Treatment and Diagnosis of Insulin-Resistant States
    3.
    发明申请
    Treatment and Diagnosis of Insulin-Resistant States 审中-公开
    胰岛素抵抗状态的治疗和诊断

    公开(公告)号:US20060293239A1

    公开(公告)日:2006-12-28

    申请号:US11465956

    申请日:2006-08-21

    IPC分类号: A61K38/22 A61K38/10

    摘要: Dickkopf-5 (Dkk-5) protein is administered in effective amounts to treat disorders involving insulin resistance, such as non-insulin-dependent diabetes mellitus (NIDDM) or obesity. Also provided is a method of diagnosing insulin resistance and related disorders using Dkk-5 as a measure, and kits for diagnosis and treatment, as well as hybridomas producing antibodies to Dkk-5 and preparations comprising Dkk-5.

    摘要翻译: 以有效量施用Dickkopf-5(Dkk-5)蛋白,以治疗涉及胰岛素抵抗的疾病,例如非胰岛素依赖型糖尿病(NIDDM)或肥胖症。 还提供了使用Dkk-5作为测量来诊断胰岛素抵抗和相关疾病的方法,以及用于诊断和治疗的试剂盒,以及产生Dkk-5抗体的杂交瘤和包含Dkk-5的制剂。