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公开(公告)号:US06297370B1
公开(公告)日:2001-10-02
申请号:US08441970
申请日:1995-05-16
申请人: Tai-An Cha , Eileen Beall , Bruce Irvine , Janice Kolberg , Michael S. Urdea
发明人: Tai-An Cha , Eileen Beall , Bruce Irvine , Janice Kolberg , Michael S. Urdea
IPC分类号: C07H2104
CPC分类号: C12Q1/707 , A61K38/09 , A61K39/00 , C07K14/005 , C12N2770/24222 , A61K2300/00
摘要: The present application features nucleic acid, peptide and antibody compositions relating to genotypes of hepatitis C virus and methods of using such compositions for diagnostic and therapeutic purposes.
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公开(公告)号:US06214583B1
公开(公告)日:2001-04-10
申请号:US08442144
申请日:1995-05-16
申请人: Tai-An Cha , Eileen Beall , Bruce Irvine , Janice Kolberg , Michael S. Urdea
发明人: Tai-An Cha , Eileen Beall , Bruce Irvine , Janice Kolberg , Michael S. Urdea
IPC分类号: C12Q170
CPC分类号: C12Q1/707 , A61K38/09 , A61K39/00 , C07K14/005 , C12N2770/24222 , A61K2300/00
摘要: The present application features nucleic acid, peptide and antibody compositions relating to genotypes of hepatitis C virus and methods of using such compositions for diagnostic and therapeutic purposes.
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公开(公告)号:US5372928A
公开(公告)日:1994-12-13
申请号:US201066
申请日:1994-02-24
申请人: Tatsuo Miyamura , Izumi Saito , Michael Houghton , Amy J. Weiner , Jang Han , Janice A. Kolberg , Tai-An Cha , Bruce D. Irvine
发明人: Tatsuo Miyamura , Izumi Saito , Michael Houghton , Amy J. Weiner , Jang Han , Janice A. Kolberg , Tai-An Cha , Bruce D. Irvine
CPC分类号: C07K14/005 , A61K39/00 , C12N2770/24222 , Y10S436/82 , Y10S530/826
摘要: Two new isolates of the Hepatitis C virus (HCV), J1 and J7, are disclosed. These new isolates comprise nucleotide and amino acid sequences which are distinct from the prototype HCV isolate, HCV1. Thus, J1 and J7 provide new polynucleotides and polypeptides for use, inter alia, in diagnostics, recombinant protein production and vaccine development.
摘要翻译: 公布了丙型肝炎病毒(HCV),J1和J7两种新的分离株。 这些新的分离物包含与原型HCV分离株HCV1不同的核苷酸和氨基酸序列。 因此,J1和J7提供了新的多核苷酸和多肽,尤其用于诊断,重组蛋白生产和疫苗开发中。
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公开(公告)号:US5721354A
公开(公告)日:1998-02-24
申请号:US414926
申请日:1995-03-31
申请人: Richard Spaete , Tai-An Cha
发明人: Richard Spaete , Tai-An Cha
IPC分类号: G01N33/569 , A61K35/76 , A61K38/00 , A61K39/00 , A61K39/245 , A61P31/12 , C07K14/045 , C07K14/405 , C12N7/02 , C12N7/04 , C12N15/09 , C12Q1/68 , C07H21/04
CPC分类号: C07K14/005 , C07K14/405 , C12N7/00 , A61K38/00 , A61K39/00 , C12N2710/16122
摘要: Provided are novel Toledo and Towne human cytomegalovirus DNA sequences (HCMV) and proteins encoded thereby. The sequences are useful in methods and compositions for detecting HCMV infections and in immunogenic compositions for preventing HCMV infections.
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公开(公告)号:US06635477B1
公开(公告)日:2003-10-21
申请号:US09892100
申请日:2001-06-26
申请人: Richard Spaete , Tai-An Cha
发明人: Richard Spaete , Tai-An Cha
IPC分类号: C12N1574
CPC分类号: C07K14/005 , A61K38/00 , A61K39/00 , C07K14/405 , C12N7/00 , C12N2710/16122
摘要: Provided are novel Toledo and Towne human cytomegalovirus DNA sequences (HCMV) and proteins encoded thereby. The sequences are useful in methods and compositions for detecting HCMV infections and in immunogenic compositions for preventing HCMV infections.
摘要翻译: 提供了新的托莱多和Towne人巨细胞病毒DNA序列(HCMV)和由此编码的蛋白质。 该序列可用于检测HCMV感染的方法和组合物以及用于预防HCMV感染的免疫原性组合物中。
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公开(公告)号:US06291236B1
公开(公告)日:2001-09-18
申请号:US09527657
申请日:2000-03-17
申请人: Richard Spaete , Tai-An Cha
发明人: Richard Spaete , Tai-An Cha
IPC分类号: C12N1500
CPC分类号: C07K14/005 , A61K38/00 , A61K39/00 , C07K14/405 , C12N7/00 , C12N2710/16122
摘要: Provided are novel Toledo and Towne Human cytomegalovirus DNA sequences (HCMV) and proteins encoded thereby. The sequences are useful in methods and compositions for detecting HCMV infections and in immunogenic compositions for preventing HCMV infections.
摘要翻译: 提供新型托莱多和Towne人巨细胞病毒DNA序列(HCMV)和由此编码的蛋白质。 该序列可用于检测HCMV感染的方法和组合物以及用于预防HCMV感染的免疫原性组合物中。
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公开(公告)号:US06190864B1
公开(公告)日:2001-02-20
申请号:US08221653
申请日:1994-04-01
申请人: Tai-An Cha , Eileen Beall , Bruce Irvine , Janice Kolberg , Michael S. Urdea
发明人: Tai-An Cha , Eileen Beall , Bruce Irvine , Janice Kolberg , Michael S. Urdea
IPC分类号: C12Q168
CPC分类号: C12Q1/707 , A61K38/09 , A61K39/00 , C07K14/005 , C12N2770/24222 , A61K2300/00
摘要: The present application features nucleic acid, peptide and antibody compositions relating to genotypes of hepatitis C virus and methods of using such compositions for diagnostic and therapeutic purposes.
摘要翻译: 本申请的特征在于与丙型肝炎病毒的基因型相关的核酸,肽和抗体组合物以及用于诊断和治疗目的的这些组合物的使用方法。
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公开(公告)号:US6040170A
公开(公告)日:2000-03-21
申请号:US253682
申请日:1999-02-18
申请人: Richard Spaete , Tai-An Cha
发明人: Richard Spaete , Tai-An Cha
IPC分类号: G01N33/569 , A61K35/76 , A61K38/00 , A61K39/00 , A61K39/245 , A61P31/12 , C07K14/045 , C07K14/405 , C12N7/02 , C12N7/04 , C12N15/09 , C12Q1/68 , C12N1/20 , C07H21/04 , C12N15/00 , C12Q1/70
CPC分类号: C07K14/005 , C07K14/405 , C12N7/00 , A61K38/00 , A61K39/00 , C12N2710/16122
摘要: Provided are novel Toledo and Towne human cytomegalovirus DNA sequences (HCMV) and proteins encoded thereby. The sequences are useful in methods and compositions for detecting HCMV infections and in immunogenic compositions for preventing HCMV infections.
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公开(公告)号:US5925751A
公开(公告)日:1999-07-20
申请号:US926922
申请日:1997-09-10
申请人: Richard Spaete , Tai-An Cha
发明人: Richard Spaete , Tai-An Cha
IPC分类号: G01N33/569 , A61K35/76 , A61K38/00 , A61K39/00 , A61K39/245 , A61P31/12 , C07K14/045 , C07K14/405 , C12N7/02 , C12N7/04 , C12N15/09 , C12Q1/68 , C07H21/04 , C12N15/00 , C12Q1/70
CPC分类号: C07K14/005 , C07K14/405 , C12N7/00 , A61K38/00 , A61K39/00 , C12N2710/16122
摘要: Provided are novel Toledo and Towne human cytomegalovirus DNA sequences (HCMV) and proteins encoded thereby. The sequences are useful in methods and compositions for detecting HCMV infections and in immunogenic compositions for preventing HCMV infections.
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公开(公告)号:US5856437A
公开(公告)日:1999-01-05
申请号:US334255
申请日:1994-11-03
申请人: Tatsuo Miyamura , Izumi Saito , Michael Houghton , Amy J. Weiner , Jang Han , Janice A. Kolberg , Tai-An Cha , Bruce D. Irvine
发明人: Tatsuo Miyamura , Izumi Saito , Michael Houghton , Amy J. Weiner , Jang Han , Janice A. Kolberg , Tai-An Cha , Bruce D. Irvine
CPC分类号: C07K14/005 , A61K39/00 , C12N2770/24222 , Y10S436/82 , Y10S530/826
摘要: Two new isolates of the Hepatitis C virus (HCV), J1 and J7, are disclosed. These new isolates comprise nucleotide and amino acid sequences which are distinct from the prototype HCV isolate, HCV1. Thus, J1 and J7 provide new polynucleotides and polypeptides for use, inter alia, in diagnostics, recombinant protein production and vaccine development.
摘要翻译: 公布了丙型肝炎病毒(HCV),J1和J7两种新的分离株。 这些新的分离物包含与原型HCV分离株HCV1不同的核苷酸和氨基酸序列。 因此,J1和J7提供了新的多核苷酸和多肽,尤其用于诊断,重组蛋白生产和疫苗开发中。
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