公开(公告)号：US08801966B2

公开(公告)日：2014-08-12

申请号：US12866295

申请日：2009-02-05

申请人： Xinhua Chen ,  R. Amaranatha Reddy

发明人： Xinhua Chen ,  R. Amaranatha Reddy

IPC分类号： C09K19/30 ,  C09K19/52 ,  C09K19/06 ,  C09K19/34 ,  C09K19/32 ,  C09K19/00 ,  C07C17/00 ,  C07C19/00 ,  C07C21/00 ,  C07C23/00 ,  C07C22/00

CPC分类号： C09K19/322 ,  C07C25/22 ,  C07C2601/08 ,  C09K19/30 ,  C09K19/3405 ,  C09K2019/3408 ,  Y10T428/10

摘要： Provided are liquid crystal compounds and mixtures incorporating the same. The liquid crystal compounds of the invention generally comprise a cyclopentane group and at least two other rings. In one embodiment, the liquid crystal compounds of the invention comprise a cyclopentane group and at least two other rings, one of which is a fused ring system.

摘要翻译： 提供了液晶化合物和包含它们的混合物。 本发明的液晶化合物通常包含环戊烷基团和至少两个其它环。 在一个实施方案中，本发明的液晶化合物包含环戊烷基团和至少两个其它环，其中之一是稠环体系。

公开(公告)号：US08383867B2

公开(公告)日：2013-02-26

申请号：US11592476

申请日：2006-11-03

申请人： Sudip Mukhopadhyay ,  Haridasan K. Nair ,  Rajesh K. Dubey ,  Rajiv R. Singh ,  George A. Shia

发明人： Sudip Mukhopadhyay ,  Haridasan K. Nair ,  Rajesh K. Dubey ,  Rajiv R. Singh ,  George A. Shia

IPC分类号： C07C17/25 ,  C07C19/08 ,  C07C21/18 ,  C07C17/00 ,  C07C23/00 ,  C07C25/13 ,  C07C22/00

CPC分类号： C07C17/278 ,  C07C17/23 ,  C07C17/25 ,  C07C21/18 ,  C07C19/10

摘要： Disclosed is a method for producing fluorinated organic compounds, including hydrofluoropropenes, which preferably comprises converting at least one compound of formula (I): CF3CFnCHmXa-m  (I) to at least one compound of formula (II) CF3CZCHZ  (II). where each X is independently Cl, F, I or Br; each Z is independently H or F; n is 1 or 2; m is 1, 2 or 3, provided that when n is 1, m is 1 or 2; a is 2 or 3, and a-m≧0. Certain embodiments include the step of reacting fluorinated C2 olefin, such as tetrafluoroethylene, with a Cl addition agent under conditions effective to produce a compound of formula (I).

摘要翻译： 公开了一种制备氟化有机化合物的方法，包括氢氟丙烯，其优选包括将至少一种式（I）化合物：CF 3 CF n CH m X a-m（I）转化为至少一种式（II）CF 3 CZCHZ（II）化合物。 其中每个X独立地为Cl，F，I或Br; 每个Z独立地为H或F; n为1或2; m为1,2或3，条件是当n为1时，m为1或2; a为2或3，a-m≥0。 某些实施方案包括在有效产生式（I）化合物的条件下，将氟化C 2烯烃如四氟乙烯与Cl加成剂反应的步骤。

公开(公告)号：US08084653B2

公开(公告)日：2011-12-27

申请号：US11619592

申请日：2007-01-03

申请人： Hsueh S. Tung ,  Sudip Mukhopadhyay ,  Michael Van Der Puy ,  Daniel C. Merkel ,  Jing Ji Ma ,  Cheryl L. Bortz ,  Barbara A. Light ,  Steven D. Phillips ,  Rajesh K. Dubey

发明人： Hsueh S. Tung ,  Sudip Mukhopadhyay ,  Michael Van Der Puy ,  Daniel C. Merkel ,  Jing Ji Ma ,  Cheryl L. Bortz ,  Barbara A. Light ,  Steven D. Phillips ,  Rajesh K. Dubey

IPC分类号： C07C17/00 ,  C07C19/08 ,  C07C21/18 ,  C07C23/00 ,  C07C25/13

CPC分类号： C07C17/25 ,  C07C17/00 ,  C07C17/04 ,  C07C17/087 ,  C07C17/10 ,  C07C17/20 ,  C07C17/204 ,  C07C17/206 ,  C07C17/21 ,  C07C17/26 ,  C07C17/269 ,  C07C17/272 ,  C07C17/278 ,  C07C21/18 ,  C07C19/01 ,  C07C19/10 ,  C07C19/08 ,  C07C21/073 ,  C07C21/04

摘要： Disclosed are processes for the production of fluorinated olefins, preferably adapted to commercialization of CF3CF═CH2 (1234yf). Three steps may be used in preferred embodiments in which a feedstock such as CCl2═CClCH2Cl (which may be purchased or synthesized from 1,2,3-trichloropropane) is fluorinated (preferably with HF in gas-phase in the presence of a catalyst) to synthesize a compound such as CF3CCl═CH2, preferably in a 80-96% selectivity. The CF3CCl═CH2 is preferably converted to CF3CFClCH3 (244-isomer) using a SbCl5 as the catalyst which is then transformed selectively to 1234yf, preferably in a gas-phase catalytic reaction using activated carbon as the catalyst. For the first step, a mixture of Cr2O3 and FeCl3/C is preferably used as the catalyst to achieve high selectivity to CF3CCl═CH2 (96%). In the second step, SbCl5/C is preferably used as the selective catalyst for transforming 1233xf to 244-isomer, CF3CFClCH3. The intermediates are preferably isolated and purified by distillation and used in the next step without further purification, preferably to a purity level of greater than about 95%.

摘要翻译： 公开了用于生产氟化烯烃的方法，优选适于CF 3CF≡CH2（1234yf）的商业化。 在优选实施方案中可以使用三个步骤，其中诸如CCl 2 = CClCH 2 Cl（其可以从1,2,3-三氯丙烷购买或合成）的原料被氟化（优选在气相存在下在HF的情况下为催化剂） 合成化合物如CF 3 CCl = CH 2，优选选择性为80-96％。 CF 3 CCl = CH 2优选使用SbCl 5作为催化剂转化为CF 3 CFClCH 3（244-异构体），然后将其选择性地转化为1234yf，优选在使用活性炭作为催化剂的气相催化反应中。 对于第一步，优选使用Cr 2 O 3和FeCl 3 / C的混合物作为催化剂以实现对CF 3 CCl = CH 2（96％）的高选择性。 在第二步中，SbCl 5 / C优选用作用于将1233xf转化为244-异构体CF 3 CFClCH 3的选择性催化剂。 中间体优选通过蒸馏分离和纯化，并用于下一步骤而不进一步纯化，优选纯度高于约95％。

公开(公告)号：US08044243B2

公开(公告)日：2011-10-25

申请号：US12279247

申请日：2007-02-09

申请人： Shalini Sharma ,  Reid W. von Borstel

发明人： Shalini Sharma ,  Reid W. von Borstel

IPC分类号： C07C211/00 ,  C07C21/18 ,  C07C17/00 ,  C07C19/08 ,  C07C22/00 ,  C07C25/13 ,  C07C19/00 ,  C07C21/00 ,  C07C23/00 ,  C07C25/00

CPC分类号： C07C43/23

摘要： Agents useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, polycystic ovary syndrome, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis are disclosed. Formula (I) wherein n is 1 or 2; q is 0 or 1; t is 0 or 1; R1 is alkyl having from 1 to 3 carbon atoms; R2 is hydrogen, halo, alkyl having from 1 to 3 carbon atoms, or alkoxy having from 1 to 3 carbon atoms; A is unsubstituted or substituted phenyl; or cycloalkyl; or a 5 or 6 membered heteroaromatic ring. Alternatively, the agent can be a pharmaceutically acceptable salt of the compound of Formula I.

摘要翻译： 公开了可用于治疗各种代谢紊乱（例如胰岛素抵抗综合征，糖尿病，多囊卵巢综合征，高脂血症，脂肪肝疾病，恶病质，肥胖症，动脉粥样硬化和动脉硬化）的药剂。 式（I）其中n为1或2; q为0或1; t为0或1; R1是具有1至3个碳原子的烷基; R2是氢，卤素，具有1至3个碳原子的烷基或具有1至3个碳原子的烷氧基; A是未取代或取代的苯基; 或环烷基; 或5或6元杂芳族环。 或者，该试剂可以是式I化合物的药学上可接受的盐。

公开(公告)号：US08030531B2

公开(公告)日：2011-10-04

申请号：US12335598

申请日：2008-12-16

申请人： Terry Wayne Redwine

发明人： Terry Wayne Redwine

IPC分类号： C07C23/00

CPC分类号： C07C21/20 ,  C07C17/25 ,  C07C17/395

摘要： 2,3-dichlorobutadiene-1,3 of high purity is produced from 1,2,3,4-tetrachlorobutane by a process comprising the steps of dehydrochlorination, chlorination of the reaction product obtained in the dehydrochlorination step and subsequent separation of a 2,3-dichlorobutadiene-1,3 composition from the reaction product of the chlorination step.

摘要翻译： 通过包括以下步骤的方法由1,2,3,4-四氯丁烷生产高纯度的2,3-二氯丁二烯-1,3-，其中：脱氯化氢，氯化脱氯化氢步骤中得到的反应产物，随后分离出2， 氯化步骤的反应产物的3-二氯丁二烯-1,3-组合物。

公开(公告)号：US07972525B2

公开(公告)日：2011-07-05

申请号：US12598038

申请日：2008-06-12

申请人： Mark L. Robin

发明人： Mark L. Robin

IPC分类号： A62D1/00 ,  C09K5/00 ,  C09K5/04 ,  C09K3/00 ,  B01F1/00 ,  C23G5/00 ,  H01B3/24 ,  C11D17/00 ,  C11D17/08 ,  C07C17/00 ,  C07C19/08 ,  C07C21/18 ,  C07C23/00 ,  C07C25/13

CPC分类号： C09K5/045 ,  A62D1/0057 ,  A62D1/0092 ,  C08J9/146 ,  C08J9/149 ,  C08J2203/02 ,  C08J2203/14 ,  C08J2207/04 ,  C09K3/30 ,  C09K2205/126 ,  C11D7/505 ,  C11D7/5054 ,  C11D7/5072 ,  C11D7/5086

摘要： Azeotropic or azeotrope-like compositions are disclosed. The azeotropic or azeotrope-like compositions are mixtures of E-1,1,1,4,4,4-hexafluoro-2-butene with methyl formate, n-pentane, 2-methylbutane, trans-1,2-dichloroethylene, 1,1,1,3,3-pentafluoropropane, n-butane or isobutane. Also disclosed is a process of preparing a thermoplastic or thermoset foam by using such azeotropic or azeotrope-like compositions as blowing agents. Also disclosed is a process of producing refrigeration by using such azeotropic or azeotrope-like compositions. Also disclosed is a process of using such azeotropic or azeotrope-like compositions as solvents. Also disclosed is a process of producing an aerosol product by using such azeotropic or azeotrope-like compositions. Also disclosed is a process of using such azeotropic or azeotrope-like compositions as heat transfer media. Also disclosed is a process of extinguishing or suppressing a fire by using such azeotropic or azeotrope-like compositions. Also disclosed is a process of using such azeotropic or azeotrope-like compositions as dielectrics.

摘要翻译： 公开了共沸或类共沸组合物。 共沸或类共沸组合物是E-1,1,1,4,4,4-六氟-2-丁烯与甲酸甲酯，正戊烷，2-甲基丁烷，反式-1,2-二氯乙烯，1 ，1,1,3,3-五氟丙烷，正丁烷或异丁烷。 还公开了通过使用这种共沸或类共沸组合物作为发泡剂制备热塑性或热固性泡沫的方法。 还公开了通过使用这种共沸或类共沸组合物生产制冷的方法。 还公开了使用这种共沸或类共沸组合物作为溶剂的方法。 还公开了通过使用这种共沸或类共沸组合物生产气溶胶产品的方法。 还公开了使用这种共沸或类共沸组合物作为传热介质的方法。 还公开了通过使用这种共沸或类共沸组合物扑灭或抑制火的过程。 还公开了使用这种共沸或类共沸组合物作为电介质的方法。

公开(公告)号：US07972524B2

公开(公告)日：2011-07-05

申请号：US12597499

申请日：2008-04-28

申请人： Mark L. Robin

发明人： Mark L. Robin

IPC分类号： A62D1/00 ,  C09K5/00 ,  C09K5/04 ,  C09K3/00 ,  B01F1/00 ,  C23G5/00 ,  H01B3/24 ,  C11D17/00 ,  C11D17/08 ,  C07C17/00 ,  C07C19/08 ,  C07C21/18 ,  C07C23/00 ,  C07C25/13

CPC分类号： C08J9/149 ,  A62D1/0057 ,  A62D1/0092 ,  C08J2203/12 ,  C08J2203/14 ,  C08J2203/142 ,  C08J2207/04 ,  C09K5/045 ,  C09K2205/104 ,  C09K2205/12 ,  C09K2205/122 ,  C09K2205/126 ,  C09K2205/22

摘要： Azeotropic or azeotrope-like compositions are disclosed. The azeotropic or azeotrope-like compositions are mixtures of Z-1,1,1,4,4,4-hexafluoro-2-butene with methyl formate, pentane, 2-methylbutane, 1,1,1,3,3-pentafluorobutane, trans-1,2-dichloroethylene, 1,1,1,3,3-pentafluoropropane, dimethoxymethane, or cyclopentane. Also disclosed is a process of preparing a thermoplastic or thermoset foam by using such azeotropic or azeotrope-like compositions as blowing agents. Also disclosed is a process of producing refrigeration by using such azeotropic or azeotrope-like compositions. Also disclosed is a process of using such azeotropic or azeotrope-like compositions as solvents. Also disclosed is a process of producing an aerosol product by using such azeotropic or azeotrope-like compositions. Also disclosed is a process of using such azeotropic or azeotrope-like compositions as heat transfer media. Also disclosed is a process of extinguishing or suppressing a fire by using such azeotropic or azeotrope-like compositions. Also disclosed is a process of using such azeotropic or azeotrope-like compositions as dielectrics.

摘要翻译： 公开了共沸或类共沸组合物。 共沸或类共沸组合物是Z-1,1,1,4,4,4-六氟-2-丁烯与甲酸甲酯，戊烷，2-甲基丁烷，1,1,1,3,3-五氟丁烷的混合物 ，反-1,2-二氯乙烯，1,1,1,3,3-五氟丙烷，二甲氧基甲烷或环戊烷。 还公开了通过使用这种共沸或类共沸组合物作为发泡剂制备热塑性或热固性泡沫的方法。 还公开了通过使用这种共沸或类共沸组合物生产制冷的方法。 还公开了使用这种共沸或类共沸组合物作为溶剂的方法。 还公开了通过使用这种共沸或类共沸组合物生产气溶胶产品的方法。 还公开了使用这种共沸或类共沸组合物作为传热介质的方法。 还公开了通过使用这种共沸或类共沸组合物扑灭或抑制火的过程。 还公开了使用这种共沸或类共沸组合物作为电介质的方法。

公开(公告)号：US07667083B2

公开(公告)日：2010-02-23

申请号：US12410524

申请日：2009-03-25

申请人： Isamu Kaneko ,  Atsushi Watakabe ,  Jyunichi Tayanagi ,  Susumu Saito

发明人： Isamu Kaneko ,  Atsushi Watakabe ,  Jyunichi Tayanagi ,  Susumu Saito

IPC分类号： C07C17/00 ,  C07C19/00 ,  C07C21/00 ,  C07C23/00

CPC分类号： C07C303/22 ,  C07C309/82 ,  C07C309/84 ,  C08F214/18 ,  C08J5/2237 ,  C08J2327/18 ,  H01B1/122 ,  H01M2008/1095 ,  H01M2300/0082

摘要： A compound containing two fluorosulfonyl groups which are groups convertible to sulfonic acid groups, an intermediate therefor, and methods for their production with high productivity, are provided. Also provided are a fluorosulfonyl group-containing polymer obtained by polymerizing such a compound, and a sulfonic acid group-containing polymer obtained from such a polymer.A method for producing a compound of the following formula (m0), such a compound, a fluorosulfonyl group-containing polymer obtained by polymerizing such a compound, and a sulfonic acid group-containing polymer obtained from such a polymer, provided that RF01 is a single bond or a C1-6 bivalent perfluoro organic group, RF02 is a C1-6 bivalent perfluoro organic group, and n is 0 or 1.

摘要翻译： 提供了含有可转化成磺酸基团的两个氟磺酰基的化合物，其中间体，以及高生产率的生产方法。 还提供了通过聚合这种化合物获得的含氟磺酰基的聚合物和由这种聚合物获得的含磺酸基的聚合物。 制备下式（m0）化合物的方法，该化合物，通过聚合该化合物得到的含氟磺酰基的聚合物和由这种聚合物得到的含磺酸基的聚合物，条件是RF01为 单键或C1-6二价全氟有机基团，RF02为C1-6二价全氟有机基团，n为0或1。

公开(公告)号：US07301059B2

公开(公告)日：2007-11-27

申请号：US11726449

申请日：2007-03-22

申请人： Victor Filippovich Cherstkov ,  Nina Ivanova Delyagina ,  Viacheslav A. Petrov ,  Weiming Qiu ,  Paul R. Resnick

发明人： Victor Filippovich Cherstkov ,  Nina Ivanova Delyagina ,  Viacheslav A. Petrov ,  Weiming Qiu ,  Paul R. Resnick

IPC分类号： C07C19/08 ,  C07C21/18 ,  C07C23/00

CPC分类号： C07C303/22 ,  C07C17/093 ,  C07C21/18 ,  C07C43/17 ,  C07C253/16 ,  C07C255/10 ,  C07C305/26 ,  C08F14/28 ,  C08F214/18 ,  C07C309/82

摘要： Hexafluoroisobutylene and its higher homologs are easily reacted with SO3 to give fluorosulfates of the formula CH2═C(R)CF2OSO2F, wherein R is a linear branched or cyclic fluoroalkyl group comprised of 1 to 10 carbon atoms and may contain ether oxygen. These compounds react under mild conditions with many nucleophiles to give CH2═C(R)CF2X, where X is derived from the nucleophile. This reaction provides a route to many substituted hexafluoroisobutylenes, which copolymerize easily with other fluoro- and hydrocarbon monomers such as vinylidene fluoride and ethylene.

公开(公告)号：US3766282A

公开(公告)日：1973-10-16

申请号：US3766282D

申请日：1971-04-14

申请人： DU PONT

发明人： SIEJA J

IPC分类号： C07C13/34 ,  C07C41/30 ,  C07C43/192 ,  C07C43/196 ,  C07C45/76 ,  C07C49/753 ,  C08F10/00 ,  C08F236/04 ,  C07C23/00 ,  C07C23/06

CPC分类号： C08F10/00 ,  C07C13/34 ,  C07C41/22 ,  C07C41/30 ,  C07C43/192 ,  C07C43/196 ,  C07C45/76 ,  C07C49/753 ,  C07C2601/04 ,  C07C2602/38 ,  C08F236/04

摘要： DISCLOSED HEREIN ARE BICYCLOBUTANES OF THE FORMULA

1-(R3-C(-R2)=C(-R1)-),2-R7,2-R6,4-R4,4-R5-BICYCLO(1.1.0)-

BUTANE

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