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    Acoustic coupling gel for combined mammography and ultrasound image acquisition and methods thereof
    1.
    发明申请
    Acoustic coupling gel for combined mammography and ultrasound image acquisition and methods thereof 审中-公开
    用于组合乳腺摄影和超声图像采集的声耦合凝胶及其方法

    公开(公告)号：US20050288581A1

    公开(公告)日：2005-12-29

    申请号：US10879458

    申请日：2004-06-29

    申请人： Ajay Kapur ,  Kai Thomenius

    发明人： Ajay Kapur ,  Kai Thomenius

    IPC分类号： A61B6/00 ,  A61B6/04 ,  A61B8/00 ,  A61B8/08

    CPC分类号： A61B6/0414 ,  A61B6/4417 ,  A61B6/502 ,  A61B6/5247 ,  A61B8/0825 ,  A61B8/4281 ,  A61B8/4416

    摘要： In accordance with embodiments of the present technique, a combined mammography and ultrasound imaging system is provided. The system includes an ultrasound probe, which transmits ultrasound signals to a breast of a patient and receives reflected ultrasound signals from the breast. The system further includes a first acoustic coupling sheath. A first side of the first acoustic coupling sheath is coupled to a face of the ultrasound probe. The system also includes a mammography compression plate for compressing the breast of the patient. A second acoustic coupling sheath coupled to a side of the mammography compression plate contacts the breast of the patient.

    摘要翻译： 根据本技术的实施例，提供组合的乳房X线照相术和超声成像系统。 该系统包括超声波探头，其将超声波信号发送到患者的乳房，并从乳房接收反射的超声信号。 该系统还包括第一声耦合护套。 第一声​​耦合护套的第一侧耦合到超声波探头的面。 该系统还包括用于压缩患者乳房的乳房摄影压缩板。 耦合到乳房X射线摄影压缩板的一侧的第二声耦合护套接触患者的乳房。

    TRACKING AND OPTIMIZING GAIN AND CONTRAST IN REAL-TIME FOR ULTRASOUND IMAGING
    2.
    发明申请
    TRACKING AND OPTIMIZING GAIN AND CONTRAST IN REAL-TIME FOR ULTRASOUND IMAGING 审中-公开
    跟踪和优化实时增益和对比超声成像

    公开(公告)号：US20110054317A1

    公开(公告)日：2011-03-03

    申请号：US12551206

    申请日：2009-08-31

    申请人： Feng Lin ,  Suhyun Park ,  Xiaodong Tao ,  Mirsaid Seyed-Bolorforosh ,  Kai Thomenius ,  Menachem Halmann

    发明人： Feng Lin ,  Suhyun Park ,  Xiaodong Tao ,  Mirsaid Seyed-Bolorforosh ,  Kai Thomenius ,  Menachem Halmann

    IPC分类号： A61B8/14 ,  G06K9/00

    CPC分类号： G01S7/52033 ,  G01S7/52063 ,  G01S7/52077 ,  G06T5/008 ,  G06T2207/10132

    摘要： A system for dynamic optimization of gain and contrast in ultrasound imaging includes an image processor module programmed to dynamically estimate a correction profile in real-time and apply the correction profile to adjust a gain and contrast of image frame data sets. The image processor module is programmed to identify tissue and background regions in an image frame data set, determine an image intensity for each of the tissue and background regions, and formulate a gain profile based on the image intensity of the tissue region to compensate the gain variation of an image. The image processor module is further programmed to calculate an image contrast metric based on the image intensity of the tissue and background regions, and modify a gray map of the image frame data set based on the image contrast metric to adjust the contrast of an image displayed on the display system.

    摘要翻译： 用于超声成像中的增益和对比度的动态优化的系统包括被编程为实时动态地估计校正曲线的图像处理器模块，并应用校正轮廓来调整图像帧数据集的增益和对比度。 图像处理器模块被编程为识别图像帧数据集中的组织和背景区域，确定组织和背景区域中的每一个的图像强度，以及基于组织区域的图像强度来制定增益分布，以补偿增益 图像的变化。 图像处理器模块还被编程为基于组织和背景区域的图像强度来计算图像对比度量，并且基于图像对比度度量修改图像帧数据集的灰度图，以调整显示的图像的对比度 在显示系统上。

    Integrated interface electronics for reconfigurable sensor array
    3.
    发明申请
    Integrated interface electronics for reconfigurable sensor array 有权
    用于可重构传感器阵列的集成接口电子设备

    公开(公告)号：US20050094490A1

    公开(公告)日：2005-05-05

    申请号：US10977930

    申请日：2004-10-29

    申请人： Kai Thomenius ,  Rayette Fisher ,  Robert Wodnicki ,  William Burdick

    发明人： Kai Thomenius ,  Rayette Fisher ,  Robert Wodnicki ,  William Burdick

    IPC分类号： A61B8/00 ,  B06B1/02 ,  B06B1/06 ,  H04R17/00

    CPC分类号： B06B1/0292 ,  G01N29/06 ,  G01N29/262 ,  G01N2291/106 ,  H01L2924/0002 ,  H01L2924/00

    摘要： An integrated switch matrix for reconfiguring subelements of a mosaic sensor array to form elements. The configuration of the switch matrix is fully programmable. The switch matrix includes access switches that connect subelements to bus lines and matrix switches that connect subelements to subelements. Each subelement has a unit switch cell comprising at least one access switch, at least one matrix switch, a respective memory element for storing the future state of each switch, and a respective control circuit for each switch. The access and matrix switches are of a type having the ability to memorize control data representing the current switch state of the switch, which control data includes a data bit input to turn-on/off circuits incorporated in the control circuit. The sensor array and the switching matrix may be built in different strata of a co-integrated structure or they may be built on separate wafers that are electrically connected. If the sensors are arranged on a hexagonal grid, the unit switch cells may be arranged on either a hexagonal or rectangular grid.

    摘要翻译： 一种用于重新配置马赛克传感器阵列的子元素以形成元素的集成开关矩阵。 开关矩阵的配置是完全可编程的。 开关矩阵包括将子元件连接到总线线路的接入开关和将子元件连接到子元件的矩阵开关。 每个子元件具有包括至少一个存取开关，至少一个矩阵开关，用于存储每个开关的未来状态的相应存储元件以及每个开关的相应控制电路的单元开关单元。 存取和矩阵开关是具有存储表示开关的当前开关状态的控制数据的能力的类型，该控制数据包括输入到控制电路中的导通/截止电路的数据位。 传感器阵列和开关矩阵可以内置在共同一体化结构的不同层中，或者它们可以被构建在电连接的分开的晶片上。 如果传感器布置在六边形网格上，则单元开关单元可以布置在六边形或矩形网格上。

    Switching circuitry for reconfigurable arrays of sensor elements
    4.
    发明申请
    Switching circuitry for reconfigurable arrays of sensor elements 有权
    用于可重构阵列的传感器元件的开关电路

    公开(公告)号：US20050169107A1

    公开(公告)日：2005-08-04

    申请号：US10978196

    申请日：2004-10-29

    申请人： Kai Thomenius ,  Rayette Fisher ,  Robert Wodnicki ,  Christopher Hazard ,  Lowell Smith ,  David Mills

    发明人： Kai Thomenius ,  Rayette Fisher ,  Robert Wodnicki ,  Christopher Hazard ,  Lowell Smith ,  David Mills

    IPC分类号： A61B8/00 ,  B06B1/02 ,  B06B1/06 ,  H04R17/00 ,  E03B7/07 ,  F16K37/00 ,  F17D3/00 ,  G01S15/00 ,  H04B1/02

    CPC分类号： H03M11/00 ,  B06B1/0207 ,  B06B1/0292 ,  G01N29/262 ,  G01N2291/044 ,  G01N2291/106

    摘要： A device comprising an array of sensors that are reconfigurable by means of a switching network. The sensors may be optical, thermal or pressure sensors or ultrasonic transducers. More specifically, the device comprises: a multiplicity of sensor elements; a plurality of bus lines; a set of access switches for selectively connecting a set of the sensor elements in a row to a bus line, one of the access switches being connected to a first sensor element; a multiplicity of sets of matrix switches, each of the sets of matrix switches selectively connecting a respective sensor element of the multiplicity of sensor elements to a respective set of adjacent sensor elements, one of the matrix switches being connected to the first sensor element and to a second sensor element that is not a member of the set of sensor elements; and control circuitry that controls the access switches and the matrix switches in accordance with a selected switching configuration such that the first sensor element is connected to the bus line via said one access switch, while at the same time the second sensor element is connected to said one access switch via said one matrix switch.

    摘要翻译： 一种包括可通过交换网络重新配置的传感器阵列的设备。 传感器可以是光学，热或压力传感器或超声换能器。 更具体地，该装置包括：多个传感器元件; 多条总线; 一组接入开关，用于选择性地将一行中的传感器元件连接到总线，其中一个接入开关连接到第一传感器元件; 多个矩阵开关组，每组矩阵开关选择性地将多个传感器元件的相应传感器元件连接到相应的一组相邻传感器元件，矩阵开关中的一个连接到第一传感器元件，并且 第二传感器元件，其不是该组传感器元件的构件; 以及控制电路，其根据选择的开关配置来控制接入开关和矩阵开关，使得第一传感器元件经由所述一个接入开关连接到总线，同时第二传感器元件连接到所述 一个接入开关经由所述一个矩阵开关。

    Method and apparatus for ultrasonic continuous, non-invasive blood pressure monitoring
    5.
    发明申请
    Method and apparatus for ultrasonic continuous, non-invasive blood pressure monitoring 有权

    公开(公告)号：US20050154299A1

    公开(公告)日：2005-07-14

    申请号：US10749181

    申请日：2003-12-30

    申请人： Ralph Hoctor ,  Kai Thomenius ,  Aaron Dentinger ,  Jeremy McCarter

    发明人： Ralph Hoctor ,  Kai Thomenius ,  Aaron Dentinger ,  Jeremy McCarter

    IPC分类号： A61B5/021 ,  A61B8/04 ,  A61B8/00

    CPC分类号： A61B8/04 ,  A61B8/4236

    摘要： Ultrasound is used to provide input data for a blood pressure estimation scheme. The use of transcutaneous ultrasound provides arterial lumen area and pulse wave velocity information. In addition, ultrasound measurements are taken in such a way that all the data describes a single, uniform arterial segment. Therefore a computed area relates only to the arterial blood volume present. Also, the measured pulse wave velocity is directly related to the mechanical properties of the segment of elastic tube (artery) for which the blood volume is being measured. In a patient monitoring application, the operator of the ultrasound device is eliminated through the use of software that automatically locates the artery in the ultrasound data, e.g., using known edge detection techniques. Autonomous operation of the ultrasound system allows it to report blood pressure and blood flow traces to the clinical users without those users having to interpret an ultrasound image or operate an ultrasound imaging device.

    Determination of cellular electrical potentials
    7.
    发明授权
    Determination of cellular electrical potentials 有权
    细胞电位的测定

    公开(公告)号：US09370310B2

    公开(公告)日：2016-06-21

    申请号：US11654922

    申请日：2007-01-18

    申请人： Yao Chen ,  Kai Thomenius ,  Yongsheng Yang ,  Fei Teng ,  Yong Zhang ,  Jian Zhou ,  Joel Xue

    发明人： Yao Chen ,  Kai Thomenius ,  Yongsheng Yang ,  Fei Teng ,  Yong Zhang ,  Jian Zhou ,  Joel Xue

    IPC分类号： A61B5/0402 ,  A61B6/00 ,  A61B5/00 ,  A61B8/08

    CPC分类号： A61B5/0402 ,  A61B5/04028 ,  A61B5/725 ,  A61B5/7278 ,  A61B5/742 ,  A61B6/503 ,  A61B8/0883

    摘要： A method is provided for determining cellular electrical potentials using a state estimator. The state estimator is generated using at least an electrical source model and an electrical conduction model. One or more parameters or states of the state estimator are adjusted based on a measured electrocardiographic and/or a measured body-surface-potential signal. The electrical potential of one or more cells is determined based on the one or more adjusted parameters or states. In one aspect of the present technique, one or more representations of an organ comprising the one or more cells is generated such that the electrical potential or its deriving characteristic of the one or more cells is visually indicated.

    摘要翻译： 提供了一种使用状态估计器来确定细胞电位的方法。 状态估计器使用至少一个电源模型和电传导模型来产生。 基于测量的心电图和/或测量的体表电位信号来调整状态估计器的一个或多个参数或状态。 基于一个或多个调整的参数或状态来确定一个或多个单元的电位。 在本技术的一个方面，生成包含一个或多个细胞的器官的一个或多个表示，使得在视觉上指示一个或多个细胞的电位或其导出特征。

    FETAL HEART RATE MONITOR WITH WIDE SEARCH AREA
    8.
    发明申请
    FETAL HEART RATE MONITOR WITH WIDE SEARCH AREA 审中-公开
    极地心率监测器具有广泛的搜索区域

    公开(公告)号：US20110160591A1

    公开(公告)日：2011-06-30

    申请号：US12649735

    申请日：2009-12-30

    申请人： Lowell Smith ,  Mirsaid Seyed-Bolorforosh ,  Kai Thomenius ,  David Mills ,  Scott D. Cogan ,  Ashit Pandit ,  Srikanth Muthya

    发明人： Lowell Smith ,  Mirsaid Seyed-Bolorforosh ,  Kai Thomenius ,  David Mills ,  Scott D. Cogan ,  Ashit Pandit ,  Srikanth Muthya

    IPC分类号： A61B8/00

    CPC分类号： A61B8/0866 ,  A61B5/02411 ,  A61B8/02 ,  A61B8/4227 ,  A61B8/4472

    摘要： A continuous, non-invasive fetal heart rate measurement is produced using an ultrasound probe positioned on the abdomen of the mother. The ultrasound probe includes a plurality of ultrasound transducers that are positioned within a housing having a transmission surface. The transmission surface is configured to defocus the individual ultrasound beams created by the plurality of ultrasound transducers. The transmission surface defocuses the ultrasound beam and creates a wider area of coverage for the ultrasound probe. The controller contained within the heart rate monitor selectively activates different combinations of the plurality of ultrasound transducers to reduce the signal-to-noise ratio while allowing the ultrasound probe to locate the fetal heart beat and subsequently increase the signal-to-noise ratio during continuous heart rate monitoring.

    摘要翻译： 使用定位在母亲腹部的超声探头产生连续的非侵入性胎儿心率测量。 超声波探头包括多个超声换能器，其位于具有透射表面的壳体内。 传输表面被配置为使由多个超声换能器产生的各个超声波束聚焦。 传输表面使超声波束聚焦，并为超声波探头创建更广泛的覆盖区域。 包含在心率监测器内的控制器选择性地激活多个超声换能器的不同组合以降低信噪比，同时允许超声探头定位胎儿心跳，并且随后在连续期间增加信噪比 心率监测。

    Transmit and receive interface array for highly integrated ultrasound scanner
    9.
    发明申请
    Transmit and receive interface array for highly integrated ultrasound scanner 有权
    发射和接收接口阵列，用于高度集成的超声波扫描仪

    公开(公告)号：US20070016026A1

    公开(公告)日：2007-01-18

    申请号：US11172599

    申请日：2005-06-29

    申请人： Kai Thomenius ,  Robert Wodnicki ,  Ye-Ming Li

    发明人： Kai Thomenius ,  Robert Wodnicki ,  Ye-Ming Li

    IPC分类号： A61B8/00

    CPC分类号： G10K11/341 ,  A61B8/56 ,  G01S7/5208

    摘要： An ultrasonic transducer probe having a highly integrated interface circuit array. Low-voltage transmit control signals from the system are transmitted on the system transmit channels via the ultrasound probe cable and into the interface circuit array. These transmit control signals are routed through the interface circuit array using a dense switching matrix. Once the low-voltage transmit control signals reach individual cells within the interface array, they are decoded and used to control local high-voltage pulser circuits to drive individual ultrasound transducer elements made up of selected subelements that are co-integrated with the interface electronics. The interface cell circuitry further comprises a high-voltage transmit/receive switch, which is closed when the high-voltage pulser is transmitting to protect the low-voltage components.

    摘要翻译： 具有高度集成的接口电路阵列的超声换能器探针。 来自系统的低电压发射控制信号通过超声探头电缆在系统发射通道上传输到接口电路阵列中。 这些发送控制信号使用密集的交换矩阵通过接口电路阵列路由。 一旦低压发射控制信号到达接口阵列内的单个小区，就将它们解码并用于控制本地高压脉冲发生器电路，以驱动由与接口电子器件共同集成的选定子元件组成的各个超声换能器元件。 接口单元电路还包括高压发射/接收开关，当高压脉冲发生器正在传输时，该高压发射/接收开关闭合以保护低电压部件。