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    SYSTEMS, DEVICES AND METHODS FOR ANALYTE SENSOR INSERTION
    3.
    发明申请
    SYSTEMS, DEVICES AND METHODS FOR ANALYTE SENSOR INSERTION 有权

    公开(公告)号：US20220007973A1

    公开(公告)日：2022-01-13

    申请号：US17357090

    申请日：2021-06-24

    申请人： ABBOTT DIABETES CARE INC.

    发明人： Vivek S. Rao ,  Louis G. Pace ,  Hyun Cho ,  Benjamin Jay Feldman ,  Yi Wang ,  Tuan Nguyen

    IPC分类号： A61B5/145 ,  A61B17/34 ,  A61B5/00

    摘要： Systems, devices and methods are provided for inserting at least a portion of an in vivo analyte sensor, such as a dermal sensor, for sensing an analyte level in a bodily fluid of a subject. An applicator is positioned against a skin surface and a force is applied to the applicator causing at least a portion of a sharp and an in vivo analyte sensor to be positioned in the body of the subject. In particular, disclosed herein are embodiments of applicators designed to prevent premature sharp withdrawal and/or reduce the likelihood of improper sensor insertion. Also disclosed are embodiments of applicators including sharp modules having an angled sharp which can be configured to create an insertion path for a sensor.

    Analyte Sensors and Sensing Methods for Detecting Creatinine
    4.
    发明申请
    Analyte Sensors and Sensing Methods for Detecting Creatinine 审中-公开

    公开(公告)号：US20200241015A1

    公开(公告)日：2020-07-30

    申请号：US16582583

    申请日：2019-09-25

    申请人： Abbott Diabetes Care Inc.

    发明人： Tianmei Ouyang ,  Benjamin J. Feldman ,  Hyun Cho

    IPC分类号： G01N33/70 ,  C12Q1/34 ,  C12Q1/00 ,  C12Q1/26 ,  G01N27/327

    摘要： Creatinine levels may be monitored as a measure of kidney function. Conventionally, blood and/or urine tests are used for this purpose. Analyte sensors capable of monitoring creatinine in vivo may comprise: a sensor tail comprising at least a first working electrode, a creatinine-responsive active area disposed upon a surface of the first working electrode, a first membrane that is permeable to creatinine and overcoats the creatinine-responsive active area, and an oxygen scavenger located upon the sensor tail in proximity to the creatinine-responsive active area. The creatinine-responsive active area comprises a first electron transfer agent, a first polymer, and an enzyme system comprising multiple enzymes, particularly creatinine amidohydrolase, creatine amidohydrolase, and sarcosine oxidase, that are capable of acting in concert to facilitate detection of creatinine. An oxidase enzyme may serve as the oxygen scavenger, particularly glucose oxidase when detecting creatinine in fluids also containing glucose.

    Analyte monitoring device and methods
    6.
    发明授权
    Analyte monitoring device and methods 有权

    公开(公告)号：US10285632B2

    公开(公告)日：2019-05-14

    申请号：US15659480

    申请日：2017-07-25

    申请人： ABBOTT DIABETES CARE INC.

    发明人： Udo Hoss ,  Benjamin J. Feldman ,  Zenghe Liu ,  Hyun Cho ,  Benjamin M. Rush

    IPC分类号： A61B5/1473 ,  A61B5/1468 ,  A61B5/145 ,  A61B5/00

    摘要： Method and system for determining real time analyte concentration including an analyte sensor having a portion in fluid contact with an interstitial fluid under a skin layer, an on-body electronics including a housing coupled to the analyte sensor and configured for positioning on the skin layer, the on-body electronics housing including a plurality of electrical contacts, on the housing; and a data analysis unit having a data analysis unit housing and a plurality of probes, on the housing. Each of the probes configured to electrically couple to a respective electrical contact when the data analysis unit is positioned in physical contact with the on-body electronics. The one or more signals on the probes correspond to one or more of a substantially real time monitored analyte concentration level (MACL), MACL over a predetermined time period, or a rate of change of the MACL, or combinations thereof, are provided.

    ADAPTOR FOR ON-BODY ANALYTE MONITORING SYSTEM
    8.
    发明申请
    ADAPTOR FOR ON-BODY ANALYTE MONITORING SYSTEM 审中-公开

    公开(公告)号：US20180289295A1

    公开(公告)日：2018-10-11

    申请号：US15945636

    申请日：2018-04-04

    申请人： ABBOTT DIABETES CARE INC.

    发明人： Udo Hoss ,  Craig W. Sharp ,  Hyun Cho ,  Todd Winkler ,  Paul Legg

    IPC分类号： A61B5/145

    摘要： An analyte monitoring system comprising: an on-body housing; an analyte sensor coupled to the housing; an electrical output interface disposed on an outer surface of the housing; and a removable adaptor coupled to the housing. In one embodiment, a portion of the analyte sensor extends from the housing for implantation into a patient's body. The electrical output interface is electrically coupled to the analyte sensor. The removable adaptor is mechanically coupled to the housing and electrically coupled to the electrical output interface. The removable adaptor serves as a data conduit between the analyte sensor and a remote device.

    Analyte monitoring devices
    10.
    发明授权
    Analyte monitoring devices 有权
    分析物监测装置

    公开(公告)号：US09232916B2

    公开(公告)日：2016-01-12

    申请号：US14595147

    申请日：2015-01-12

    申请人： Abbott Diabetes Care Inc.

    发明人： Fei Mao ,  Hyun Cho

    IPC分类号： A61B5/05 ,  A61B5/1486 ,  C12Q1/00 ,  A61B5/145 ,  A61B5/00 ,  A61B5/1473

    CPC分类号： A61B5/14865 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/6846 ,  C12Q1/002 ,  C12Q1/004 ,  C12Q1/006

    摘要： Novel membranes comprising various polymers containing heterocyclic nitrogen groups are described. These membranes are usefully employed in electrochemical sensors, such as amperometric biosensors. More particularly, these membranes effectively regulate a flux of analyte to a measurement electrode in an electrochemical sensor, thereby improving the functioning of the electrochemical sensor over a significant range of analyte concentrations. Electrochemical sensors equipped with such membranes are also described.

    摘要翻译： 描述了包含含有杂环氮基团的各种聚合物的新型膜。 这些膜可用于电化学传感器，如电流分析生物传感器。 更具体地，这些膜有效地将分析物的通量调节到电化学传感器中的测量电极，由此在显着的分析物浓度范围内改善了电化学传感器的功能。 还描述了配备有这种膜的电化学传感器。