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1.发明公开公开(公告)号：US20240218458A1
公开(公告)日：2024-07-04
申请号：US18332359
申请日：2023-06-09
申请人： University of Maryland, Baltimore , University of Maryland, Baltimore County , The Penn State Research Foundation
发明人： Dipanjan Pan , Parikshit Moitra , Ketan Dighe
CPC分类号： C12Q1/689 , C12N9/22 , C12N15/11 , C12N2310/20
摘要： The present invention provides methods of detecting the presence or absence of nucleic acid from Chlamydia trachomatis and the presence or absence of nucleic acid from Neisseria gonorrhoeae in a sample from a subject using CRISPR nucleases and crRNAs specific for Chlamydia trachomatis and Neisseria gonorrhoeae nucleic acid, kits for carrying out the methods and methods of treating subjects infected with Chlamydia trachomatis and/or Neisseria gonorrhoeae.
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公开(公告)号：US11921013B2
公开(公告)日：2024-03-05
申请号：US18048567
申请日：2022-10-21
发明人： Weidong Zhu , Linfeng Lyu
摘要： A one-dimensional (1D) and two-dimensional (2D) scan scheme for a tracking continuously scanning laser Doppler vibrometer (CSLDV) system to scan the whole surface of a rotating structure excited by a random force. A tracking CSLDV system tracks a rotating structure and sweep its laser spot on its surface. The measured response of the structure using the scan scheme of the tracking CSLDV system is considered as the response of the whole surface of the structure subject to random excitation. The measured response can be processed by operational modal analysis (OMA) methods (e.g., an improved lifting method, an improved demodulation method, an improved 2D demodulation method). Damped natural frequencies of the rotating structure are estimated from the fast Fourier transform of the measured response. Undamped full-field mode shapes are estimated by multiplying the measured response using sinusoids whose frequencies are estimated damped natural frequencies.
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公开(公告)号：US11859716B2
公开(公告)日：2024-01-02
申请号：US17723805
申请日：2022-04-19
发明人： Weidong Zhu , Gang Li , Meilin Yu , Xuefeng Wang
CPC分类号： F16H61/664 , F16H3/76 , F16H59/40 , F16H59/42 , F16H59/70 , F16H59/44 , F16H2059/704 , F16H2061/009 , F16H2061/0096
摘要： A tidal current energy converter including an infinitely variable transmission (IVT) control system and a hybrid vertical axis wind (or water) turbine (VAWTs) apparatus. The hybrid VAWT apparatus includes a modified-Savonius (MS) rotor in the central region and a straight bladed H-type Darrieus rotor in the surrounding annular region. The IVT control system includes a nonlinear closed-loop control combined with an integral time-delay feedback control to adjust a speed ratio of the IVT. A speed ratio control for an IVT system involves a forward speed controller and/or a crank length controller for different speed ranges. The time-delay control is designed to reduce speed fluctuations of the output speed of an IVT with an accurate speed ratio. The speed ratio of an IVT with the disclosed control strategy can achieve an excellent tracking response for the desired constant output speed and reduce speed fluctuations of the output speed of an IVT by the time-delay feedback control.
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公开(公告)号：US20230407230A1
公开(公告)日：2023-12-21
申请号：US18329112
申请日：2023-06-05
摘要： The present invention relates to cell free protein manufacturing, and more particularly, for integrating machine learning into a portable cell-free bioprocessing system for producing proteins with increased and consistent purity, potency and quality wherein such proteins are prepared on-demand and for point-of-care delivery.
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公开(公告)号：US20230404934A1
公开(公告)日：2023-12-21
申请号：US18299135
申请日：2023-04-12
发明人： Erin LAVIK , Sydney MENIKHEIM , Joshua LECKRON
IPC分类号： A61K9/51 , A61K41/00 , A61K31/473 , A61K31/4418 , A61P27/02 , A61K9/00
CPC分类号： A61K9/5146 , A61K9/5192 , A61K41/0047 , A61K31/473 , A61K31/4418 , A61P27/02 , A61K9/0048
摘要： A long-term delivery system for age-related macular degeneration (AMD) that can address the multifactorial nature of the disease. A polyurethane nanocapsule is disclosed that includes encapsulated molecules that treat AMD. The molecules can be passively delivered from the polyurethane nanocapsules over many weeks or months and/or can be tuned, non-invasively, using ultrasound to trigger the release the molecules from the polyurethane nanocapsules repeatedly in an on-demand and predictable manner. These nanocapsules have the potential to change the way diseases are treated and provide a new ultrasound-triggered drug delivery platform.
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6.发明公开公开(公告)号：US20230323488A1
公开(公告)日：2023-10-12
申请号：US18298540
申请日：2023-04-11
发明人： Govind RAO , Xudong GE , Douglas D. FREY , Sai Sathish RAMAMURTHY , Dipanjan PAN
IPC分类号： C12Q1/70 , C12Q1/6844 , G01N33/569 , G01N1/40 , B01L3/00 , G01N33/543
CPC分类号： C12Q1/701 , C12Q1/6844 , G01N33/56983 , G01N1/40 , B01L3/502761 , G01N33/54386 , G01N2333/165 , B01L2200/0652 , B01L2200/16
摘要： The present invention relates to the use of a condensate collector such as portable or stationary dehumidifier placed in a defined testing space or area and used as a readily available and affordable tool to collect airborne virus particles in collected condensate from the testing atmosphere in the defined testing space or area, wherein the collected condensate is analyzed for virus biomarkers to identify viruses, such as SARS-CoV-2 or mutants or variants thereof, in the testing atmosphere.
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公开(公告)号：US20230171165A1
公开(公告)日：2023-06-01
申请号：US17948906
申请日：2022-09-20
发明人： Karuna JOSHI , Timothy FININ , Yelena YESHA
IPC分类号： H04L41/5006 , H04L41/5051 , H04L41/22
CPC分类号： H04L41/5006 , H04L41/5051 , H04L41/22 , G06F3/0482
摘要： This invention relates to methods and systems of procuring services in the cloud and specifically procurement where the requirements are defined by the consumer in a machine understandable knowledge representation language such as RDF and OWL using semantic web technology to establish a cloud agent for discovery of a service provider and effectuate the automatic generation of a contract, or service-level agreement, that can be monitored due to the coupling between the machine understandable knowledge representation language and the contract.
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公开(公告)号：US20220131187A1
公开(公告)日：2022-04-28
申请号：US17508108
申请日：2021-10-22
发明人： Deepa MADAN , Aswani POOSAPATI
IPC分类号： H01M10/0565 , H01M10/36 , H01M4/66 , H01M4/36 , H01M4/48
摘要： Zinc electrolytic manganese dioxide (EMD) batteries including a high performing flexible chitosan-based gel electrolyte with poly-vinyl alcohol (PVA) and potassium hydroxide (KOH) additives were prepared. The Zn-EMD batteries were constructed using an optimized assembly technique employed to achieve good interfacial contact between the layers. Attaining energy densities between 150-250 Wh/kg (w.r.t cathode mass) is possible for these batteries, encouraging their use in wearable or flexible electronics. Using the chitosan-based gel electrolyte and limited voltage window testing, the prepared Zn-EMD alkaline batteries are among the best reported polymer-based alkaline electrolyte Zn rechargeable batteries.
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公开(公告)号：US11268615B2
公开(公告)日：2022-03-08
申请号：US17232225
申请日：2021-04-16
发明人： Weidong Zhu , Xuefeng Wang , Gang Li
摘要： A nonlinear closed-loop control combined with an integral time-delay feedback control is disclosed to adjust a speed ratio of an infinitely variable transmission (IVT) system. A speed ratio control for an IVT system involves a forward speed controller and a crank length controller for different speed ranges. The time-delay control is designed to reduce speed fluctuations of the output speed of an IVT with an accurate speed ratio. The speed ratio of an IVT with the disclosed control strategy can achieve an excellent tracking response for the desired constant output speed and reduce speed fluctuations of the output speed of an IVT by the time-delay feedback control.
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公开(公告)号：US20210380915A1
公开(公告)日：2021-12-09
申请号：US17407392
申请日：2021-08-20
发明人： GOVIND RAO , YORDAN KOSTOV , MICHAEL TOLOSA , XUDONG GE , VIKASH KUMAR , Vida Rahmatnejad
摘要： The present invention relates to collapsible and/or foldable fermentation and/or culture vessels fabricated of an adjustable frame including sections of gas permeable material or in the alternative a non-rigid gas permeable polymeric container or bag fabricated of either a gas permeable or non-gas permeable material with the further benefit of more efficient inventory space and disposal space, wherein the gas permeable material or non-gas permeable material comprises an analyte or pH sensing material integrated or impregnated into at least one section of the material.
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