Crosslinked tinted polymers
    1.
    发明授权
    Crosslinked tinted polymers 失效
    交联着色聚合物

    公开(公告)号:US5871675A

    公开(公告)日:1999-02-16

    申请号:US875532

    申请日:1997-09-18

    摘要: The invention relates to a novel process for the production of tinted mouldings, in particular tinted contact lenses, in which a crosslinkable tinted polymer comprising units containing a crosslinkable group and units containing a reactive dye radical is crosslinked in solution, and to tinted mouldings, in particular tinted contact lenses, obtainable by this process. The present invention likewise relates to novel crosslinkable tinted polymers comprising units containing a crosslinkable group and units containing a reactive dye radical which can be employed in the novel process, in particular derivatives of a polyvinyl alcohol having a molecular weight of at least about 2000, to crosslinked tinted polymers, either homopolymers or copolymers, made from these novel crosslinkable tinted polymers containing a reactive dye radical, a process for the preparation of the novel crosslinkable tinted polymers comprising units containing a crosslinkable group and units containing a reactive dye radical and the homopolymers and copolymers obtainable therefrom, to tinted mouldings made from said homopolymers or copolymers, in particular tinted contact lenses made from these homopolymers or copolymers, and to a process for the production of tinted contact lenses using said homopolymers or copolymers.

    摘要翻译: PCT No.PCT / EP96 / 00252 Sec。 371日期:1997年9月18日 102(e)1997年9月18日PCT PCT 1996年1月23日PCT公布。 公开号WO96 / 24076 日期1996年8月8日本发明涉及一种生产有色成型品,特别是着色隐形眼镜的新方法,其中包含含有可交联基团的单元的交联着色聚合物和含有活性染料基团的单元在溶液中交联, 用于通过该方法获得的有色成型品,特别是有色隐形眼镜。 本发明同样涉及包含可交联基团的单元的新型交联着色聚合物和可用于新方法的反应性染料基团的单元,特别是分子量至少为约2000的聚乙烯醇的衍生物,至 交联着色聚合物,均聚物或共聚物,由含有活性染料基团的这些新型可交联着色聚合物制成,制备包含可交联基团的单元的新交联着色聚合物的方法和含有活性染料基团的单元和均聚物和 可从其获得的共聚物到由所述均聚物或共聚物制成的着色模制品,特别是由这些均聚物或共聚物制成的着色隐形眼镜,以及使用所述均聚物或共聚物生产着色隐形眼镜的方法。

    Polymeric networks from water-soluble prepolymers
    2.
    发明授权
    Polymeric networks from water-soluble prepolymers 失效
    来自水溶性预聚物的聚合物网络

    公开(公告)号:US5665840A

    公开(公告)日:1997-09-09

    申请号:US552649

    申请日:1995-11-03

    摘要: The present invention describes a water-soluble crosslinkable prepolymer that comprises, in the copolymer chain, units derived from the following monomeric structural units: a vinyl lactam (a), vinyl alcohol (b), optionally a lower alkanecarboxylic acid vinyl ester (c), a vinylic crosslinking agent (d) and optionally a vinylic photoinitiator (e); a process for the preparation of the novel prepolymers; crosslinked water-insoluble polymeric networks therefrom; hydrogels and moulded articles made from the crosslinked water-insoluble polymeric networks, especially contact lenses; and a process for the manufacture of hydrogels and finished contact lenses using the mentioned crosslinkable water-soluble prepolymers.

    摘要翻译: 本发明描述了一种水溶性可交联预聚物,其在共聚物链中包含衍生自以下单体结构单元的单元:乙烯基内酰胺(a),乙烯醇(b),任选的低级链烷羧酸乙烯基酯(c) 乙烯基交联剂(d)和任选的乙烯基光引发剂(e); 一种制备新型预聚物的方法; 交联的水不溶性聚合物网络; 由交联的水不溶性聚合物网络制成的水凝胶和模塑制品,特别是隐形眼镜; 以及使用所述可交联水溶性预聚物制造水凝胶和成品隐形眼镜的方法。

    Combined Apparatus For Measuring the Blood Glucose Level From an Ocular Fluid
    3.
    发明申请
    Combined Apparatus For Measuring the Blood Glucose Level From an Ocular Fluid 审中-公开
    用于从眼液测量血糖水平的组合仪器

    公开(公告)号:US20080249381A1

    公开(公告)日:2008-10-09

    申请号:US11570628

    申请日:2005-06-13

    IPC分类号: A61B5/00

    摘要: A combined apparatus for measuring the blood glucose level from an ocular fluid comprises a hand-held fluorescence photometer (D1) for determining the glucose level of the ocular fluid and a device (D2) for the amperometric or photometric determination of the blood glucose level. The fluorescence photometer (D1) comprises: first irradiating means (7,8,10) for providing a pilot beam (1) for irradiation of the eye (3) in order to excite a first fluorescence comprising a first wavelength band; first detecting means (8,9,12,13) for measuring the intensity of the of the pupil fluorescence within the first wavelength band; second irradiating means (17,18,21) for providing a measurement beam (5) for irradiation of the eye in order to excite an ocular sensor (4) to emit a second fluorescence comprising a second wavelength band; second detecting means (18,19,20,22,23,24,25) for measuring the intensity of the second fluorescence within the second wavelength band. The first and second irradiating means are arranged such that the measurement beam irradiates the eye under a predetermined angle (a) between 0° and 90° and at a predetermined distance from the pilot beam.

    摘要翻译: 用于测量来自眼液的血糖水平的组合装置包括用于确定眼液的葡萄糖水平的手持荧光光度计(D 1)和用于血糖的电流或光度测定的装置(D 2) 水平。 荧光光度计(D 1)包括:第一照射装置(7,8,10),用于提供用于照射眼睛(3)的引导光束(1),以便激发包括第一波长带的第一荧光; 第一检测装置(8,9,12,13),用于测量第一波长带内的瞳孔荧光的强度; 第二照射装置(17,18,21),用于提供用于照射眼睛的测量光束(5),以激发眼睛传感器(4)以发射包括第二波长带的第二荧光; 用于测量第二波长带内的第二荧光的强度的第二检测装置(18,19,20,22,23,24,25)。 第一和第二照射装置被布置成使得测量光束以0°至90°之间的预定角度(a)照射眼睛并且距离导向光束预定距离。

    Methods and compositions for manufacturing tinted ophthalmic lenses
    4.
    发明授权
    Methods and compositions for manufacturing tinted ophthalmic lenses 有权
    用于制造有色眼镜的方法和组合物

    公开(公告)号:US6149842A

    公开(公告)日:2000-11-21

    申请号:US191063

    申请日:1998-11-12

    IPC分类号: B29C35/02 B29D11/00

    CPC分类号: B29D11/00317 B29C35/02

    摘要: The invention relates to a process for the manufacture of tinted ophthalmic moldings comprising the steps of(a) providing a water soluble polymer precursor having crosslinkable or polymerizable groups;(b) providing a pigment dispersion comprising an inorganic or organic pigment and a dispersing agent;(c) mixing the metal phthalocyanine dye or pigment with the polymer precursor to form a tinted prepolymerization mixture,(d) dispensing the tinted prepolymerization mixture into a mold,(e) applying radiation to the tinted prepolymerization mixture in the mold, thereby crosslinking or polymerizing the polymer precursor and entrapping the dye or pigment within the polymeric network of the resultant ophthalmic molding, and(f) opening the mold so that the ophthalmic molding can be removed from the mold.According to the process, tinted ophthalmic moldings, particularly full-body tinted soft contact lenses having improved properties, are prepared with an improved efficiency.

    摘要翻译: 本发明涉及一种制造有色眼用模制品的方法,包括以下步骤:(a)提供具有可交联或可聚合基团的水溶性聚合物前体; (b)提供包含无机或有机颜料和分散剂的颜料分散体; (c)将金属酞菁染料或颜料与聚合物前体混合以形成着色的预聚合混合物,(d)将着色的预聚合混合物分配到模具中,(e)向模具中的着色预聚合混合物施加辐射,从而交联或 使聚合物前体聚合并将染料或颜料捕获到所得眼用模制品的聚合物网络内,和(f)打开模具,使得可以将模具从模具中移出。 根据该方法,以提高的效率制备着色眼用模制品,特别是具有改进性能的全身有色软触角镜。

    Storage-stable hydrogels
    10.
    发明授权
    Storage-stable hydrogels 有权
    储存稳定的水凝胶

    公开(公告)号:US6156244A

    公开(公告)日:2000-12-05

    申请号:US180588

    申请日:1998-11-12

    摘要: The present invention relates to a process for the preparation of storage-stable hydrogel mouldings, the storage stability of which can be established by controlled hydrolysis. At the same time as the sotrage stability is established, the hydrogel is sterilised in its final packaging, and the salt concentration of the aqueous phase is adjusted preferably to a physiological range.

    摘要翻译: PCT No.PCT / EP97 / 02477。 371日期:1998年11月12日 102(e)日期1998年11月12日PCT提交1997年5月15日PCT公布。 公开号WO97 / 44687 日期1997年11月27日本发明涉及一种制备储存稳定型水凝胶模塑制品的方法,其储存稳定性可通过可控制的水解来建立。 在稳定性稳定的同时,将水凝胶在其最终包装中灭菌,并将水相的盐浓度优选调节至生理范围。