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公开(公告)号：US20080221672A1
公开(公告)日：2008-09-11
申请号：US12028572
申请日：2008-02-08
申请人： David G. Lamphere , Tuan Anh Nguyen , Howard C. Herrmann , Todd C. Tomba , Robert C. Gorman , Joseph H. Gorman
发明人： David G. Lamphere , Tuan Anh Nguyen , Howard C. Herrmann , Todd C. Tomba , Robert C. Gorman , Joseph H. Gorman
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2/2439 , A61F2220/0016 , A61F2220/0075 , A61F2230/008
摘要： Valve prostheses are disclosed that are adapted for secure and aligned placement relative to a heart annulus. The valve prostheses may be placed in a non-invasive manner, e.g., via trans-catheter techniques. The valve prosthesis may include a resilient ring, a plurality of leaflet membranes mounted with respect to the resilient ring, and a plurality of positioning elements movably mounted with respect to the flexible ring. Each of the positioning elements defines respective proximal, intermediate, and distal tissue engaging regions cooperatively configured and dimensioned to simultaneously engage separate corresponding areas of the tissue of an anatomical structure, including respective first, second, and third elongate tissue-piercing elements. The proximal, distal, and intermediate tissue-engaging regions are cooperatively configured and dimensioned to simultaneously engage separate corresponding areas of the tissue of an anatomical structure so as to stabilize a position of the valve prosthesis with respect to the anatomical structure, including wherein for purposes of so simultaneously engaging the separate corresponding areas of tissue, at least one of the first, second, and third elongate tissue-piercing elements is pointed at least partially opposite the direction of blood flow, and at least another thereof is pointed at least partially along the direction of blood flow. The valve prosthesis may also include a skirt mounted with respect to the resilient ring for sealing a periphery of the valve prosthesis against a reverse flow of blood around the valve prosthesis.
摘要翻译： 公开了适于相对于心脏环的安全和对准放置的阀门假体。 瓣膜假体可以以非侵入性方式放置，例如通过反式导管技术。 瓣膜假体可以包括弹性环，相对于弹性环安装的多个传膜，以及相对于柔性环可移动地安装的多个定位元件。 每个定位元件限定相应的近端，中间和远侧组织接合区域，其协作地构造和尺寸设计成同时接合解剖结构的组织的分开的对应区域，包括相应的第一，第二和第三细长组织刺穿元件。 近端，远端和中间组织接合区域协同地构造和尺寸设计以同时接合解剖结构的组织的分开的对应区域，以便相对于解剖结构稳定瓣膜假体的位置，包括其中为了目的 同时接合组织的单独的对应区域，第一，第二和第三细长组织刺穿元件中的至少一个至少部分地相对于血流方向指向，并且至少另一个至少部分地沿着 血流方向。 瓣膜假体还可以包括相对于弹性环安装的裙部，用于抵抗瓣膜假体周围的逆流血液密封阀门假体的周边。
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2.发明授权Method of using a spring-loaded reciprocable stylet holder to eject a T-fastener 失效使用弹簧加载的往复式探针支架来弹出T型紧固件的方法
公开(公告)号：US5531678A
公开(公告)日：1996-07-02
申请号：US422297
申请日：1995-04-14
CPC分类号： A61B17/0401 , A61B50/22 , A61B17/0469 , A61B17/06061 , A61B17/06133 , A61B17/8695 , A61B2017/0406 , A61B2017/0409 , A61B2017/0416 , A61B2017/0417 , A61B2017/0454 , A61B2017/0464 , A61B2017/06142
摘要： A spring-loaded reciprocable stylet holder assembly includes a cap; a hollow body element partially nested within and reciprocable a major part of its length into the cap; a spring urging the body element outwardly of the cap; and a stylet supported at one end by the cap and extending through and beyond the body element. The remote end of the body element has a small borehole through which the stylet extends. The remote end is also provided with attachment means for a hypodermic needle with slotted tip for T-fastener emplacement, the needle telescopically surrounding the full length of the stylet. In a useful modification of the device an insufflation adapter having a side port for attachment of a hypodermic syringe is placed in line between the body element and the hypodermic needle. The stylet holder assembly with a slotted hypodermic needle attached thereto may be used for emplacing a T-fastener in a hollow organ of a person, such as the stomach.
摘要翻译： 弹簧加载的往复式通心针保持器组件包括盖; 中空体元件部分地嵌套在其长度的主要部分中并且可往复运动到盖中; 弹簧将身体元件推向帽子外部; 并且探针在一端由帽支撑并且延伸穿过身体元件并且超出身体元件。 身体元件的远端具有小的钻孔，探针延伸穿过该孔。 远端还设置有用于皮下注射针的连接装置，其具有用于T型紧固件插入的开槽尖端，该针可伸缩地围绕探针的全长。 在设备的有用修改中，具有用于附着皮下注射器的侧端口的吹入适配器被放置在身体元件和皮下注射针之间。 具有连接到其上的开槽皮下注射针的探针支架组件可以用于在人的中空器官（例如胃）中放置T形紧固件。
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公开(公告)号：US08070802B2
公开(公告)日：2011-12-06
申请号：US12028572
申请日：2008-02-08
申请人： David G. Lamphere , Tuan Anh Nguyen , Howard C. Herrmann , Todd C. Tomba , Robert C. Gorman , Joseph H. Gorman, III
发明人： David G. Lamphere , Tuan Anh Nguyen , Howard C. Herrmann , Todd C. Tomba , Robert C. Gorman , Joseph H. Gorman, III
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2/2439 , A61F2220/0016 , A61F2220/0075 , A61F2230/008
摘要： Valve prostheses are disclosed that are adapted for secure and aligned placement relative to a heart annulus. The valve prostheses may be placed in a non-invasive manner, e.g., via transcatheter techniques. The valve prosthesis may include a resilient ring, a plurality of leaflet membranes mounted with respect to the resilient ring, and a plurality of positioning elements movably mounted with respect to the flexible ring. Each of the positioning elements defines respective proximal, intermediate, and distal tissue engaging regions cooperatively configured and dimensioned to simultaneously engage separate corresponding areas of the tissue of an anatomical structure, including respective first, second, and third elongate tissue-piercing elements. The proximal, distal, and intermediate tissue-engaging regions are cooperatively configured and dimensioned to simultaneously engage separate corresponding areas of the tissue of an anatomical structure so as to stabilize a position of the valve prosthesis with respect to the anatomical structure, including wherein for purposes of so simultaneously engaging the separate corresponding areas of tissue, at least one of the first, second, and third elongate tissue-piercing elements is pointed at least partially opposite the direction of blood flow, and at least another thereof is pointed at least partially along the direction of blood flow. The valve prosthesis may also include a skirt mounted with respect to the resilient ring for sealing a periphery of the valve prosthesis against a reverse flow of blood around the valve prosthesis.
摘要翻译： 公开了适于相对于心脏环的安全和对准放置的阀门假体。 瓣膜假体可以以非侵入性方式放置，例如通过经导管技术。 瓣膜假体可以包括弹性环，相对于弹性环安装的多个传膜，以及相对于柔性环可移动地安装的多个定位元件。 每个定位元件限定相应的近端，中间和远侧组织接合区域，其协作地构造和尺寸设计成同时接合解剖结构的组织的分开的对应区域，包括相应的第一，第二和第三细长组织刺穿元件。 近端，远端和中间组织接合区域协同地构造和尺寸设计以同时接合解剖结构的组织的分开的对应区域，以便相对于解剖结构稳定瓣膜假体的位置，包括其中为了目的 同时接合组织的单独的对应区域，第一，第二和第三细长组织刺穿元件中的至少一个至少部分地相对于血流方向指向，并且至少另一个至少部分地沿着 血流方向。 瓣膜假体还可以包括相对于弹性环安装的裙部，用于抵抗瓣膜假体周围的逆流血液密封阀门假体的周边。
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公开(公告)号：US5531699A
公开(公告)日：1996-07-02
申请号：US308242
申请日：1994-09-19
CPC分类号： A61B17/0401 , A61B50/22 , A61B17/0469 , A61B17/06061 , A61B17/06133 , A61B17/8695 , A61B2017/0406 , A61B2017/0409 , A61B2017/0416 , A61B2017/0417 , A61B2017/0454 , A61B2017/0464 , A61B2017/06142
摘要： A spring-loaded reciprocable stylet holder assembly includes a cap; a hollow body element partially nested within and reciprocable a major part of its length into the cap; a spring urging the body element outwardly of the cap; and a stylet supported at one end by the cap and extending through and beyond the body element. The remote end of the body element has a small borehole through which the stylet extends. The remote end is also provided with attachment means for a hypodermic needle with slotted tip for T-fastener emplacement, the needle telescopically surrounding the full length of the stylet. In a useful modification of the device an insufflation adapter having a side port for attachment of a hypodermic syringe is placed in line between the body element and the hypodermic needle. The stylet holder assembly with a slotted hypodermic needle attached thereto may be used for emplacing a T-fastener in a hollow organ of a person, such as the stomach.
摘要翻译： 弹簧加载的往复式通心针保持器组件包括盖; 中空体元件部分地嵌套在其长度的主要部分中并且可往复运动到盖中; 弹簧将身体元件推向帽子外部; 并且探针在一端由帽支撑并且延伸穿过身体元件并且超出身体元件。 身体元件的远端具有小的钻孔，探针延伸穿过该孔。 远端还设置有用于皮下注射针的连接装置，其具有用于T型紧固件插入的开槽尖端，该针可伸缩地围绕探针的全长。 在设备的有用修改中，具有用于附着皮下注射器的侧端口的吹入适配器被放置在身体元件和皮下注射针之间。 具有连接到其上的开槽皮下注射针的探针支架组件可以用于在人的中空器官（例如胃）中放置T形紧固件。
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