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公开(公告)号：US20060155179A1
公开(公告)日：2006-07-13
申请号：US10545220
申请日：2004-02-13
申请人： Achim Muller , Roland Schmieder , Klaus Haberstroh
发明人： Achim Muller , Roland Schmieder , Klaus Haberstroh
IPC分类号： A61B5/00
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/6821
摘要： The present invention relates to a hand-held fluorescence photometer and method for measuring an analyte level, preferably a blood glucose level, from an ocular fluid. The photometer is based on a dual beams measuring system and it is capable of defining the correct positioning for the measurement. Only when the apparatus is correctly positioned the actual analyte measurement automatically takes place.
摘要翻译： 本发明涉及用于从眼液测量分析物水平，优选血糖水平的手持荧光光度计和方法。 光度计基于双光束测量系统，它能够定义测量的正确定位。 只有当设备正确定位时，才会自动进行实际的分析物测量。
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公开(公告)号：US07406345B2
公开(公告)日：2008-07-29
申请号：US10545220
申请日：2004-02-13
申请人： Achim Müller , Roland Schmieder , Klaus Haberstroh
发明人： Achim Müller , Roland Schmieder , Klaus Haberstroh
IPC分类号： A61B5/1455
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/6821
摘要： The present invention relates to a hand-held fluorescence photometer and method for measuring an analyte level, preferably a blood glucose level, from an ocular fluid. The photometer is based on a dual beams measuring system and it is capable of defining the correct positioning for the measurement. Only when the apparatus is correctly positioned the actual analyte measurement automatically takes place.
摘要翻译： 本发明涉及用于从眼液测量分析物水平，优选血糖水平的手持荧光光度计和方法。 光度计基于双光束测量系统，它能够定义测量的正确定位。 只有当设备正确定位时，才会自动进行实际的分析物测量。
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公开(公告)号：US20050176158A1
公开(公告)日：2005-08-11
申请号：US10653866
申请日：2003-09-03
申请人： Achim Muller , Roland Schmieder , Katharina Schmid
发明人： Achim Muller , Roland Schmieder , Katharina Schmid
IPC分类号： G02C7/04 , A61B3/10 , A61B10/00 , G01N33/487 , G01N33/543
CPC分类号： G01N33/487 , A61B2010/0067
摘要： The present invention concerns a process for analyzing an analyte in a hydrogel contact lens following its wear on the eye, comprising the steps of (a) physically or chemically inducing a volume reduction of the hydrogel contact lens and thereby squeezing the analyte out of the polymer material making up the contact lens and (b) feeding the analyte obtained according to step (a) into an analyzer. The process of the invention provides a new concept for noninvasively measuring various analytes occurring in the tear fluid that is comfortable to the user.
摘要翻译： 本发明涉及一种用于分析水凝胶隐形眼镜在眼睛上的磨损后的分析物的方法，包括以下步骤：（a）物理或化学诱导水凝胶隐形眼镜的体积减少，从而将分析物挤出聚合物 构成隐形眼镜的材料和（b）将根据步骤（a）获得的分析物进料到分析器中。 本发明的方法提供了用于非侵入性地测量在用户舒适的泪液中出现的各种分析物的新概念。
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公开(公告)号：US20060148983A1
公开(公告)日：2006-07-06
申请号：US10544725
申请日：2004-02-27
申请人： Achim Muller , Roland Schmieder , Katharina Schmid
发明人： Achim Muller , Roland Schmieder , Katharina Schmid
IPC分类号： C08F116/06
摘要： The present invention relates to a copolymer, which is the reaction product of (a) a first prepolymer, comprising a bioactive moiety and at least one radically polymerizable group, and (b) a second prepolymer which is a polyvinyl alcohol having a weight average molecular weight of at least about 2000 that, based on the number of hydroxy groups of the polyvinyl alcohol, comprises from 0.5 to 80% structural units of formula (I) wherein: R is alkylene having up to 8 carbon atoms, R1 is hydrogen or alkyl having up to seven carbon atoms, and R2 is an olefinically unsaturated, electron-attracting copolymerizable radical.
摘要翻译： 本发明涉及一种共聚物，它是（a）包含生物活性部分和至少一个可自由基聚合基团的第一预聚物的反应产物，和（b）第二预聚物，其是具有重均分子量 至少约2000重量，基于聚乙烯醇的羟基数，包含0.5至80％的式（I）结构单元，其中：R是具有至多8个碳原子的亚烷基，R 1 H 2是具有至多7个碳原子的氢或烷基，R 2是烯属不饱和的吸电子共聚基团。
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公开(公告)号：US20060077341A1
公开(公告)日：2006-04-13
申请号：US11226604
申请日：2005-09-14
申请人： Barry Atkins , Norbert Doerr , Alfred Fischer , Michael Quinn , Roland Schmieder , Robert Tucker
发明人： Barry Atkins , Norbert Doerr , Alfred Fischer , Michael Quinn , Roland Schmieder , Robert Tucker
IPC分类号： G02C7/04
CPC分类号： B29D11/00865 , B29D11/00903 , D06P5/003 , D06P5/007 , D06P5/2005 , G02B1/043
摘要： The invention provides a method for producing colored contact lenses with high quality color images. The method of the invention comprises the steps of (a) providing a water based ink in at least one cliche wherein a pattern to be printed on the contact lens has been created; (b) transferring the water based ink from the cliché to at least a surface of at least a contact lens forming mold by means of at least a transfer pad; (c) at least partially curing the ink transferred on the mold to form a colored film; (d) dispensing a hydrogel lens-forming material into a lens-forming cavity of the mold; and (e) curing the lens-forming material within the lens-forming cavity to form the contact lens, whereby the colored film detaches from the molding surface and becomes integral with the body of the contact lens; characterized in that the relative air humidity in the immediate vicinities of the transfer pad/s is kept higher than 50% at standard temperature and pressure conditions during ink transfer.
摘要翻译： 本发明提供一种生产具有高质量彩色图像的彩色隐形眼镜的方法。 本发明的方法包括以下步骤：（a）在至少一个刻薄中提供水性油墨，其中已经形成要被印刷在隐形眼镜上的图案; （b）借助于至少一个转印垫将水基油墨从陈年代转移到至少一个隐形眼镜成型模的表面; （c）至少部分地固化在模具上转印的油墨以形成着色膜; （d）将水凝胶透镜形成材料分配到模具的透镜形成腔中; 和（e）固化透镜形成腔内的透镜形成材料以形成隐形眼镜，由此着色膜从模制表面脱离并与隐形眼镜的主体成一体; 其特征在于，在墨水转印期间，在标准温度和压力条件下，传送垫的紧邻附近的相对空气湿度保持高于50％。
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公开(公告)号：US20090113851A1
公开(公告)日：2009-05-07
申请号：US12290329
申请日：2008-10-29
申请人： Stephen N. Carr , James Shay Foley , Kent M. Grothe , Roland Schmieder , Charles Henry Walton, IV
发明人： Stephen N. Carr , James Shay Foley , Kent M. Grothe , Roland Schmieder , Charles Henry Walton, IV
IPC分类号： B65B51/10
CPC分类号： B65B7/2878 , B29C65/18 , B29C65/76 , B29C66/112 , B29C66/131 , B29C66/232 , B29C66/242 , B29C66/244 , B29C66/53461 , B29C66/72343 , B29C66/7373 , B29C66/8122 , B29C66/81415 , B29C66/81422 , B29C66/81427 , B29C66/81433 , B29C66/81435 , B29C66/8167 , B29C66/849 , B29K2705/00 , B29K2905/02 , B29K2905/06 , B29K2905/10 , B29K2905/12 , B29K2995/0069 , B29L2011/0041 , B29L2031/7164 , B65B7/164 , B65B25/008 , B65B51/14
摘要： A seal plate for use in sealing ophthalmic lens blister packages having a laminate foil cover and plastic shell for containing an ophthalmic lens and lens solution therein, the seal plate including a heated plate body and sealing face. The sealing face protrudes from the plate body and has an irregular shape. The sealing face further engages the laminate foil cover and displaces moisture present between the foil cover and plastic bowl body to induce a heat seal therebetween.
摘要翻译： 一种用于密封眼镜镜片泡罩包装的密封板，其具有层压箔盖和用于在其中容纳眼镜片和透镜溶液的塑料外壳，所述密封板包括加热的板体和密封面。 密封面从板体突出并且具有不规则形状。 密封面还与层压箔片盖接合，并且移动存在于箔盖和塑料碗体之间的水分以在其间引起热封。
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公开(公告)号：US07429465B2
公开(公告)日：2008-09-30
申请号：US10653866
申请日：2003-09-03
申请人： Achim Müller , Roland Schmieder , Katharina Schmid
发明人： Achim Müller , Roland Schmieder , Katharina Schmid
CPC分类号： G01N33/487 , A61B2010/0067
摘要： The present invention concerns a process for analyzing an analyte in a hydrogel contact lens following its wear on the eye, comprising the steps of (a) physically or chemically inducing a volume reduction of the hydrogel contact lens and thereby squeezing the analyte out of the polymer material making up the contact lens and (b) feeding the analyte obtained according to step (a) into an analyzer. The process of the invention provides a new concept for noninvasively measuring various analytes occurring in the tear fluid that is comfortable to the user.
摘要翻译： 本发明涉及一种用于分析水凝胶隐形眼镜在眼睛上的磨损后的分析物的方法，包括以下步骤：（a）物理或化学诱导水凝胶隐形眼镜的体积减少，从而将分析物挤出聚合物 构成隐形眼镜的材料和（b）将根据步骤（a）获得的分析物进料到分析器中。 本发明的方法提供了用于非侵入性地测量在用户舒适的泪液中出现的各种分析物的新概念。
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公开(公告)号：US09039173B2
公开(公告)日：2015-05-26
申请号：US13186737
申请日：2011-07-20
CPC分类号： G02C7/046 , B29D11/00903 , G02C2202/16
摘要： The invention is directed to a colored contact lens designed for making a wearer's eyes to appear larger, bolder, and enhanced color while giving the wearer's eyes a very natural appearance. A colored contact lens of the invention comprising a first print of a first color and a second print of a second color, wherein the first print consisting of an annular ring of gradient dot matrix, wherein the second print comprises a limbal ring and an outer starburst pattern, wherein the limbal ring surrounds the outer starburst pattern, wherein the annular ring and the limbal ring have a substantially identical outer diameter and the annular ring has a larger inside diameter than the limbal ring, the first color and the second color are different or the same, wherein the first print and the second print are concentric with the center of contact lens.
摘要翻译： 本发明涉及一种彩色隐形眼镜，其设计用于使佩戴者的眼睛看起来更大，更大胆和增强的颜色，同时给予佩戴者的眼睛非常自然的外观。 本发明的彩色隐形眼镜包括第一颜色和第二颜色的第二印刷品的第一印刷品，其中所述第一印刷品由渐变点阵的环形环组成，其中所述第二印刷品包括边缘环和外星爆 其中所述边缘环围绕所述外星爆图案，其中所述环形圈和所述边缘环具有基本上相同的外径，并且所述环形圈具有比所述边缘环更大的内径，所述第一颜色和所述第二颜色不同或 相同，其中第一印刷品和第二印刷品与隐形眼镜的中心同心。
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公开(公告)号：US20120026459A1
公开(公告)日：2012-02-02
申请号：US13186737
申请日：2011-07-20
CPC分类号： G02C7/046 , B29D11/00903 , G02C2202/16
摘要： The invention is directed to a colored contact lens designed for making a wearer's eyes to appear larger, bolder, and enhanced color while giving the wearer's eyes a very natural appearance. A colored contact lens of the invention comprising a first print of a first color and a second print of a second color, wherein the first print consisting of an annular ring of gradient dot matrix, wherein the second print comprises a limbal ring and an outer starburst pattern, wherein the limbal ring surrounds the outer starburst pattern, wherein the annular ring and the limbal ring have a substantially identical outer diameter and the annular ring has a larger inside diameter than the limbal ring, the first color and the second color are different or the same, wherein the first print and the second print are concentric with the center of contact lens.
摘要翻译： 本发明涉及一种彩色隐形眼镜，其设计用于使佩戴者的眼睛看起来更大，更大胆和增强的颜色，同时给予佩戴者的眼睛非常自然的外观。 本发明的彩色隐形眼镜包括第一颜色和第二颜色的第二印刷品的第一印刷品，其中所述第一印刷品由渐变点阵的环形环组成，其中所述第二印刷品包括边缘环和外星爆 其中所述边缘环围绕所述外星爆图案，其中所述环形圈和所述边缘环具有基本上相同的外径，并且所述环形圈具有比所述边缘环更大的内径，所述第一颜色和所述第二颜色不同或 相同，其中第一印刷品和第二印刷品与隐形眼镜的中心同心。
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公开(公告)号：US07772286B2
公开(公告)日：2010-08-10
申请号：US10544725
申请日：2004-02-27
申请人： Achim Müller , Roland Schmieder , Katharina Schmid
发明人： Achim Müller , Roland Schmieder , Katharina Schmid
IPC分类号： C08F8/00 , C08F116/06 , C08F299/00
摘要： The present invention relates to a copolymer, which is the reaction product of (a) a first prepolymer, comprising a bioactive moiety and at least one radically polymerizable group, and (b) a second prepolymer which is a polyvinyl alcohol having a weight average molecular weight of at least about 2000 that, based on the number of hydroxy groups of the polyvinyl alcohol, comprises from 0.5 to 80% structural units of formula (I) wherein: R is alkylene having up to 8 carbon atoms, R1 is hydrogen or alkyl having up to seven carbon atoms, and R2 is an olefinically unsaturated, electron-attracting copolymerizable radical.
摘要翻译： 本发明涉及一种共聚物，它是（a）包含生物活性部分和至少一个可自由基聚合基团的第一预聚物的反应产物，和（b）第二预聚物，其是具有重均分子量 至少约2000重量，基于聚乙烯醇的羟基数，包含0.5至80％的式（I）结构单元，其中：R是具有至多8个碳原子的亚烷基，R 1是氢或烷基 具有至多7个碳原子，并且R 2是烯属不饱和的吸电子共聚基团。
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