公开(公告)号：US20120168384A1

公开(公告)日：2012-07-05

申请号：US13418932

申请日：2012-03-13

Applicant: Takao ANZAI ,  Takako Ariga

Inventor： Takao ANZAI ,  Takako Ariga

IPC: B01D15/08 ,  C08F220/56

CPC classification number: B01J20/267 ,  A61M1/3615 ,  A61M1/3679 ,  B01J20/28004 ,  B01J20/28011 ,  B01J2220/58 ,  C08F220/56 ,  Y10T428/2982

Abstract: A drug-adsorbing material capable of efficiently adsorbing and eliminating drugs (such as carcinostatic agents) from blood with a small amount without causing foreign body recognition reaction, such as blood coagulation, and a medical device provided with said drug-adsorbing material. The drug-adsorbing material is based on polymeric microparticles which swell upon adsorption of plasma components at pH value of 7 or above and keep their shape after swelling. The drug-adsorbing material is incorporated into a drug-administrating device for drug adsorption.

Abstract translation: 能够有效地吸收和消除少量血液中的药物（如制癌剂）的药物吸附材料，而不引起诸如血液凝固的异物识别反应，以及设置有药物吸附材料的医疗装置。 药物吸附材料基于聚合物微粒，其在pH值为7或更高的等离子体组分吸附时溶胀并在溶胀后保持其形状。 将药物吸附材料并入用于药物吸附的药物给药装置中。

公开(公告)号：US08101374B2

公开(公告)日：2012-01-24

申请号：US12528112

申请日：2008-03-06

Applicant: Tetsuro Kawanishi ,  Yuzuru Saito ,  Takako Ariga

Inventor： Tetsuro Kawanishi ,  Yuzuru Saito ,  Takako Ariga

IPC: C12Q1/54 ,  C12Q1/28 ,  C12N9/02 ,  C07D231/22 ,  C07D231/24

CPC classification number: C07D231/48 ,  C07D231/46

Abstract: It is an object of the present invention to provide a means for measuring a concentration of various components rapidly with high accuracy and high sensitivity. The present invention is to provide an oxidative chromogenic compound or salt thereof represented by the following chemical formula (1): wherein R1 and R2 are each independently a linear or branched alkyl group having 1 to 5 carbon atoms; R3, R4, R5, R6 and R7 are each independently a hydrogen atom, a carboxyl group or a sulfonic acid group, or salt thereof, provided that at least one of R3 to R7 is a carboxyl group or a sulfonic acid group, or salt thereof, and the others are hydrogen atoms, and the production method thereof, and the reagent composition and test instrument using the same.

Abstract translation: 本发明的目的是提供一种用于以高精度和高灵敏度快速测量各种组分的浓度的装置。 本发明提供由以下化学式（1）表示的氧化显色化合物或其盐：其中R 1和R 2各自独立地为具有1至5个碳原子的直链或支链烷基; R 3，R 4，R 5，R 6和R 7各自独立地为氢原子，羧基或磺酸基或其盐，条件是R 3至R 7中的至少一个为羧基或磺酸基或盐 其他的是氢原子及其制备方法，以及使用其的试剂组合物和试验仪器。

公开(公告)号：US20100247667A1

公开(公告)日：2010-09-30

申请号：US12732491

申请日：2010-03-26

Applicant: Takako Ariga ,  Takao Anzai ,  Jun Konishi

Inventor： Takako Ariga ,  Takao Anzai ,  Jun Konishi

IPC: A61K9/50

CPC classification number: A61L27/50 ,  A61L27/16 ,  A61L27/52 ,  A61L2430/34 ,  C08L33/26

Abstract: A soft tissue enlarging material including fine particles of a pH-response water-absorbing swelling polymer having an average particle size of from 15 μm to 40 μm wherein swelling of said particles is completed within 10 minutes after immersion in a 10 mM phosphate buffer physiological saline solution (pH: 7) at 37° C.

Abstract translation: 一种软组织扩大材料，包括平均粒度为15μm至40μm的pH响应吸水溶胀性聚合物的细颗粒，其中所述颗粒的溶胀在浸入10mM磷酸盐缓冲液生理盐水中10分钟后完成 溶液（pH：7）在37℃

公开(公告)号：US20100062464A1

公开(公告)日：2010-03-11

申请号：US12528112

申请日：2008-03-06

Applicant: Tetsuro Kawanishi ,  Yuzuru Saito ,  Takako Ariga

Inventor： Tetsuro Kawanishi ,  Yuzuru Saito ,  Takako Ariga

IPC: C12Q1/28 ,  C12N9/04 ,  C07D231/44

CPC classification number: C07D231/48 ,  C07D231/46

Abstract: It is an object of the present invention to provide a means for measuring a concentration of various components rapidly with high accuracy and high sensitivity. The present invention is to provide an oxidative chromogenic compound or salt thereof represented by the following chemical formula (1): wherein R1 and R2 are each independently a linear or branched alkyl group having 1 to 5 carbon atoms; R3, R4, R5, R6 and R7 are each independently a hydrogen atom, a carboxyl group or a sulfonic acid group, or salt thereof, provided that at least one of R3 to R7 is a carboxyl group or a sulfonic acid group, or salt thereof, and the others are hydrogen atoms, and the production method thereof, and the reagent composition and test instrument using the same.

Abstract translation: 本发明的目的是提供一种用于以高精度和高灵敏度快速测量各种组分的浓度的装置。 本发明提供由以下化学式（1）表示的氧化显色化合物或其盐：其中R 1和R 2各自独立地为具有1至5个碳原子的直链或支链烷基; R 3，R 4，R 5，R 6和R 7各自独立地为氢原子，羧基或磺酸基或其盐，条件是R 3至R 7中的至少一个为羧基或磺酸基或盐 其他的是氢原子及其制备方法，以及使用其的试剂组合物和试验仪器。