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公开(公告)号：US20220088178A1
公开(公告)日：2022-03-24
申请号：US17489106
申请日：2021-09-29
Inventor： Tsafrir S. Leket-Mor , Bertram Jacobs , Lydia Meador , Karen Kibler
IPC: A61K39/21
Abstract: Disclosed are compositions for generating an immune response against human immunodeficiency virus (HIV) and their methods of uses.
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2.发明公开公开(公告)号：US20240226273A1
公开(公告)日：2024-07-11
申请号：US18283042
申请日：2022-03-30
Inventor： Bertram Jacobs , Karen Kibler
IPC: A61K39/215 , A61K39/00 , A61P31/14 , C12N15/86
CPC classification number: A61K39/215 , A61P31/14 , C12N15/86 , A61K2039/5256 , A61K2039/543 , C12N2710/24143 , C12N2770/20022 , C12N2770/20034 , C12N2840/105 , C12N2840/206
Abstract: Recombinant poxvirus expressing severe acute respiratory syndrome coronavirus 2 structural proteins and virus-like particles are described, along with methods of making and using the same.
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公开(公告)号：US11918642B2
公开(公告)日：2024-03-05
申请号：US17489106
申请日：2021-09-29
Inventor： Tsafrir S. Leket-Mor , Bertram Jacobs , Lydia Meador , Karen Kibler
CPC classification number: A61K39/21 , A61K2039/5258 , A61K2039/575 , C07K14/161 , C07K14/162 , C12N2740/16034 , C12N2740/16134 , C12N2740/16234
Abstract: Disclosed are compositions for generating an immune response against human immunodeficiency virus (HIV) and their methods of uses.
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Patent Agency Ranking
公开(公告)号：US20240226220A9
公开(公告)日：2024-07-11
申请号：US18277043
申请日：2022-02-11
Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY , SOUTHWEST COLLEGE OF NATUROPATHIC MEDICINE
Inventor： Jeffrey Olaf Langland , Bertram Jacobs
IPC: A61K36/539 , A61K36/287 , A61K36/537 , A61K36/78 , A61K36/82 , A61K36/888 , A61P31/14
CPC classification number: A61K36/539 , A61K36/287 , A61K36/537 , A61K36/78 , A61K36/82 , A61K36/888 , A61P31/14 , A61K2236/333
Abstract: This invention is directed to oral botanical compositions comprising plant extracts, methods of preparing the same, and methods of using the same for treating an infection.
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公开(公告)号：US20170021009A1
公开(公告)日：2017-01-26
申请号：US15125024
申请日：2015-03-10
Inventor： Bertram Jacobs , Trung Huynh , Negin Blattman , Keith Dumbell
IPC: A61K39/285 , C12N7/00
CPC classification number: A61K39/285 , A61K39/12 , A61K2039/525 , A61K2039/5252 , A61K2039/5256 , A61K2039/57 , C12N7/00 , C12N2710/24134 , C12N2710/24161
Abstract: Compositions including a heat-inactivated poxvirus, such as vaccinia virus, that induces one or more interferons in a vaccine recipient. The compositions may further include one or more live vaccine vectors and non-replicating vaccine components. Methods of vaccine preparation and administration including a heat-inactivated poxvirus, such as vaccinia virus, improve vaccine immunogenicity and safety.
Abstract translation: 包含热灭活的痘病毒（例如痘苗病毒）的组合物，其在疫苗接受者中诱导一种或多种干扰素。 组合物还可包含一种或多种活疫苗载体和非复制疫苗组分。 疫苗制备和给药方法包括热灭活的痘病毒，如痘苗病毒，提高疫苗的免疫原性和安全性。
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公开(公告)号：US20240131104A1
公开(公告)日：2024-04-25
申请号：US18277043
申请日：2022-02-11
Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY , SOUTHWEST COLLEGE OF NATUROPATHIC MEDICINE
Inventor： Jeffrey Olaf Langland , Bertram Jacobs
IPC: A61K36/539 , A61K36/287 , A61K36/537 , A61K36/78 , A61K36/82 , A61K36/888 , A61P31/14
CPC classification number: A61K36/539 , A61K36/287 , A61K36/537 , A61K36/78 , A61K36/82 , A61K36/888 , A61P31/14 , A61K2236/333
Abstract: This invention is directed to oral botanical compositions comprising plant extracts, methods of preparing the same, and methods of using the same for treating an infection.
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公开(公告)号：US20190328864A1
公开(公告)日：2019-10-31
申请号：US16396676
申请日：2019-04-27
Inventor： Tsafrir Mor , Bertram Jacobs , Lydia Meador , Karen Kibler
IPC: A61K39/21
Abstract: Disclosed are compositions for generating an immune response against human immunodeficiency virus (HIV) and their methods of uses.
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公开(公告)号：US20190183947A1
公开(公告)日：2019-06-20
申请号：US16304564
申请日：2017-05-25
Inventor： Bertram Jacobs , Heather Koehler , William Arndt , Karen Kibler , Kelly Trainor , Chandra Mitnik , Jeffrey Langland
IPC: A61K35/768 , A61P35/00 , A61K9/00
CPC classification number: A61K35/768 , A61K9/0019 , A61K45/06 , A61P35/00 , C12N7/00 , C12N2710/24121 , C12N2710/24122 , C12N2710/24132
Abstract: Methods utilizing vaccinia virus with mutations in E3L to infect and cause lysis of cancer cells with less than normal protein levels of RIP3 and/or DAI. Further, the disclosed vaccinia viruses with mutations in E3L cannot replicate well in cells with normal expression or upregulation of RIP3, DAI, and/or MLKL.
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