专利检索 ap:("Aarti Sameer Kawatkar" OR "Tara Whitney" OR "Timothy D. Neubert" OR "Nicole Hilgraf" OR "Andreas P. Termin" OR "Esther Martinborough") AND inv:"Tara Whitney" 第 1 页

1.

发明授权
Bicyclic derivatives as modulators of ion channels 有权

公开(公告)号：US08362032B2

公开(公告)日：2013-01-29

申请号：US12830743

申请日：2010-07-06

申请人： Aarti Sameer Kawatkar , Tara Whitney , Timothy D. Neubert , Nicole Hilgraf , Andreas P. Termin , Esther Martinborough

发明人： Aarti Sameer Kawatkar , Tara Whitney , Timothy D. Neubert , Nicole Hilgraf , Andreas P. Termin , Esther Martinborough

IPC分类号： C07D417/12 , A61K31/47

CPC分类号： C07D417/14 , C07D403/12 , C07D403/14 , C07D413/12 , C07D413/14 , C07D417/12

摘要： Bicyclic derivatives having formula (I) and a composition thereof are useful as ion channel antagonists:

2.

发明授权
Pyrrolidinyl phenyl sulphonamides as modulators of ion channels 有权
标题翻译：吡咯烷基苯基磺酰胺作为离子通道的调节剂

公开(公告)号：US08163720B2

公开(公告)日：2012-04-24

申请号：US12844047

申请日：2010-07-27

申请人： Esther Martinborough , Lev T. D. Fanning , Urvi Sheth , Dean Wilson , Andreas P. Termin , Timothy D. Neubert , Nicole Hilgraf , Tara Leanne Hampton , Tara Whitney , Aarti Sameer Kawatkar , Danielle Lehsten , Dean Stamos , Jinglan Zhou , Vijayalaksmi Arumugam , Corey Anderson

发明人： Esther Martinborough , Lev T. D. Fanning , Urvi Sheth , Dean Wilson , Andreas P. Termin , Timothy D. Neubert , Nicole Hilgraf , Tara Leanne Hampton , Tara Whitney , Aarti Sameer Kawatkar , Danielle Lehsten , Dean Stamos , Jinglan Zhou , Vijayalaksmi Arumugam , Corey Anderson

IPC分类号： A01N51/00 , A61N31/655

CPC分类号： C07D417/12 , C07D239/42 , C07D401/12 , C07D405/12 , C07D417/14 , C07D471/10 , C07D491/10

摘要： The present invention relates to phenyl sulfonamides useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including for example the treatment of pain.

摘要翻译： 本发明涉及可用作离子通道抑制剂的苯基磺酰胺。本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病（包括例如治疗疼痛）的方法。

3.

发明申请
PHENYL SULPHONAMIDES AS MODULATORS OF ION CHANNELS 有权
标题翻译：作为离子通道调节剂的苯乙烯磺酸盐

公开(公告)号：US20120178713A1

公开(公告)日：2012-07-12

申请号：US13419936

申请日：2012-03-14

申请人： Esther Martinborough , Lev T.D. Fanning , Urvi Sheth , Dean Wilson , Andreas P. Termin , Timothy D. Neubert , Nicole Hilgraf , Tara Leanne Hampton , Tara Whitney , Aarti Sameer Kawatkar , Danielle Lehsten , Dean Stamos , Jinglan Zhou , Vijayalaksmi Arumugam , Corey Anderson

发明人： Esther Martinborough , Lev T.D. Fanning , Urvi Sheth , Dean Wilson , Andreas P. Termin , Timothy D. Neubert , Nicole Hilgraf , Tara Leanne Hampton , Tara Whitney , Aarti Sameer Kawatkar , Danielle Lehsten , Dean Stamos , Jinglan Zhou , Vijayalaksmi Arumugam , Corey Anderson

IPC分类号： A61K31/496 , C07D403/12 , A61K31/506 , C07D417/14 , A61K31/501 , A61K31/454 , C07D471/04 , A61K31/437 , A61K31/427 , C07F7/02 , A61K31/695 , C07D413/14 , A61K31/5377 , A61P35/00 , A61P19/02 , A61P25/06 , A61P25/08 , A61P25/28 , A61P25/22 , A61P25/24 , A61P1/00 , A61P13/02 , C07D417/12

CPC分类号： C07D417/12 , C07D239/42 , C07D401/12 , C07D405/12 , C07D417/14 , C07D471/10 , C07D491/10

摘要： The present invention relates to phenyl sulfonamides useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including for example the treatment of pain.

摘要翻译： 本发明涉及可用作离子通道抑制剂的苯基磺酰胺。本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病（包括例如治疗疼痛）的方法。

4.

发明申请
PHENYL SULFONAMIDES AS MODULATORS OF ION CHANNELS 有权
标题翻译：苯基磺酰胺作为离子通道的调节剂

公开(公告)号：US20110082117A1

公开(公告)日：2011-04-07

申请号：US12844047

申请日：2010-07-27

申请人： Esther Martinborough , Lev T.D. Fanning , Urvi Sheth , Dean Wilson , Andreas P. Termin , Timothy D. Neubert , Nicole Hilgraf , Tara Leanne Hampton , Tara Whitney , Aarti Sameer Kawatkar , Danielle Lehsten , Dean Stamos , Jinglan Zhou , Vijayalaksmi Arumugam , Corey Anderson

发明人： Esther Martinborough , Lev T.D. Fanning , Urvi Sheth , Dean Wilson , Andreas P. Termin , Timothy D. Neubert , Nicole Hilgraf , Tara Leanne Hampton , Tara Whitney , Aarti Sameer Kawatkar , Danielle Lehsten , Dean Stamos , Jinglan Zhou , Vijayalaksmi Arumugam , Corey Anderson

IPC分类号： A61K31/635 , A61K31/454 , A61K31/4178 , A61P29/00 , A61P25/00 , A61P13/00 , A61P17/00

CPC分类号： C07D417/12 , C07D239/42 , C07D401/12 , C07D405/12 , C07D417/14 , C07D471/10 , C07D491/10

摘要： The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

摘要翻译： 本发明涉及可用作离子通道抑制剂的杂环衍生物。本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病的方法。

5.

发明申请
BICYCLIC DERIVATIVES AS MODULATORS OF ION CHANNELS 有权
标题翻译：双离子衍生物作为离子通道的调节剂

公开(公告)号：US20110059965A1

公开(公告)日：2011-03-10

申请号：US12830743

申请日：2010-07-06

申请人： Aarti Sameer Kawatkar , Tara Whitney , Timothy D. Neubert , Nicole Hilgraf , Andreas P. Termin , Esther Martinborough

发明人： Aarti Sameer Kawatkar , Tara Whitney , Timothy D. Neubert , Nicole Hilgraf , Andreas P. Termin , Esther Martinborough

IPC分类号： A61K31/5377 , A61K31/427 , A61K31/433 , A61K31/4725 , A61K31/4709 , A61K31/4439 , A61K31/506 , A61K31/501 , A61K31/454 , A61P29/00 , A61P19/02 , A61P25/06 , A61P3/10 , A61P35/00

CPC分类号： C07D417/14 , C07D403/12 , C07D403/14 , C07D413/12 , C07D413/14 , C07D417/12

摘要： Bicyclic derivatives having formula (I) and a composition thereof are useful as ion channel antagonists:

摘要翻译： 具有式（I）的双环衍生物及其组合物可用作离子通道拮抗剂：

6.

发明申请
Piperidine and Piperazine Phenyl Sulfonamides as Modulators of Ion Channels 有权
标题翻译：哌啶和哌嗪苯磺酰胺作为离子通道的调节剂

公开(公告)号：US20130035310A1

公开(公告)日：2013-02-07

申请号：US13633478

申请日：2012-10-02

申请人： Esther Ann Martinborough , Lev Tyler Dewey Fanning , Urvi Jagdishbhai Sheth , Dean Mitchell Wilson , Andreas P. Termin , Timothy Donald Neubert , Nicole Hilgraf , Tara Leanne Hampton , Tara Whitney , Aarti Sameer Kawatkar , Danielle Lehsten , Dean Stamos , Jinglan Zhou , Vijayalaksmi Arumugam , Corey Anderson

发明人： Esther Ann Martinborough , Lev Tyler Dewey Fanning , Urvi Jagdishbhai Sheth , Dean Mitchell Wilson , Andreas P. Termin , Timothy Donald Neubert , Nicole Hilgraf , Tara Leanne Hampton , Tara Whitney , Aarti Sameer Kawatkar , Danielle Lehsten , Dean Stamos , Jinglan Zhou , Vijayalaksmi Arumugam , Corey Anderson

IPC分类号： A61K31/635 , A61K31/454 , A61K31/4545 , A61K31/496 , A61K31/427 , A61K31/695 , A61P29/00 , A61P25/06 , A61P25/00 , A61P25/22 , A61P25/24 , A61P25/08 , A61P9/06 , A61P25/28 , A61P19/02 , A61P9/12 , A61P1/00 , A61K31/506

CPC分类号： C07D417/12 , C07D239/42 , C07D401/12 , C07D405/12 , C07D417/14 , C07D471/10 , C07D491/10

摘要： The present invention relates to piperidine and piperazine phenyl sulfonamides useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including for example the treatment of pain.

摘要翻译： 本发明涉及可用作离子通道抑制剂的哌啶和哌嗪苯基磺酰胺。本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病（包括例如治疗疼痛）的方法。

7.

发明授权
Piperidine and piperazine phenyl sulphonamides as modulators of ion channels 有权
标题翻译：哌啶和哌嗪苯磺酰胺作为离子通道的调节剂

公开(公告)号：US08309587B2

公开(公告)日：2012-11-13

申请号：US13419936

申请日：2012-03-14

申请人： Esther Ann Martinborough , Lev Tyler Dewey Fanning , Urvi Jagdishbhai Sheth , Dean Mitchell Wilson , Andreas P. Termin , Timothy Donald Neubert , Nicole Hilgraf , Tara Leanne Hampton , Tara Whitney , Aarti Sameer Kawatkar , Danielle Lehsten , Dean Stamos , Jinglan Zhou , Vijayalaksmi Arumugam , Corey Anderson

发明人： Esther Ann Martinborough , Lev Tyler Dewey Fanning , Urvi Jagdishbhai Sheth , Dean Mitchell Wilson , Andreas P. Termin , Timothy Donald Neubert , Nicole Hilgraf , Tara Leanne Hampton , Tara Whitney , Aarti Sameer Kawatkar , Danielle Lehsten , Dean Stamos , Jinglan Zhou , Vijayalaksmi Arumugam , Corey Anderson

IPC分类号： A01N43/78 , A61K31/425

CPC分类号： C07D417/12 , C07D239/42 , C07D401/12 , C07D405/12 , C07D417/14 , C07D471/10 , C07D491/10

摘要： The present invention relates to piperidine and piperazine phenyl sulfonamides useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including for example the treatment of pain.

摘要翻译： 本发明涉及可用作离子通道抑制剂的哌啶和哌嗪苯基磺酰胺。本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病（包括例如治疗疼痛）的方法。

8.

发明授权
Pyrrolidinone benzenesulfonamide derivatives as modulators of ion channels for the treatment of pain 有权
标题翻译：吡咯烷酮苯磺酰胺衍生物作为离子通道的调节剂治疗疼痛

公开(公告)号：US07994166B2

公开(公告)日：2011-08-09

申请号：US12269108

申请日：2008-11-12

申请人： Dean Stamos , Esther Martinborough , Nicole Zimmermann , Timothy Neubert , Mehdi Michel Djamel Numa , Tara Whitney , Aarti Sameer Kawatkar

发明人： Dean Stamos , Esther Martinborough , Nicole Zimmermann , Timothy Neubert , Mehdi Michel Djamel Numa , Tara Whitney , Aarti Sameer Kawatkar

IPC分类号： A61K31/5355 , C07D417/14

CPC分类号： C07D417/14

摘要： The present invention relates to pyrrolidinone benzenesulfonamide derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of pain.

摘要翻译： 本发明涉及可用作离子通道抑制剂的吡咯烷酮苯磺酰胺衍生物。本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗疼痛的方法。

9.

发明申请
PYRROLIDINONE BENZENESULFONAMIDE DERIVATIVES AS MODULATORS OF ION CHANNELS FOR THE TREATMENT OF PAIN 审中-公开
标题翻译：作为治疗疼痛的离子通道的调节剂，吡咯烷酮苯并呋喃衍生物

公开(公告)号：US20120010416A1

公开(公告)日：2012-01-12

申请号：US13178877

申请日：2011-07-08

申请人： Dean Stamos , Esther Martinborough , Nicole Zimmermann , Timothy Neubert , Mehdi Michel Djamel Numa , Tara Whitney , Aarti Sameer Kawatkar

发明人： Dean Stamos , Esther Martinborough , Nicole Zimmermann , Timothy Neubert , Mehdi Michel Djamel Numa , Tara Whitney , Aarti Sameer Kawatkar

IPC分类号： C07D417/14

CPC分类号： C07D417/14

摘要： The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

摘要翻译： 本发明涉及可用作离子通道抑制剂的杂环衍生物。本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病的方法。

10.

发明申请
HETEROCYCLIC DERIVATIVES AS MODULATORS OF ION CHANNELS 有权

公开(公告)号：US20090131440A1

公开(公告)日：2009-05-21

申请号：US12269108

申请日：2008-11-12

申请人： Dean Stamos , Esther Martinborough , Nicole Zimmermann , Timothy Neubert , Mehdi Michel Djamel Numa , Tara Whitney , Aarti Sameer Kawatkar

发明人： Dean Stamos , Esther Martinborough , Nicole Zimmermann , Timothy Neubert , Mehdi Michel Djamel Numa , Tara Whitney , Aarti Sameer Kawatkar

IPC分类号： A61K31/5377 , C07D417/14 , A61K31/454 , A61P25/00

CPC分类号： C07D417/14

摘要： The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

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