公开(公告)号：US07617898B2

公开(公告)日：2009-11-17

申请号：US12155427

申请日：2008-06-04

申请人： Loo Weng Leong

发明人： Loo Weng Leong

IPC分类号： B62D25/10

CPC分类号： B60R21/38

摘要： A system configured to lift a hood includes: a first mounting member, provided on a rear part of the hood; a second mounting member, provided on a body of the vehicle body; a connecting member, including: a first portion, supported on a first position of the first mounting member; and a second portion, supported on the second mounting member; a detector, configured to detect a collision of the vehicle body with an object; an actuator, configured to lift the rear part of the hood when the detector detects the collision; and a stopper, configured to restrict a rising amount of the hood, the stopper including: a third portion, s supported on the first mounting member, the third portion being located in a rear side of the first portion; and a fourth portion, supported on the second mounting member coaxially with the second portion.

摘要翻译： 构造成提升罩的系统包括：第一安装构件，设置在罩的后部; 第二安装构件，设置在车体的主体上; 连接构件，包括：支撑在所述第一安装构件的第一位置上的第一部分; 以及第二部分，其支撑在所述第二安装构件上; 检测器，被配置为检测车身与物体的碰撞; 致动器，构造成当检测器检测到碰撞时提升罩的后部; 以及止动件，其构造成限制所述罩的上升量，所述止动件包括：支撑在所述第一安装构件上的第三部分，所述第三部分位于所述第一部分的后侧; 以及与第二部分同轴地支撑在第二安装构件上的第四部分。

公开(公告)号：US07501715B2

公开(公告)日：2009-03-10

申请号：US11142025

申请日：2005-06-01

申请人： Sakda Saeueng ,  Mingchun Xu ,  Weng Leong Hon

发明人： Sakda Saeueng ,  Mingchun Xu ,  Weng Leong Hon

IPC分类号： H02J1/00

CPC分类号： H02M3/33561 ,  H02M3/33592 ,  Y02B70/1475 ,  Y10T307/43

摘要： A multi-output DC-DC converter is advantageous over the conventional multi-output DC-DC converter in terms of increased power efficiency and power density. The inventive multi-output DC-DC converter is characterized by that the rectifying circuit located at the output stage of the DC-DC converter is implemented by a pair of self-driven synchronous rectifier transistors that can prevent a reverse current from flowing through the switch elements of the DC-DC converter. Also, a plurality of post voltage regulators are tapped to a secondary winding of the DC-DC converter, in which each post voltage regulator includes a voltage level shifter circuit for allowing gate drivers to impose a small amount of dead time on the control pulse signals for driving the internal transistor switches to minimize the dead time loss occurred during power conversion operation.

摘要翻译： 在提高功率效率和功率密度方面，多输出DC-DC转换器比传统的多输出DC-DC转换器更有优势。 本发明的多输出DC-DC转换器的特征在于，位于DC-DC转换器的输出级的整流电路由一对自驱动同步整流晶体管实现，其可以防止反向电流流过开关 DC-DC转换器的元件。 此外，多个后稳压器被抽头到DC-DC转换器的次级绕组，其中每个后稳压器包括电压电平移位器电路，用于允许栅极驱动器在控制脉冲信号上施加少量死区时间 用于驱动内部晶体管开关以最小化电力转换操作期间发生的死区时间损失。

公开(公告)号：US20090004741A1

公开(公告)日：2009-01-01

申请号：US12137450

申请日：2008-06-11

申请人： Jun Wang ,  Hai-Quan Mao ,  Kam Weng Leong

发明人： Jun Wang ,  Hai-Quan Mao ,  Kam Weng Leong

IPC分类号： C12N15/87

CPC分类号： C08L85/02 ,  A61K47/59 ,  C08G79/02

摘要： The present invention is directed to a series of new polycationic biodegradable polyphosphoramidates. Process for making the polymers, compositions containing these polymers and bioactive ligands to enhance the cellular uptake ad intracellular trafficking, articles and methods for delivery of drugs and genes using these polymers are described. A gene delivery system based on these polymers is prepared by complex coacervation of nucleic acid (DNA or RNA) with polymers. Targeting ligands and molecules that could facilitate gene transfer can be conjugated to polymers to achieve selective and enhanced gene delivery. The current invention also provides a complex composition with buffering capacity.

公开(公告)号：US07345138B2

公开(公告)日：2008-03-18

申请号：US10499898

申请日：2002-05-14

申请人： Jun Wang ,  Hai-Quan Mao ,  Kam Weng Leong

发明人： Jun Wang ,  Hai-Quan Mao ,  Kam Weng Leong

IPC分类号： C08G63/68 ,  C08G79/02

CPC分类号： C08L85/02 ,  A61K9/1647 ,  A61K9/204 ,  A61K47/34 ,  A61K47/605 ,  A61K47/645 ,  A61K48/0041 ,  C08G79/04 ,  C12N15/87

摘要： The present invention is directed to a biodegradable system for the controlled release of bioactive substances. This system comprises novel biodegradable and biocompatible polyphosphoesters that carry positive charges. Process for making these polyphosphoesters, compositions containing these polyphosphoesters and biologically active substances, articles and methods for delivery of drugs and genes using this system are described. A controlled gene delivery system based on these polyphosphoesters is prepared by complex coacervation of nucleic acid (DNA or RNA) with polymers. The release rates can be manipulated by adjusting the charge ratios of polyphosphoesters to nucleic acids. This gene delivery system yields a higher gene expression in muscle when injected intramuscularly.

摘要翻译： 本发明涉及用于控制释放生物活性物质的可生物降解的系统。 该系统包含携带正电荷的新型生物可降解和生物相容性聚磷酸酯。 描述了制备这些聚磷酸酯的方法，含有这些聚磷酸酯和生物活性物质的组合物，使用该系统递送药物和基因的制品和方法。 通过核酸（DNA或RNA）与聚合物的复合凝聚来制备基于这些多聚磷酸酯的受控基因递送系统。 可以通过调节多聚磷酸酯与核酸的电荷比来操纵释放速率。 当肌内注射时，该基因递送系统在肌肉中产生较高的基因表达。

公开(公告)号：US20070255198A1

公开(公告)日：2007-11-01

申请号：US11663056

申请日：2005-09-12

申请人： Weng Leong ,  Leigh Canham

发明人： Weng Leong ,  Leigh Canham

IPC分类号： A61M5/14

CPC分类号： A61M5/32

摘要： The present invention relates to a substance delivery device comprising: (a) an electronic component, (b) a carrier component, and (c) a beneficial substance, the electronic component comprising: (i) a timer means for generating a carrier activation electrical signal that is time dependent; (ii) an electronic carrier activation means for releasing the beneficial substance in response to the carrier activation electrical signal; (iii) a power supply; and (iv) a substance delivery device activation means, for activating the device, having a construction such that once the substance delivery device is activated the electronic carrier activation means releases the beneficial substance in response to the carrier activation electrical signal. The substance delivery device is of particular value in the treatment of circadian, infradian, or ultradian cycle conditions.

摘要翻译： 本发明涉及一种物质输送装置，包括：（a）电子部件，（b）载体部件和（c）有益物质，所述电子部件包括：（i）定时器装置，用于产生载体激活电 信号是时间依赖的; （ii）电子载体激活装置，用于响应于载体激活电信号释放有益物质; （iii）电源; 以及（iv）用于启动装置的物质输送装置激活装置，具有这样的结构，使得一旦物质输送装置被激活，电子载体激活装置响应于载体激活电信号释放有益物质。 物质输送装置在治疗昼夜节律，昼夜节律或超声周期条件方面具有特别的价值。

公开(公告)号：US08980458B2

公开(公告)日：2015-03-17

申请号：US13292148

申请日：2011-11-09

申请人： Hideki Honjo ,  Weng Leong Loo ,  Masanori Inagaki ,  Seiichi Takasaki ,  Takanori Yamamoto ,  Takeshi Fujii

发明人： Hideki Honjo ,  Weng Leong Loo ,  Masanori Inagaki ,  Seiichi Takasaki ,  Takanori Yamamoto ,  Takeshi Fujii

IPC分类号： H01M2/10 ,  B60K1/04 ,  H01M10/0525

CPC分类号： H01M2/1083 ,  B60K1/04 ,  B60K2001/0438 ,  H01M10/0525 ,  Y02E60/122 ,  Y02T10/7011

摘要： A battery casing for receiving a battery for driving an electric vehicle, including: a tray member made from a resin and supporting the battery; a support member provided under a lower face of the tray member and supporting the tray member from a bottom thereof; a standing wall provided so as to stand in the tray member; and a sheet metal tray member made from a sheet metal and placed on the tray member. The sheet metal tray member includes a plurality of sheet metal recesses that receive the battery and a sheet metal flange placed on an upper face of the standing wall. The standing wall includes a through hole formed through the standing wall in a standing direction of the standing wall. The support member and the sheet metal flange are fastened to the tray member by a sheet metal fastening member provided through the through hole.

摘要翻译： 一种用于接收用于驱动电动车辆的电池的电池壳体，包括：由树脂制成并支撑电池的托盘构件; 支撑构件，其设置在所述托盘构件的下表面下方并从其底部支撑所述托盘构件; 设置成立在所述托盘构件中的立壁; 以及由金属板制成并放置在托盘构件上的金属板托盘构件。 金属板托盘构件包括容纳电池的多个金属板凹部和设置在立壁的上表面上的金属板凸缘。 站立壁包括在站立壁的竖立方向上穿过竖立壁形成的通孔。 支撑构件和金属板凸缘通过贯通孔设置的金属片紧固构件固定在托盘构件上。

公开(公告)号：US20140230038A1

公开(公告)日：2014-08-14

申请号：US14345878

申请日：2012-02-16

申请人： Chik Weng Leong ,  Chee Ho Lau ,  Yuen Len Kong ,  Tau Wei Phang ,  Hoon Sin Cheong

发明人： Chik Weng Leong ,  Chee Ho Lau ,  Yuen Len Kong ,  Tau Wei Phang ,  Hoon Sin Cheong

IPC分类号： H04L29/06

CPC分类号： H04L63/08 ,  H04L9/3215 ,  H04L63/0853 ,  H04L63/0876 ,  H04L63/18 ,  H04W12/00 ,  H04W12/06 ,  H04W12/08

摘要： A novel method of dealing with the problem of phishing, pharming, key-logging and man-in-the-middle attacks on internet-based applications which require the application (3) (such as an internet banking website) by the simple transmission of a command via the internet to allow access to the internet-based application (3) whenever the user wishes to access the application, and by transmitting a command via the internet to deny access to the internet-based application at all other times, to present unauthorized access by any unscrupulous parties.

摘要翻译： 一种处理因特网应用程序的网络钓鱼，制药，密钥记录和中间人攻击的问题的新方法，需要通过简单的传输（3）（3）（例如网上银行网站） 每当用户希望访问应用时，通过因特网允许访问基于因特网的应用（3）的命令，并且通过经由互联网发送命令以拒绝在所有其他时间访问基于因特网的应用，以呈现 任何不道德的政党未经授权进入。

公开(公告)号：US20080176959A1

公开(公告)日：2008-07-24

申请号：US12016183

申请日：2008-01-17

申请人： Jun WANG ,  Hai-Quan MAO ,  Kam Weng LEONG

发明人： Jun WANG ,  Hai-Quan MAO ,  Kam Weng LEONG

IPC分类号： A61K47/48

CPC分类号： C08L85/02 ,  A61K9/1647 ,  A61K9/204 ,  A61K47/34 ,  A61K47/605 ,  A61K47/645 ,  A61K48/0041 ,  C08G79/04 ,  C12N15/87

摘要： The present invention is directed to a biodegradable system for the controlled release of bioactive substances. This system comprises novel biodegradable and biocompatible polyphosphoesters that carry positive charges. Process for making these polyphosphoesters, compositions containing these polyphosphoesters and biologically active substances, articles and methods for delivery of drugs and genes using this system are described. A controlled gene delivery system based on these polyphosphoesters is prepared by complex coacervation of nucleic acid (DNA or RNA) with polymers. The release rates can be manipulated by adjusting the charge ratios of polyphosphoesters to nucleic acids. This gene delivery system yields a higher gene expression in muscle when injected intramuscularly.

摘要翻译： 本发明涉及用于控制释放生物活性物质的可生物降解的系统。 该系统包含携带正电荷的新型生物可降解和生物相容性聚磷酸酯。 描述了制备这些聚磷酸酯的方法，含有这些聚磷酸酯和生物活性物质的组合物，使用该系统递送药物和基因的制品和方法。 通过核酸（DNA或RNA）与聚合物的复合凝聚来制备基于这些多聚磷酸酯的受控基因递送系统。 可以通过调节多聚磷酸酯与核酸的电荷比来操纵释放速率。 当肌内注射时，该基因递送系统在肌肉中产生较高的基因表达。

公开(公告)号：US20060236519A1

公开(公告)日：2006-10-26

申请号：US11289648

申请日：2005-11-30

申请人： Song Ser ,  Weng Leong

发明人： Song Ser ,  Weng Leong

IPC分类号： B21D53/00 ,  B21D22/00 ,  B21D31/00

CPC分类号： B21D22/02 ,  B21D28/26 ,  Y10T29/49837 ,  Y10T29/5116

摘要： A method of forming blind holes in a sheet material is provided. The method includes forming a recessed segment in the sheet material, stamping the recessed segment between a tapered punch and a pad to form a blind hole having a sealed end and a sidewall, wherein the pad includes a profiling pin that is enclosed by the sealed end and the sidewall. The method further includes forming a material channel interposed between The tapered punch and a tapered die, and compressing the material channel to generate a material flow into the sidewall. The material channel may be narrowed to allow more material flow into the sidewall for additional sidewall thickness.

摘要翻译： 提供了一种在片材中形成盲孔的方法。 该方法包括在片材中形成凹陷部分，在锥形冲头和衬垫之间冲压凹陷部分以形成具有密封端部和侧壁的盲孔，其中衬垫包括由密封端部包围的型材销 和侧壁。 该方法还包括形成介于锥形冲头和锥形模之间的材料通道，并且压缩材料通道以产生进入侧壁的材料流。 材料通道可以变窄以允许更多的材料流入侧壁以获得额外的侧壁厚度。

公开(公告)号：US20060117928A1

公开(公告)日：2006-06-08

申请号：US11289638

申请日：2005-11-30

申请人： Song Ser ,  Weng Leong

发明人： Song Ser ,  Weng Leong

IPC分类号： B26D3/00

CPC分类号： H05K7/142 ,  B21K23/00 ,  B26F1/24 ,  B26F2210/08 ,  G11B33/02 ,  Y10T83/02

摘要： A method of forming blind holes in a sheet material is provided. The method includes punching the sheet material to define a hollow projection through the material and shearing a layer of material from the sheet material to form a sealed end over an opening of the hollow projection to form the blind hole. Further processing of the sheet material may be required depending on the desired diameter of the blind hole. Such further processing includes enlarging the hollow projection to a desired diameter of the blind hole and shearing the layer of material with several tapered pins with progressively decreasing diameters. As the sealed end formed is likely to have an uneven surface, the sealed end may be flattened to render a more refined appearance.

摘要翻译： 提供了一种在片材中形成盲孔的方法。 该方法包括冲压片材以限定通过该材料的中空突起并且从片材材料剪切材料层以在中空突起的开口上形成密封端以形成盲孔。 根据盲孔的期望直径，可能需要进一步处理片材。 这种进一步的处理包括将中空突起扩大到盲孔的期望直径，并用逐渐减小的直径的多个锥形销剪切材料层。 由于形成的密封端很可能具有不均匀的表面，所以密封端可以变平，从而形成更精致的外观。