公开(公告)号：US20100311958A1

公开(公告)日：2010-12-09

申请号：US12744797

申请日：2008-11-27

申请人： Takahiro Nishibu ,  Sohei Funaoka ,  Yuzo Yamaguchi

发明人： Takahiro Nishibu ,  Sohei Funaoka ,  Yuzo Yamaguchi

IPC分类号： C07H1/06 ,  B01J20/26

CPC分类号： C12N15/1006 ,  C12N15/111 ,  C12N15/113 ,  C12N2310/14 ,  C12N2310/141 ,  C12Q1/6813 ,  G01N33/5308 ,  C12Q2525/207

摘要： An object of the present invention is to provide a carrier which enables to obtain a small RNA in high yield yet in high purity, a simple method for obtaining a small RNA and/or a target nucleic acid of small RNA using the same, and a reagent and a kit comprising the above-described carrier.The present invention relates to (1) a carrier for obtaining a small RNA produced by introducing a polymerizable functional group or a chain transfer group to the surface of a core particle, mixing said particle with a polymerizable monomer, then promoting polymerization reaction to form a layer comprising a polymer compound on the surface of said particle, and immobilizing a physiologically active substance having affinity to a small RNA-binding protein on the surface of the particle; (2) a method for obtaining a small RNA, characterized by using the above-described carrier; (3) a reagent for obtaining a small RNA and/or a target nucleic acid of small RNA, comprising the above-described carrier; (4) a reagent kit for obtaining a small RNA and/or a target nucleic acid of small RNA, comprising said reagent; and (5) a method for obtaining a target nucleic acid of small RNA, characterized by using the above-described carrier.

摘要翻译： 本发明的目的是提供能够以高产率而高纯度获得小RNA的载体，使用该载体获得小RNA的RNA和/或靶核酸的简单方法，以及 试剂和包含上述载体的试剂盒。 本发明涉及（1）一种用于获得通过将可聚合官能团或链转移基团引入核心颗粒表面而获得的小RNA的载体，将所述颗粒与可聚合单体混合，然后促进聚合反应以形成 在所述颗粒的表面上包含聚合物化合物的层，并且将对小的RNA结合蛋白具有亲和力的生理活性物质固定在所述颗粒的表面上; （2）获得小RNA的方法，其特征在于使用上述载体; （3）包含上述载体的用于获得小RNA的小RNA和/或靶核酸的试剂; （4）包含所述试剂的用于获得小RNA的小RNA和/或靶核酸的试剂盒; 和（5）获得小RNA靶核酸的方法，其特征在于使用上述载体。

公开(公告)号：US5140482A

公开(公告)日：1992-08-18

申请号：US592914

申请日：1990-10-04

申请人： Hideyuki Kimura ,  Takuji Torii ,  Tsuyoshi Takahashi ,  Hiroshi Nishida ,  Kenji Mori ,  Yuzo Yamaguchi ,  Yokuo Saitoh ,  Kihachiro Tanaka ,  Shinobu Yoshida

发明人： Hideyuki Kimura ,  Takuji Torii ,  Tsuyoshi Takahashi ,  Hiroshi Nishida ,  Kenji Mori ,  Yuzo Yamaguchi ,  Yokuo Saitoh ,  Kihachiro Tanaka ,  Shinobu Yoshida

IPC分类号： G11B5/48

CPC分类号： G11B5/486

摘要： A head arm for use in a magnetic disk drive, comprising a guide arm disposed between a magnetic head and an actuator so as to transmit actuating force of the actuator to the magnetic head thereby guiding the magnetic head along a plane of a magnetic disk, a printed circuit fixed to the guide arm, and deflection compensating member for making the coefficients of thermal expansion of said guide arm and said printed circuit substantially equal to each other in at least the direction of seek of the head arm. No thermal deformation in an out-of-plane direction occurs on such a head arm regardless of any variation in the temperature of the environment in which the magnetic disk drive is installed. The head arm may also comprise a guide arm and a printed circuit formed of a moisture absorptive material and covered at all or part of its surfaces with a covering layer formed of a moisture resistive material not permeable to moisture. No deformation in an out-of-plane direction occurs on such a head arm regardless of any variation in the humidity of the environment in which the magnetic disk drive is installed. Therefore, the possibility of occurrence of off-track can be minimized.

摘要翻译： 一种用于磁盘驱动器的头臂，包括设置在磁头和致动器之间的引导臂，以将致动器的致动力传递到磁头，从而沿着磁盘的平面引导磁头， 固定到引导臂的印刷电路和用于使所述引导臂和所述印刷电路的热膨胀系数至少在头臂的寻找方向上彼此基本相等的偏转补偿构件。 在这种头臂上不发生面外方向的热变形，而不管安装有磁盘驱动器的环境的温度如何变化。 头臂还可以包括引导臂和由吸湿材料形成的印刷电路，并在其全部或部分表面上覆盖由不透湿水分的防潮材料形成的覆盖层。 在这种头臂上不发生面外方向的变形，而不管安装有磁盘驱动器的环境的湿度是否变化。 因此，可以使偏离轨迹的发生的可能性最小化。

公开(公告)号：US5136438A

公开(公告)日：1992-08-04

申请号：US550686

申请日：1990-07-10

申请人： Koosaku Wakatsuki ,  Shoji Suzuki ,  Noriaki Okamoto ,  Yuzo Yamaguchi ,  Katsuaki Kikuchi ,  Mikio Tokuyama ,  Yoshinori Takeuchi ,  Yoshihiko Miyake

发明人： Koosaku Wakatsuki ,  Shoji Suzuki ,  Noriaki Okamoto ,  Yuzo Yamaguchi ,  Katsuaki Kikuchi ,  Mikio Tokuyama ,  Yoshinori Takeuchi ,  Yoshihiko Miyake

IPC分类号： G11B5/48 ,  G11B5/54 ,  G11B5/55 ,  G11B5/60 ,  G11B21/12 ,  G11B21/21 ,  G11B25/04 ,  G11B33/14

CPC分类号： G11B5/6005 ,  G11B25/043 ,  G11B33/1446 ,  G11B5/4833 ,  G11B5/54 ,  G11B5/5565

摘要： A magnetic head device has a magnetic head slider by means of which information is recorded in and read from a magnetic recording medium. The magnetic head slider is supported by a supporting structure having an internal cavity, an opening formed in a portion of the structure where the magnetic head slider faces the magnetic recording medium and communicating with the internal cavity, and a gas passage through which the gas introduced into the internal cavity through the opening is discharged to the exterior of the internal cavity. With this arrangement, the pressure acting on the back surface of the magnetic head slider is adjusted to keep the slider afloat, while removing dust suspended in the gas around the recording medium and the supporting structure.

摘要翻译： 磁头装置具有磁头滑块，通过该磁头滑块将信息记录在磁记录介质中并从磁记录介质读取。 磁头滑块由具有内部空腔的支撑结构支撑，形成在结构的一部分中的磁头滑块面向磁记录介质并与内部空腔连通的开口以及气体引入的气体通道 通过开口进入内腔，排出到内腔外部。 通过这种布置，调节作用在磁头滑块的后表面上的压力，以保持滑块浮动，同时除去悬挂在记录介质和支撑结构周围的气体中的灰尘。

公开(公告)号：US4814906A

公开(公告)日：1989-03-21

申请号：US23241

申请日：1987-03-09

申请人： Shoji Suzuki ,  Toshinori Kazama ,  Hiroshi Daitou ,  Yoshinori Takeuchi ,  Yuzo Yamaguchi

发明人： Shoji Suzuki ,  Toshinori Kazama ,  Hiroshi Daitou ,  Yoshinori Takeuchi ,  Yuzo Yamaguchi

IPC分类号： G11B23/50 ,  G11B5/60 ,  G11B21/21 ,  G11B33/14

CPC分类号： G11B5/6005

摘要： A magnetic head slider for use with a magnetic recording medium has a bearing surface which opposes to the magnetic recording medium and generates a pneumatic bearing effect for floating the magnetic head slider above a surface of the magnetic recording medium. The bearing surface includes a tapered surface portion constituting an air entrance and a flat rail portion connected to the tapered surface portion. The magnetic head slider has vent holes formed in the flat rail portion penetrating through the magnetic head slider from the flat rail portions to an end surface of the slider opposite to the magnetic recording medium.

摘要翻译： 与磁记录介质一起使用的磁头滑块具有与磁记录介质相对的轴承表面，并产生用于将磁头滑块浮置在磁记录介质表面之上的气动轴承效果。 轴承面包括形成空气入口的锥形表面部分和连接到锥形表面部分的平坦轨道部分。 磁头滑动器具有形成在扁平轨道部分中的通气孔，其从平坦轨道部分穿过磁头滑块到与磁记录介质相对的滑块的端面。

公开(公告)号：US07336440B2

公开(公告)日：2008-02-26

申请号：US11387903

申请日：2006-03-24

申请人： Mikio Tokuyama ,  Hayato Shimizu ,  Satomitsu Imai ,  Shozo Saegusa ,  Masahiko Sega ,  Toshihisa Okazaki ,  Yuzo Yamaguchi

发明人： Mikio Tokuyama ,  Hayato Shimizu ,  Satomitsu Imai ,  Shozo Saegusa ,  Masahiko Sega ,  Toshihisa Okazaki ,  Yuzo Yamaguchi

IPC分类号： G11B33/14

CPC分类号： G11B33/148 ,  G11B25/043 ,  G11B33/08

摘要： A magnetic disc unit includes a rotating disc type magnetic disc having an outer periphery, and a carriage arm linked to a head support mechanism for a recording/reproducing head. A base has an outer periphery and mounts the rotating disc type magnetic disc and the carriage arm, and has a side wall with an inner wall surface having an opening for inserting the carriage arm. The inner wall surface of the side wall defines a shroud surrounding the outer periphery of the magnetic disc, except at the opening in the side wall where the shroud is projected inwardly so as to decrease an opening angle of the opening in the side wall. A gap between the outer periphery of the magnetic disc and the shroud is set in a range not less than 0.1 mm but not greater than 0.6 mm.

摘要翻译： 磁盘单元包括具有外周的旋转盘型磁盘和连接到用于记录/再现头的磁头支撑机构的滑架臂。 基座具有外周边并且安装旋转盘型磁盘和托架臂，并且具有侧壁，内壁表面具有用于插入托架臂的开口。 侧壁的内壁表面限定围绕磁盘的外周的护罩，除了侧壁中的开口处，护罩向内突出，以减小侧壁中开口的开口角度。 磁盘的外周与护罩之间的间隙设定在0.1mm以上且0.6mm以下的范围内。

公开(公告)号：US06665139B2

公开(公告)日：2003-12-16

申请号：US10022260

申请日：2001-12-20

申请人： Mikio Tokuyama ,  Hayato Shimizu ,  Satomitsu Imai ,  Shozo Saegusa ,  Masahiko Sega ,  Toshihisa Okazaki ,  Yuzo Yamaguchi ,  Masao Iwakura ,  Shigeo Nakamura ,  Kazuo Sakai ,  Shigenori Togashi ,  Masayuki Kaiho ,  Toshiaki Kobari

发明人： Mikio Tokuyama ,  Hayato Shimizu ,  Satomitsu Imai ,  Shozo Saegusa ,  Masahiko Sega ,  Toshihisa Okazaki ,  Yuzo Yamaguchi ,  Masao Iwakura ,  Shigeo Nakamura ,  Kazuo Sakai ,  Shigenori Togashi ,  Masayuki Kaiho ,  Toshiaki Kobari

IPC分类号： G11B3314

CPC分类号： G11B33/08 ,  G11B5/6005 ,  G11B25/043 ,  G11B33/1446

摘要： In a magnetic disc apparatus including a plurality of magnetic discs mounted on a spindle, arms supporting magnetic heads, a rotary actuator for the arms, and a housing having an arcuate-shaped shroud, the improvement wherein gaps between the shroud and the sides of outer peripheries of the magnetic discs are larger than 0.1 mm and less than 0.6 mm. An open space is located, downstream of the arms with respect to the air flow on surfaces of the magnetic discs, the open space being devoid of the shroud. An opening is provided in the shroud, upstream of the arms with respect to the air flow and having a greater width than a width of the gaps defined between the magnetic discs and the shroud, and a bypass channel is provided which communicates between the opening and open space.

摘要翻译： 在包括安装在主轴上的多个磁盘，支撑磁头的臂，用于臂的旋转致动器和具有弧形罩的壳体的磁盘装置中，改进之处在于罩与外侧之间的间隙 磁盘的周边大于0.1mm且小于0.6mm。 相对于磁盘表面上的气流，位于臂的下游的开放空间，开放空间没有护罩。 在护罩中，相对于空气流在臂的上游设置开口，并且具有比限定在磁盘和护罩之间的间隙的宽度更大的宽度，并且提供旁通通道，其在开口和 开放空间。

公开(公告)号：US5177652A

公开(公告)日：1993-01-05

申请号：US503909

申请日：1990-04-04

申请人： Yuzo Yamaguchi ,  Takayuki Munemoto

发明人： Yuzo Yamaguchi ,  Takayuki Munemoto

IPC分类号： G11B21/08 ,  G11B5/55 ,  G11B21/10

CPC分类号： G11B5/556

摘要： In a rotary-disk transducer position control apparatus and method in which positional information concerning a transducer relative to a rotary disk based on a signal is obtained from the transducer which is disposed in opposition to the rotary disk, a seek instruction is inputted through an input device so that a first transducer access mechanism is caused to make the transducer perform a seeking operation at a low speed with a large stroke in accordance with both the positional information and the seek instruction, and in order to make the transducer perform both a seeking operation and a following operation, a second transducer access mechanism is caused to drive the transducer at a high speed with a small stroke in accordance with the positional information and the seek instruction.

摘要翻译： 在旋转盘换能器位置控制装置和方法中，从与旋转盘相对设置的换能器获得关于基于信号的旋转盘的换能器的位置信息，通过输入来输入寻道指令 装置，使得第一换能器进入机构使得换能器根据位置信息和寻道指令两者以大的行程以低速执行寻道操作，并且为了使换能器执行寻道操作 并且进行以下操作，根据位置信息和寻道指令，使第二换能器进入机构以小行程高速驱动换能器。

公开(公告)号：US5128821A

公开(公告)日：1992-07-07

申请号：US529452

申请日：1990-05-29

申请人： Yoshinori Takeuchi ,  Yuzo Yamaguchi ,  Fumitaka Muranushi ,  Katsuyuki Tanaka ,  Kanji Kawakami ,  Hiroshi Daito ,  Tetsuo Masukawa

发明人： Yoshinori Takeuchi ,  Yuzo Yamaguchi ,  Fumitaka Muranushi ,  Katsuyuki Tanaka ,  Kanji Kawakami ,  Hiroshi Daito ,  Tetsuo Masukawa

IPC分类号： G11B21/21 ,  G11B5/60

CPC分类号： G11B5/6005

摘要： A flying head slider has gas bearing rails formed on a surface thereof disposed in opposed relation to a recording medium. The flying head slider flies at a microscopic distance above the recording medium by a pressure produced by a stream of gas resulted from the rotation of the recording medium. Each of the gas bearing rails comprises an inflow portion disposed at an inflow side of the gas stream so as to produce a pressure, an outflow portion disposed at an outflow side of the gas stream so as to produce a pressure, and a connective portion interconnecting the inflow portion and the outflow portion in a common plane. The connective portion serves to suppress an excessive compression of the gas, and achieves good damping characteristics.

摘要翻译： 飞头滑块具有形成在与记录介质相对的表面上的气体轴承轨道。 飞头滑块由记录介质的旋转产生的气体产生的压力在记录介质上方的微观距离处飞行。 每个气体支承轨道包括设置在气流的流入侧的流入部分，以便产生压力，设置在气流的出流侧的流出部分以产生压力，并且连接部分互连 流入部和流出部。 连接部用于抑制气体的过度压缩，并且实现良好的阻尼特性。

公开(公告)号：US5014144A

公开(公告)日：1991-05-07

申请号：US366612

申请日：1989-06-13

申请人： Taichi Sato ,  Yoshiharu Mouri ,  Kihachiro Tanaka ,  Yokuo Saitoh ,  Hiroshi Daito ,  Tetsuo Masukawa ,  Yoshinori Takeuchi ,  Yuzo Yamaguchi ,  Satomitsu Imai

发明人： Taichi Sato ,  Yoshiharu Mouri ,  Kihachiro Tanaka ,  Yokuo Saitoh ,  Hiroshi Daito ,  Tetsuo Masukawa ,  Yoshinori Takeuchi ,  Yuzo Yamaguchi ,  Satomitsu Imai

IPC分类号： G11B5/48

CPC分类号： G11B5/4826

摘要： An apparatus for supporting and reciprocating a magnetic head slider above a rotating magnetic disk comprises a carrying arm having a free end, a flexible base connected at one end thereof to the free end of the supporting arm, a pair of flexible fingers extending from the other end of the flexible base parallel to an axis of the carrying arm and defining therebetween a space, a traverse bar connecting two free ends of the fingers, and a flexible tongued member on which the magnetic head slider to be mounted, one end of the tongued member being connected to the traverse bar and the other end thereof extending into the space with gaps between the tongued member and the fingers and the base. A reduced part of a minimum cross-section is provided in each of the fingers. The reduced part is located between the one end of the tongued member and a center between the one end of the tongued member and the other end of the base.

摘要翻译： 用于在旋转磁盘上方支撑和往复运动磁头滑块的装置包括具有自由端的承载臂，在其一端连接到支撑臂的自由端的柔性基座，从另一个延伸的一对柔性指状物 柔性基座的平行于承载臂的轴线的端部并且在其间限定空间，连接指状物的两个自由端的横杆以及待安装的磁头滑块的柔性舌形构件，舌头的一端 构件连接到横动杆，并且其另一端延伸到舌形构件和指状物和基部之间的间隙中。 在每个手指中设置有最小横截面的缩小部分。 缩小部分位于舌部件的一端和舌部件的一端和基部的另一端之间的中心之间。

公开(公告)号：US4922356A

公开(公告)日：1990-05-01

申请号：US8259

申请日：1987-01-29

申请人： Yuzo Yamaguchi ,  Yoshinori Takeuchi ,  Yokuo Saitoh ,  Hiroshi Daito ,  Hiroyasu Nakajima ,  Yoshiakira Karakama ,  Yukimori Umakoshi ,  Kazunori Hori ,  Mikio Tokuyama

发明人： Yuzo Yamaguchi ,  Yoshinori Takeuchi ,  Yokuo Saitoh ,  Hiroshi Daito ,  Hiroyasu Nakajima ,  Yoshiakira Karakama ,  Yukimori Umakoshi ,  Kazunori Hori ,  Mikio Tokuyama

IPC分类号： G11B21/02 ,  G11B5/58 ,  G11B21/16 ,  G11B21/21

CPC分类号： G11B21/21 ,  G11B5/58

摘要： A transducer supporting apparatus is provided with a rigid structural support connected to a rigid arm portion and a flexible strucural support provided on the free end of the rigid structural support, the flexible structural support comprising two flexible fingers, a transverse frame connecting the two flexible fingers on the extending side thereof through steps, and a slider mounting portion having a tongue form which extends from this frame and is provided adjacent to the two flexible fingers and a slider loaded with a transducer being junctioned with the slider mounting portion. The flexible fingers are so configurated that the end thereof on the side of the rigid arm portion is brought nearer to the plane formed by the floating surface of the slider than the end thereof on the side of the slider mounting portion.

摘要翻译： 传感器支撑装置设置有刚性结构支撑件，其连接到刚性臂部分和设置在刚性结构支撑件的自由端上的柔性结构支撑件，柔性结构支撑件包括两个柔性指状物，连接两个柔性指状物的横向框架 在其延伸侧通过台阶，以及滑块安装部分，其具有从该框架延伸并且邻近两个柔性指状物设置的舌形，以及装载有与滑块安装部分连接的换能器的滑块。 柔性指状物被构造成使得其刚性臂部分侧的端部比滑动器安装部分侧的端部更靠近由滑块的浮动表面形成的平面。