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公开(公告)号:US11116430B2
公开(公告)日:2021-09-14
申请号:US17145655
申请日:2021-01-11
发明人: Jeffery V. Funderburk , Duane O. Yamasaki , Brian VanHiel , Stephen J. Flynn , Bradley D. Keleman
IPC分类号: A61B5/145 , A61B5/00 , G16H10/40 , G16H50/30 , G16H50/00 , A61B5/1473 , A61B17/34 , A61N1/05 , G16H10/60
摘要: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion.
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公开(公告)号:US20200345282A1
公开(公告)日:2020-11-05
申请号:US16928700
申请日:2020-07-14
发明人: Jeffery V. Funderburk , Duane O. Yamasaki , Brian VanHiel , Stephen J. Flynn , Bradley D. Kelemen
IPC分类号: A61B5/145 , A61B5/00 , A61B5/1473 , A61B17/34
摘要: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion.
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公开(公告)号:US09891185B2
公开(公告)日:2018-02-13
申请号:US15155681
申请日:2016-05-16
发明人: Benjamin J. Feldman , Adam Heller , Ephraim Heller , Fei Mao , Joseph A. Vivolo , Jeffery V. Funderburk , Fredric C. Colman , Rajesh Krishnan
IPC分类号: G01N27/327 , C12Q1/00 , C12Q1/32
CPC分类号: G01N27/3272 , C12Q1/001 , C12Q1/006 , C12Q1/32 , G01N27/3271 , G01N27/3274 , Y10T29/49002 , Y10T29/49004 , Y10T29/49007 , Y10T29/49126 , Y10T29/49128 , Y10T29/4913 , Y10T29/49147 , Y10T29/49155 , Y10T29/49204 , Y10T29/49208 , Y10T29/4921 , Y10T29/49794 , Y10T156/1052
摘要: A sensor utilizing a non-leachable or diffusible redox mediator is described. The sensor includes a sample chamber to hold a sample in electrolytic contact with a working electrode, and in at least some instances, the sensor also contains a non-leachable or a diffusible second electron transfer agent. The sensor and/or the methods used produce a sensor signal in response to the analyte that can be distinguished from a background signal caused by the mediator. The invention can be used to determine the concentration of a biomolecule, such as glucose or lactate, in a biological fluid, such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. An enzyme capable of catalyzing the electrooxidation or electroreduction of the biomolecule is typically provided as a second electron transfer agent.
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公开(公告)号:US20170202491A1
公开(公告)日:2017-07-20
申请号:US15478134
申请日:2017-04-03
IPC分类号: A61B5/1495 , A61B5/1486 , A61B5/00 , A61B5/145
CPC分类号: A61B5/1495 , A61B5/0002 , A61B5/0022 , A61B5/0031 , A61B5/076 , A61B5/14503 , A61B5/14532 , A61B5/14546 , A61B5/1473 , A61B5/1486 , A61B5/14865 , A61B5/4839 , A61B5/6832 , A61B5/6833 , A61B5/6849 , A61B5/7405 , A61B5/742 , A61B5/743 , A61B5/7445 , A61B2560/0252 , A61B2560/0412 , A61B2560/063 , A61N1/08 , H04B1/707 , H04L1/0071
摘要: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor.
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公开(公告)号:US20150025345A1
公开(公告)日:2015-01-22
申请号:US14509993
申请日:2014-10-08
发明人: Jeffery V. Funderburk , Duane O. Yamasaki , Brian VanHiel , Stephen J. Flynn , Bradley D. Kelemen
IPC分类号: A61B5/1473 , A61B5/00 , A61B17/34 , A61B5/145
CPC分类号: A61B5/1473 , A61B5/1451 , A61B5/14532 , A61B5/14542 , A61B5/14546 , A61B5/6833 , A61B5/6849 , A61B17/3468 , A61M2205/3507 , A61M2230/201 , A61N1/05 , A61N1/08
摘要: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion.
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公开(公告)号:US20220022785A1
公开(公告)日:2022-01-27
申请号:US17493408
申请日:2021-10-04
发明人: Jeffery V. Funderburk , Duane O. Yamasaki , Brian VanHiel , Stephen J. Flynn , Bradley D. Kelemen
摘要: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion.
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公开(公告)号:US11141084B2
公开(公告)日:2021-10-12
申请号:US16928700
申请日:2020-07-14
发明人: Jeffery V. Funderburk , Duane O. Yamasaki , Brian VanHiel , Stephen J. Flynn , Bradley D. Kelemen
IPC分类号: A61B5/145 , A61B5/00 , G16H10/40 , G16H50/30 , G16H50/00 , A61B5/1473 , A61B17/34 , A61N1/05 , G16H10/60
摘要: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion.
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公开(公告)号:US20190000356A1
公开(公告)日:2019-01-03
申请号:US15963828
申请日:2018-04-26
发明人: Jeffery V. Funderburk , Duane O. Yamaski , Brian VanHiel , Stephen J. Flynn , Bradley D. Kelemen
IPC分类号: A61B5/1473 , A61B17/34 , A61B5/00 , A61B5/145
摘要: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion.
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公开(公告)号:US09980670B2
公开(公告)日:2018-05-29
申请号:US14244831
申请日:2014-04-03
发明人: Jeffery V. Funderburk , Duane O. Yamasaki , Brian VanHiel , Stephen J. Flynn , Bradley D. Kelemen
CPC分类号: A61B5/1473 , A61B5/1451 , A61B5/14532 , A61B5/14542 , A61B5/14546 , A61B5/6833 , A61B5/6849 , A61B17/3468 , A61M2205/3507 , A61M2230/201 , A61N1/05 , A61N1/08
摘要: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion.
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公开(公告)号:US20180128767A1
公开(公告)日:2018-05-10
申请号:US15861048
申请日:2018-01-03
发明人: Benajmin J. Feldman , Adam Heller , Ephraim Heller , Fei Mao , Joseph A. Vivolo , Jeffery V. Funderburk , Fredric C. Colman , Rajesh Krishnan
IPC分类号: G01N27/327 , C12Q1/00 , C12Q1/32
CPC分类号: G01N27/3272 , C12Q1/001 , C12Q1/006 , C12Q1/32 , G01N27/3271 , G01N27/3274 , Y10T29/49002 , Y10T29/49004 , Y10T29/49007 , Y10T29/49126 , Y10T29/49128 , Y10T29/4913 , Y10T29/49147 , Y10T29/49155 , Y10T29/49204 , Y10T29/49208 , Y10T29/4921 , Y10T29/49794 , Y10T156/1052
摘要: A sensor utilizing a non-leachable or diffusible redox mediator is described. The sensor includes a sample chamber to hold a sample in electrolytic contact with a working electrode, and in at least some instances, the sensor also contains a non-leachable or a diffusible second electron transfer agent. The sensor and/or the methods used produce a sensor signal in response to the analyte that can be distinguished from a background signal caused by the mediator. The invention can be used to determine the concentration of a biomolecule, such as glucose or lactate, in a biological fluid, such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. An enzyme capable of catalyzing the electrooxidation or electroreduction of the biomolecule is typically provided as a second electron transfer agent.
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