公开(公告)号：US08703101B2

公开(公告)日：2014-04-22

申请号：US13388360

申请日：2010-08-03

申请人： Stephanie F. Bernatchez ,  Vinod P. Menon ,  Joseph J. Stoffel ,  Joseph A. Tucker

发明人： Stephanie F. Bernatchez ,  Vinod P. Menon ,  Joseph J. Stoffel ,  Joseph A. Tucker

IPC分类号： A61K49/00

CPC分类号： G01N33/84 ,  G01N2800/40

摘要： The present disclosure provides devices and rapid methods to acquire a wound sample to detect and measure NOx, and optionally, one or more other analytes that are indicative of the status of a wound.

摘要翻译： 本公开提供了用于获取伤口样品以检测和测量NO x的装置和快速方法，以及可选地，指示伤口状态的一种或多种其它分析物。

公开(公告)号：US08617897B2

公开(公告)日：2013-12-31

申请号：US13388564

申请日：2010-08-03

申请人： Vinod P. Menon

发明人： Vinod P. Menon

IPC分类号： G01N33/48 ,  G01N21/78

CPC分类号： G01N33/523 ,  G01N33/526 ,  G01N2800/26 ,  Y10T436/17 ,  Y10T436/173076 ,  Y10T436/177692 ,  Y10T436/179228 ,  Y10T436/25 ,  Y10T436/255

摘要： Methods and kits to detect and quantitate NOx compounds in a biological sample are provided. The methods include reacting a mixture that includes a nitrite compound and a chromogenic reagent to form a colored compound, contacting the mixture with a retention medium configured to retain the colored compound, and detecting the colored compound retained on the retention medium.

摘要翻译： 提供了用于检测和定量生物样品中的NOx化合物的方法和试剂盒。 所述方法包括使包含亚硝酸盐化合物和显色试剂的混合物反应以形成有色化合物，使该混合物与构造成保留着色化合物的保留介质接触，并检测保留在保留介质上的着色化合物。

公开(公告)号：US20120129266A1

公开(公告)日：2012-05-24

申请号：US13388564

申请日：2010-08-03

申请人： Vinod P. Menon

发明人： Vinod P. Menon

IPC分类号： G01N33/48

CPC分类号： G01N33/523 ,  G01N33/526 ,  G01N2800/26 ,  Y10T436/17 ,  Y10T436/173076 ,  Y10T436/177692 ,  Y10T436/179228 ,  Y10T436/25 ,  Y10T436/255

摘要： The present disclosure provides methods and kits to detect and quantitate NOx compounds in a biological sample. The methods include reacting a mixture comprising a nitrite compound a chromogenic reagent to form a colored compound, contacting the mixture with a retention medium configured to retain the colored compound, and detecting the colored compound retained on the retention medium.

摘要翻译： 本公开提供了用于检测和定量生物样品中的NOx化合物的方法和试剂盒。 所述方法包括使包含亚硝酸盐化合物的显色试剂的混合物反应以形成有色化合物，使该混合物与构造成保留着色化合物的保留介质接触，并检测保留在保留介质上的着色化合物。

公开(公告)号：US20110077497A1

公开(公告)日：2011-03-31

申请号：US12990064

申请日：2009-04-29

申请人： Craig D. Oster ,  Hatim M. Carim ,  Casey L. Carlson ,  Vinod P. Menon ,  Jon A. Kirschhoffer ,  William Bedingham ,  Christopher R. Yungers

发明人： Craig D. Oster ,  Hatim M. Carim ,  Casey L. Carlson ,  Vinod P. Menon ,  Jon A. Kirschhoffer ,  William Bedingham ,  Christopher R. Yungers

IPC分类号： A61B5/0408 ,  A61B5/00

CPC分类号： A61B5/0002 ,  A61B5/0006 ,  A61B5/04085 ,  A61B5/04087 ,  A61B5/0416 ,  A61B5/6831 ,  A61B2560/045 ,  A61B2562/17

摘要： A biomedical sensor system. The system can include a sensor adapted to create a signal based on a physiological characteristic from a subject, and a hub adapted to receive the signal from the sensor. The signal can include at least one of an electromagnetic signal, an electrical signal, an acoustic signal, a mechanical signal, a thermal signal, and a chemical signal. The system can further include a connector adapted to couple the sensor and the hub, the connector having a variable length, such that the sensor and the hub can be positioned a variable distance apart by changing the length of the connector. The connector can be adapted to provide a pathway between the sensor and the hub for the signal. A method of applying a biomedical sensor system to a subject can include changing the length of the variable-length connector to provide an appropriate distance between the sensor and the hub, and coupling the sensor to the subject.

摘要翻译： 生物医学传感器系统。 系统可以包括适于基于来自对象的生理特征创建信号的传感器和适于从传感器接收信号的轮毂。 信号可以包括电磁信号，电信号，声信号，机械信号，热信号和化学信号中的至少一个。 该系统还可包括适于联接传感器和轮毂的连接器，连接器具有可变长度，使得传感器和轮毂可以通过改变连接器的长度而位于可变距离之间。 连接器可以适于在传感器和集线器之间提供用于信号的路径。 将生物医学传感器系统应用于对象的方法可以包括改变可变长度连接器的长度以在传感器和轮毂之间提供适当的距离，以及将传感器耦合到对象。

公开(公告)号：US5871671A

公开(公告)日：1999-02-16

申请号：US950574

申请日：1997-10-14

申请人： Patrick J. Kinlen ,  Yiwei Ding ,  Vinod P. Menon

发明人： Patrick J. Kinlen ,  Yiwei Ding ,  Vinod P. Menon

IPC分类号： C08K5/00 ,  C08K5/435 ,  C08L101/00 ,  H01B1/00 ,  H01B1/12

CPC分类号： H01B1/122 ,  H01B1/24

摘要： Organically soluble intrinsically conductive polymer compositions having enhanced electrical conductivity are produced by adding a hygroscopic, water-insoluble plasticizer to an organically soluble intrinsically conductive polymer salt. Polymer blends containing such compositions are also produced by blending a matrix polymer with the plasticizer/ICP salt compositions. Methods for enhancing the electrical conductivity of an organically soluble intrinsically conductive polymer salt provide for the addition of a hygroscopic, water-insoluble plasticizer to an organically soluble intrinsically conductive polymer salt.

摘要翻译： 通过向有机溶解的固有导电聚合物盐中加入吸水性不溶于水的增塑剂来制备具有增强的导电性的有机溶解的本征导电聚合物组合物。 含有这种组合物的聚合物共混物也通过将基质聚合物与增塑剂/ ICP盐组合物共混来制备。 提高有机溶解性本征导电聚合物盐的导电性的方法提供了将吸湿性的水不溶性增塑剂加入到有机溶解的本征导电聚合物盐中。

公开(公告)号：US20120135444A1

公开(公告)日：2012-05-31

申请号：US13388360

申请日：2010-08-03

申请人： Stephanie F. Bernatchez ,  Vinod P. Menon ,  Joseph J. Stoffel ,  Joseph A. Tucker

发明人： Stephanie F. Bernatchez ,  Vinod P. Menon ,  Joseph J. Stoffel ,  Joseph A. Tucker

IPC分类号： G01N33/84 ,  G01N33/52 ,  C12Q1/04 ,  C12Q1/37 ,  G01N33/68 ,  C12Q1/34

CPC分类号： G01N33/84 ,  G01N2800/40

摘要： The present disclosure provides devices and rapid methods to acquire a wound sample to detect the presence of NOx and, optionally, one or more other analytes that are indicative of the status of a wound.

摘要翻译： 本公开提供了用于获取伤口样品以检测NOx的存在的装置和快速方法，以及可选地，指示伤口状态的一种或多种其它分析物。

公开(公告)号：US07999023B2

公开(公告)日：2011-08-16

申请号：US11004158

申请日：2004-12-03

申请人： Vinod P. Menon ,  Jeffrey D. Cotton ,  Terence D. Spawn

发明人： Vinod P. Menon ,  Jeffrey D. Cotton ,  Terence D. Spawn

IPC分类号： C08G73/10 ,  C08K5/06 ,  C08F220/04 ,  C08K5/05 ,  C08K5/101 ,  C08L31/00

CPC分类号： C08F283/06 ,  A61L15/58 ,  A61L15/60 ,  C08L2666/02 ,  C09J151/08

摘要： A process is provided for preparing a pressure sensitive adhesive hydrogel, comprising: (A) providing an oligomeric precursor, the oligomeric precursor comprising a polyether moiety endcapped with ethylenic unsaturation, the oligomeric precursor being associated with methacrylic acid; (B) providing an ethylenically unsaturated crosslinking agent selected from the group consisting of difunctional ethylenically unsaturated monomer, trifunctional ethylenically unsaturated monomer and combinations of the foregoing; (C) free radically curing the oligomeric precursor and the ethylenically unsaturated crosslinking agent in water at a pH between about 3.5 and about 9 to provide the pressure sensitive adhesive hydrogel.

摘要翻译： 提供了一种用于制备压敏粘合剂水凝胶的方法，其包括：（A）提供低聚前体，所述低聚前体包含封端有烯属不饱和键的聚醚部分，所述低聚前体与甲基丙烯酸相结合; （B）提供选自二官能烯属不饱和单体，三官能烯属不饱和单体和前述组合的烯属不饱和交联剂; （C）在约3.5至约9的pH下在水中自由基固化低聚前体和烯属不饱和交联剂，以提供压敏粘合剂水凝胶。

公开(公告)号：US06818118B2

公开(公告)日：2004-11-16

申请号：US09954980

申请日：2001-09-18

申请人： Patrick J. Kinlen ,  Lawrence M. Lawless ,  Vinod P. Menon

发明人： Patrick J. Kinlen ,  Lawrence M. Lawless ,  Vinod P. Menon

IPC分类号： C25D1100

CPC分类号： C25D13/00 ,  C25D11/04

摘要： A method for forming a coating on aluminum by contacting the aluminum with water, at least one multifunctional polymeric organic acid, a monomer of an intrinsically conductive polymer and polymerizing the ICP monomer and forming aluminum oxide by imposing an electrical potential between the aluminum surface as the anode and a cathode. The intrinsically conductive polymer salt and aluminum oxide coating that is formed resists corrosion and is resistant to de-doping during immersion in hot water.

摘要翻译： 通过使铝与水，至少一种多官能聚合有机酸，本征导电聚合物的单体和ICP聚合单体形成铝并通过在铝表面之间施加电位而形成氧化铝来形成铝的涂层的方法， 阳极和阴极。 所形成的本征导电聚合物盐和氧化铝涂层抵抗腐蚀，并且在浸入热水中时耐脱嵌。

公开(公告)号：US06617136B2

公开(公告)日：2003-09-09

申请号：US09841272

申请日：2001-04-24

申请人： Ranjani V. Parthasarathy ,  Raj Rajagopal ,  William Bedingham ,  Michael D. Dirksen ,  Christopher J. Larson ,  Vinod P. Menon

发明人： Ranjani V. Parthasarathy ,  Raj Rajagopal ,  William Bedingham ,  Michael D. Dirksen ,  Christopher J. Larson ,  Vinod P. Menon

IPC分类号： C12P1934

CPC分类号： C12Q1/6844 ,  C12Q2527/125

摘要： Compositions containing a near-IR dye and greater than about 0.5 wt-% of a surfactant selected from the group of a nonionic surfactant, a zwitterionic surfactant, and a mixture thereof, and methods for processing sample materials.

摘要翻译： 含有近红外染料和大于约0.5重量％的选自非离子表面活性剂，两性离子表面活性剂及其混合物的表面活性剂的组合物，以及用于处理样品材料的方法。

公开(公告)号：US07620439B2

公开(公告)日：2009-11-17

申请号：US11197216

申请日：2005-08-04

申请人： Vinod P. Menon ,  Kanta Kumar ,  Carl T. Nelson ,  Don A. Rizzardi

发明人： Vinod P. Menon ,  Kanta Kumar ,  Carl T. Nelson ,  Don A. Rizzardi

IPC分类号： A61B5/04 ,  H01B1/12 ,  H01B1/00

CPC分类号： C09J9/02 ,  A61B5/04087 ,  A61B2562/0215 ,  A61B2562/0217 ,  A61N1/0452 ,  A61N1/0456 ,  A61N1/046 ,  A61N1/0496 ,  C08K5/19 ,  C08L33/06 ,  C08L33/14 ,  C08L71/02 ,  C08L2666/04 ,  C08L2666/14 ,  C09J11/06 ,  C09J133/04 ,  C09J133/06 ,  C09J2201/606 ,  H01B1/20

摘要： A conductive adhesive composition is provided and articles that include the adhesive composition as a component thereof. The conductive adhesive composition comprises: (a) pressure sensitive adhesive; (b) electrolyte comprising water soluble or water dispersible organic chloride; and (c) humectant. In some embodiments, the conductive adhesive composition is a bicontinuous composition comprising an aqueous phase and an oil phase, and the bicontinuous composition may be derived from a polymerizable microemulsion composition, the microemulsion composition comprising: an aqueous phase comprising one or more hydrophilic monomers or oligomers and/or one or more amphiphilic monomers or oligomers in water, the water-soluble or water-dispersible organic chloride, surfactant and humectant; and an oil phase comprising one or more hydrophobic monomers or oligomers. Biomedical articles such as biomedical electrodes, may incorporate the foregoing adhesive as a component.

摘要翻译： 提供了一种导电粘合剂组合物和包含粘合剂组合物作为其组分的制品。 导电粘合剂组合物包括：（a）压敏粘合剂; （b）包含水溶性或水分散性有机氯化物的电解质; 和（c）保湿剂。 在一些实施方案中，导电粘合剂组合物是包含水相和油相的双连续组合物，并且所述双连续组合物可衍生自可聚合微乳液组合物，所述微乳液组合物包含：含有一种或多种亲水性单体或低聚物的水相 和/或水中的一种或多种两亲单体或低聚物，水溶性或水分散性有机氯化物，表面活性剂和湿润剂; 和包含一种或多种疏水性单体或低聚物的油相。 诸如生物医学电极的生物医学制品可以结合前述粘合剂作为组分。