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1.发明授权Compositions and methods for improved isoprene production using two types of ISPG enzymes 有权使用两种类型的ISPG酶改进异戊二烯生产的组合物和方法公开(公告)号：US08685702B2
公开(公告)日：2014-04-01
申请号：US13335768
申请日：2011-12-22
申请人： Rachel E. Muir , Walter Weyler
发明人： Rachel E. Muir , Walter Weyler
CPC分类号： C12P5/007 , C12N9/0006 , C12N9/0093 , C12N9/1022 , C12N9/88 , C12N9/90
摘要： The invention provides for compositions and methods for producing isoprene by using recombinantly engineered cells that utilize a system of dual IspG enzymes in addition to isoprene synthase.
摘要翻译： 本发明提供了通过使用除异戊二烯合酶之外利用双重IspG酶系统的重组工程细胞来生产异戊二烯的组合物和方法。
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公开(公告)号：US08507235B2
公开(公告)日：2013-08-13
申请号：US12817134
申请日：2010-06-16
申请人： Gopal K. Chotani , Joseph C. McAuliffe , Michael C. Miller , Rachel E. Muir , Dmitrii V. Vaviline , Walter Weyler
发明人： Gopal K. Chotani , Joseph C. McAuliffe , Michael C. Miller , Rachel E. Muir , Dmitrii V. Vaviline , Walter Weyler
摘要： The invention provides for methods for producing isoprene from cultured cells using various components of the DXP pathway and MVA pathway, or components associated with the DXP pathway and MVA pathway, iron-sulfur cluster-interacting redox polypeptides, and isoprene synthase. The invention also provides compositions that include these cultured cells.
摘要翻译： 本发明提供了使用DXP途径和MVA途径的各种组分或与DXP途径和MVA途径相关的组分，铁 - 硫簇相互作用的氧化还原多肽和异戊二烯合酶从培养细胞产生异戊二烯的方法。 本发明还提供包括这些培养细胞的组合物。
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公开(公告)号：US08460916B2
公开(公告)日：2013-06-11
申请号：US13540064
申请日：2012-07-02
申请人： Luis G. Cascao-Pereira , Claudine Chang , Clement Choy , James T. Kellis, Jr. , Brian E. Jones , Melodie Estabrook , Marc Koklman , Chris Leeflang , Casper Vroeman , Walter Weyler
发明人： Luis G. Cascao-Pereira , Claudine Chang , Clement Choy , James T. Kellis, Jr. , Brian E. Jones , Melodie Estabrook , Marc Koklman , Chris Leeflang , Casper Vroeman , Walter Weyler
CPC分类号： C12N9/2417 , A21D8/042 , A23K20/189 , A23K50/75 , A23L29/06
摘要： Described are variants (mutants) of a parent alpha-amylase having alpha-amylase activity and exhibiting altered properties relative to the parent alpha-amylase, and methods of use, thereof.
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4.发明申请COMPOSITIONS AND METHODS FOR IMPROVED ISOPRENE PRODUCTION USING TWO TYPES OF ISPG ENZYMES 有权使用两种类型的ISPG酶的改进的异丙苯生产的组合物和方法公开(公告)号：US20120164711A1
公开(公告)日：2012-06-28
申请号：US13335768
申请日：2011-12-22
申请人： Rachel E. MUIR , Walter Weyler
发明人： Rachel E. MUIR , Walter Weyler
CPC分类号： C12P5/007 , C12N9/0006 , C12N9/0093 , C12N9/1022 , C12N9/88 , C12N9/90
摘要： The invention provides for compositions and methods for producing isoprene by using recombinantly engineered cells that utilize a system of dual IspG enzymes in addition to isoprene synthase.
摘要翻译： 本发明提供了通过使用除异戊二烯合酶之外利用双重IspG酶系统的重组工程细胞来生产异戊二烯的组合物和方法。
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5.发明申请Compositions and Uses for an Alpha-Amylase Polypeptide of Bacillus Species 195 失效芽孢杆菌物种的α-淀粉酶多肽的组成和用途195公开(公告)号：US20120142074A1
公开(公告)日：2012-06-07
申请号：US13312555
申请日：2011-12-06
申请人： Neelam S. Amin , Melodie Estabrook , Brian E. Jones , Marc Kolkman , Casper Vroemen , Walter Weyler
发明人： Neelam S. Amin , Melodie Estabrook , Brian E. Jones , Marc Kolkman , Casper Vroemen , Walter Weyler
CPC分类号： C12N9/2417
摘要： Disclosed herein are compositions comprising an alpha-amylase enzyme obtained from Bacillus sp. no. 195, and methods of using the enzyme to clean surfaces and textiles. Also disclosed are variants of the enzyme with different signal sequences.
摘要翻译： 本文公开了包含从芽孢杆菌属（Bacillus sp。）获得的α-淀粉酶的组合物。 没有。 195，以及使用酶清洁表面和纺织品的方法。 还公开了具有不同信号序列的酶的变体。
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公开(公告)号：US20110014672A1
公开(公告)日：2011-01-20
申请号：US12817134
申请日：2010-06-16
申请人： Gopal K. Chotani , Joseph C. Mcauliffe , Michael C. Miller , Rachel Erin Muir , Dmitrii V. Vaviline , Walter Weyler
发明人： Gopal K. Chotani , Joseph C. Mcauliffe , Michael C. Miller , Rachel Erin Muir , Dmitrii V. Vaviline , Walter Weyler
摘要： The invention provides for methods for producing isoprene from cultured cells using various components of the DXP pathway and MVA pathway, or components associated with the DXP pathway and MVA pathway, iron-sulfur cluster-interacting redox polypeptides, and isoprene synthase. The invention also provides compositions that include these cultured cells.
摘要翻译： 本发明提供了使用DXP途径和MVA途径的各种组分或与DXP途径和MVA途径相关的组分，铁 - 硫簇相互作用的氧化还原多肽和异戊二烯合酶从培养细胞产生异戊二烯的方法。 本发明还提供包括这些培养细胞的组合物。
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公开(公告)号：US20130260432A1
公开(公告)日：2013-10-03
申请号：US13436612
申请日：2012-03-30
申请人： Richard R. BOTT , Marguerite A. Cervin , James T. Kellis, JR. , Joseph C. McAuliffe , Andrei Miasnikov , Caroline M. Peres , Christopher Lee Rife , Derek H. Wells , Walter Weyler , Gregory M. Whited
发明人： Richard R. BOTT , Marguerite A. Cervin , James T. Kellis, JR. , Joseph C. McAuliffe , Andrei Miasnikov , Caroline M. Peres , Christopher Lee Rife , Derek H. Wells , Walter Weyler , Gregory M. Whited
CPC分类号： C12N9/88 , C12P5/007 , C12Y402/03027
摘要： The present invention provides methods and compositions comprising at least one isoprene synthase enzyme with improved catalytic activity and/or solubility. In particular, the present invention provides variant plant isoprene synthases for increased isoprene production in microbial host cells. Biosynthetically produced isoprene of the present invention finds use in the manufacture of rubber and elastomers.
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8.发明授权公开(公告)号：US08153412B2
公开(公告)日：2012-04-10
申请号：US12264006
申请日：2008-11-03
申请人： Claudine Y. Chang , Clement Choy , Melodie Estabrook , Mansi Goyal , Thomas P. Graycar , Victoria E. Huang , Brian E. Jones , Marc Kolkman , Karsten M. Kragh , Chris Leeflang , Scott D. Power , Sandra W. Ramer , Andrew Shaw , Casper Vroemen , Walter Weyler
发明人： Claudine Y. Chang , Clement Choy , Melodie Estabrook , Mansi Goyal , Thomas P. Graycar , Victoria E. Huang , Brian E. Jones , Marc Kolkman , Karsten M. Kragh , Chris Leeflang , Scott D. Power , Sandra W. Ramer , Andrew Shaw , Casper Vroemen , Walter Weyler
IPC分类号： C12N9/28 , C12N9/26 , C12N9/24 , C12N1/20 , C12N15/00 , A23C17/00 , A23L1/28 , C11D3/02 , C12D3/00 , C12D3/386 , C07H21/04 , C07K1/00
CPC分类号： C11D3/386 , C11D3/38681 , C12N9/2417
摘要： Variants of Bacillus sp. TS-23 strain alpha-amylases exhibit improved enzymatic performance, including increased themostability, reduced calcium dependence, increased washing/cleaning performance, and baking ability. Compositions comprising these variants are useful in methods of starch processing, starch liquefaction, fermatation, starch saccharification, cleaning, laundrying, textile desizing, baking, and biofilm removal.
摘要翻译： 芽孢杆菌的变种 TS-23菌株α-淀粉酶表现出改善的酶性能，包括增加其稳定性，降低钙依赖性，提高洗涤/清洁性能和烘烤能力。 包含这些变体的组合物可用于淀粉加工，淀粉液化，粉化，淀粉糖化，清洗，洗衣，纺织品退浆，烘烤和生物膜除去的方法。
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9.发明申请Compositions and Uses for an Alpha-Amylase Polypeptide of Bacillus Species 195 失效芽孢杆菌物种的α-淀粉酶多肽的组成和用途195公开(公告)号：US20100035787A1
公开(公告)日：2010-02-11
申请号：US12519879
申请日：2007-12-06
申请人： Neelam S. Amin , Melodie Estabrook , Brian E. Jones , Marc Kolkman , Casper Vroemen , Walter Weyler
发明人： Neelam S. Amin , Melodie Estabrook , Brian E. Jones , Marc Kolkman , Casper Vroemen , Walter Weyler
IPC分类号： C11D3/386 , C12N15/56 , C12N9/24 , C12N15/75 , C12N1/21 , C11D7/42 , C12S9/00 , C12N15/70 , C12N15/76
CPC分类号： C12N9/2417
摘要： Disclosed herein are compositions comprising an alpha-amylase enzyme obtained from Bacillus sp. no. 195, and methods of using the enzyme to clean surfaces and textiles. Also disclosed are variants of the enzyme with different signal sequences.
摘要翻译： 本文公开了包含从芽孢杆菌属（Bacillus sp。）获得的α-淀粉酶的组合物。 没有。 195，以及使用酶清洁表面和纺织品的方法。 还公开了具有不同信号序列的酶的变体。
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公开(公告)号：US20080145353A1
公开(公告)日：2008-06-19
申请号：US10581014
申请日：2004-12-03
申请人： Neelam S. Amin , Matthew G. Boston , Richard R. Bott , Marguerite A. Cervin , Edward M. Concar , Marc E. Gustwiller , Brain E. Jones , Klaus Liebeton , Gregory S. Miracle , Hiroshi Oh , Ayrookaran J. Poulose , Sandra W. Ramer , Jeffrey J. Scheibel , Walter Weyler , Gregory M. Whited
发明人： Neelam S. Amin , Matthew G. Boston , Richard R. Bott , Marguerite A. Cervin , Edward M. Concar , Marc E. Gustwiller , Brain E. Jones , Klaus Liebeton , Gregory S. Miracle , Hiroshi Oh , Ayrookaran J. Poulose , Sandra W. Ramer , Jeffrey J. Scheibel , Walter Weyler , Gregory M. Whited
CPC分类号： A01N63/00 , C11D3/38636 , C12N9/16 , C12N9/50 , C12N9/52
摘要： The present invention provides methods and compositions comprising at least one perhydrolase enzyme for cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions for generation of peracids. The present invention finds particular use in applications involving cleaning, bleaching and disinfecting.
摘要翻译： 本发明提供包含至少一种用于清洁和其它应用的过水解酶的方法和组合物。 在一些特别优选的实施方案中，本发明提供了用于产生过酸的方法和组合物。 本发明特别用于涉及清洗，漂白和消毒的应用中。
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