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    Improved sensors and sensing for monitoring neuromuscular blockade
    2.
    发明申请
    Improved sensors and sensing for monitoring neuromuscular blockade 有权
    改进的传感器和传感器用于监测神经肌肉阻滞

    公开(公告)号：US20100081963A1

    公开(公告)日：2010-04-01

    申请号：US12311105

    申请日：2007-09-14

    申请人： Terence Gilhuly

    发明人： Terence Gilhuly

    IPC分类号： A61B5/05

    CPC分类号： A61B5/05 ,  A61B5/0002 ,  A61B5/01 ,  A61B5/02055 ,  A61B5/1106 ,  A61B5/4821 ,  A61B5/72 ,  A61B5/746 ,  A61M2005/14208 ,  G05B17/02 ,  G06F19/00 ,  G06F19/3456 ,  G16H50/50 ,  Y02A90/26

    摘要： Improved sensors and sensing methods for detection of Neuromuscular Blockade (NMB), for example to improve monitoring generally, as well as facilitate automated NMB drug administration. The methods, systems, devices, etc., herein can increase the quantity and quality of data available. The methods, etc., include translation between commonly available sensing types, use of partially saturated sensor measurements, use of a model of neurotransmitter storage and release and sophisticated use of more than one sensor simultaneously. These methods are aided by new sensors and methods of decreasing electrical noise. An implementation of the methods, systems, devices, etc., herein is automated drug delivery for NMB, whether through an advisor system or through with full computer control.

    摘要翻译： 改进的用于检测神经肌肉阻滞（NMB）的传感器和感测方法，例如通常改善监测，以及促进自动NMB药物给药。 这里的方法，系统，设备等可以增加可用数据的数量和质量。 方法等包括通常可用的感测类型之间的翻译，部分饱和传感器测量的使用，神经递质储存和释放的模型的使用以及同时多个传感器的复杂使用。 这些方法得到了新的传感器和降低电噪声的方法的帮助。 这里的方法，系统，设备等的实现是NMB的自动化药物递送，无论是通过顾问系统还是通过全面的计算机控制。

    BETTER BITE BLOCK
    5.
    发明申请
    BETTER BITE BLOCK 审中-公开

    公开(公告)号：US20180221611A1

    公开(公告)日：2018-08-09

    申请号：US15888073

    申请日：2018-02-04

    申请人： Terence Gilhuly

    发明人： Terence Gilhuly

    IPC分类号： A61M16/04

    CPC分类号： A61M16/0493 ,  A61M16/0688 ,  A61M16/085 ,  A61M2205/0216 ,  A61M2230/432

    摘要： Patients undergoing general anesthetics frequently experience emergence clenching where the patient may bite onto their breathing tube and may clench their teeth. These activities lead to dental damage and negative pressure pulmonary edema. The invention of this patent is a simpler, better bite block that may be used to prevent these injuries. The bite block presented comprises a deformable material used as a core around which a bite-resistant material is wrapped to prevent damage to the core by patient biting. The bite-resistant material may be formed into a distal tail that the user can pull to retain or retrieve the device. It may also have a patch of adhesive to attach the bite block to locations including the patient, the surgical drapes and the patient's breathing airway, and thereby prevent loss of the bite block.

    Pressure release means and placement indicator for inflatable catheter or respiratory gas supply retention means
    6.
    发明申请
    Pressure release means and placement indicator for inflatable catheter or respiratory gas supply retention means 审中-公开
    用于充气导管或呼吸气体供应保持装置的压力释放装置和放置指示器

    公开(公告)号：US20140196721A1

    公开(公告)日：2014-07-17

    申请号：US13740183

    申请日：2013-01-12

    申请人： Terence Gilhuly

    发明人： Terence Gilhuly

    IPC分类号： A61M16/04 ,  A61M25/00

    CPC分类号： A61M16/044 ,  A61M16/0409 ,  A61M16/0434 ,  A61M16/209

    摘要： Under- and overinflation of retention balloons and cuffs for catheters including Foley catheters, and for endotracheal tubes, tracheostomy tubes, laryngeal mask airways and similar devices is correlated with hospital acquired infections and with patient injury. In this patent, a solution that correctly inflates inflatable retention devices is taught, whereby a pressure release means is incorporated into the inflation pathway from the fluid input syringe to the retention means while inflating. This pressure release means can be set to open at or near the optimal fluid pressure so that overinflation can be prevented by releasing any pressure above the optimal pressure and underinflation can be prevented by a user pressurizing the cuff until the valve is noticed to open. As well, observation of fluid leaked through the pressure relief means can indicate misplacement of the retention means, allowing the user to reposition it before patient injury occurs. The invention is presented as a standalone part and in a format whereby the invention is integrated into existing airway cuff inflation designs.

    摘要翻译： 用于导管（包括Foley导管）和气管内导管，气管造口管，喉罩气道和类似装置的保留气囊和袖带的欠充和过度充气与医院获得性感染和患者损伤相关。 在该专利中，教导了可充气保持装置正确膨胀的解决方案，由此在膨胀期间将压力释放装置并入到从流体输入注射器到保持装置的充气路径中。 该压力释放装置可以被设置为在最佳流体压力处或接近最佳流体压力下打开，从而可以通过释放高于最佳压力的任何压力来防止过度充气，并且可以通过用户对袖带的压力来防止欠充气，直到阀被注意到打开。 同样，观察通过压力释放装置泄漏的流体可以指示保持装置的错位，允许使用者在患者发生伤害之前重新定位它。 本发明被呈现为独立的部分，并且以将本发明整合到现有的气道袖带充气设计的格式中呈现。

    Modeling and control for highly variable and nonlinear systems
    7.
    发明授权
    Modeling and control for highly variable and nonlinear systems 有权
    高度可变和非线性系统的建模与控制

    公开(公告)号：US08229872B2

    公开(公告)日：2012-07-24

    申请号：US12311104

    申请日：2007-09-14

    申请人： Terence Gilhuly

    发明人： Terence Gilhuly

    IPC分类号： G06F17/00 ,  G06N5/02

    CPC分类号： A61B5/05 ,  A61B5/0002 ,  A61B5/01 ,  A61B5/02055 ,  A61B5/1106 ,  A61B5/4821 ,  A61B5/72 ,  A61B5/746 ,  A61M2005/14208 ,  G05B17/02 ,  G06F19/00 ,  G06F19/3456 ,  G16H50/50 ,  Y02A90/26

    摘要： The present invention relates generally to methods of modeling and handling of nonlinearities for application of automatic control to systems with high inter-process variance and nonlinearities. The variance and nonlinearities make these systems difficult to control. Variance is accounted for by replacing the mathematical model of the system with a more representative model from a modelset that may or may not be chosen based on characteristics of the system under test, and then adapting using recursive estimation techniques. Nonlinearities defined by threshold to response and maximal responses are incorporated into linear models relating accumulated inputs to response. Example implementations in relation to automated drug delivery for neuromuscular blocking drugs through warning, advisory and closed-loop control systems are discussed.

    摘要翻译： 本发明一般涉及用于将自动控制应用于具有高过程间变化和非线性的系统的非线性建模和处理的方法。 方差和非线性使得这些系统难以控制。 通过用可能或可能不会根据被测系统的特性来选择的模型组中的更具代表性的模型来替代系统的数学模型，然后使用递归估计技术进行调整来解释差异。 由阈值响应和最大响应定义的非线性被并入到将累积输入与响应相关联的线性模型中。 讨论了通过警告，咨询和闭环控制系统与神经肌肉阻滞药物自动化药物递送有关的实例。

    Sensors and sensing for monitoring neuromuscular blockade
    9.
    发明授权
    Sensors and sensing for monitoring neuromuscular blockade 有权
    用于监测神经肌肉阻滞的传感器和传感器

    公开(公告)号：US08506502B2

    公开(公告)日：2013-08-13

    申请号：US12311105

    申请日：2007-09-14

    申请人： Terence Gilhuly

    发明人： Terence Gilhuly

    IPC分类号： A61B5/05

    CPC分类号： A61B5/05 ,  A61B5/0002 ,  A61B5/01 ,  A61B5/02055 ,  A61B5/1106 ,  A61B5/4821 ,  A61B5/72 ,  A61B5/746 ,  A61M2005/14208 ,  G05B17/02 ,  G06F19/00 ,  G06F19/3456 ,  G16H50/50 ,  Y02A90/26

    摘要： Improved sensors and sensing methods for detection of Neuromuscular Blockade (NMB), for example to improve monitoring generally, as well as facilitate automated NMB drug administration. The methods, systems, devices, etc., herein can increase the quantity and quality of data available. The methods, etc., include translation between commonly available sensing types, use of partially saturated sensor measurements, use of a model of neurotransmitter storage and release and sophisticated use of more than one sensor simultaneously. These methods are aided by new sensors and methods of decreasing electrical noise. An implementation of the methods, systems, devices, etc., herein is automated drug delivery for NMB, whether through an advisor system or through with full computer control.

    摘要翻译： 改进的用于检测神经肌肉阻滞（NMB）的传感器和感测方法，例如通常改善监测，以及促进自动NMB药物给药。 这里的方法，系统，设备等可以增加可用数据的数量和质量。 方法等包括通常可用的感测类型之间的翻译，部分饱和传感器测量的使用，神经递质储存和释放的模型的使用以及同时多个传感器的复杂使用。 这些方法得到了新的传感器和降低电噪声的方法的帮助。 这里的方法，系统，设备等的实现是NMB的自动化药物递送，无论是通过顾问系统还是通过全面的计算机控制。