公开(公告)号：US08508223B2

公开(公告)日：2013-08-13

申请号：US12751128

申请日：2010-03-31

申请人： Shinichi Kitane ,  Tokunori Kimura ,  Yuichi Yamashita

发明人： Shinichi Kitane ,  Tokunori Kimura ,  Yuichi Yamashita

IPC分类号： G01V3/00

CPC分类号： A61B5/055 ,  A61B5/0263 ,  A61B5/0456 ,  G01R33/5602 ,  G01R33/5635

摘要： A magnetic resonance imaging (MRI) apparatus acquires magnetic resonance (MR) data associated with a plurality of different delay times according to a pulse sequence in which a region-selective saturation pulse is first applied, a region-non-selective inversion recovery pulse is then applied, and then the magnetic resonance data is acquired, the delay time being defined as a period from the saturation pulse application time to the start of MR data acquisition. A plurality of blood flow image data respectively associated with the plurality of different delay times are created using the acquired MR data.

摘要翻译： 磁共振成像（MRI）装置根据首先施加区域选择性饱和脉冲的脉冲序列获取与多个不同延迟时间相关联的磁共振（MR）数据，区域 - 非选择性反转恢复脉冲为 然后应用，然后获取磁共振数据，延迟时间被定义为从饱和脉冲施加时间到开始MR数据采集的周期。 使用获取的MR数据创建分别与多个不同延迟时间相关联的多个血流图像数据。

公开(公告)号：US20120187948A1

公开(公告)日：2012-07-26

申请号：US13438141

申请日：2012-04-03

申请人： Yuichi YAMASHITA ,  Masao Yui

发明人： Yuichi YAMASHITA ,  Masao Yui

IPC分类号： G01R33/34

摘要： A magnetic resonance imaging apparatus according to an embodiment includes a first acquiring unit, a second acquiring unit, and a combining unit. The first acquiring unit is configured to acquire data by executing a pulse sequence based on a first radio-frequency pulse transmission condition. The second acquiring unit is configured to acquire data by executing a pulse sequence based on a second radio-frequency pulse transmission condition that is different from the first radio-frequency pulse transmission condition. The combining unit is configured to perform a combining process either on the data acquired by the first acquiring unit and the data acquired by the second acquiring unit or on data obtained by reconstructing the data acquired by the first acquiring unit and data obtained by reconstructing the data acquired by the second acquiring unit.

摘要翻译： 根据实施例的磁共振成像装置包括第一获取单元，第二获取单元和组合单元。 第一获取单元被配置为通过基于第一射频脉冲发送条件执行脉冲序列来获取数据。 第二获取单元被配置为通过基于与第一射频脉冲发送条件不同的第二射频脉冲发送条件执行脉冲序列来获取数据。 组合单元被配置为对由第一获取单元获取的数据和由第二获取单元获取的数据执行组合处理，或者通过重建由第一获取单元获取的数据而获得的数据和通过重建数据获得的数据 由第二收购单位收购。

公开(公告)号：US20110074417A1

公开(公告)日：2011-03-31

申请号：US12751128

申请日：2010-03-31

申请人： Shinichi Kitane ,  Tokunori Kimura ,  Yuichi Yamashita

发明人： Shinichi Kitane ,  Tokunori Kimura ,  Yuichi Yamashita

IPC分类号： G01R33/48

CPC分类号： A61B5/055 ,  A61B5/0263 ,  A61B5/0456 ,  G01R33/5602 ,  G01R33/5635

摘要： To provide a magnetic resonance imaging apparatus capable of acquiring a non-contrast MRA image in which a background signal is sufficiently suppressed in a shorter time. A magnetic resonance imaging apparatus has: a data acquiring unit that acquires a plurality of pieces of magnetic resonance data associated with a plurality of different delay times according to a pulse sequence in which a region-selective saturation pulse is first applied, a region-non-selective inversion recovery pulse is then applied, and then the magnetic resonance data is acquired, the delay time being defined as a period from a time of application of the saturation pulse to a time of start of acquisition of the magnetic resonance data; and a blood flow image creating unit that creates a plurality of pieces of blood flow image data associated with the plurality of different delay times using the magnetic resonance data.

摘要翻译： 提供一种能够获取在较短时间内充分抑制背景信号的非造影MRA图像的磁共振成像装置。 磁共振成像装置具有：数据获取单元，其根据首先施加区域选择性饱和脉冲的脉冲序列获取与多个不同延迟时间相关联的多个磁共振数据，区域非 然后施加选择性反转恢复脉冲，然后获取磁共振数据，延迟时间被定义为从施加饱和脉冲的时间到开始获取磁共振数据的时间的周期; 以及血流图像生成单元，其使用所述磁共振数据来生成与所述多个不同延迟时间相关联的多个血流图像数据。

公开(公告)号：US20110074416A1

公开(公告)日：2011-03-31

申请号：US12722875

申请日：2010-03-12

申请人： Yuichi YAMASHITA ,  Nobuyasu Ichinose ,  Shinichi Kitane

发明人： Yuichi YAMASHITA ,  Nobuyasu Ichinose ,  Shinichi Kitane

IPC分类号： G01R33/48

CPC分类号： G01R33/28 ,  A61B5/0042 ,  A61B5/055 ,  A61B5/7285 ,  G01R33/54 ,  G01R33/5602 ,  G01R33/56333 ,  G06T7/0012

摘要： A magnetic resonance imaging apparatus includes a magnetic resonance data acquisition unit and a cerebrospinal fluid image data generation unit.The magnetic resonance data acquisition unit consecutively acquires a plurality of magnetic resonance data for generating a plurality of cerebrospinal fluid image data, each corresponding to a different data acquisition time, after a labeling pulse is applied.The cerebrospinal fluid image data generation unit generates the plurality of cerebrospinal fluid image data based on the plurality of magnetic resonance data.

摘要翻译： 磁共振成像装置包括磁共振数据获取单元和脑脊液图像数据生成单元。 在施加标记脉冲之后，磁共振数据获取单元连续地获取用于产生多个脑脊液图像数据的多个磁共振数据，每个脑脊液图像数据对应于不同的数据获取时间。 脑脊液图像数据生成单元基于多个磁共振数据生成多个脑脊液图像数据。

公开(公告)号：US20050171440A1

公开(公告)日：2005-08-04

申请号：US11037338

申请日：2005-01-19

申请人： Atsushi Maki ,  Hideaki Koizumi ,  Fumio Kawaguchi ,  Yuichi Yamashita ,  Yoshitoshi Ito

发明人： Atsushi Maki ,  Hideaki Koizumi ,  Fumio Kawaguchi ,  Yuichi Yamashita ,  Yoshitoshi Ito

IPC分类号： A61B5/00 ,  A61B5/05 ,  A61B5/055 ,  A61B5/18 ,  A61B6/00 ,  A61B6/03

CPC分类号： A61B5/0059 ,  A61B5/0042 ,  A61B5/055 ,  A61B5/14552 ,  A61B5/14553 ,  A61B5/18 ,  A61B5/6814 ,  A61B5/7207 ,  A61B5/7228 ,  A61B6/03 ,  A61B6/507 ,  A61B2562/0219 ,  A61B2562/0233 ,  A61B2562/046

摘要： In an optical measurement system and imaging method adapted to measure in vivo information in a living body without harming the living body, light rays of a plurality of wavelengths which are modulated in intensity with a plurality of different frequencies are irradiated on a plurality of irradiation positions on the surface of a living body, and time-variable changes in living body transmitting light intensity levels corresponding to the respective wavelengths and the respective irradiation positions are measured at different positions on the surface of the living body. Light is utilized to image the results of the measurements, in which the measuring time is shortened by estimating fluctuation attributable to the living body, and the presence or absence of a change in measured signal can be decided easily by displaying an estimation signal and a measured signal at a time.

公开(公告)号：US06640133B2

公开(公告)日：2003-10-28

申请号：US09849409

申请日：2001-05-07

申请人： Yuichi Yamashita ,  Atsushi Maki ,  Hideaki Koizumi

发明人： Yuichi Yamashita ,  Atsushi Maki ,  Hideaki Koizumi

IPC分类号： A61B505

CPC分类号： A61B5/0059 ,  A61B5/055 ,  A61B5/14546 ,  A61B5/14552 ,  A61B5/14553 ,  A61B5/18 ,  A61B5/6814 ,  A61B6/03 ,  A61B2562/0233 ,  A61B2562/0242 ,  A61B2562/046 ,  G01N21/35 ,  G01N21/4795

摘要： A control device for a living body including an input device having a launcher for launching light into the living body from at least one light incident position on a surface of the living body, a collector for collecting light obtained by causing the light incident from the light incident position to pass through the living body, at at least one light detection position on the surface of the living body, a detector for detecting an intensity of the transmitted light collected by the collector, an operator for determining a type of output signal, based on the intensity of the transmitted light, which has been detected by the detector and pre-stored reference data and for outputting a signal indicative thereof. External equipment is provided for using the signal outputted as an input signal and for executing a functional operation according to a type of the input signal.

摘要翻译： 一种生物体的控制装置，具有：输入装置，具有从生物体的表面上的至少一个光入射位置向所述生物体射出光的发射器，收集从所述光入射的光所得到的光的收集体 在生物体的表面上的至少一个光检测位置通过活体的入射位置，用于检测由收集器收集的透射光的强度的检测器，用于确定输出信号的类型的操作者 关于由检测器检测到的透射光的强度，以及预先存储的参考数据，并输出指示其的信号。 提供外部设备，用于使用作为输入信号输出的信号，并根据输入信号的类型执行功能操作。

公开(公告)号：US06282438B1

公开(公告)日：2001-08-28

申请号：US09203610

申请日：1998-12-02

申请人： Atsushi Maki ,  Hideaki Koizumi ,  Fumio Kawaguchi ,  Yuichi Yamashita ,  Yoshitoshi Ito

发明人： Atsushi Maki ,  Hideaki Koizumi ,  Fumio Kawaguchi ,  Yuichi Yamashita ,  Yoshitoshi Ito

IPC分类号： A61B600

CPC分类号： A61B5/0059 ,  A61B5/0042 ,  A61B5/055 ,  A61B5/14552 ,  A61B5/14553 ,  A61B5/18 ,  A61B5/6814 ,  A61B5/7207 ,  A61B5/7228 ,  A61B6/03 ,  A61B6/507 ,  A61B2562/0219 ,  A61B2562/0233 ,  A61B2562/046

摘要： Light rays of a plurality of wavelengths which are modulated in intensity with a plurality of different frequencies are irradiated on a plurality of irradiation positions on the surface of a living body, and time-variable changes in living body transmitting light intensity levels corresponding to the respective wavelengths and the respective irradiation positions are measured at different positions on the surface of the living body. After completion of the measurement or during the measurement, changes in concentration values of absorbers in the living body are determined from the living body transmitting light intensity levels of the plurality of wavelengths detected at the respective detection points and a measuring point is set on a perpendicular extending through an intermediate point between the incident point and each detection point so as to image a function of the living body. In living body optical measurement system and method, the measuring time is shortened by estimating fluctuation attributable to the living body, the presence or absence of a change in measured signal can be decided easily by displaying an estimation signal and a measured signal at a time, and a local change in. hemodynamic movement can be measured by detecting light rays transmitting through the interior of the living body by the two light detectors disposed at different two sites (equidistant from the light incident point) on a subject and by separating only the local change in hemodynamic movement from an overall change in hemodynamic movement in the living body in accordance with a logarithmic difference between the two detection signals.

摘要翻译： 以多个不同频率强度调制的多个波长的光线照射在生物体的表面上的多个照射位置上，并且生物体的时间变化透射与各个相对应的光强度水平 波长和各个照射位置在生物体的表面上的不同位置处被测量。 在测量完成之后或在测量期间，生物体中的吸收体的浓度值的变化是根据在各个检测点处检测到的多个波长的光强度水平来发射的，并且将测量点设定在垂直方向 延伸穿过入射点和每个检测点之间的中间点，以便对活体的功能进行成像。 在生物体光学测量系统和方法中，通过估计归因于生物体的波动来缩短测量时间，通过一次显示估计信号和测量信号可以容易地确定测量信号的变化是否存在， 并且可以通过检测设置在被摄体上不同的两个位置（等于光入射点的位置）的两个光检测器检测通过生物体的内部的光线，并且仅分离本地 根据两个检测信号之间的对数差异，从生物体的血液动力学运动的总体变化中改变血流动力学运动。

公开(公告)号：US5190039A

公开(公告)日：1993-03-02

申请号：US622607

申请日：1990-12-05

申请人： Hiroshi Takeuchi ,  Fumio Kawaguchi ,  Yuichi Yamashita ,  Kazuo Takeda ,  Yoshitoshi Ito ,  Yasuhiro Mitsui ,  Keiichi Nagai

发明人： Hiroshi Takeuchi ,  Fumio Kawaguchi ,  Yuichi Yamashita ,  Kazuo Takeda ,  Yoshitoshi Ito ,  Yasuhiro Mitsui ,  Keiichi Nagai

IPC分类号： A61B5/00 ,  A61B5/055 ,  A61B5/145 ,  G01R33/48

CPC分类号： A61B5/01 ,  A61B5/055 ,  A61B5/14539 ,  A61B5/14553 ,  G01R33/4804

摘要： An apparatus and a method for non-invasively measuring oxygen partial pressure in a living body in which light is thrown on a living body to be measured, the oxygen saturation of the living body is obtained from the light absorption spectrum or light scattering spectrum thereof, the temperature and/or pH of the living body is obtained from a nuclear magnetic resonance signal from the living body, and the oxygen partial pressure in the living body, useful for the diagnosis thereof, is determined on the basis of not only the oxygen saturation but also the temperature and/or pH of the living body.

摘要翻译： 从光的吸收光谱或光散射光谱获得生物体的氧饱和度的非活性测定生物体中的氧分压的装置和方法， 从生物体的核磁共振信号得到生物体的温度和/或pH值，根据生物体内的氧饱和度判定生物体的氧分压， 还有生物体的温度和/或pH值。

公开(公告)号：US08076935B2

公开(公告)日：2011-12-13

申请号：US12052274

申请日：2008-03-20

申请人： Shinichi Kitane ,  Mitsue Miyazaki ,  Yuichi Yamashita

发明人： Shinichi Kitane ,  Mitsue Miyazaki ,  Yuichi Yamashita

IPC分类号： G01V3/00

CPC分类号： G01R33/56 ,  G01R33/4828 ,  G01R33/5602 ,  G01R33/5607 ,  G01R33/5617

摘要： A magnetic resonance imaging apparatus includes an imaging condition setting unit and an image data acquisition unit. The imaging condition setting unit sets an imaging condition applying first and second suppression pulses of which at least ones of types, center frequencies and frequency bands are different from each other. The first and the second suppression pulses frequency-selectively suppress at least one of fat and silicone. The image data acquisition unit acquires image data according to the imaging condition.

摘要翻译： 磁共振成像设备包括成像条件设置单元和图像数据获取单元。 成像条件设置单元设置施加第一和第二抑制脉冲的成像条件，其中类型，中心频率和频带中的至少一些彼此不同。 第一和第二抑制脉冲频率选择性地抑制脂肪和硅酮中的至少一种。 图像数据获取单元根据成像条件获取图像数据。

公开(公告)号：US07774047B2

公开(公告)日：2010-08-10

申请号：US11371916

申请日：2006-03-10

申请人： Yuichi Yamashita ,  Atsushi Maki ,  Hideaki Koizumi

发明人： Yuichi Yamashita ,  Atsushi Maki ,  Hideaki Koizumi

IPC分类号： A61B6/00

CPC分类号： A61B5/14546 ,  A61B5/14553 ,  A61B2562/0233 ,  A61B2562/0242 ,  A61B2562/046 ,  G01N21/35 ,  G01N21/4795

摘要： An optical measurement instrument for a living body to measure dynamic change of blood of a brain includes light incident units for irradiating light on a head of a subject, a light detector for detecting a light irradiated from the light incident units and reflected within the subject, a signal processing unit for calculating a spacious distribution of signals from the subject to be measured from a signal detected by the light detector, and a display for displaying the spacious distribution of signals from the subject to be measured. Measurement points are arranged about a middle of the light incident units and the light detector, and the light incident units and the light detector are arranged such that the measurement points are arranged to form a lattice whose circumference is square.

摘要翻译： 用于测量大脑血液动态变化的生物体的光学测量仪器包括用于照射被检体头部的光入射单元，用于检测从光入射单元照射并在被检体内反射的光的光检测器， 信号处理单元，用于根据由光检测器检测到的信号计算来自待测对象的信号的宽敞分布;以及显示器，用于显示来自待测对象的信号的宽敞分布。 测量点围绕光入射单元和光检测器的中间布置，并且光​​入射单元和光检测器被布置成使得测量点被布置成形成圆周为正方形的格子。