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公开(公告)号:US10888529B2
公开(公告)日:2021-01-12
申请号:US16091071
申请日:2017-04-04
摘要: The invention relates to a nanoparticle comprising: (i) between 60 wt.-% and 99 wt.-% sorbitan ester, relative to the total weight of the nanoparticle; (ii) a positively charged substance; and (iii) a miRNA. The invention also relates to the methods for producing same and to the uses thereof, particularly for therapeutic uses, such as cancer treatment.
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公开(公告)号:US20190111002A1
公开(公告)日:2019-04-18
申请号:US16091071
申请日:2017-04-04
申请人: UNIVERSIDADE DE SANTIAGO DE COMPOSTELA , UNIVERSIDAD DEL PAIS VASCO - EUSKAL HERRIKO UNIBERTSITATEA (UPV/EHU)
IPC分类号: A61K9/51 , A61K31/7105
摘要: The invention relates to a nanoparticle comprising: (i) between 60 wt.-% and 99 wt.-% sorbitan ester, relative to the total weight of the nanoparticle; (ii) a positively charged substance; and (iii) a miRNA. The invention also relates to the methods for producing same and to the uses thereof, particularly for therapeutic uses, such as cancer treatment.
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3.
公开(公告)号:US20180050908A1
公开(公告)日:2018-02-22
申请号:US15553058
申请日:2016-02-19
发明人: Alexander LÓPEZ URIONABARRENECHEA , Isabel DE MARCO RODRÍGUEZ , Blanca María CABALLERO IGLESIAS , Naia GASTELU OTAZUA , Ainhoa HERNÁNDEZ SÁINZ , Aitziber ADRADOS LÓPEZ DE VIÑASPRE , Jon SOLAR IRAZABAL
CPC分类号: C01B3/40 , B01D53/002 , B01D53/8668 , B01D2255/20753 , B01D2255/50 , B01J23/40 , B01J23/58 , B01J23/60 , B01J23/63 , B01J23/755 , B01J29/068 , B01J29/072 , B01J29/46 , B01J35/04 , B01J37/0201 , B01J37/0215 , B01J37/0246 , B01J37/0248 , B01J37/18 , B01J2229/186 , B29B17/02 , B29B17/04 , B29B2017/0496 , B29K2307/04 , C01B3/26 , C01B2203/0227 , C01B2203/0277 , C01B2203/1023 , C01B2203/1058 , C01B2203/1082 , C10B53/07 , C10K1/20 , C10K1/32 , C10K1/34
摘要: A method for treating vapours generated during the pyrolysis of carbon fibre composites, such as production waste generated by the producers or composites of carbon fibre at the end of the service life thereof, includes, passing the vapours through a reactor which is at a high temperature and contains a solid material filler (solid bed), for example CSi, and optionally also a solid catalyst having an acid and/or reforming function, preferably both, for example a transition metal supported on an acid substrate, such as Ni on zeolite. Following the condensation of the vapours resulting from the treatment, an improved aqueous liquid phase, a minimum or non-existent organic fraction and a gaseous phase of increased added value are obtained.
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公开(公告)号:US20190271675A1
公开(公告)日:2019-09-05
申请号:US16345001
申请日:2017-10-26
摘要: An ion gel including a hydrogel in an ionic liquid, and a reactive system that changes colour upon reaction with the nitrite and a microfluidic device having a substrate with calibration reservoirs that are separated from one another and include an ion gel, a calibration reservoir of the hydrogel in the ionic liquid, a reservoir for holding a sample to be analysed, connected to a measuring reservoir including an ion gel via a microfluidic channel with a reducing agent, and a measuring reservoir including an ion gel of the invention where a sample to be analysed is held and methods for producing the ion gel and the device, as well as a method for colorimetrically determining and detecting nitrite and nitrate in contaminated water using the ion gel and the device.
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公开(公告)号:US20190160618A1
公开(公告)日:2019-05-30
申请号:US16305006
申请日:2017-05-11
申请人: UNIVERSIDAD DEL PAIS VASCO - EUSKAL HERRIKO UNIBERTSITATEA (UPV/EHU) , FUNDACIÓN TECNALIA RESEARCH & INNOVATION
发明人: Octavio Manuel PEREIRA NETO , Adrián RODRÍGUEZ EZQUERRO , López De Lacalle Marcaide LUIS , Franck Andrés GIROT MATA , Mariluz PENALVA OSCOZ , Rivero Rastrero MARIA ASUNCIÓN
IPC分类号: B23Q11/10
摘要: A device for cooling and lubricating a tool during a chip removal machining process, which includes: a first subsystem for cryogenic cooling that includes: a first entry configured to introduce CO2 in liquid state in a first conduit of the device; a first exit configured to supply CO2 in liquid state from a second conduit of the device; a third conduit located between the first and second conduit; and means for preventing the formation of dry ice in the first, second and third conduits; and a second subsystem for lubrication that includes means for supplying micro-particles of a cutting oil in liquid state; wherein the first subsystem and second subsystem are independent from each other, and wherein the first subsystem and second subsystem are configured to act either simultaneously or either one alone. Method of operation of the device.
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公开(公告)号:US11977254B2
公开(公告)日:2024-05-07
申请号:US17620187
申请日:2020-06-24
CPC分类号: G02B6/02042 , G01B11/161 , G01D5/35306
摘要: A composed multicore optical fiber (MCF) device includes a first segment (MCF1) of a MCF having three coupled identical cores and having a first length (L1) and a second segment (MCF2) of the same MCF having a second length (L2). L1 and L2 are different from each other. One of the three coupled cores is located in a geometrical centre of the MCF. The first segment (MCF1) and the second segment (MCF2) of the MCF are rotated 180° relative to each other and spliced together. The first segment (MCF1) is spliced to a first segment (SMF1) of a single mode fiber (SMF) and the second segment (MCF2) is spliced to a second segment (SMF2) of the SMF. The free end of the second segment (SMF2) of the SMF is coupled to a mirror (M) to reflect an optical signal coming from the first segment (SMF1) of the SMF.
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公开(公告)号:US11951579B2
公开(公告)日:2024-04-09
申请号:US16305006
申请日:2017-05-11
申请人: UNIVERSIDAD DEL PAIS VASCO—EUSKAL HERRIKO UNIBERTSITATEA (UPV/EHU) , FUNDACIÓN TECNALIA RESEARCH & INNOVATION
发明人: Octavio Manuel Pereira Neto , Adrián Rodríguez Ezquerro , López De Lacalle Marcaide Luis , Franck Andrés Girot Mata , Mariluz Penalva Oscoz , Rivero Rastrero Maria Asunción
CPC分类号: B23Q11/1046 , B23Q11/1061 , B23Q11/1084 , F16N7/32 , F16N13/22 , F16N2270/70 , Y02P70/10
摘要: A device for cooling and lubricating a tool during a chip removal machining process, which includes: a first subsystem for cryogenic cooling that includes: a first entry configured to introduce CO2 in liquid state in a first conduit of the device; a first exit configured to supply CO2 in liquid state from a second conduit of the device; a third conduit located between the first and second conduit; and means for preventing the formation of dry ice in the first, second and third conduits; and a second subsystem for lubrication that includes means for supplying micro-particles of a cutting oil in liquid state; wherein the first subsystem and second subsystem are independent from each other, and wherein the first subsystem and second subsystem are configured to act either simultaneously or either one alone. Method of operation of the device.
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公开(公告)号:US20220342145A1
公开(公告)日:2022-10-27
申请号:US17620187
申请日:2020-06-24
摘要: A composed multicore optical fiber (MCF) device includes a first segment (MCF1) of a MCF having three coupled identical cores and having a first length (L1) and a second segment (MCF2) of the same MCF having a second length (L2). L1 and L2 are different from each other. One of the three coupled cores is located in a geometrical centre of the MCF. The first segment (MCF1) and the second segment (MCF2) of the MCF are rotated 180° relative to each other and spliced together. The first segment (MCF1) is spliced to a first segment (SMF1) of a single mode fiber (SMF) and the second segment (MCF2) is spliced to a second segment (SMF2) of the SMF. The free end of the second segment (SMF2) of the SMF is coupled to a mirror (M) to reflect an optical signal coming from the first segment (SMF1) of the SMF.
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9.
公开(公告)号:US20190131476A1
公开(公告)日:2019-05-02
申请号:US16306716
申请日:2017-06-02
申请人: Universidad del Pais Vasco – Euskal Herriko Unibertsitatea (UPV/EHU) , Universidad Politécnica de Madrid
发明人: Juan Carlos Jimeno Cuesta , José Rubén Gutiérrez Serrano , Vanesa Fano Lestón , Carlos Del Cañizo Nadal
IPC分类号: H01L31/0687 , H01L31/0224 , H01L31/0216 , H01L31/18 , H01L31/05
摘要: A photovoltaic cell (Ci) comprising at least one sub-cell of a first semiconductor (1) and a sub-cell of a second semiconductor (2) connected by means of three electrodes (T1, T2, T3). The second semiconductor is typically silicon, while the first semiconductor is a material with wider band-gap deposited closer to a surface of incidence of electromagnetic radiation. The first electrode (T1) is on the forward face of the photovoltaic cell (Ci), while the second electrode (T2) and the third electrode (T3) are on the rear face of said photovoltaic cell (Ci). Both the second electrode (T2) and the third electrode (T3) are connected to the second semiconductor (2). The regions on both sides of the area of contact between the first semiconductor and the second semiconductor have the same type of majority carriers. Thus, a photovoltaic cell (Ci) is achieved with a high conversion efficiency that is capable of being integrated into devices with two terminals.
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