 1, or 2.

Abstract translation: 包括氢氟丙烯的氟化有机化合物的制备方法，其优选包括将至少一种式（I）化合物：CF 3（-CX 2 X 2）n C X 1 = H 2（I）转化为至少一种式（II）的化合物：CF 3（CX 2 X 2 ）nCX1 = H 2（II），其中X 1为Cl，Br或I，每个X 2独立地选自H，Cl，F，Br或J，且n为0,1或2。

公开(公告)号：US20090203945A1

公开(公告)日：2009-08-13

申请号：US12196207

申请日：2008-08-21

Applicant: Sudip Mukhopadhyay ,  Cheryl L. Bortz ,  Kim M. Fleming ,  Steven D. Phillips ,  Rajesh K. Dubey

Inventor： Sudip Mukhopadhyay ,  Cheryl L. Bortz ,  Kim M. Fleming ,  Steven D. Phillips ,  Rajesh K. Dubey

IPC: C07C21/18

CPC classification number: C07C17/38 ,  C07C17/04 ,  C07C17/206 ,  C07C17/21 ,  C07C17/25 ,  C07C17/389 ,  C07C21/18 ,  C07C19/10 ,  C07C19/08

Abstract: A method for producing fluorinated organic compounds, including hydrofluoropropenes, which preferably comprises converting at least one compound of formula (I): CF3(—CX2X2)nCX1═H2  (I) to at least one compound of formula (II): CF3(CX2X2)nCX1═H2  (II), where X1 is Cl, Br or I, each X2 is independently selected from the group consisting of H, Cl, F, Br or J, and n is 0, 1, or 2.

Abstract translation: 包括氢氟丙烯的氟化有机化合物的制备方法，其优选包括转化至少一种式（I）化合物：<？在线式描述=“在线式”末端=“铅”→CF 3（ - CX2X2）nCX1-H2（I）<β-in-line-formula description =“In-line Formulas”end =“tail”？>至少一种式（II）化合物：<？in-line-formula description = “直线公式”end =“lead”？> CF3（CX2X2）nCX1-H2（II），<？in-line-formula description =“In-line Formulas”end =“tail”？>其中X1为Cl ，Br或I，每个X 2独立地选自H，Cl，F，Br或J，且n为0,1或2。

公开(公告)号：US20090124837A1

公开(公告)日：2009-05-14

申请号：US12265335

申请日：2008-11-05

Applicant: Sudip Mukhopadhyay ,  Barbara A. Light ,  Kim M. Fleming ,  Steven D. Phillips ,  Rajesh K. Dubey

Inventor： Sudip Mukhopadhyay ,  Barbara A. Light ,  Kim M. Fleming ,  Steven D. Phillips ,  Rajesh K. Dubey

IPC: C07C21/18

CPC classification number: C07C21/18 ,  C07C17/087 ,  C07C17/25 ,  C07C19/10 ,  C07C19/08

Abstract: A multi-step process for preparing 2,3,3,3-tetrafluoro-1-propene comprising the steps of (a) contacting a starting material comprising 2-chloro-3,3,3-trifluoro-1-propene with hydrogen fluoride in the presence of activated first catalyst selected from the group consisting of antimony-halides, iron-halides, titanium halides, and tin-halides, to produce an intermediate composition; and (b) contacting said intermediate composition with a second catalyst of activated carbon to produce a final product comprising 2,3,3,3-tetrafluoro-1-propene.

Abstract translation: 一种用于制备2,3,3,3-四氟-1-丙烯的多步骤方法，包括以下步骤：（a）使包含2-氯-3,3,3-三氟-1-丙烯的原料与氟化氢 在选自锑 - 卤化物，卤化铁，卤化钛和锡 - 卤化物的活化的第一催化剂的存在下，制备中间体组合物; 和（b）使所述中间体组合物与活性炭的第二催化剂接触以产生包含2,3,3,3-四氟-1-丙烯的最终产物。

公开(公告)号：US5508356A

公开(公告)日：1996-04-16

申请号：US261837

申请日：1994-06-17

Applicant: James L. Dever ,  Mannat C. Menon ,  Steven D. Phillips ,  Larry J. Baldwin

Inventor： James L. Dever ,  Mannat C. Menon ,  Steven D. Phillips ,  Larry J. Baldwin

IPC: C08F8/32 ,  C07C209/06

CPC classification number: C08F8/32 ,  Y10S210/903 ,  Y10S210/908

Abstract: A process for preparing a polybutene amine composition comprises the steps of reacting a chlorinated polybutene with an excess of at least one mole of at least one type of an amine compound per mole of the chlorinated polybutene at a reaction temperature of at least about 100.degree. C.; neutralizing the reaction mixture with a base selected from the group of alkali metal and alkaline earth metal alkoxides and amides with formulation of one of an alcohol or ammonia, respectively; neutralizing any excess base with an acid that will produce essentially no water as a by-product; and recovering the polybutene amine composition, the process including the steps of removing the alcohol or ammonia in a timely fashion; and removing excess of the amine compound.

Abstract translation: 制备聚丁烯胺组合物的方法包括以下步骤：在至少约100℃的反应温度下使氯化聚丁烯与过量的至少一种至少一种类型的胺化合物/摩尔氯代聚丁烯反应 。 用选自碱金属和碱土金属醇盐和酰胺的碱分别与醇或氨之一配制来中和反应混合物; 用基本上不产生水作为副产物的酸中和任何多余的碱; 并回收聚丁烯胺组合物，该方法包括以及时方式去除醇或氨的步骤; 并除去过量的胺化合物。

公开(公告)号：US5346965A

公开(公告)日：1994-09-13

申请号：US109226

申请日：1993-08-19

Applicant: James L. Dever ,  Mannat C. Menon ,  Steven D. Phillips ,  Larry J. Baldwin

Inventor： James L. Dever ,  Mannat C. Menon ,  Steven D. Phillips ,  Larry J. Baldwin

IPC: C08F8/32

CPC classification number: C08F8/32 ,  Y10S210/903 ,  Y10S210/908

Abstract: A process for preparing a polybutene amine composition comprises the steps of reacting a chlorinated polybutene with an excess of at least one mole of at least one type of an amine compound per mole of the chlorinated polybutene at a reaction temperature of at least about 100.degree. C.; neutralizing the reaction mixture with a base selected from the group of alkali metal and alkaline earth metal alkoxides and amides with formation of one of an alcohol or ammonia, respectively; neutralizing any excess base with an acid that will produce essentially no water as a by-product; and recovering the polybutene amine composition, the process including the steps of removing the alcohol or ammonia in a timely fashion; and removing excess of the amine compound.

Abstract translation: 制备聚丁烯胺组合物的方法包括以下步骤：在至少约100℃的反应温度下使氯化聚丁烯与过量的至少一种至少一种类型的胺化合物/摩尔氯代聚丁烯反应 。 用选自碱金属和碱土金属醇盐和酰胺的碱分别与醇或氨形成一种中和反应混合物; 用基本上不产生水作为副产物的酸中和任何多余的碱; 并回收聚丁烯胺组合物，该方法包括以及时方式去除醇或氨的步骤; 并除去过量的胺化合物。

公开(公告)号：US09102579B2

公开(公告)日：2015-08-11

申请号：US11619589

申请日：2007-01-03

Applicant: Barbara A. Light ,  Steven D. Phillips ,  Kim M. Fleming ,  Susan A. Ferguson ,  Jing Ji Ma ,  Cheryl L. Bortz ,  Michael Van Der Puy ,  Daniel C. Merkel ,  Hsueh S. Tung ,  Sudip Mukhopadhyay

Inventor： Barbara A. Light ,  Steven D. Phillips ,  Kim M. Fleming ,  Susan A. Ferguson ,  Jing Ji Ma ,  Cheryl L. Bortz ,  Michael Van Der Puy ,  Daniel C. Merkel ,  Hsueh S. Tung ,  Sudip Mukhopadhyay

IPC: C07C17/00 ,  C07C19/08 ,  C07C21/18 ,  C07C23/00 ,  C07C25/13 ,  C07C17/21 ,  C07C17/087 ,  C07C17/10 ,  C07C17/20 ,  C07C17/25

CPC classification number: C07C17/23 ,  C07C17/087 ,  C07C17/10 ,  C07C17/206 ,  C07C17/21 ,  C07C17/25 ,  C07C19/08 ,  C07C19/10 ,  C07C21/18

Abstract: Disclosed is a process for producing fluorinated organic compounds, including hydrofluoropropenes, which preferably comprises converting at least one compound of Formula (I): C(X)3CF2C(X)3  (I) to at least one compound of Formula (II) CF3CF═CHZ  (II) where each X and Z is independently H, F, Cl, I or Br, said process preferably not including any substantial amount of oxygen-containing catalyst in certain embodiments. Preferably Z is H.

Abstract translation: 公开了一种制备氟化有机化合物的方法，包括氢氟丙烯，其优选包括将至少一种式（I）化合物：C（X）3CF 2 C（X）3（I）转化为至少一种式（II）化合物CF 3 CF ≡CHZ（II）其中每个X和Z独立地为H，F，Cl，I或Br，在某些实施方案中，所述方法优选不包括任何显着量的含氧催化剂。 Z优选为