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公开(公告)号：US10252270B2
公开(公告)日：2019-04-09
申请号：US15509376
申请日：2015-09-08
申请人： Uwe Weierstall , Dingjie Wang , John Spence
发明人： Uwe Weierstall , Dingjie Wang , John Spence
摘要： Nozzle Assemblies and methods of use for producing a liquid jet are disclosed that may be permit adjustable time delays between mixing of fluids and observation of reactions. An example nozzle assembly includes: a housing having an inlet and an outlet and a first channel defined therebetween, where the housing includes a gas focusing aperture defining the housing outlet; an intermediate tube disposed within the first channel of the housing, where the intermediate tube has an inlet and an outlet and defines a second channel therebetween; and a central tube disposed within the second channel of the intermediate tube, where the central tube has an inlet and an outlet and defines a third channel therebetween, where the central tube outlet is longitudinally spaced apart from the intermediate tube outlet such that the intermediate tube outlet is disposed between the central tube outlet and the gas focusing aperture's inlet.
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2.发明申请Methods and Devices for Rapidly Forming Vitreous Ice-Jacketed Particle Droplets 审中-公开快速形成玻璃体冰封颗粒水滴的方法和装置公开(公告)号：US20080283775A1
公开(公告)日：2008-11-20
申请号：US11908319
申请日：2006-03-14
申请人： Bruce Doak , John Spence , Uwe Weierstall
发明人： Bruce Doak , John Spence , Uwe Weierstall
CPC分类号： A01N1/02 , A01N1/0257 , A01N1/0278 , G01N1/42 , G01N15/0211
摘要： The present invention provides methods and devices for rapidly forming vitreous ice-jacketed particle droplets.
摘要翻译： 本发明提供用于快速形成玻璃状冰夹层颗粒液滴的方法和装置。
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公开(公告)号：US20210001359A1
公开(公告)日：2021-01-07
申请号：US16918807
申请日：2020-07-01
申请人： Richard Kirian , Reza Nazari , Uwe Weierstall , Ronald Adrian
发明人： Richard Kirian , Reza Nazari , Uwe Weierstall , Ronald Adrian
摘要： A nozzle includes a chamber, a first channel formed in the nozzle, and a first passageway extending between the first channel and the chamber. The first passageway defines a first passageway axis. The nozzle also includes a second channel formed in the nozzle and a second passageway extending between the second channel and the chamber. The second passageway defines a second passageway axis, and the first passageway axis is not concentric with the second passageway axis.
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4.发明授权公开(公告)号：US08272576B2
公开(公告)日：2012-09-25
申请号：US12664437
申请日：2008-06-20
申请人： Robert Bruce Doak , John C. H. Spence , Uwe Weierstall , Daniel DePonte , Dmitri Starodub , Jared Scott Warner
发明人： Robert Bruce Doak , John C. H. Spence , Uwe Weierstall , Daniel DePonte , Dmitri Starodub , Jared Scott Warner
IPC分类号： A62C5/02
CPC分类号： B05B7/0475 , B05B1/02
摘要： A nozzle for producing a single-file stream of droplets of a fluid, methods using the nozzle, and an injector, comprising the nozzle of the invention, for providing the single-file stream of droplets of a fluid to a high-vacuum system are described. The nozzle comprises two concentric tubes wherein the outer tube comprises a smoothly converging-diverging exit channel and the outlet end of the first tube is positioned within the converging section of the exit channel.
摘要翻译： 用于产生流体液滴单液流的喷嘴，使用喷嘴的方法和喷射器，其包括本发明的喷嘴，用于向高真空系统提供流体的单液滴流。 描述。 喷嘴包括两个同心管，其中外管包括平稳会聚的发散出口通道，并且第一管的出口端位于出口通道的会聚部分内。
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公开(公告)号：US20170274380A1
公开(公告)日：2017-09-28
申请号：US15509376
申请日：2015-09-08
申请人： Uwe WEIERSTALL , Dingjie WANG , John SPENCE
发明人： Uwe WEIERSTALL , Dingjie WANG , John SPENCE
CPC分类号： B01L3/502776 , B01F3/04007 , B01F3/0865 , B01F5/045 , B01F13/0062 , B01F13/0093 , B01F2215/0037 , B01F2215/0431 , B01L3/5027 , B01L2200/0636 , B01L2300/0832 , B01L2300/0858 , B01L2300/0867 , B05B7/32
摘要： Nozzle Assemblies and methods of use for producing a liquid jet are disclosed that may be permit adjustable time delays between mixing of fluids and observation of reactions. An example nozzle assembly includes: a housing having an inlet and an outlet and a first channel defined therebetween, where the housing includes a gas focusing aperture defining the housing outlet; an intermediate tube disposed within the first channel of the housing, where the intermediate tube has an inlet and an outlet and defines a second channel therebetween; and a central tube disposed within the second channel of the intermediate tube, where the central tube has an inlet and an outlet and defines a third channel therebetween, where the central tube outlet is longitudinally spaced apart from the intermediate tube outlet such that the intermediate tube outlet is disposed between the central tube outlet and the gas focusing aperture's inlet.
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6.发明申请公开(公告)号：US20100243753A1
公开(公告)日：2010-09-30
申请号：US12664437
申请日：2008-06-20
申请人： Robert Bruce Doak , John C.H. Spence , Uwe Weierstall , Daniel DePonte , Dmitri Starodub , Jared Scott Warner
发明人： Robert Bruce Doak , John C.H. Spence , Uwe Weierstall , Daniel DePonte , Dmitri Starodub , Jared Scott Warner
CPC分类号： B05B7/0475 , B05B1/02
摘要： A nozzle for producing a single-file stream of droplets of a fluid, methods using the nozzle, and an injector, comprising the nozzle of the invention, for providing the single-file stream of droplets of a fluid to a high-vacuum system are described. The nozzle comprises two concentric tubes wherein the outer tube comprises a smoothly converging-diverging exit channel and the outlet end of the first tube is positioned within the converging section of the exit channel.
摘要翻译： 用于产生流体液滴单液流的喷嘴，使用喷嘴的方法和喷射器，其包括本发明的喷嘴，用于向高真空系统提供流体的单液滴流。 描述。 喷嘴包括两个同心管，其中外管包括平稳会聚的发散出口通道，并且第一管的出口端位于出口通道的会聚部分内。
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公开(公告)号：US20060262317A1
公开(公告)日：2006-11-23
申请号：US11358237
申请日：2006-02-21
申请人： Bruce Doak , John Spence , Uwe Weierstall
发明人： Bruce Doak , John Spence , Uwe Weierstall
IPC分类号： G01J3/45
CPC分类号： A01N1/02 , A01N1/0257 , A01N1/0278 , G01N1/42 , G01N15/0211
摘要： The present invention provides methods for molecular structure determination using serial diffraction, and devices for carrying out the methods of the invention.
摘要翻译： 本发明提供使用串联衍射的分子结构测定方法以及用于实施本发明的方法的装置。
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