公开(公告)号：US20230011549A1

公开(公告)日：2023-01-12

申请号：US17372093

申请日：2021-07-09

Applicant: AGILENT TECHNOLOGIES, INC.

Inventor： Shaouhan HU ,  Daniela Loraing ,  Olga Schikurski ,  Sascha Lege ,  Stephan Buckenmaier

IPC: B42F7/02

Abstract: In some examples, an organizer may include a plurality of inserts. At least one insert of the plurality of inserts may include at least a front panel and an opposite back panel that form the at least one insert, and at least one instrument component disposed hi the at least one insert. The organizer may further include a binding mechanism that attaches the plurality of inserts.

公开(公告)号：US20220065827A1

公开(公告)日：2022-03-03

申请号：US17446096

申请日：2021-08-26

Applicant: Agilent Technologies, Inc.

Inventor： Konstantin Shoykhet ,  Stephan Buckenmaier

IPC: G01N30/46 ,  G01N30/32 ,  G01N30/14

Abstract: A multi-dimensional liquid chromatography system includes first and second liquid chromatography systems. The first system is configured for providing a first chromatographic separation of a sample fluid comprised in a first mobile phase and to provide a first effluent including at least a portion of the separated sample fluid. The second system is configured for providing a second chromatographic separation of at least a portion of the first effluent comprised in a second mobile phase. A control unit is configured to operate the first liquid chromatography system by maintaining a first flow rate of the first mobile phase substantially constant during the first chromatographic separation, and to operate the second liquid chromatography system during the second chromatographic separation according to a control value different from the second flow rate, so that a variation in the control value can lead to a variation in the second flow rate.

公开(公告)号：US11808742B2

公开(公告)日：2023-11-07

申请号：US17446096

申请日：2021-08-26

Applicant: Agilent Technologies, Inc.

Inventor： Konstantin Shoykhet ,  Stephan Buckenmaier

IPC: G01N30/46 ,  G01N30/14 ,  G01N30/32 ,  G01N30/02

CPC classification number: G01N30/46 ,  G01N30/14 ,  G01N30/32 ,  G01N2030/027 ,  G01N2030/324 ,  G01N2030/326

Abstract: A multi-dimensional liquid chromatography system includes first and second liquid chromatography systems. The first system is configured for providing a first chromatographic separation of a sample fluid comprised in a first mobile phase and to provide a first effluent including at least a portion of the separated sample fluid. The second system is configured for providing a second chromatographic separation of at least a portion of the first effluent comprised in a second mobile phase. A control unit is configured to operate the first liquid chromatography system by maintaining a first flow rate of the first mobile phase substantially constant during the first chromatographic separation, and to operate the second liquid chromatography system during the second chromatographic separation according to a control value different from the second flow rate, so that a variation in the control value can lead to a variation in the second flow rate.

公开(公告)号：US20220283129A1

公开(公告)日：2022-09-08

申请号：US17631924

申请日：2020-07-30

Applicant: Agilent Technologies, Inc.

Inventor： Dwight Robert Stoll ,  Konstantin Shoykhet ,  Thomas Ortmann ,  Stephan Buckenmaier ,  Sascha Lege

IPC: G01N30/46

Abstract: A fluid processing apparatus includes a first fluid processing unit and a second fluid processing unit. A fluid unit is fluidically coupled to the first fluid processing unit and includes a first buffering unit configured for buffering fluid, and/or a mask flow source configured for providing a mask fluid or a flow thereof. A first coupling point is fluidically coupled between the first fluid processing unit and the fluid unit. A modulation unit is configured, selectively, for withdrawing fluid from the first coupling point, or for transferring withdrawn fluid into the second fluid processing unit. The apparatus may be utilized for chromatography.

公开(公告)号：US20160334031A1

公开(公告)日：2016-11-17

申请号：US14975342

申请日：2015-12-18

Applicant: Agilent Technologies, Inc.

Inventor： Konstantin Shoykhet ,  Klaus Witt ,  Stephan Buckenmaier ,  Dwight Stoll

IPC: F16K99/00 ,  B01D15/10 ,  G01N27/447 ,  B01L3/00

CPC classification number: F16K99/0028 ,  B01D15/10 ,  B01D15/1878 ,  B01D15/40 ,  B01L3/50273 ,  B01L2400/0475 ,  F16K2099/0084 ,  G01N27/44791 ,  G01N30/32 ,  G01N30/465 ,  G01N2030/202 ,  G01N2030/328

Abstract: A fluid processing device (10) for processing fluid, wherein the fluid processing device (10) comprises a first fluid drive unit (20) configured for driving a first fluid along a first flow path (85), a second fluid drive unit (20′) configured for driving a second fluid along a second flow path (86), and a fluidic switch (90) fluidically coupled to the first flow path (85) and to the second flow path (86) and configured for being switchable for transferring first fluid from the first flow path (85) into the second flow path (86) without interruption of fluid flow along at least one of the first flow path (85) and the second flow path (86).

Abstract translation: 一种用于处理流体的流体处理装置（10），其中所述流体处理装置（10）包括构造成沿着第一流动路径（85）驱动第一流体的第一流体驱动单元（20），第二流体驱动单元 被配置为沿着第二流动路径（86）驱动第二流体的流体开关（90）以及流体连接到第一流动路径（85）和第二流动路径（86）的流体开关（90），并被配置为可转换 第一流体从第一流动路径（85）进入第二流动路径（86），而不中断沿着第一流动路径（85）和第二流动路径（86）中的至少一个的流体流动。

公开(公告)号：US11999182B2

公开(公告)日：2024-06-04

申请号：US17372093

申请日：2021-07-09

Applicant: AGILENT TECHNOLOGIES, INC.

Inventor： Shaouhan Hu ,  Daniela Loraing ,  Olga Schikurski ,  Sascha Lege ,  Stephan Buckenmaier

IPC: B65D27/04 ,  B42F5/00 ,  B42F7/02 ,  B42F21/00 ,  B65D27/22 ,  B42F1/00

CPC classification number: B42F7/025 ,  B42F5/00 ,  B42F21/00 ,  B65D27/04 ,  B65D27/22 ,  B42F1/00 ,  B42P2221/06 ,  B65D2203/00

Abstract: In some examples, an organizer may include a plurality of inserts. At least one insert of the plurality of inserts may include at least a front panel and an opposite back panel that form the at least one insert, and at least one instrument component disposed hi the at least one insert. The organizer may further include a binding mechanism that attaches the plurality of inserts.

公开(公告)号：US20230112993A1

公开(公告)日：2023-04-13

申请号：US17913313

申请日：2021-03-15

Applicant: Agilent Technologies, Inc.

Inventor： Dwight Robert Stoll ,  Stephan Buckenmaier ,  Sascha Lege ,  Thomas Ortmann ,  Konstantin Shoykhet

IPC: G01N30/34 ,  B01D15/14 ,  B01D15/16 ,  G01N30/20 ,  G01N30/46

Abstract: A sample separation device for separating a fluidic sample includes a fluid drive for driving a mobile phase and the fluidic sample when injected in the mobile phase, a sample separation unit for separating the fluidic sample in the mobile phase, and a control unit configured for bracketing the fluidic sample between two mobile phase portions of the mobile phase. At least one of the mobile phase portions is arranged directly next to the fluidic sample and has a higher solvent strength compared to a solvent of the fluidic sample.

公开(公告)号：US20220308019A1

公开(公告)日：2022-09-29

申请号：US17698732

申请日：2022-03-18

Applicant: Agilent Technologies, Inc.

Inventor： Lena Höninger ,  Uwe Effelsberg ,  Gerhart Metzler ,  Sascha Lege ,  Konstantin Shoykhet ,  Stephan Buckenmaier

IPC: G01N30/36 ,  G01N30/30

Abstract: A process of controlling a sample separation apparatus for separating a fluidic sample includes determining whether the sample separation apparatus is appropriate for carrying out a predefined operation, by simulating the operation of the sample separation apparatus, and taking an action depending on a result of the determining.

公开(公告)号：US20170219540A1

公开(公告)日：2017-08-03

申请号：US15500706

申请日：2015-05-28

Applicant: Agilent Technologies, Inc.

Inventor： Herbert Anderer ,  Konstantin Shoykhet ,  Klaus Witt ,  Stephan Buckenmaier

IPC: G01N30/46

Abstract: In a method for processing successive fluidic sample portions provided by a sample source, sample reception volumes are filled successively temporarily with at least a respective one of the sample sections, and the sample sections are emptied successively out of the sample reception volumes in such a way, that, while emptying, it is avoided to bring two respective ones of the sample sections, which have not left the sample source directly adjacent to one another, in contact with one another.

公开(公告)号：US12055526B2

公开(公告)日：2024-08-06

申请号：US17045756

申请日：2019-04-05

Applicant: Agilent Technologies, Inc.

Inventor： Stephan Buckenmaier ,  Konstantin Shoykhet

IPC: G01N30/20 ,  G01N30/02 ,  G01N30/46 ,  G01N30/82 ,  G01N30/84 ,  B01D15/18

CPC classification number: G01N30/20 ,  G01N30/463 ,  G01N30/465 ,  G01N30/82 ,  B01D15/1878 ,  G01N2030/027 ,  G01N2030/202 ,  G01N2030/208 ,  G01N2030/8411

Abstract: A sampling unit for handling a sample fluid includes a sample container having a length and being configured for receiving and storing the sample fluid, and a sample segment dispatching unit configured for providing a plurality of individual sample packages of the fluidic sample, each contained in a respective volume segment along the length of the sample container, and for individually dispatching each of the plurality of individual sample packages for further processing in a fluid processing unit. The sample unit may be utilized, for example, for injecting the sample packages into a mobile phase stream for transporting to a sample separating unit such as a chromatography column.